Vitamin B Complex: Thiamine, Riboflavin, Niacin, Pantothenic Acid, Pyridoxine, Cobalamin, Folic Acid

Author(s):  
Daphne A. Roe
1984 ◽  
Vol 51 (1) ◽  
pp. 37-50 ◽  
Author(s):  
K. John Scott ◽  
Dinah R. Bishop ◽  
Alicja Zechalko ◽  
John D. Edwards-Webb ◽  
Patricia A. Jackson ◽  
...  

SummaryA survey was undertaken to update and extend available information on the vitamin content of pasteurized milk as produced at processing dairies in mainland UK and to investigate regional, seasonal and breed effects. The concentration of total retinol in milk from non-Channel Island (NCI) breeds averaged 61·9 βg/100g in summer and 41·2 βg/100g in winter. Concentrations of β-carotene were 31·5 and 10·5 βg/100g in summer and winter respectively. Concentrations of retinol in milk from Channel Island (CI) breeds were similar, but concentrations of β-carotene were on average 3 times higher. The concentration of vitamin D3 in milk from NCI breeds was 0·033 βg/100g in summer and 0·026 βg/100g in winter. There was no marked seasonal variation in the mean concentration of total vitamin C (14·5 βg/ml). Values for the concentration of B vitamins (βg/ml) were: folic acid 0·060, vitamin B12 0·0042, riboflavin 1·78, nicotinic acid 0·71, pantothenic acid 3·60, biotin 0·020, thiamin 0·46 and vitamin B6 0·61. Seasonal variation in the concentration was most marked for folic acid (c.v. 17·4%) and to a lesser extent for vitamin B12 (c.v. 10·3%). The only breed differences in the B vitamin content were for riboflavin and folic acid, the mean values obtained for milk from CI breeds being respectively 20 and 10 % higher than those from NCI breeds.


1974 ◽  
Vol 31 (2) ◽  
pp. 185-200 ◽  
Author(s):  
A. Tolan ◽  
Jean Robertson ◽  
C. R. Orton ◽  
M. J. Head ◽  
A. A. Christie ◽  
...  

1. The nutrient content of battery, deep litter and free range eggs from domestic hens under systems of management typical of those used in the commercial production of eggs was studied from January to March 1968.2. Monthly samples of eighteen eggs, supplied by six centres, were homogenized, freezedried, ground and stored at −15°. Their contents of moisture, nitrogen, amino acids, fats, fatty acids and cholesterol, ash, sodium, potassium, calcium and iron, thiamin, riboflavin, nicotinic acid, pantothenic acid, folic acid, vitamin B12, tocopherols and retinol were determined. The mean values for eggs from each system, each centre and each quarter of the year were calculated.3. For many nutrients, no significant difference between systems was detected; the greatest variations occurred in the content of some vitamins. Free range eggs contained more vitamin B12 than deep litter or battery eggs and more folic acid (Lactobacillus casei assay) than battery eggs. Differences in tocopherol and cholesterol contents were complicated by system-by-centre interactions. There were also small differences in calcium and iron contents.4. Riboflavin, folic acid (Lactobacillus casei) and vitamin B12 were the only nutrients which were observed to vary with the time of year in the eggs from all systems of management. Major differences were found in the vitamin content of eggs from different centres.5. Though the differences in vitamin B12 and folic acid contents which result from the different systems of management are of little significance in an average mixed diet, they would be measurable for some individuals who may depend on eggs as an important source of these nutrients.


1957 ◽  
Vol 3 (1) ◽  
pp. 35-42 ◽  
Author(s):  
A. G. Lochhead ◽  
Margaret O. Burton

A relatively high proportion of the indigenous bacteria of a field soil (27.1%, corresponding to 14.1 millions/g.) required one or more vitamins for growth. The vitamins found to be essential, either alone or with others, were, in order of frequency, thiamine, biotin, vitamin B12, pantothenic acid, folic acid, nicotinic acid, and riboflavin. In all, 16 different 'patterns' were noted for vitamin requirements, the number of vitamins needed by individual strains ranging from one to five. The findings point to the soil as an important habitat of vitamin-requiring bacteria, many of which show potentiality as assay organisms. Their occurrence in the numbers found indicates that growth-factors should receive equal emphasis with antibiotics in problems involving the microbial equilibrium in soil and interrelationships between the normal soil microflora, soil-borne disease organisms, and growing plants.


2020 ◽  
Vol 16 (S3) ◽  
Author(s):  
Yvette Wilda Jyrwa ◽  
Ravindranadh Palika ◽  
Swetha Boddula ◽  
Naveen Kumar Boiroju ◽  
Radhika Madhari ◽  
...  

1965 ◽  
Vol 43 (8) ◽  
pp. 1367-1374 ◽  
Author(s):  
P. L. McGeer ◽  
N. P. Sen ◽  
D. A. Grant

The excretion of 4(5)-amino-5(4)-imidazolecarboxamide (AIC) in the urines of normal rats, rats raised on a folic acid deficient diet, and rats raised on a vitamin B12 deficient diet was measured. The AIC excretion was elevated 3-fold above normal in the B12 deficient group and 1.5-fold above normal in the folic acid deficient group.No evidence could be found that the raised AIC excretion was associated with a block in the conversion of AIC to purines. The recovery of radioactive AIC in the urine after an intraperitoneal dose of 2 μmoles AIC per kg was not increased over normal in any of the deficient groups, and was significantly less than normal in the B12-deficient group. Most of the urinary radioactivity in all groups was in allantoin, uric acid, and purines.When a load of 220 μmoles of AIC per kg was administered there was no difference between the vitamin B12 deficient and the normal groups in AIC recovery in the urine. When a load of 220 μmoles of urocanic acid per kg was administered, however, the B12-deficient group had an 18-fold increase over normal in Figlu excretion, and the folic acid deficient group a 17-fold increase. Thus, a substantial block in formimino-L-glutamic acid (Figlu) metabolism, but not in AIC metabolism, existed in the vitamin-deficient groups.Feeding a B12-deficient group a 2% methionine supplement reduced the Figlu excretion after a urocanic acid load to less than half that observed in B12-deficient groups without methionine supplementation, but had no influence on the AIC excretion.


Author(s):  
Ralph Green ◽  
Joshua W. Miller

AbstractPrevalence rates for folate deficiency and hyperhomocysteinemia have been markedly reduced following the introduction of folic acid fortification in the United States. We report the prevalence of hyperhomocysteinemia in a population of community-dwelling elderly Latinos in the post-folic acid fortification era. We measured homocysteine, total vitamin B


1993 ◽  
Vol 27 (1) ◽  
pp. 59-64 ◽  
Author(s):  
F. S. Venter ◽  
H. Cloete ◽  
J. V. Seier ◽  
M. J. Faber ◽  
J. E. Fincham

Plasma and red blood cell (RBC) folic acid levels, as well as plasma vitamin B12 levels were determined in Vervet monkeys ( Cercopithecus aethiops). All the vervets were apparently healthy and without symptoms or lesions typical of folic acid and/or vitamin B12 deficiencies. Competitive protein binding radioassays were used to determine folate and vitamin B12 values in animals fed 4 different diets. The B12 levels for all the groups ranged between 866 and 5867 pg/ml and showed an inverse relationship with the FA measurements. The lowest mean RBC folic acid content in a group fed an atherogenic diet for 3 years was 12·8 ng/ml. For the other 3 diets, mean RBC folic acid levels were 90·7, 132·3 and 152·8 ng/ml, respectively. A megadose of 25·6 mg of folic acid per day for 99 days was given to 3 adult males. No obvious toxic effects were observed in these animals although mean RBC folic acid levels increased to 1013 ng/ml.


1969 ◽  
Vol 36 (3) ◽  
pp. 447-454 ◽  
Author(s):  
J. E. Ford ◽  
J. W. G. Porter ◽  
S. Y. Thompson ◽  
Joyce Toothill ◽  
J. Edwards-Webb

SummaryThe vitamin content of ultra-high-temperature (UHT) processed milk was compared with that of the original raw milk. Three processes were used. In the first, which caused no change in oxygen content, the milk was heated and cooled in a plate-type heat exchanger. In the second, the milk was again heated indirectly and then evaporatively cooled, leaving in the milk about one-third of the initial oxygen content. In the third process the milk was heated by direct steam injection and cooled by evaporation and contained little or no residual oxygen.On processing and during subsequent storage for 90 days there was no loss of vitamin A, carotene, vitamin E, thiamine, riboflavine, pantothenic acid, biotin or nicotinic acid. There was little or no loss of vitamin B6or vitamin B12on processing, but up to 50% of each of these vitamins was lost during 90 days' storage. All the dehydroascorbic acid (DHA) and about 20% of the ascorbic acid (AA) was lost on processing. There was no further loss of AA during 90 days’ storage when no residual oxygen was present, but in milks containing more than about 1 ppm oxygen all the AA was lost within 14 days. About 20% of the folic acid was lost on processing; thereafter, as with ascorbic acid, the extent of the loss on storage depended on the residual oxygen content of the milk: in the absence of oxygen the folic acid was stable.


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