Musculoskeletal manifestations of childhood cancer and differential diagnosis with juvenile idiopathic arthritis (ONCOREUM): a multicentre, cross-sectional study

2021 ◽  
Author(s):  
Adele Civino ◽  
Giovanni Alighieri ◽  
Eleonora Prete ◽  
Anna Maria Caroleo ◽  
Silvia Magni-Manzoni ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Juvenile Idiopathic Arthritis ◽  
Childhood Cancer ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Musculoskeletal Manifestations

scholarly journals Mandibular range of motion in children with juvenile idiopathic arthritis with and without clinically established temporomandibular joint involvement and in healthy children; a cross-sectional study

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Willemijn F. C. de Sonnaville ◽  
Caroline M. Speksnijder ◽  
Nicolaas P. A. Zuithoff ◽  
Daan R. C. Verkouteren ◽  
Nico W. Wulffraat ◽  
...  
Keyword(s):  
Juvenile Idiopathic Arthritis ◽  
Range Of Motion ◽  
Temporomandibular Joint ◽  
Cross Sectional Study ◽  
Joint Involvement ◽  
Healthy Children ◽  
Sectional Study ◽  
Cross Sectional ◽  
Explanatory Factors ◽  
Left And Right

Abstract Background Recognition of temporomandibular joint (TMJ) involvement in children with juvenile idiopathic arthritis (JIA) has gained increasing attention in the past decade. The clinical assessment of mandibular range of motion characteristics is part of the recommended variables to detect TMJ involvement in children with JIA. The aim of this study was to explore explanatory variables for mandibular range of motion outcomes in children with JIA, with and without clinically established TMJ involvement, and in healthy children. Methods This cross-sectional study included children with JIA and healthy children of age 6–18 years. Mandibular range of motion variables included active and passive maximum interincisal opening (AMIO and PMIO), protrusion, laterotrusion, dental midline shift in AMIO and in protrusion. Additionally, the TMJ screening protocol and palpation pain were assessed. Adjusted linear regression analyses of AMIO, PMIO, protrusion, and laterotrusion were performed to evaluate the explanatory factors. Two adjusted models were constructed: model 1 to compare children with JIA and healthy children, and model 2 to compare children with JIA with and without TMJ involvement. Results A total of 298 children with JIA and 169 healthy children were included. Length was an explanatory variable for the mandibular range of motion excursions. Each centimeter increase in length increased AMIO (0.14 mm), PMIO (0.14 mm), and protrusion (0.02 mm). Male gender increased AMIO by 1.35 mm. Having JIA negatively influenced AMIO (3.57 mm), PMIO (3.71 mm), and protrusion (1.03 mm) compared with healthy children, while the discrepancy between left and right laterotrusion raised 0.68 mm. Children with JIA and TMJ involvement had a 8.27 mm lower AMIO, 7.68 mm lower PMIO and 0.96 mm higher discrepancy in left and right laterotrusion compared to healthy children. Conclusion All mandibular range of motion items were restricted in children with JIA compared with healthy children. In children with JIA and TMJ involvement, AMIO, PMIO and the discrepancy between left and right laterotrusion were impaired more severely. The limitation in protrusion and laterotrusion was hardly clinically relevant. Overall, AMIO is the mandibular range of motion variable with the highest restriction (in millimeters) in children with JIA and clinically established TMJ involvement compared to healthy children.

scholarly journals Relationship of socio-economic status and childhood cancer: an in-hospital cross-sectional study in a developing country

1970 ◽  
Vol 44 (4) ◽  
pp. 180-184
Author(s):  
BJ Brown ◽  
AO Adeleye
Keyword(s):  
Childhood Cancer ◽  
Developing Country ◽  
Burkitt Lymphoma ◽  
Economic Status ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Health Seeking ◽  
Cross Sectional ◽  
Socio Economic Status ◽  
Health Seeking Behaviors

Background: Socioeconomic factors are known to affect health quality, disease occurrence as well as health-seeking behaviors in several ways.Objectives: To determine the influence of socio-economic factors on awareness of cancer, healthseeking behaviors among parents of children with cancer in a developing country and occurrence of cancer using Burkitt lymphoma as index malignancy.Methods: This was a descriptive cross-sectional study that involved children with cancer seen over a 2-year period in a tertiary hospital in Nigeria. Information was obtained by interview through administration of a questionnaire and retrieval of clinical data from patients’ case notes.Results: The caregivers of 91 children (46 boys, 45 girls) were interviewed including 86 biological parents. Majority (84.6%) of the children belonged to the low socio -economic classes 3-5; 45 of 86 parents (52.3%), more likely in parents from higher socioeconomic classes, were aware of cancer but only 7 (8.1%) knew it could occur in children. There was no association between Burkitt lymphoma and socio-economic class. Twenty-eight (30.8%) parents of the 91 children visited alternate sources of health care, most commonly traditional healers, followed by religious centers. There was no association between visits to such centers and the parents’ socio-economic status or with presentation with metastatic disease.Conclusions: Awareness of childhood cancer is low among this cohort of parents; their socioeconomic status seems to impact on this level of awareness but not on their health-seeking behaviors for their affected children. Focused health education is needed to increase childhood cancer awareness and appropriate healthseeking behavior among the population studied.Key words: socio-economic; childhood; cancer; health-seeking; behaviour; awareness

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