scholarly journals 3465 EXAMINING THE EFFECTS OF CHILDHOOD TRAUMA ON ADULT ALCOHOL CONSUMPTION: DOES RACE AND/OR SEX MATTER?

2019 ◽  
Vol 3 (s1) ◽  
pp. 44-44
Author(s):  
Nia Byrd ◽  
Bethany Stangl ◽  
Melanie Schwandt ◽  
Mehdi Farokhnia ◽  
Lorenzo Leggio ◽  
...  
Keyword(s):  
Alcohol Consumption ◽  
Alcohol Use ◽  
Physical Abuse ◽  
Emotional Abuse ◽  
Heavy Drinking ◽  
Interaction Effects ◽  
Negative Effects ◽  
Harmful Use ◽  
Physical Neglect ◽  
Dependent Sample

OBJECTIVES/SPECIFIC AIMS: There has been substantial research showing that there are race and sex differences on alcohol use. Similarly, race and sex disparities are also seen in a variety of different factors that impact drinking behaviors and other health outcomes. One of these factors of interest is Adverse Childhood Experiences (ACEs) which is associated with an increased risk for excessive alcohol use and the harmful effects of drinking. Several studies have shown that racial minorities and females have a greater risk of ACEs, which may be partly related to various structural factors (i.e. poverty) and social norms. Although there has been a substantial amount of research done on ACEs, very few studies have looked at how their interaction with race and sex can influence alcohol-related behaviors. METHODS/STUDY POPULATION: 1,509 participants who self-identified as either Black or White were recruited through a screening protocol at the NIAAA where they completed a series of questionnaires. We categorized the participants into two groups based on the Structured Clinical Interview for DSM-IV disorders: Alcohol Dependent individuals (N=921) with either a past and/or current diagnosis and Non-dependent individuals (N=588). ACEs exposure was assessed using the Childhood Trauma Questionnaire (CTQ). We looked at both total score and the 5 subscales: emotional abuse, physical abuse, sexual abuse, physical neglect, and emotional neglect. Drinking behaviors were assessed using a 90-day Timeline Followback interview and the Alcohol Use Disorder Identification Test (AUDIT). The non-dependent sample was 63% White and 55% male while the alcohol dependent sample was 47% White and 70% male. We tested the interaction effects using ANOVA. RESULTS/ANTICIPATED RESULTS: In the ND sample, there were significant race*sex*ACEs effects for average drinks per day with CTQ total score (P = 0.007), physical abuse (P = 0.005), and physical neglect (P = 0.003). There was also a 3-way interaction with physical neglect on heavy drinking days (P = 0.039) and a 2-way race*ACEs interaction on AUDIT total with physical abuse (P = 0.048). In the AD sample, there were significant 2-way race*ACEs interactions for three drinking outcomes: heavy drinking days with physical neglect (P = 0.009), AUDIT-Harmful Use subscore with CTQ total score (P = 0.028) and physical neglect (P = 0.001), AUDIT-Total score with CTQ total score (P = 0.007), physical abuse (P = 0.042), sexual abuse (P = 0.024), and physical neglect (P = 0.003). There were also 3-way interactions for AUDIT-Harmful use (P = 0.013) and AUDIT-Total scores (P = 0.011) with emotional abuse. DISCUSSION/SIGNIFICANCE OF IMPACT: Our results indicate that there are both 2-way (race*ACEs) and 3-way (race*sex*ACEs) interaction effects on alcohol consumption and the related negative effects for both non-dependent and dependent samples. There were no sex*ACEs interaction effects in either sample implying that race may play a bigger role in differentiating drinking outcomes by ACEs across males and females. However, contrary to our expectations, race seemed to be protective factor for Black participants against both alcohol consumption and the negative effects despite having higher rates of ACEs exposure. Future analyses will explore personality measures as potential mediators of the relationship between ACEs and alcohol use. Also, analyses will look to see if there are any behavioral factors that may contribute to resiliency among minority populations.

scholarly journals 4491 Cumulative Childhood Trauma Load Across Race in Individuals with Alcohol Use Disorder

2020 ◽  
Vol 4 (s1) ◽  
pp. 26-27
Author(s):  
Nia Byrd ◽  
Bethany L. Stangl ◽  
Melanie L. Schwandt ◽  
Nancy Diazgranados ◽  
Vijay A. Ramchandani
Keyword(s):  
Alcohol Use ◽  
Physical Abuse ◽  
Racial Differences ◽  
Childhood Trauma ◽  
Emotional Abuse ◽  
Alcohol Use Disorder ◽  
Heavy Drinking ◽  
Emotional Neglect ◽  
Childhood Trauma Questionnaire ◽  
Physical Neglect

OBJECTIVES/GOALS: Our objective was to investigate racial differences in experiencing multiple categories of childhood trauma (CT) and the differential impact on alcohol use in individuals with alcohol use disorder (AUD). We hypothesized that there would be a differential additive effect of CT categories endorsed and drinking behaviors between racial groups. METHODS/STUDY POPULATION: Participants were recruited through the NIAAA screening protocol where they completed alcohol-related assessments including a 90-day Timeline Followback (TLFB) and the Alcohol Use Disorder Identification Test (AUDIT). Structured Clinical Interviews for DSM disorders were conducted to identify participants with lifetime alcohol dependence (DSM-IV) or AUD (DSM-5) (N = 1152). Participants self-identified as Black or White completed the Childhood Trauma Questionnaire (CTQ) which assesses 5 types of CT: emotional abuse, physical abuse, sexual abuse, physical neglect, and emotional neglect, and were classified into 3 CT groups: no trauma, 1 type of trauma, and 2+ types of trauma endorsed. RESULTS/ANTICIPATED RESULTS: For Black participants (N = 583), 21.6% experienced no trauma, 21% experienced 1 type, and 57.4% experienced 2 or more types, with the most common being physical abuse and emotional neglect. For White participants (N = 569), 32.1% experienced no trauma, 20.6% experienced 1 type, and 47.3% experienced 2 or more types, with the most common being emotional neglect and emotional abuse. There were significant associations between CT groups, TLFB, and AUDIT measures. For Black participants, AUDIT-Harm and AUDIT Total were significantly different across the 3 CT groups (all p values <0.05). For White participants, Heavy Drinking Days was significantly different across the 3 CT groups (p = 0.028), with trends for AUDIT-Harm (p = 0.061) and AUDIT-Dependence (p<0.065). DISCUSSION/SIGNIFICANCE OF IMPACT: In individuals with AUD, there were significant positive associations between the number of CT categories endorsed and alcohol use across race, suggesting a cumulative effect of CT on risky alcohol use. Future work includes exploring personality and behavioral mediators of the relationship between cumulative trauma load and drinking.

Nalmefene against alcohol use disorder: A report of one case

2017 ◽  
Vol 41 (S1) ◽  
pp. s866-s866
Author(s):  
M. Juncal Ruiz ◽  
O. Porta Olivares ◽  
L. Sánchez Blanco ◽  
R. Landera Rodríguez ◽  
M. Gómez Revuelta ◽  
...  
Keyword(s):  
Alcohol Consumption ◽  
Alcohol Use ◽  
Opioid Receptor ◽  
Treatment Option ◽  
Withdrawal Syndrome ◽  
Alcohol Use Disorder ◽  
Alcohol Intake ◽  
Family Relationship ◽  
Heavy Drinking ◽  
Alcohol Withdrawal Syndrome

IntroductionAlcohol consumption represents a significant factor for mortality in the world: 6.3% in men and 1.1% in women. Alcohol use disorder is also very common: 5.4% in men and 1.5% in women. Despite its high frequency and the seriousness of this disorder, only 8% of all alcohol-dependents are ever treated. One potentially interesting treatment option is oriented toward reducing alcohol intake.AimsTo describe one case who has improved his alcohol consumption after starting treatment with nalmefene, an opioid receptor antagonist related to naltrexone.MethodsA 35-year-old male with alcohol use disorder since 2001 came to our consult in November 2015. He was in trouble with his family and he had a liver failure. We offer a new treatment option with nalmefene 18 mg to reduce alcohol consumption.ResultsBefore to start nalmefene he drank 21 drinks/week. Six-month later, he decreased alcohol intake until 5 drinks/week with better family relationship and liver function. After starting nalmefene he complained of nausea, so we recommend to take the middle of the pill for next 7 days. After this time he returned to take one pill with good tolerance and no more side effects or withdrawal syndrome.ConclusionsNalmefene appears to be effective and safe in reducing heavy drinking and in preventing alcohol withdrawal syndrome due to its opioid receptor antagonism. This case suggests nalmefene is a potential option to help patients, who do not want or cannot get the abstinence, in reducing their alcohol consumption.Disclosure of interestThe authors have not supplied their declaration of competing interest.

scholarly journals Heavy alcohol consumption in individuals with HIV infection: Effects on neuropsychological performance

2005 ◽  
Vol 11 (1) ◽  
pp. 70-83 ◽  
Author(s):  
JOHANNES C. ROTHLIND ◽  
TANYA M. GREENFIELD ◽  
ANNE V. BRUCE ◽  
DIETER J. MEYERHOFF ◽  
DEREK L. FLENNIKEN ◽  
...  
Keyword(s):  
Alcohol Consumption ◽  
Alcohol Use ◽  
Executive Functioning ◽  
Hiv Infection ◽  
Synergistic Effects ◽  
Heavy Drinking ◽  
Heavy Alcohol ◽  
Heavy Drinkers ◽  
Heavy Alcohol Use ◽  
Active Alcohol

Higher rates of alcohol use have been reported in HIV+ individuals compared to the general population. Both heavy alcohol use and HIV infection are associated with increased risk of neuropsychological (NP) impairment. We examined effects of heavy active alcohol use and HIV on NP functioning in a large sample of community-residing HIV+ individuals and HIV− controls. The four main study groups included 72 HIV− light/non-drinkers, 70 HIV− heavy drinkers (>100 drinks per month), 70 HIV+ light/non-drinkers, and 56 HIV+ heavy drinkers. The heavy drinking group was further subdivided to assess effects of the heaviest levels of active alcohol use (>6 drinks per day) on NP functioning. A comprehensive NP battery was administered. Multivariate analysis of covariance was employed to examine the effect of HIV and alcohol on NP functioning after adjusting for group differences in age and estimated premorbid verbal intellectual functioning. The analyses identified main effects of heavy drinking and HIV on NP function, with greatest effects involving the contrast of HIV+ heavy drinkers and the HIV− light drinkers. Synergistic effects of heaviest current drinking and HIV infection were identified in analyses of motor and visuomotor speed. Supplementary analyses also revealed better NP function in the HIV+ group with antiretroviral treatment (ART) and lower level of viral burden, a finding that was consistent across levels of alcohol consumption. Finally, heavy alcohol use and executive functioning difficulties were associated with lower levels of self-reported medication adherence in the HIV+ group. The findings suggest that active heavy alcohol use and HIV infection have additive adverse effects on NP function, that they may show synergistic effects in circumstances of very heavy active alcohol use, and that heavy drinking and executive functioning may mediate health-related behaviors in HIV disease. (JINS, 2005, 11, 70–83.)

scholarly journals Evaluation of childhood traumatic experience as a risk factor for alcohol use disorder in adulthood

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Lan Wang ◽  
Cui-Xia An ◽  
Mei Song ◽  
Na Li ◽  
Yuan-Yuan Gao ◽  
...  
Keyword(s):  
Risk Factors ◽  
Alcohol Use ◽  
Alcohol Abuse ◽  
Alcohol Dependence ◽  
Physical Abuse ◽  
Emotional Abuse ◽  
Alcohol Use Disorder ◽  
Alcohol Use Disorders ◽  
Traumatic Experience ◽  
Frequent Drinking

Abstract Background We aimed to investigate the effect of early-age (prenatal, infant, and childhood) trauma on adulthood alcohol use disorder. Methods A total number of 1534 subjects who were born and live in the city of Tangshan were selected. The subjects were divided into three age groups. General demographic data, conditions of the mothers during pregnancy, and condition of the babies at birth, were collected. The diagnosis of alcohol use disorder was based on Structured Clinical Interviews for DSM-IV Axis Disorders (patient version) (SCID). The childhood trauma questionnaire short form (CTQ-SF) [1] and the Lifetime of Experience Questionnaire (LTE-Q) [2] were used to evaluate stress in childhood and adulthood, respectively. Results Only male subjects were diagnosed with lifelong alcohol abuse and alcohol dependence. There was no statistically significant difference in the prevalence of lifetime alcohol use disorder (X2 = 4.480, P = 0.345), current alcohol abuse, and current alcohol dependence among the three groups (X2abuse = 2.177, X2depedence = 2.198, P > 0.05). However, higher prevalence of lifetime alcohol use disorders was found in group with higher scores of CTQ (X2 = 9.315, P = 0.009), emotional abuse (X2 = 8.025, P = 0.018), physical abuse (X2 = 20.4080, P < 0.001), but not in the group with higher scores of emotional neglect (X2 = 1.226, P = 0.542), sexual abuse (X2 = 2.779, P = 0.249), physical neglect (X2 = 3.978, P = 0.137), LTE-Q (X2 = 5.415, P = 0.067), and PSQI (X2 = 5.238, P = 0.073). Protective factor for alcohol abuse for men was identified to be heavy drinking (OR = 0.085, 95%CI: 0.011–0.661), and the risk factors for alcohol abuse were identified to be frequent drinking (OR = 2.736, 95%CI: 1.500, 4.988), and consumption of low liquor (OR = 2.563, 95%CI: 1.387, 4.734). Risk factors for alcohol dependence in males were identified to be consumption of low liquor (OR = 5.501, 95%CI: 2.004, 15.103), frequent drinking (OR = 2.680, 95%CI: 1.164, 6.170), and childhood physical abuse (OR = 2.310, 95% CI: 1.026, 5.201). Conclusion Traumatic experience during infant and prenatal periods does not have a strong statistical correlation with alcohol use disorders for male adults. However, subjects with high CTQ scores, experience of emotional abuse and physical abuse show a statistically higher prevalence of lifetime alcohol use disorders. Several risk factors including consumption of low liquor, frequent drinking, and childhood physical abuse contribute to alcohol dependence in male adults.

scholarly journals Adverse childhood experiences and their relationship to gender and depression among young adults in Iraq: a cross-sectional study

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Ameel F. Al Shawi ◽  
Yassen T. Sarhan ◽  
Mahasin A. Altaha
Keyword(s):  
Young Adults ◽  
Physical Abuse ◽  
Adverse Childhood Experiences ◽  
Emotional Abuse ◽  
Statistical Tests ◽  
Emotional Neglect ◽  
Convenience Sample ◽  
Childhood Experiences ◽  
Adverse Childhood ◽  
Physical Neglect

Abstract Background Adverse childhood experiences (ACEs) are considered as universal public health problem that associate with mental disorders and risky behaviors during adulthood. The aims of the paper are to estimate the prevalence of Adverse childhood experiences (ACEs) among young adults in Iraq as well as to estimate the association between ACEs and depression. Methods A convenience sample of young adults of 18–20 years was chosen from centre and west of Iraq, mainly from universities. The adverse childhood experiences were measured by Adverse Childhood Experiences Questionnaire. A depression scale was derived from the Depression, Anxiety and Stress Scales (DASS). Statistical tests: chi square was used to measure the association between adverse childhood experiences and other variables like gender and depression. Odds ratios were computed to estimate the risk for depression. A P value of less than 0.05 was considered statistically significant. Results The total number of participants was 401, 38.9% of the subjects were men, while 61.1% were women. The mean age of the participants was 18.88 ± 0.745. The results revealed that the most common forms of ACEs among the subjects were physical neglect (19.8%) and emotional neglect (19.2%) followed by physical abuse (17.21%) while sexual abuse was 7.52%. There was statistically significant association between most forms of adverse childhood experiences especially emotional abuse, emotional neglect, physical abuse and physical neglect with depression. Conclusion ACEs are not uncommon among young adults in Iraq and are associated with depression in adulthood. National programmes to support mental health rehabilitation might be necessary to reduce the effect of ACEs among Iraqi people, especially for adolescents and young adults.

scholarly journals Effect of differently worded messages about alcohol on intent to breastfeed among university women in South Korea

2019 ◽  
Vol 10 (2) ◽  
pp. 27-39
Author(s):  
Ted H Greiner ◽  
Igor Z Zubrzycki ◽  
Boseul Jegal ◽  
Sang-Sun Lee
Keyword(s):  
Alcohol Consumption ◽  
Alcohol Use ◽  
Heavy Drinking ◽  
The Body ◽  
Convenience Sample ◽  
University Women ◽  
Duration Of Breastfeeding ◽  
Different Cultures ◽  
The Impact ◽  
Intention To Breastfeed

Background: There is concern that advice not to drink alcohol could discourage the initiation and particularly shorten the duration of breastfeeding. However, little research has explored the impact of variously worded messages about drinking while breastfeeding on women’s intentions to drink or to breastfeed. Methods: We haphazardly allocated a convenience sample of nulliparous (>95%) Korean female university students to be exposed to three differently worded messages on alcohol use during breastfeeding in the body of a questionnaire. Translated to English, they were as follows: Liberal: “Breastfeeding is compatible with moderate but not heavy drinking of alcohol.” Moderate: “You can use alcohol while breastfeeding, but only on rare occasions and only 1-2 drinks at a time. Too much alcohol can harm the breastfeeding process. After each drink, you should wait 2 hours before breastfeeding to keep the child from being affected.” Strict: “You should never use alcohol while you are breastfeeding.” Results: Most of the 280 valid responses expressed an intention to breastfeed. Over 90% of sampled women drank alcohol currently; 91% of them intended to reduce consumption during breastfeeding. How strictly messages were worded did not affect intention to drink during breastfeeding. Neither strict nor liberal messages reduced intention to drink alcohol while breastfeeding. The strict message clearly told the students what to do, whereas the moderate and liberal messages left choices up to them. Receiving these messages that required women to decide for themselves reduced the women’s intention to breastfeed (p<0.001). Conclusions: In this sample of largely nulliparous university women, a more strictly worded message regarding alcohol use during breastfeeding did not reduce breastfeeding intentions. Messages that left decisions up to the women did. The risk of harm associated with alcohol consumption during breastfeeding should we weighed against the risk that raising concerns about alcohol consumption might reduce the initiation or duration of breastfeeding. Research is needed to test such messages in different cultures and to follow up after delivery to see if indeed expressed intent correlates with actual practices. Until then, messages regarding breastfeeding and alcohol are likely to continue to be based only on the unexamined assumptions as to whether cautions about alcohol will affect women’s breastfeeding practices.

Impact of childhood trauma on co-morbidity among alcohol dependent patients: Controlled study

2017 ◽  
Vol 41 (S1) ◽  
pp. s864-s864
Author(s):  
D. Gulec Oyekcin ◽  
A. Gurgen
Keyword(s):  
Alcohol Use ◽  
Psychiatric Disorders ◽  
Childhood Trauma ◽  
Emotional Abuse ◽  
Alcohol Use Disorders ◽  
Controlled Study ◽  
Treatment Seeking ◽  
Co Morbidity ◽  
Physical Neglect ◽  
Alcohol Dependent

IntroductionChildhood trauma has been found to be prevalent in treatment-seeking alcoholics.ObjectivesWe aimed to investigate the childhood trauma prevalence among alcohol dependent patients and the prevalence of psychiatric co-morbidity.MethodsA total of 61 participants were assessed; 35 treatment-seeking alcohol dependent patients and 26 age-gender matched controls in the addiction division of psychiatry department of Çanakkale Onsekiz Mart University. After describing the study and obtaining informed consent, participants were assessed with demographic questionnaires, followed by the structured clinical interview for the DSM-IV-TR and childhood trauma questionnaire (CTQ-28).ResultThe 91.4% of the patients were male, mean age was 42.03 ± 12.9. The overall prevalence of CTE of the alcohol dependent patients was (88.6%) higher than the control (42.3%) group. Respectively the prevalence of physical neglect was 80%, emotional neglect 74.3%, emotional abuse was 51.4%, physical abuse 40% and sexual abuse 28.6%. For psychiatric disorders 96.8% of the alcohol dependent patients with childhood trauma reported any of the psychiatric disorders, 64.5% ever having a mood disorder with 25.8% ever having any anxiety disorders, and 16.1% ever having attention and hyperactivity disorder. The most common psychiatric co-morbidity was found to be as depression (58.1%).ConclusionsIn conclusion alcohol use disorders are thought to be associated with childhood trauma. Patients with alcohol use disorders are exposed to have more childhood trauma. Childhood trauma is associated with psychiatric co-morbidity especially depression. We have to ask for childhood trauma in alcohol dependent patients with psychiatric co-morbidity.Disclosure of interestThe authors have not supplied their declaration of competing interest.

Childhood Abuse, Parenting and Postpartum Depression

1998 ◽  
Vol 32 (4) ◽  
pp. 479-487 ◽  
Author(s):  
Anne Buist
Keyword(s):  
Physical Abuse ◽  
Childhood Abuse ◽  
Emotional Abuse ◽  
Sexually Abused ◽  
Depressive Disorders ◽  
Severe Depression ◽  
Negative Effects ◽  
History Of Childhood ◽  
Lengths Of Stay ◽  
History Of

Objective: While the potential negative effects on children of maternal depression has been documented, the influence of a maternal history of childhood abuse on child development is unclear. This study, the first stage of a 3–year follow-up study, looks at childhood abuse in women with depression in the postpartum period. Method: Fifty-six women admitted with postpartum depressive disorders were assessed with respect to their wellbeing, relationships and infant interaction. Twenty-eight women had a history of sexual abuse before the age of 16, nine physical/ emotional abuse and 19 had no history of abuse. Results: The mother-infant relationship was seen to be impaired in the sexually abused group (p = 0.007). The significance increased when all abused women were compared to controls (p = 0.001). In addition, abuse was associated with more severe depression on the Beck Depression Inventory (p = 0.046), and a trend to higher anxiety and longer lengths of stay (p = 0.05 for physical abuse). Partners rated themselves as being more skilled and confident parents. Conclusions: The effect of childhood abuse was indistinguishable between emotional and physical abuse in postpartum depressed women. The most significant effect was a deleterious one on the mother-infant relationship in those women with a history of abuse.

scholarly journals Cloninger's temperament dimensions and longitudinal alcohol use in early mid-life: A Northern Finland birth cohort 1966 study

2016 ◽  
Vol 33 (S1) ◽  
pp. S118-S118
Author(s):  
D. Vladimirov ◽  
S. Niemelä ◽  
J. Auvinen ◽  
M. Timonen ◽  
S. Keinänen-Kiukaanniemi ◽  
...  
Keyword(s):  
Alcohol Consumption ◽  
Alcohol Use ◽  
Birth Cohort ◽  
Heavy Drinking ◽  
Novelty Seeking ◽  
Multinomial Regression ◽  
Time Points ◽  
Problematic Alcohol ◽  
Competing Interest ◽  
Problematic Alcohol Use

BackgroundLongitudinal studies on how temperament is related to alcohol use in general population are scarce.ObjectivesFinding relations with temperament and problematic alcohol use using prospective birth cohort data.AimsTo investigate trends in self-reported alcohol consumption in adulthood.MethodsIn the Northern Finland Birth Cohort 1966 (n = 5247), alcohol use was studied with questionnaires at ages 31 and 46. Participants were classified into abstainers, bingers, heavy drinkers, steady drinkers, increasers or reducers based on the change in consumption (g/day). Cloninger's TCI-scores were calculated for each group. Multinomial regression analysis was conducted with TCI-scores as factors influencing the change in alcohol consumption.ResultsHigh novelty seeking was associated with increased consumption, binging and heavy drinking among both sexes at both time points (P < 0.01). Lower persistence was associated with increased consumption at both time points among men and among women at age 46. Baseline novelty seeking predicted both increasing (OR 1.1; 95% CI: 1.0–1.1) and reducing (1.1; 1.0–1.1) for men and for women also increasing (1.1; 1.0–1.1) and reducing (1.1; 1.0–1.1), but when adjusted with baseline alcohol use novelty seeking only predicted increasing for men (1.0; 1.0–1.1).ConclusionsHigh novelty seeking and low persistence are associated with problematic alcohol use among middle-aged Northern Finns. Gender differences in predictors existed: novelty seeking predicted increase only for men in the adjusted model. Temperament scores do not seem to affect strongly changes in alcohol use.Disclosure of interestThe authors have not supplied their declaration of competing interest.

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