Combined Keyhole Craniotomies for Multifocal or Multiple Lesions

2021 ◽  
pp. 196-202
Author(s):  
Abigail Funari ◽  
Murray Echt ◽  
Vijay Agarwal
Keyword(s):  
Multiple Lesions

scholarly journals Implications of multiple late gadolinium enhancement lesions on the frequency of left ventricular reverse remodeling and prognosis in patients with non‐ischemic cardiomyopathy

2021 ◽  
Vol 23 (1) ◽  
Author(s):  
Shingo Ota ◽  
Makoto Orii ◽  
Tsuyoshi Nishiguchi ◽  
Mao Yokoyama ◽  
Ryoko Matsushita ◽  
...  
Keyword(s):  
Heart Failure ◽  
Late Gadolinium Enhancement ◽  
Ischemic Cardiomyopathy ◽  
Left Ventricular ◽  
Reverse Remodeling ◽  
Cardiac Events ◽  
Gadolinium Enhancement ◽  
Systolic Volume ◽  
Linear Pattern ◽  
Multiple Lesions

Abstract Background Non-ischemic cardiomyopathy (NICM) is a heterogeneous disease, and its prognosis varies. Although late gadolinium enhancement (LGE)-cardiovascular magnetic resonance (CMR) demonstrates a linear pattern in the mid-wall of the septum or multiple LGE lesions in patients with NICM, the therapeutic response and prognosis of multiple LGE lesions have not been elucidated. This study aimed to investigate the frequency of left ventricular (LV) reverse remodeling (LVRR) and prognosis in patients with NICM who have multiple LGE lesions. Methods This single-center retrospective study included 101 consecutive patients with NICM who were divided into 3 groups according to LGE-CMR results: patients without LGE (no LGE group = 48 patients), patients with a typical mid-wall LGE pattern (n = 29 patients), and patients with multiple LGE lesions (n = 24 patients). LVRR was defined as an increase in LV ejection fraction (LVEF) ≥ 10 % and a final value of LVEF > 35 %, which was accompanied by a decrease in LV end-systolic volume ≥ 15 % at 12-month follow-up using echocardiography. The frequency of composite cardiac events, defined as sudden cardiac death (SCD), aborted SCD (non-fatal ventricular fibrillation, sustained ventricular tachycardia, or adequate implantable cardioverter-defibrillator therapies), and heart failure death or hospitalization for worsening heart failure, were summarized and compared between the groups. Results Among the 3 groups, the frequency of LVRR was significantly lower in the multiple lesions group than in the no LGE and mid-wall groups (no LGE vs. mid-wall vs. multiple lesions: 49 % vs. 52 % vs. 19 %, p = 0.03). There were 24 composite cardiac events among the patients: 2 in patients without LGE (hospitalization for worsening heart failure; 2), 7 in patients of the mid-wall group (SCD; 1, aborted SCD; 1 and hospitalization for worsening heart failure; 5), and 15 in patients of the multiple lesions group (SCD; 1, aborted SCD; 8 and hospitalization for worsening heart failure; 6). The multiple LGE lesions was an independent predictor of composite cardiac events (hazard ratio: 11.40 [95 % confidence intervals: 1.49−92.01], p = 0.020). Conclusions Patients with multiple LGE lesions have a higher risk of cardiac events and poorer LVRR. The LGE pattern may be useful for an improved risk stratification in patients with NICM.

scholarly journals Clinical characteristics and outcomes of primary versus secondary gastrointestinal mantle cell lymphoma

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Alessia Castellino ◽  
Aung M. Tun ◽  
Yucai Wang ◽  
Thomas M. Habermann ◽  
Rebecca L. King ◽  
...  
Keyword(s):  
Mantle Cell Lymphoma ◽  
Cell Lymphoma ◽  
Performance Status ◽  
International Prognostic Index ◽  
Prognostic Index ◽  
Local Therapy ◽  
Progression Free Survival ◽  
Cell Transplant ◽  
Multiple Lesions ◽  
Mantle Cell

AbstractPrimary gastrointestinal (GI) mantle cell lymphoma (MCL) is rare and the optimal management is unknown. We reviewed 800 newly diagnosed MCL cases and found 22 primary (2.8%) and 79 (9.9%) secondary GI MCL cases. Age, sex, and performance status were similar between primary and secondary cases. Secondary cases had more elevations in lactate dehydrogenase (28% vs 0%, P = 0.03) and a trend for a higher MCL international prognostic index (P = 0.07). Observation or local therapy was more common for primary GI MCL (29% vs 8%, P < 0.01), and autologous stem-cell transplant was more common for secondary GI MCL (35% vs 14%, P < 0.05). The median follow-up was 85 months. Primary and secondary GI MCL had similar 5-year progression-free survival (PFS) (30% vs 28%, P = 0.59) and overall survival (OS) (65% vs 66%, P = 0.83). The extent of GI involvement in primary GI MCL affected treatment selection but not outcome, with a 5-year PFS of 43% vs 14% vs 31% (P = 0.48) and OS of 57% vs 71% vs 69% (P = 0.54) in cases with single lesion vs multiple lesions in 1 organ vs multiple lesions in ≥2 organs. Less aggressive frontline treatment for primary GI MCL is reasonable. It is unknown whether more aggressive treatment can result in improved outcomes.

Multiple lesions of primary cutaneous nodular amyloidosis in Sjögren syndrome

2012 ◽  
Vol 67 (6) ◽  
pp. e267-e268 ◽  
Author(s):  
Allison J. Brown ◽  
Kerith E. Spicknall ◽  
Diya F. Mutasim
Keyword(s):  
Sjögren Syndrome ◽  
Sjogren Syndrome ◽  
Multiple Lesions

Automatic diagnosis of multiple lesions in fundus images based on dual attention mechanism

2021 ◽  
Author(s):  
Jiamin Gong ◽  
Liufei Guo ◽  
Jiewei Jiang ◽  
Chengchao Wu ◽  
Mengjie Pei ◽  
...  
Keyword(s):  
Attention Mechanism ◽  
Fundus Images ◽  
Automatic Diagnosis ◽  
Multiple Lesions

Linea Vestibularis: A Previously Undescribed Normal Genital Structure in Female Neonates

PEDIATRICS ◽  
1991 ◽  
Vol 87 (6) ◽  
pp. 926-929
Author(s):  
NANCY D. KELLOGG ◽  
JUAN M. PARRA
Keyword(s):  
Sexual Abuse ◽  
Anatomical Variations ◽  
White Area ◽  
Multiple Lesions ◽  
Single Entity ◽  
Female Children ◽  
Genital Structure

The increasing number of evidentiary examinations conducted for sexual abuse has accentuated the importance of defining normal genital anatomy, particularly within the vestibule of female children. In female newborns, normal anatomical variations of the hymen have been described1,2 but anatomical variations of the posterior vestibule underlying the hymen have not been reported. In children evaluated for sexual abuse a vestibular structure of varying description and location has been reported. A "midline avascular streak," "scar," and "a white area" have been noted in the posterior vestibule, posterior fourchette, and hymen.1,3,4 Whether these descriptions all pertain to a single entity or are multiple lesions is not known.

scholarly journals Case Report: Rare Pulmonary Sclerosing Pneumocytoma: Large, Multiple, Metastatic, and Fatal

2021 ◽  
Vol 8 ◽  
Author(s):  
Weidong Zhang ◽  
Yuanyuan Liu ◽  
Yamei Chai ◽  
Kefeng Shi ◽  
Jialing Chen ◽  
...  
Keyword(s):  
Case Report ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Malignant Tumor ◽  
Abdominal Cavity ◽  
Low Grade ◽  
Node Metastasis ◽  
Multiple Lesions ◽  
Extra Pulmonary ◽  
First Time

Pulmonary sclerosing pneumocytoma (PSP) is a rare benign or low-grade malignant tumor, but it has the potential to present with multiple lesions, lymph node metastasis, extra-pulmonary metastasis, recurrence and even cause death. Herein, a case of PSP that was huge, presented with multiple lesions and had lymph node as well as extrapulmonary metastases (liver, abdominal cavity, bones) is reported for the first time. This patient was also the first one to die of respiratory and circulatory failure caused by the PSP tumor and its metastases which compressed the mediastinal tissue.

scholarly journals Low-Grade Malignancy Glomus Tumor in a Setting of Multiple Glomus Tumors – Case Report

2019 ◽  
Vol 7 (23) ◽  
pp. 4082-4088
Author(s):  
Violeta Vasilevska-Nikodinovska ◽  
Milan Samardjiski ◽  
Rubens Jovanovik ◽  
Boro Ilievski ◽  
Vesna Janevska
Keyword(s):  
Glomus Tumor ◽  
Subcutaneous Tissue ◽  
Vena Cava ◽  
Malignant Potential ◽  
Biological Behavior ◽  
Low Grade ◽  
Uncertain Malignant Potential ◽  
Glomus Tumors ◽  
Small Nodule ◽  
Multiple Lesions

BACKGROUND: Glomus tumors are rare neoplasms accounting for less than 2% of all soft tissue tumors but multiple lesions may be seen in up to 10% of the patients. Solitary glomus tumor (GT) most frequently appears as small nodule in specific locations such as subungual region or deep dermis. However, rarely these entities have been observed in extracutaneous locations such as the gastrointestinal, cardiovascular, respiratory tracts, and other visceral organs. A small fraction of the GTs may present as tumors of uncertain malignant potential or as malignant glomus tumors. CASE PRESENTATION: We report a patient with multiple glomus tumors on the time of diagnosis, which was histologically diagnosed as an atypical glomus tumor following resection of a tumor thrombus in the left renal vein, inferior vena cava trombus with intracardial extension, and mitral valve specimen. The intramuscular lesion from the thigh was diagnosed as a glomus tumor of uncertain malignant potential. Further examinations revealed multiple lesions trough her body: kidneys, breast, heart and subcutaneous tissue. The diagnosis of glomus tumor of uncertain malignant potential versus glomus tumor with low malignant potential could be quite challenging, and the clinical course may be as a determining factor for final diagnosis. CONCLUSION: To our knowledge, this is the only known case of glomus tumor with multiple organ involvement and aggressive biological behavior at presentation.

Scrotal Carcinoid: Presenting Manifestation of Multiple Lesions in the Small Intestine

1991 ◽  
Vol 96 (5) ◽  
pp. 664-668 ◽  
Author(s):  
Ronna F. Lodato ◽  
Gregory J. Zentner ◽  
Cosme A. Gomez ◽  
Lucien E. Nochomovitz
Keyword(s):  
Small Intestine ◽  
Multiple Lesions
Sign in / Sign up

Export Citation Format

Share Document