The wounded roan: a contribution to the relation of hunting and trance in southern African rock art

Antiquity ◽  
2005 ◽  
Vol 79 (303) ◽  
pp. 5-18 ◽  
Author(s):  
J. Francis Thackeray
Keyword(s):  
Rock Art ◽  
Roan Antelope ◽  
Animal Skin ◽  
New Hypothesis

A 1934 photograph of a man dressed in an animal skin and a painting of three figures in a cave at Melikane, Lesotho led to a new hypothesis about the role of the roan antelope in both the economy and beliefs of early Africa. The author shows that not only art, but language too, may reach back to a time when the need for food first began to find expression in ritual.

Inflammation and Pruning May Inform Risk to Psychiatric Disorders. Lessons From Large Genetic Data

2017 ◽  
Vol 41 (S1) ◽  
pp. S56-S56
Author(s):  
C. Crisafulli
Keyword(s):  
Psychiatric Disorders ◽  
Molecular Mechanics ◽  
Association Studies ◽  
Molecular Pathway ◽  
Starting Point ◽  
Single Effect ◽  
Competing Interest ◽  
The Brain ◽  
New Hypothesis

BackgroundIt's known that psychiatric disorders are caused to either environmental and genetics factors. Through the years several hypotheses were tested and many genes were screened for association, resulting in a huge amount of data available for the scientific community. Despite that, the molecular mechanics behind psychiatric disorders remains largely unknown. Traditional association studies may be not enough to pinpoint the molecular underpinnings of psychiatric disorder. We tried to applying a methodology that investigates molecular-pathway-analysis that takes into account several genes per time, clustered in consistent molecular groups and may successfully capture the signal of a number of genetic variations with a small single effect on the disease. This approach might reveal more of the molecular basis of psychiatric disorders.Methodsi)We collected data on studies available in literature for the studied disorder (e.g. Schizophrenia, Bipolar Disorder);ii)We extracted a pool of genes that are likely involved with the disease;iii)We used these genes as starting point to map molecular cascades function-linked. The molecular cascades are then analyzed and pathways and sub-pathways, possibly involved with them, are identified and tested for association.Results/discussionWe obtained interesting results. In particular, signals of enrichment (association) were obtained multiple times on the molecular pathway associated with the pruning activity and inflammation. Molecular mechanics related to neuronal pruning were focused as a major and new hypothesis for the pathophysiology of psychiatric disorders and the role of inflammatory events has been extensively investigated in psychiatry. intersting, inflammatory mechanics in the brain may also play a role in neuronal pruning during the early development of CNS.Disclosure of interestThe author has not supplied his declaration of competing interest.

Herod on the Rise

2021 ◽  
pp. 25-50
Author(s):  
Kimberley Czajkowski ◽  
Eckhardt Benedikt
Keyword(s):  
Universal History ◽  
New Hypothesis

This chapter covers Herod’s rise to kingship. It seeks to embed the ‘rising star narrative’ that we find in BJ 1 and AJ 14 into Nicolaus’ historical framework as far as it can be reconstructed from the fragments. This leads to a new hypothesis on the role of Herod’s Idumean origins in Nicolaus’ narrative. The chapter ultimately shows how Nicolaus’ portrait of the young Herod connected timeless patterns of universal history with the specific conditions created by Rome’s rise to universal power, and thus had a special appeal to an Augustan readership.

scholarly journals Demonstration, extension, and refinement of the re-proposed notion of design abduction

2020 ◽  
Vol 34 (2) ◽  
pp. 286-297
Author(s):  
Lauri Koskela ◽  
Ehud Kroll
Keyword(s):  
Philosophy Of Science ◽  
Retrospective Case ◽  
Model Based ◽  
Design Reasoning ◽  
Retrospective Case Study ◽  
New Hypothesis

AbstractThe original ideas on design abduction, inspired by treatments in philosophy of science, had a narrow conception on how novelty emerges in design, when looked at in terms of logic. The authors have previously presented a re-proposed notion of abduction in design, taking the differences between science and design into account. Now, in this article, the invention of the airplane by the Wright brothers is analyzed as a retrospective case study. Key parts of the re-proposed notion of design abduction are demonstrated, and two new types of design abduction are identified, namely strategic abduction and dynamic abduction. Perhaps even more importantly, a new hypothesis on the cognitive basis of design abduction is reached. While the importance of model-based abduction (and reasoning) is confirmed, the case also pinpoints the central role of verbalization and discussion in supporting design reasoning in general and especially abduction. All in all, it seems that an improved understanding of design abduction and its cognitive basis would be instrumental in promoting more effective and efficient designing.

scholarly journals The role of season in the epidemiology of influenza

1981 ◽  
Vol 86 (1) ◽  
pp. 35-47 ◽  
Author(s):  
R. E. Hope-Simpson
Keyword(s):  
Solar Radiation ◽  
Influenza A ◽  
Small Population ◽  
World Health ◽  
Small Community ◽  
Seasonal Characteristics ◽  
Health Organization ◽  
Influenza Outbreaks ◽  
New Hypothesis

SUMMARYFour types of observations have been used to illustrate the seasonal characteristics of epidemic influenza: (1) The experience of a small population during 28 consecutive years, 1946–74, (2) world influenza outbreaks 1964–75 reported to the World Health Organization, (3) the experience of two widely separated localities at about the same latitude, 1969–74, and (4) the experience of two places at latitudes 30° + on opposite sides of the Equator, 1968–74.The following tendencies are shown. (1) Outbreaks of influenza even in the small community came at approximately the same season almost every year. (2) Outbreaks are globally ubiquitous and epidemic loci move smoothly to and fro across the surface of the earth almost every year in a sinuous curve that runs parallel with the ‘midsummer’ curve of vertical solar radiation, but lags about six months behind it. Such findings exclude the mediation of seasonal control by any agencies of local distribution, and suggest a direct effect of variations in some component of solar radiation on virus or human host. (3) Antigenic variations in influenza A virus tended to have the same seasonal characteristics as epidemicity. This suggests that epidemicity and virus variation are two facets of one seasonally controlled process.None of these seasonal characteristics can be explained by the current concept of influenzal epidemiology. A new hypothesis recently proposed and recapitulated in the Appendix offers a possible explanation. The primary agency mediating seasonal control remains unidentified.

Rock art as a source of the history of prehistory (An account to promote the understanding of prehistoric rock art)

Abgadiyat ◽  
2009 ◽  
Vol 4 (1) ◽  
pp. 11-35
Author(s):  
Hamdi Abbas Ahmed Abd-EI-Moniem
Keyword(s):  
Material Culture ◽  
Rock Art ◽  
Archaeological Remains ◽  
Archaeological Material ◽  
The Third ◽  
History Of ◽  
Definition Of ◽  
Source Of Information ◽  
Remote Past

Abstract Some may believe that the history of mankind begins with the appearance of writing only a few several thousands of years ago (cf. 4000-3000 BCE). Our history, however, extends beyond that date millions of years. The history of mankind, indeed, is deeply rooted in the remote past which is called 'prehistory'. With the lacking of any form of writing, this 'prehistoric' period can be examined directly solely by recourse to the study of archaeological remains. The purpose of this account is to introduce rock art to the readers and show the significant role of this sort of archaeological material in studying the history of mankind before the appearance of written records. The current work, therefore, is divided into three main sections: the first deals with definition of rock art and its nature; the second section is devoted to showing the significance of this aspect of material culture in exploring a long and mysterious period of the early history of man characterized by the complete absence of written records or historical documents; the third and last section, which is a vital and integral part of this work, comprises an explanatory pictorial record to promote the understanding of prehistoric rock art as a source of information needed for writing the history of prehistory.

scholarly journals Occurrence of Malassezia Spp. on Healthy Human Skin

2019 ◽  
Vol 63 (4) ◽  
pp. 54-59
Author(s):  
Z. Malinovská ◽  
E. Čonková ◽  
P. Váczi ◽  
M. Harčárová ◽  
E. Böhmová
Keyword(s):  
Normal Skin ◽  
Seborrheic Dermatitis ◽  
The Elderly ◽  
Host Immune System ◽  
Healthy Human ◽  
Humoral Immune ◽  
Clinically Normal ◽  
Malassezia Spp ◽  
Animal Skin

Abstract The genus Malassezia currently includes seventeen species that have been isolated from healthy and diseased human and other animal skin. Malassezia are implicated in a range of cutaneous diseases in humans: pityriasis versicolor, atopic or seborrheic dermatitis, dandruff, folliculitis and psoriasis. The outbreak of the disease depends on the interaction between the host immune system and Malassezia species. Malassezia stimulates both the cellular and humoral immune response in humans. Although Malassezia species have been associated with various dermatological diseases in people, the detailed pathological role of Malassezia remains obscured. Malassezia yeasts require lipids for their growth and therefore to a greater extent they colonize the sites with more sebaceous glands. The ecosystem on skin is complex and its balance depends on several factors. The aim of this study was to determine the presence of Malassezia yeasts in clinically normal skin of 42 healthy, randomly selected individuals of different ages. In the group of people examined, up to 30 persons (71.4 %) represented by children, adults and the elderly were positive to Malassezia yeasts. It has been shown that the back is an area with a higher incidence (66.7 %) of observed yeast compared to the head (40.5 %).

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