scholarly journals Mortality and long-term course in schizophrenia with a poor 2-year course

2001 ◽  
Vol 178 (1) ◽  
pp. 71-75 ◽  
Author(s):  
Ramin Mojtabai ◽  
Ezra Susser ◽  
Vijoy K. Varma ◽  
Savita Malhotra ◽  
Surendra K. Mattoo ◽  
...  
Keyword(s):  
Mortality Rate ◽  
Developing Country ◽  
Poor Prognosis ◽  
World Health ◽  
Severe Mental Disorders ◽  
Short Term ◽  
The World ◽  
Health Organization ◽  
First Contact

BackgroundThe short-term course of schizophrenia is reported to be better in some developing country settings. The long-term course in such settings, however, has rarely been studied.AimsTo examine the long-term course and mortality of schizophrenia in patients with a poor 2-year course.MethodThe report is based on two incidence cohorts of first-contact patients in urban and rural Chandigarh, India, originally recruited for the World Health Organization Determinants of Outcome of Severe Mental Disorders study. Patients were assessed using standardised instruments at 2- and 15-year follow-ups.ResultsNinety-two per cent of the patients with a poor 2-year course had a poor long-term course and 47% died – a nine times higher mortality rate than among patients with other 2-year course types.ConclusionsIn this developing country setting, a poor 2-year course was strongly predictive of poor prognosis and high mortality, raising questions about the adequacy of care for such patients.

Gynecologic Cancer InterGroup (GCIG) Consensus Review for Ovarian Small Cell Cancers

2014 ◽  
Vol 24 (Supp 3) ◽  
pp. S30-S34 ◽  
Author(s):  
Nicholas Simon Reed ◽  
Patricia Pautier ◽  
Elizabeth Åvall-Lundqvist ◽  
Chel-Hun Choi ◽  
Andreas du Bois ◽  
...  
Keyword(s):  
Poor Prognosis ◽  
Gynecologic Cancer ◽  
Small Cell ◽  
World Health ◽  
Ovarian Cancers ◽  
The World ◽  
Aggressive Tumors ◽  
Health Organization ◽  
Long Term Survivors

AbstractSmall cell carcinomas of the ovary are uncommon and account for less than 1% of ovarian cancers. They were first recognized in 1979, and a number of reports appeared during the next 2 decades. They are highly aggressive tumors and usually carry a poor prognosis, although this may reflect that most are diagnosed at advanced stage; however, those diagnosed as stage 1A have only 30% to 40% of long-term survivors. More reports followed extending our experience in the diagnosis and management of these rare cancers. The classification is described below and shown in Table 1, but a revision is expected to be published from the World Health Organization in 2014.

scholarly journals Psychometric validation of the Chinese version of the PaArticular Scales among elderly residents in long-term care facilities with joint contractures

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Yi-chang Chen ◽  
Keh-chung Lin ◽  
Chen-Jung Chen ◽  
Shu-Hui Yeh ◽  
Ay-Woan Pan ◽  
...  
Keyword(s):  
World Health Organization ◽  
Long Term Care ◽  
Chinese Version ◽  
World Health ◽  
Term Care ◽  
Joint Contractures ◽  
The World ◽  
Health Organization

Abstract Background Joint contractures, which affect activity, participation, and quality of life, are common complications of neurological conditions among elderly residents in long-term care facilities. This study examined the reliability and validity of the Chinese version of the PaArticular Scales in a population with joint contractures. Methods A cross-sectional study design was used. The sample included elderly residents older than 64 years with joint contractures in an important joint who had lived at one of 12 long-term care facilities in Taiwan for more than 6 months (N = 243). The Chinese version of the PaArticular Scales for joint contractures was generated from the English version through five stages: translation, review, back-translation, review by a panel of specialists, and a pretest. Test-retest reliability, internal consistency reliability, construct validity, and criterion validity were evaluated, and the results were compared with those for the World Health Organization Quality of Life scale and the World Health Organization Disability Assessment Schedule. Results The Chinese version of the PaArticular Scales had excellent reliability, with a Cronbach α coefficient of 0.975 (mean score, 28.98; standard deviation, 17.34). An exploratory factor analysis showed three factors and one factor with an eigenvalue > 1 that explained 75.176 and 62.83 % of the total variance in the Activity subscale and Participation subscale, respectively. The subscale-to-total scale correlation analysis showed Pearson correlation coefficients of 0.881 for the Activity subscale and 0.843 for the Participation subscale. Pearson’s product-moment correlation revealed that the correlation coefficient (r) between the Chinese version of the PaArticular Scales and the World Health Organization Disability Assessment Schedule was 0.770, whereas that for the World Health Organization Quality of Life scale was − 0.553; these values were interpreted as large coefficients. Conclusions The underlying theoretical model of the Chinese version of the PaArticular Scales functions well in Taiwan and has acceptable levels of reliability and validity. However, the Chinese version must be further tested for applicability and generalizability in future studies, preferably with a larger sample and in different clinical domains.

scholarly journals Coronavirus Pandemic: Coping with the Psychological Outcomes, Mental Changes, and the “New Normal” During and After COVID-19

2020 ◽  
pp. 07-19
Author(s):  
Hiba Takieddine ◽  
Samaa AL Tabbah
Keyword(s):  
Healthcare Providers ◽  
Well Being ◽  
World Health ◽  
Vulnerable Groups ◽  
Public Health Response ◽  
New Normal ◽  
The World ◽  
Health Organization ◽  
The Impact

Coronavirus disease 2019 (COVID-19) is a highly infectious disease that has rapidly swept across the world, inducing a considerable degree of fear, worry and concern in the population at large and among certain groups in particular, such as older adults, healthcare providers and people with underlying health conditions. Authorities around the world tried to prevent the virus spread by imposing social distancing measures, quarantining citizens and isolating infected persons. Apart from its physical impact, COVID-19 pandemic has brought numerous changes to people’s lives. It changed daily routines, caused worldwide economic crisis, increased unemployment, and placed people under emotional and financial pressures. It affected people psychologically and mentally especially in terms of emotions and cognition. During the acute crisis, everyone to varying degrees experienced fear of infection, somatic concerns, worries about the pandemic’s consequences, loneliness, depression, stress, as well as increased alcohol and drug use. As part of its public health response, the World Health Organization (WHO) has worked with partners to develop a set of new guidelines and messages that can be used to prevent, manage, and support mental and psychological well-being in different vulnerable target groups during the outbreak. Whether people like it or not, the psychological sequela of this pandemic will emerge and persist for months and years to come leading to long-term consequences. New lifestyles and “New Normals” will surely emerge. The main purpose of this review is to summarize the impact of coronavirus pandemic on the psychological and mental health of people around the world especially vulnerable groups. It also presents the relevant intervention actions and recommendations to cope efficiently and effectively with the psychological short-term and long-term outcomes, mental changes, and the “New Normal” during and after COVID-19. Keywords: COVID-19; Coronavirus, Psychological; Mental; New Normal

scholarly journals Literature Review The Relationship Of Antenatal Class Towards Mothers’ Knowledge Of DangerousSign During Pregnancy

2021 ◽  
Vol 3 (2) ◽  
Author(s):  
Ayu Kurniati ◽  
Enny Fitriahadi
Keyword(s):  
Developing Countries ◽  
Mortality Rate ◽  
Literature Review ◽  
World Health ◽  
Live Births ◽  
Complication Risk ◽  
The World ◽  
Health Organization ◽  
Relationship Of ◽  
The Relationship

IN 2013, the World Health Organization, released data in the form of Maternal Mortality Rate (MMR) worldwide, and the number reached 289,000 per 100, 000 live births, which 99% of cases occurred in developing countries. Research aims to discover the relationship of antenatal class towards mothers’ knowledge of the dangerous sign during pregnancy. The result showed that there is a relationship of antenatal class towards mothers’ knowledge of dangerous sign during pregnancy, From this result, the researcher concludes that antenatal class could increase mothers’ knowledge of dangerous sign during pregnancy and may decrease the complication risk during the childbirth.

scholarly journals A review of post infectious pulmonary fibrosis in the era of COVID-19 and potential treatment options

2021 ◽  
Vol 9 (40) ◽  
pp. 37-46
Author(s):  
Medha Ghose ◽  
Maehali Patel
Keyword(s):  
Risk Factors ◽  
Pulmonary Fibrosis ◽  
Treatment Options ◽  
World Health ◽  
Potential Treatment ◽  
Pulmonary Injury ◽  
The World ◽  
Health Organization ◽  
Post Infectious

On March 11, 2020, the World Health Organization (WHO) released a statement characterizing COVID-19 as a pandemic that has, as of October 2020, caused almost 36 million confirmed global cases and over 1 million deaths. One of the long-term complications suggested by researchers is fibrosis. It has been hypothesized that the combination of ongoing pulmonary injury caused by COVID-19 and the inability to promptly repair damage results in interstitial matrix widening and eventual compression and destruction of alveoli and capillaries. Here we focus on pathogenesis, risk factors, different infectious causes of fibrosis along with COVID-19, and potential treatment options that might reduce its effects. Key words: COVID-19, pulmonary fibrosis, mechanism, treatment

scholarly journals COVID-19 pandemic. Effects of stress

2020 ◽  
Vol 1 (2) ◽  
pp. 16-24
Author(s):  
Elena S. Akarachkova ◽  
◽  
Anton A. Beliaev ◽  
Dmitrii V. Blinov ◽  
Evgenii V. Bugorskii ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Health Care ◽  
Preventive Health Care ◽  
Preventive Health ◽  
World Health ◽  
Social Stability ◽  
Short Term ◽  
Health Organization

World Health Organization declared COVID-19 outbreak a pandemic on March 11, 2020. Fear of illness, self-isolation/quarantine, and reduced quality of life dramatically increased the prevalence of stress-related disorders in the population. Therefore, it is necessary to implement the preventive health-care measures aimed at short-term and long-term COVID-19 pandemic consequences reduction and promotion of social stability.

scholarly journals "CHRONIC SORROW THEORY APPLICATION" TO OVERCOME THE FEELING OF LOSS DUE TO INFANT MORTALITY IN POST-PARTUM WOMEN

2019 ◽  
Vol 2 (1) ◽  
Author(s):  
Dedeh Sri Rahayu
Keyword(s):  
Mortality Rate ◽  
Infant Mortality ◽  
Assessment Tool ◽  
Post Partum ◽  
Infant Mortality Rate ◽  
World Health ◽  
Chronic Sorrow ◽  
The World ◽  
Theory Application ◽  
Health Organization

Data from the World Health Organization (WHO) in 2012 stated that 44% of infant deaths in the world occurred in the first 28 days of life (neonatal period). The research results of the Central Statistics Agency (CSA) in 2016 noted that the infant mortality rate (IMR) reached 25.5%, West Java Province was one of the contributors to the highest maternal mortality rate (MMR) and infant mortality rate (IMR). Infant mortality inside the womb or outside the womb triggers grief and deep sorrow that is at risk of progressive, repetitive and permanent in women. Nurses in the maternity area play an important role in overcoming the problem of loss through various approaches to either theory or intervention. The purpose of this study was to determine the application of chronic sorrow theory in post-partum women whose babies were dead at Sariningsih Hospital Bandung. Method: This research was qualitative research. Participants were 5 people selected using purposive sampling techniques. Data collection was done by interviewing using a guide from the Burke / Eakes Chronic Sorrow Assessment Tool. Results: It was identified that women's opinions about the causes of infant mortalities were planned (abortion) and unplanned. Participants had effective coping strategies in dealing with their loss such as social support, and spiritual beliefs for comfort. Conclusion: participants felt the effectiveness of the chronic sorrow theory to overcome infant loss.Keywords: chronic sorrow theory application, loss, post-partum women, Qualitative.

scholarly journals Beyond the List: Bioagent-Agnostic Signatures Could Enable a More Flexible and Resilient Biodefense Posture Than an Approach Based on Priority Agent Lists Alone

Pathogens ◽  
2021 ◽  
Vol 10 (11) ◽  
pp. 1497
Author(s):  
Owen P. Leiser ◽  
Errett C. Hobbs ◽  
Amy C. Sims ◽  
George W. Korch ◽  
Karen L. Taylor
Keyword(s):  
Research Community ◽  
Interdisciplinary Teams ◽  
World Health ◽  
Biological Warfare ◽  
The World ◽  
Health Organization ◽  
Data Analytic ◽  
Current List ◽  
Great Harm

As of 2021, the biothreat policy and research communities organize their efforts around lists of priority agents, which elides consideration of novel pathogens and biotoxins. For example, the Select Agents and Toxins list is composed of agents that historic biological warfare programs had weaponized or that have previously caused great harm during natural outbreaks. Similarly, lists of priority agents promulgated by the World Health Organization and the National Institute of Allergy and Infectious Diseases are composed of previously known pathogens and biotoxins. To fill this gap, we argue that the research/scientific and biodefense/biosecurity communities should categorize agents based on how they impact their hosts to augment current list-based paradigms. Specifically, we propose integrating the results of multi-omics studies to identify bioagent-agnostic signatures (BASs) of disease—namely, patterns of biomarkers that accurately and reproducibly predict the impacts of infection or intoxication without prior knowledge of the causative agent. Here, we highlight three pathways that investigators might exploit as sources of signals to construct BASs and their applicability to this framework. The research community will need to forge robust interdisciplinary teams to surmount substantial experimental, technical, and data analytic challenges that stand in the way of our long-term vision. However, if successful, our functionality-based BAS model could present a means to more effectively surveil for and treat known and novel agents alike.

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