scholarly journals Lockdown effect on COVID-19 incidence and death: Iran experience

Author(s):  
Sajad Delavari ◽  
Zahra Jamali ◽  
Mohsen Bayati

Abstract Background: Countries are trying several policy options for decreasing the incidence and burden of the COVID-19. One of these strategies is a lockdown, complete closure, to reduce the risk of distributing disease via social interactions. This study aimed to analyze the effect of a three-week lockdown on the mortality and morbidity of the COVID-19 in Iran. Methods: Official daily data on COVID-19 incidence and death reported on the COVID-19 by the World Health Organization (WHO) were extracted from September 1, 2020, to January 14, 2021. Data were analyzed using interrupted time series analysis via STATA 14 software. Results: Lockdown resulted in a significant reduction in the daily death from Covid-19 in the short-term (β=-139, P<0.01) and in the long-term (β=-12, P<0.01). Moreover, lockdown in the short-term insignificantly (β=-21.58, P=0.969), and in the long-term significantly (β=-317.31, P<0.01) reduced the Covid-19 daily incidence. Discussion: The results showed that the lockdown has a significant effect on incidence and death numbers. Therefore, it could be a suitable short-term strategy for controlling the COVID-19 outbreak. On the other hand, its negative effects on households and businesses should be considered.

2020 ◽  
Vol 1 (2) ◽  
pp. 16-24
Author(s):  
Elena S. Akarachkova ◽  
◽  
Anton A. Beliaev ◽  
Dmitrii V. Blinov ◽  
Evgenii V. Bugorskii ◽  
...  

World Health Organization declared COVID-19 outbreak a pandemic on March 11, 2020. Fear of illness, self-isolation/quarantine, and reduced quality of life dramatically increased the prevalence of stress-related disorders in the population. Therefore, it is necessary to implement the preventive health-care measures aimed at short-term and long-term COVID-19 pandemic consequences reduction and promotion of social stability.


2020 ◽  
Author(s):  
Yumi Suzuki ◽  
Motoko Morino ◽  
Ichizo Morita ◽  
Shigenori Yamamoto

Abstract Background:A World Health Organization (WHO) guideline-based multimodal hand hygiene (HH) initiative consisting of the 5 Components, the 5 Steps, and the HH Self-Assessment Framework (HHSAF) was introduced hospital-wide to a nonteaching Japanese hospital for 5 years. The objective of this study was to assess the effect of this initiative in terms of changes in alcohol-based hand rub (ABHR) consumption and HHSAF score.Methods:The consumption of monthly hospital-wide ABHR was calculated as ml per patient day (PD). The change in ABHR consumption was analysed by an interrupted time series analysis, with a preintervention period of 36 months and an intervention period of 60 months. The correlation between annual ABHR consumption and the HHSAF score was estimated using Pearson’s correlation coefficients.Results:A statistically significant increase was found in the monthly ABHR consumption (change in slope: + 0.479 ml/PD, p < 0.01). Annual ABHR consumption was strongly correlated with the annual HHSAF score (r = 0.971, p < 0.01).Conclusions:A 5-year, 5-step, WHO-based HH initiative significantly increased ABHR consumption. Our study suggested that the HHSAF score can be a good process measure to improve HH in a single facility, as ABHR consumption increased with the HHSAF score.


2020 ◽  
Author(s):  
Yumi Suzuki ◽  
Motoko Morino ◽  
Ichizo Morita ◽  
Shigenori Yamamoto

Abstract Background: A World Health Organization (WHO) guideline-based multimodal hand hygiene (HH) initiative was introduced hospital-wide to a nonteaching Japanese hospital for 5 years. The objective of this study was to assess the effect of this initiative in terms of changes in alcohol-based hand rub (ABHR) consumption and the Hand Hygiene Self-Assessment Framework (HHSAF) score.Methods: The consumption of monthly hospital-wide ABHR was calculated in L per 1000 patient days (PDs). The change in ABHR consumption was analysed by an interrupted time series analysis with a pre-implementation period of 36 months and an implementation period of 60 months. The correlation between annual ABHR consumption and the HHSAF score was estimated using Pearson’s correlation coefficients.Results: The annual ABHR consumption was 4.0 (L/1000 PDs) to 4.4 in the pre-implementation period and 10.4 to 34.4 in the implementation period. The HHSAF score was 117.5 (out of 500) in the pre-implementation period and 267.5 to 445 in the implementation period. A statistically significant increase in the monthly ABHR consumption (change in slope: + 0.479 L/1000 PDs, p < 0.01) was observed with the implementation of the initiative. Annual ABHR consumption was strongly correlated with the annual HHSAF score (r = 0.971, p < 0.01).Conclusions: A 5-year WHO-based HH initiative significantly increased ABHR consumption. Our study suggested that the HHSAF assessment can be a good process measure to improve HH in a single facility, as ABHR consumption increased with the HHSAF score.


Author(s):  
Masoumeh Rahmatinia ◽  
Anooshiravan Mohseni Bandpey ◽  
Abbas Shahsavani ◽  
Mostafa Hadei ◽  
Ahmad Jonidi Jafari ◽  
...  

Introduction: The novel coronavirus disease 2019, namely COVID-19, has been known as a global pandemic by the World Health Organization (WHO). To prevent of COVID-19 spread, most countries including Iran have implemented many preventive measures. This study aimed to evaluate the effect of implementation (Phase-01)/non- implementation (Phase-02) of the traffic plan on confirmed cases, suspected cases, and mortality cases by COVID-19 as well as on air quality in Tehran. Materials and methods: Daily data of confirmed COVID-19 cases, suspected COVID-19 cases, mortality COVID-19 cases, air pollutants concentration and meteorological variables were obtained from 26 February, 2020 to 5August, 2020 in Tehran megacity and data were compared during the period’s implementation /non-implementation of traffic plan in Tehran. Results: Our results showed that the non-implementation of traffic plan has been effective in reducing the number of daily confirmed cases, suspected cases and mortality by COVID-19. Also, the average concentration of PM10, PM2.5, NO2 , O3 , SO2 and CO have reduced significantly during nonimplementation traffic plan phase. Conclusion: Our findings indicate that there is a significant association between non-implementation traffic plan and reduce risk of COVID-19 infection.


PLoS Medicine ◽  
2020 ◽  
Vol 17 (11) ◽  
pp. e1003269
Author(s):  
David Pell ◽  
Tarra L. Penney ◽  
Oliver Mytton ◽  
Adam Briggs ◽  
Steven Cummins ◽  
...  

Background Sugar-sweetened beverage (SSB) consumption is positively associated with obesity, type 2 diabetes, and cardiovascular disease. The World Health Organization recommends that member states implement effective taxes on SSBs to reduce consumption. The United Kingdom Soft Drinks Industry Levy (SDIL) is a two-tiered tax, announced in March 2016 and implemented in April 2018. Drinks with ≥8 g of sugar per 100 ml (higher levy tier) are taxed at £0.24 per litre, drinks with ≥5 to <8 g of sugar per 100 ml (lower levy tier) are taxed at £0.18 per litre, and drinks with <5 g sugar per 100 ml (no levy) are not taxed. Milk-based drinks, pure fruit juices, drinks sold as powder, and drinks with >1.2% alcohol by volume are exempt. We aimed to determine if the announcement of the SDIL was associated with anticipatory changes in purchases of soft drinks prior to implementation of the SDIL in April 2018. We explored differences in the volume of and amount of sugar in household purchases of drinks in each levy tier at 2 years post announcement. Methods and findings We used controlled interrupted time series to compare observed changes associated with the announcement of the SDIL to the counterfactual scenario of no announcement. We used data from Kantar Worldpanel, a commercial household purchasing panel with approximately 30,000 British members that includes linked nutritional data on purchases. We conducted separate analyses for drinks liable for the SDIL in the higher, lower, and no-levy tiers controlling with household purchase volumes of toiletries. At 2 years post announcement, there was no difference in volume of or sugar from purchases of higher-levy-tier drinks compared to the counterfactual of no announcement. In contrast, a reversal of the existing upward trend in volume (ml) of and amount of sugar (g) in purchases of lower-levy-tier drinks was seen. These changes led to a −96.1 ml (95% confidence interval [CI] −144.2 to −48.0) reduction in volume and −6.4 g (95% CI −9.8 to −3.1) reduction in sugar purchased in these drinks per household per week. There was a reversal of the existing downward trend in the amount of sugar in household purchases of the no-levy drinks but no change in volume purchased. At 2 years post announcement, these changes led to a 6.1 g (95% CI 3.9–8.2) increase in sugar purchased in these drinks per household per week. There was no evidence that volume of or amount of sugar in purchases of all drinks combined was different from the counterfactual. This is an observational study, and changes other than the SDIL may have been responsible for the results reported. Purchases consumed outside of the home were not accounted for. Conclusions The announcement of the UK SDIL was associated with reductions in volume and sugar purchased in lower-levy-tier drinks before implementation. These were offset by increases in sugar purchased from no-levy drinks. These findings may reflect reformulation of drinks from the lower levy to no-levy tier with removal of some but not all sugar, alongside changes in consumer attitudes and beliefs. Trial registration ISRCTN Registry ISRCTN18042742.


2021 ◽  
pp. medethics-2021-107763
Author(s):  
Nancy S Jecker ◽  
Derrick K S Au

Since the World Health Organization (WHO) first declared the novel coronavirus a pandemic, diverse strategies have emerged to address it. This paper focuses on two leading strategies, elimination and mitigation, and examines their ethical basis. Elimination or ‘Zero-COVID’ dominates policies in Pacific Rim societies. It sets as a goal zero deaths and seeks to contain transmission using stringent short-term lockdowns, followed by strict find, test, trace and isolate methods. Mitigation, which dominates in the US and most European nations, sets targets for community transmission and lifts restrictions once targets are met. This approach takes calculated risks and regards a certain amount of disease and death as ethically justified. Section I examines different societal responses to risk that underlie these different policy approaches. Section II focuses on ethical arguments favouring Zero-COVID and raises health equity objections. Section III proposes a long-term strategy that balances the twin goals of promoting population health and health equity.


2001 ◽  
Vol 178 (1) ◽  
pp. 71-75 ◽  
Author(s):  
Ramin Mojtabai ◽  
Ezra Susser ◽  
Vijoy K. Varma ◽  
Savita Malhotra ◽  
Surendra K. Mattoo ◽  
...  

BackgroundThe short-term course of schizophrenia is reported to be better in some developing country settings. The long-term course in such settings, however, has rarely been studied.AimsTo examine the long-term course and mortality of schizophrenia in patients with a poor 2-year course.MethodThe report is based on two incidence cohorts of first-contact patients in urban and rural Chandigarh, India, originally recruited for the World Health Organization Determinants of Outcome of Severe Mental Disorders study. Patients were assessed using standardised instruments at 2- and 15-year follow-ups.ResultsNinety-two per cent of the patients with a poor 2-year course had a poor long-term course and 47% died – a nine times higher mortality rate than among patients with other 2-year course types.ConclusionsIn this developing country setting, a poor 2-year course was strongly predictive of poor prognosis and high mortality, raising questions about the adequacy of care for such patients.


The COVID-19 pandemic had a global impact since it was first discovered in late 2019, in Wuhan, China. According to the World Health Organization (WHO), COVID-19 has affected over 179 million people and killed approximately 3.9 million people in more than 200 countries across the globe (WHO,2021). This outbreak has not only affected people’s lives but also disrupted global supply chains. It has shown significant effects on businesses, consumers, and the global economy. Fear of the virus has led to many companies scrambling to respond regarding employees’ job security, ensuring supply security, risk mitigation strategy, and addressing market uncertainties that are driving down demand. Broadly, the objective of this article is to highlight issues faced by the upstream palm oil supply chain actors during this pandemic. Based on the problem, the study concluded that some forms of actions (short-term & long-term) have been proposed to ensure an agile palm oil supply chain.


2022 ◽  
Author(s):  
Brianna Belsky ◽  
Quentin Minson

Abstract Background. While various strategies for antibiotic restrictions have been validated, their impacts are not well described in smaller, non-teaching facilities. Fluoroquinolones are an appropriate target for restriction based on their propensity for overuse and potential for causing “collateral damage.” Aim. Evaluate the impact of a multifaceted approach to decreasing fluoroquinolone use on fluoroquinolones and alternative antibiotics at a smaller, non-teaching facility. Method. Retrospective, interrupted time series analysis conducted at a single 288-bed, tertiary, non-teaching hospital with 71 adult ICU beds comparing antibiotic consumption measured monthly by defined daily doses per 1000 adjusted patient days (DDD/1000 APD) prior to intervention (January 2011 to August 2014) to short-term (October 2014 to December 2015) and long-term (January 2018 to December 2019) periods following intervention. Results. An increase in downward trends of fluoroquinolone use was observed from prior to intervention (-0.49 DDD/1000 APD) to the short-term period (-1.13 DDD/1000 APD) and to a greater extent in the long-term period following the intervention (-1.32 DDD/1000 APD). Fluoroquinolone consumption decreased from 100.20 DDD/1000 APD in August 2014 to 73.96 DDD/1000 APD in the short-term and 14.89 DDD/1000 APD in the long-term intervention period. Levofloxacin susceptibility for Pseudomonas aeruginosa increased from 61% in 2014 to 83% in 2018. No deleterious effects on Pseudomonas aeruginosa susceptibilities were observed for alternative antibiotics. Conclusion. A multifaceted approach to decreasing fluoroquinolone use at a smaller, tertiary, non-teaching hospital led to a sustained decrease in consumption and a substantial increase in levofloxacin susceptibility to Pseudomonas aeruginosa.


Author(s):  
Ferdy Royland Marpaung ◽  
Trieva Verawaty Butarbutar ◽  
Sidarti Soehita

World Health Organization (WHO) and Stages of Reproductive Aging Workshop (STRAW) define menopause as a permanent end point of menstrual cycle that occurs naturally or by induction of surgical procedure, chemotherapy, or radiation. Clinically, menopause involved women over 40 or 50 years old. Approximately, fifty million women in the world is experiencing menopause annually. The etiology of menopause is classified into physiologic and non-physiologic. Pathophysiology of menopause includes decline of ovary function in menopause, response to loss of ovarian feedback mechanism, decline of hypothalamus and pituitary function. Endocrine changes in menopause lead to alteration of gonadotropin secretion cycle patterns, changes in steroid and peptide hormones through monophasic patterns to increase gonadotropin, decrease of estrogen, progesterone and inhibin. Clinical symptoms of menopause or estrogen deficiency syndrome classified into short term clinical symptoms and long term clinical symptoms. Hormonal examination in menopause consist of Follicular Stimulating Hormone (FSH), Anti-Mullerian Hormone (AMH), Luteinizing Hormone (LH), Inhibin B and Estradiol. The important of time to examine the hormones should be considered carefully.


Sign in / Sign up

Export Citation Format

Share Document