P104 Modulation of epigenetic mechanisms by dietary intervention in children with cow milk allergy

2018 ◽  
Vol 50 (4) ◽  
pp. e395
Author(s):  
L. Paparo ◽  
R. Nocerino ◽  
C. Di Scala ◽  
C. Bruno ◽  
G. Della Gatta ◽  
...  
Keyword(s):  
Dietary Intervention ◽  
Cow Milk ◽  
Epigenetic Mechanisms ◽  
Milk Allergy ◽  
Cow Milk Allergy

scholarly journals How Are Infants Suspected to Have Cow Milk Allergy Managed? A Real World Study Report

Nutrients ◽  
2021 ◽  
Vol 13 (9) ◽  
pp. 3027
Author(s):  
Yvan Vandenplas ◽  
Simona Belohlavkova ◽  
Axel Enninger ◽  
Pavel Frühauf ◽  
Niten Makwana ◽  
...  
Keyword(s):  
Primary Care ◽  
Dietary Intervention ◽  
Real Life ◽  
Gastrointestinal Symptoms ◽  
Cow Milk ◽  
Care Practice ◽  
Routine Practice ◽  
Milk Allergy ◽  
Diagnosis And Management ◽  
Cow Milk Allergy

The purpose of this study was to evaluate the diagnosis and management of infants presenting with symptoms attributable to cow milk allergy (CMA) in a real life setting and to test how the Cow Milk-related Symptom Score (CoMiSS®) can be used to support awareness and diagnosis of cow’s milk protein allergy in primary care practice. The CoMiSS is an awareness tool based on various symptoms such as crying, gastrointestinal symptoms, dermatological and respiratory symptoms. The study was conducted on 268 infants from four countries (Belgium, Czech Republic, Germany, UK) aged 0 to 18 months consulting for CMA related symptoms. The analysis was based on two visits of these subjects. The results show an average CoMiSS of 11 at the first visit. After a therapeutic dietary intervention, the score at the second visit, which happened 3 weeks ± 5 days after the first, dropped to an average value of 4. A satisfaction questionnaire completed by the primary care practitioners suggested an overall high level of satisfaction with the application of the CoMiSS tool in routine practice. These data highlight a huge discrepancy in the diagnosis and management of infants suspected of CMA in the different countries. The findings suggest that the CoMISS questionnaire is an effective tool in aiding awareness of CMPA in primary health care.

Screening for Cow Milk Allergy in Infants and Preschool Children

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Zeinab Awad El-Sayed ◽  
Hanan Mohamed Abdel-Lateef ◽  
Rasha Hassan El-Owaidy ◽  
Shady Sarwat Shaker
Keyword(s):  
Preschool Children ◽  
Challenge Test ◽  
Cow Milk ◽  
Diagnostic Tools ◽  
Milk Allergy ◽  
Cross Sectional ◽  
Oral Challenge Test ◽  
Egyptian Children ◽  
Cow Milk Allergy ◽  
History Of

Abstract Background Cow milk allergy (CMA) is the third most common food allergy that triggers anaphylactic reactions. Lactose intolerence, infantile colic and gastroesophageal reflux are the most common conditions which overlap with CMA causing both over and underdiagnosis. There are no wide population based epidemiological studies for the prevalence of CMA among Egyptian children. We sought to evaluate the prevalence of CMA among infants and preschool children and to correlate the parental reporting of CMA to the available diagnostic tools. Methods We conducted a cross sectional study that included 800 Egyptian children aged 3 months -5 years, who were enrolled consecutively from the primary care units and outpatient clinics of Children’s Hospital, Ain Shams University. Detailed history taking and clinical examination were done and those with suggestive history of CMA were subjected to further evaluation including skin prick test (SPT) and oral challenge test (OCT). Results The study comprised 390 girls (48.8%) and 410 boys (51.2%). Their weight centiles ranged between 5th and 97th percentiles, with median (IQR)=25(5-50) percentiles and mean(SD)=36.1(31.9). CM was introduced at age of 1-12 months, mean (SD): 9 (6) months with median (IQR): 12 (9-12) months. Forty (5%) subjects had suggestive history of CMA, 32 of whom completed their evaluation. The diagnosis of cow milk allergy was confirmed in 8/40 children (20%), comprising 1 % of the whole study sample. CMA was probably excluded at the time of the study in 21 subjects (52.5%), while diagnosis remained undetermined in 11/40 cases (27.5%) (8 refused to undergo SPT & OCT while 3 were lost to follow up). Conclusion The prevalence of CMA in Egyptian infants and preschool children is estimated to be around 1 % with possible overestimation of cow milk allergy diagnosis according to parental reports.

Value of immunologic tests in cow milk allergy

Allergy ◽  
1990 ◽  
Vol 45 (3) ◽  
pp. 189-196 ◽  
Author(s):  
V.-M. Tainio ◽  
E. Savilahti
Keyword(s):  
Cow Milk ◽  
Milk Allergy ◽  
Cow Milk Allergy ◽  
Immunologic Tests

scholarly journals Relation between Weak HLA-DR Expression on Human Breast Milk Macrophages and Cow Milk Allergy (CMA) in Suckling Infants

1999 ◽  
Vol 45 (1) ◽  
pp. 76-81 ◽  
Author(s):  
Kirsi-Marjut Järvinen ◽  
Kaisu Juntunen-Backman ◽  
Hanna Suomalainen
Keyword(s):  
Breast Milk ◽  
Cow Milk ◽  
Human Breast Milk ◽  
Milk Allergy ◽  
Human Breast ◽  
Hla Dr ◽  
Cow Milk Allergy

Matrix effect on baked milk tolerance in children with IgE cow milk allergy

2016 ◽  
Vol 44 (6) ◽  
pp. 517-523 ◽  
Author(s):  
S. Miceli Sopo ◽  
M. Greco ◽  
S. Monaco ◽  
A. Bianchi ◽  
B. Cuomo ◽  
...  
Keyword(s):  
Matrix Effect ◽  
Cow Milk ◽  
Milk Allergy ◽  
Cow Milk Allergy ◽  
Baked Milk

EFFICACY AND SAFETY OF HYDROLYZED COW MILK AND AMINO ACID-DERIVED FORMULAS IN INFANTS WITH COW MILK ALLERGY

PEDIATRICS ◽  
1996 ◽  
Vol 98 (2) ◽  
pp. 322-322
Author(s):  
Timothy Pham ◽  
Michael Kaplan
Keyword(s):  
Amino Acid ◽  
Normal Growth ◽  
Cow Milk ◽  
Food Allergies ◽  
Milk Allergy ◽  
Efficacy And Safety ◽  
Cow Milk Allergy

Extensively hydrolyzed formulas are safe and effective for most infants; amino acid-derived formulas may be preferable for infants with multiple food allergies, especially for the maintenance of normal growth.

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