Access to In Vitro Fertilization: Costs, Care and Consent

Dialogue ◽  
1991 ◽  
Vol 30 (3) ◽  
pp. 383-398 ◽  
Author(s):  
Christine Overall

What would be a genuinely caring approach to the provision of procedures of so-called artificial reproduction such as in vitro fertilization (IVF)? What are appropriate and justified social policies with respect to attempting to enable infertile persons to have offspring? These urgent questions have provoked significant disagreements among theologians, sociologists, healthcare providers, philosophers and even — or especially — among feminists. In the existing literature and in developing social policy, three different kinds of answers can be discerned. (1) Some have suggested that access to IVF should be provided as a matter of right. (2) Some existing social policies and practices imply that access to IVF is a privilege. (3) Some theorists have argued that, because of its alleged violation of family values and marital security, or because of its risks, costs, and low success rate, IVF should not be available at all. After evaluating each of these views, I shall offer a feminist alternative, describing what I think would constitute the caring provision of in vitro fertilization.

2003 ◽  
Vol 79 ◽  
pp. 1550-1554 ◽  
Author(s):  
Michael Zitzmann ◽  
Claus Rolf ◽  
Verena Nordhoff ◽  
Guido Schräder ◽  
Melanie Rickert-Föhring ◽  
...  

Author(s):  
Lorna M Frazer Moreira ◽  
Felipe A Morales Martinez ◽  
María E. Monrreal Alanís ◽  
Otto H. Valdés Martinez ◽  
Cesar D. Castro Reyes ◽  
...  

<h1><em>Resumen </em></h1><p><em>Introducción</em>: A pesar de los avances en las técnicas de reproducción asistida, la tasa de éxito en fertilización in vitro (FIV) sigue siendo modesta. La lesión endometrial, mediante histeroscopía o biopsia, previo a un ciclo de FIV, ha sido propuesta como una técnica que aumenta la probabilidad de implantación exitosa y embarazo en mujeres sometidas a FIV. <em>Objetivo</em>: Estudiar el efecto de la estimulación endometrial en la tasa de éxito de FIV. <em>Métodos</em>: Se realizó un estudio unicéntrico observacional, en pacientes sometidas a su primer ciclo de FIV. Se incluyeron mujeres entre las edades de 18-40 años que planeaban someterse a FIV con sus propios ovocitos sin exposición reciente a procedimientos disruptivos uterinos. Las pacientes elegibles se dividieron en 3 grupos. El primer grupo incluyó las que se sometieron a una histeroscopía diagnóstica previa a su ciclo de FIV, el segundo grupo incluyó aquellas que se sometieron a biopsia endometrial con cánula de Pipelle previo al ciclo de FIV y el tercer grupo incluyó a las pacientes sin intervención endometrial. <em>Resultados</em>: Se estudiaron un total de 68 pacientes (10 en el grupo 1, 27 en el grupo 2 y 31 en el grupo 3). La tasa de embarazo clínico fue estadísticamente similar en los tres grupos (33.3% para el primer grupo, 15.7% para el segundo y 16.6% para el tercero, p = 0.93). <em>Conclusión</em>: La estimulación endometrial antes del primer ciclo de FIV no ofreció beneficios adicionales en relación con implantación exitosa y/o tasas clínicas de embarazo. </p><p align="left">Palabras clave: lesión endometrial, fertilización in vitro, implantación, infertilidad, nacido vivo</p><p align="left"> </p><h1>Abstract</h1><p><em>Background</em>: Despite advances in assisted reproduction techniques, the in vitro fertilization (IVF) success rate still remains modest. Endometrial injury, through hysteroscopy or biopsy, prior to an IVF cycle, has been proposed as a technique that increases the likelihood of successful implantation and pregnancy in women undergoing IVF. <em>Aim and Objective</em>: To study the effect of endometrial stimulation on the success rate of IVF. <em>Methods</em>: An ambispective observational unicentric study was conducted in patients undergoing their first IVF cycle. Women between the ages of 18-40 who planned to undergo IVF with their own oocytes without recent exposure to uterine disruptive procedures were included. Eligible patients were divided into 3 groups. The first group included those who underwent a diagnostic hysteroscopy prior to their IVF cycle, the second group included those who underwent endometrial biopsy with a Pipelle cannula prior to the IVF cycle and the third group included patients without endometrial intervention. <em>Results</em>: A total of 68 patients were studied (10 in group 1, 27 in group 2 and 31 in group 3). The clinical pregnancy rate was statistically similar in the three groups (33.3% for the first group, 15.7% for the second group and 16.6% for the third group, p = 0.93). <em>Conclusion</em>: Endometrial stimulation before the first IVF cycle did not offer additional benefits in relation to successful implantation and / or clinical pregnancy rates</p><p align="left">Keywords: endometrial injury, in vitro fertilization, implantation, infertility, live birth</p>*****


2020 ◽  
Vol 7 (2) ◽  
pp. 108
Author(s):  
Rina Fatmawati ◽  
Shofwal Widad ◽  
Agung Dewanto

Background: Endometriosis is a chronic condition that is influenced by the hormone estrogen which affects women of childbearing age, and is associated with pelvic pain and infertility. In Vitro Fertilization (IVF) is currently the most efficient assisted reproductive technology and its high success rate is often done for infertility therapy in women associated with endometriosisObjective: The aim of this study is to determine whether postoperative endometriosis affected pregnancy outcomes in patients underwent frozen embryo transfer in IVF / ICSI programs.Method: This Research is done with a retrospective cohort design. The data was taken from medical records, research subjects who met the inclusion and exclusion criteria. The research data was collected, processed and analyzed using SPSS 23. Univariate, bivariate and multivariate data analysis was carried out to determine the effect between variablesResult: There were 458 research subjects in this study. Endometriosis patients were 119 subjects (26%). 57 subjects were categorized as minimum-mild endometriosis (47.9%) and moderate-severe subjects as many as 62 subjects (52.1%). The biochemical pregnancy rate (36.31%) and clinical pregnancy (29.4%) in patients with endometriosis was slightly higher than in non-endometriosis. But statistically it did not affect success rate of achieving biochemical (p = 0.428; RR 0.89; 95% CI: 0.71-1.24) and clinical pregnancy (p = 0.535; RR 0.883; 95% CI: 0.63- 1.22). The rate of miscarriage in postoperative endometriosis patients was higher than non-endometriosis patients (88.6% vs 80.7%) but was not statistically significant (p = 0.294; RR 1.69; 95% CI: 0.61-4.67) . Biochemical and clinical pregnancies were significantly affected by age, infertility, endometrial thickness, embryo age and embryo quality. The incidence of miscarriage was affected by the ovarian stimulation protocol.Conclusion: Endometriosis post operative statistically has no effect on pregnancy outcomes in the IVF / ICSI cycle with frozen embryo transfer compared with another cause of infertility .Keywords:Endometriosis, In Vitro Fertilization, Clinical pregnancy, biochemical pregnancy, miscarriage


2021 ◽  
Vol 2 (2) ◽  
pp. 52-63
Author(s):  
Ana Jeremić ◽  
Dragana Vuković ◽  
Srna Subanović ◽  
Jovana Broćić ◽  
Biljana Macanović

The application of preimplantation genetic testing (PGT) began in the late 1980s. Pre-implantation genetic testing, as the earliest possible method of prenatal diagnosis, enables the selection of embryos with a normal karyotype for embryo transfer. The use of preimplantation genetic testing has proven to be a useful method in the following three groups of inherited diseases: monogenic disorders (single gene defects), trinucleotide repeat disorders, and chromosomal abnormalities. The success rate of in vitro fertilization (IVF) has increased significantly since the introduction of PGT into clinical practice. This paper presents a literature review with the aim of clearly determining the role of PGT in embryo selection before embryo transfer, as well as the role of this type of testing in increasing the success rate of IVF. One of the goals of the paper is also to review the development of molecular genetic methods that are currently, or have once been, in routine use when performing PGT. The current literature is an indicator of the development and progress of molecular genetics techniques applied in PGT. At the same time, it provides an opportunity and an incentive for further extensive research that will lead to the improvement of preimplantation genetic testing and thus increase the success rate of in vitro fertilization.


2006 ◽  
Vol 9 (2) ◽  
pp. 260-265 ◽  
Author(s):  
Johan Fellman ◽  
Aldur W. Eriksson

AbstractThe temporal variation in the stillbirth rates (SBR), measured as the number of stillborn per 1000 total births, among singletons, twins and triplets was studied on Swedish birth data for the period 1869 to 2001 and comparisons with data from other populations were made. Among both single and multiple births there were marked, almost monotonously decreasing trends in the stillbirth rates. Among singletons the stillbirth rate decreased from 29.5 per 1000 in the period 1869 to 1878 to 3.4 in the period 1991 to 2001. Among twins the stillbirth rate decreased from 94 per 1000 in 1869 to 1878 to a minimum of 8.2 in 1991 to 2001 and among triplets from 166 per 1000 to a minimum of 19.8. The relative declining pattern in the SBRs was almost the same, being 88% among singletons, 91% among twins and 88% among triplets. In the 1980s and 1990s the definition of the stillbirth rate was changed in many countries, including Finland, but no changes in the definition of stillbirths have been made in Sweden. The effect of the artificial reproduction techniques, including in vitro fertilization, on the rates of multiple maternities is also discussed. It was noted especially that they had a more marked effect on the triplet than on the twinning rate.


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