The stability of pendent liquid drops. Part 2. Axial symmetry

1974 ◽  
Vol 63 (3) ◽  
pp. 487-508 ◽  
Author(s):  
E. Pitts

In a drop of liquid which hangs below a horizontal support or a t the end of a tube, the forces due to surface tension, pressure and gravity are in equilibrium. Amongst the many possible equilibrium shapes of the drop, only those which are stable occur naturally. The calculus of variations has been used to determine theoretically the stable equilibria, by calculating the energy change when the liquid in equilibrium experiences axially symmetrical perturbations under physically realistic constraints. If the energy change can be made negative, the drop is unstable. With this criterion, stable equilibria have been identified through which the naturally growing drops evolve until they reach a maximum volume, when they become unstable. These results are illustrated by calculations relating to typical experimental conditions.

1973 ◽  
Vol 59 (4) ◽  
pp. 753-767 ◽  
Author(s):  
E. Pitts

We consider a drop of liquid hanging from a horizontal support and sandwiched between two vertical plates separated by a very narrow gap. Equilibrium profiles of such ‘two-dimensional’ drops were calculated by Neumann (1894) for the case when the angle of contact between the liquid and the horizontal support is zero. This paper gives the equilibrium profiles for other contact angles and the criterion for their stability. Neumann showed that, as the drop height increases, its cross-sectional area increases until a maximum is reached. Thereafter, as the height increases, the equilibrium area decreases. This behaviour is shown to be typical of all contact angles. When the maximum area is reached, the total energy is a minimum. It is shown that the drops are stable as long as the height and the area increase together.


Author(s):  
Shong-Leih Lee ◽  
Chao-Fu Yang

The static Young-Laplace equation is solved with the geometry method to yield the bubble shape on a horizontal flat surface under various contact angles. Multi-solution modes are found. Among the many possible equilibrium shapes of the bubble, however, only the fundamental solution mode could occur naturally. The value of VAR (volume to contact area ratio) could be a good measure for stability of equilibrium bubbles. The bubble becomes less stable when VAR increases. The numerical result reveals that in the course of bubble growth (i.e. volume increases) the VAR of the bubble increases linearly until the maximum contact area is reached. After that, VAR has a sharp increase due to a decreasing contact area. Beyond the maximum volume, equilibrium bubble does not seem possible. Based on the finding, it is postulated that bubble detachment occurs somewhere between the maximum contact area and the maximum volume according to perturbations from environment. However, the postulation seems to underestimate the stability of the bubble significantly for contact angles of larger than 160 degrees. A correction is proposed in the paper. Numerical result of bubble detachment criterion is fitted with polynomial functions of the contact angle.


Equilibrium shapes and stability of rotating drops held together by surface tension are found by computer-aided analysis that uses expansions in finiteelement basis functions. Shapes are calculated as extrema of appropriate energies. Stability and relative stability are determined from curvatures of the energy surface in the neighbourhood of the extremum. Families of axisymmetric, two-, three- and four-lobed drop shapes are traced systematically. Bifurcation and turning points are located and the principle of exchange of stabilities is tested. The axisymmetric shapes are stable at low rotation rates but lose stability at the bifurcation to twolobed shapes. Two-lobed drops isolated with constant angular momentum are stable. The results bear on experiments designed to further those of Plateau (1863).


2019 ◽  
Vol 26 (5) ◽  
pp. 339-347 ◽  
Author(s):  
Dilani G. Gamage ◽  
Ajith Gunaratne ◽  
Gopal R. Periyannan ◽  
Timothy G. Russell

Background: The dipeptide composition-based Instability Index (II) is one of the protein primary structure-dependent methods available for in vivo protein stability predictions. As per this method, proteins with II value below 40 are stable proteins. Intracellular protein stability principles guided the original development of the II method. However, the use of the II method for in vitro protein stability predictions raises questions about the validity of applying the II method under experimental conditions that are different from the in vivo setting. Objective: The aim of this study is to experimentally test the validity of the use of II as an in vitro protein stability predictor. Methods: A representative protein CCM (CCM - Caulobacter crescentus metalloprotein) that rapidly degrades under in vitro conditions was used to probe the dipeptide sequence-dependent degradation properties of CCM by generating CCM mutants to represent stable and unstable II values. A comparative degradation analysis was carried out under in vitro conditions using wildtype CCM, CCM mutants and two other candidate proteins: metallo-β-lactamase L1 and α -S1- casein representing stable, borderline stable/unstable, and unstable proteins as per the II predictions. The effect of temperature and a protein stabilizing agent on CCM degradation was also tested. Results: Data support the dipeptide composition-dependent protein stability/instability in wt-CCM and mutants as predicted by the II method under in vitro conditions. However, the II failed to accurately represent the stability of other tested proteins. Data indicate the influence of protein environmental factors on the autoproteolysis of proteins. Conclusion: Broader application of the II method for the prediction of protein stability under in vitro conditions is questionable as the stability of the protein may be dependent not only on the intrinsic nature of the protein but also on the conditions of the protein milieu.


2021 ◽  
Vol 5 (3) ◽  
pp. 37
Author(s):  
Hernán Martinelli ◽  
Claudia Domínguez ◽  
Marcos Fernández Leyes ◽  
Sergio Moya ◽  
Hernán Ritacco

In the search for responsive complexes with potential applications in the formulation of smart dispersed systems such as foams, we hypothesized that a pH-responsive system could be formulated with polyacrylic acid (PAA) mixed with a cationic surfactant, Gemini 12-2-12 (G12). We studied PAA-G12 complexes at liquid–air interfaces by equilibrium and dynamic surface tension, surface rheology, and X-ray reflectometry (XRR). We found that complexes adsorb at the interfaces synergistically, lowering the equilibrium surface tension at surfactant concentrations well below the critical micelle concentration (cmc) of the surfactant. We studied the stability of foams formulated with the complexes as a function of pH. The foams respond reversibly to pH changes: at pH 3.5, they are very stable; at pH > 6, the complexes do not form foams at all. The data presented here demonstrate that foam formation and its pH responsiveness are due to interfacial dynamics.


Catalysts ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 510
Author(s):  
Majeda Khraisheh ◽  
Fares. Almomani ◽  
Gavin Walker

The separation of C3H4/C3H6 is one of the most energy intensive and challenging operations, requiring up to 100 theoretical stages, in traditional cryogenic distillation. In this investigation, the potential application of two MOFs (SIFSIX-3-Ni and NbOFFIVE-1-Ni) was tested by studying the adsorption–desorption behaviors at a range of operational temperatures (300–360 K) and pressures (1–100 kPa). Dynamic adsorption breakthrough tests were conducted and the stability and regeneration ability of the MOFs were established after eight consecutive cycles. In order to establish the engineering key parameters, the experimental data were fitted to four isotherm models (Langmuir, Freundlich, Sips and Toth) in addition to the estimation of the thermodynamic properties such as the isosteric heats of adsorption. The selectivity of the separation was tested by applying ideal adsorbed solution theory (IAST). The results revealed that SIFSIX-3-Ni is an effective adsorbent for the separation of 10/90 v/v C3H4/C3H6 under the range of experimental conditions used in this study. The maximum adsorption reported for the same combination was 3.2 mmolg−1. Breakthrough curves confirmed the suitability of this material for the separation with a 10-min gab before the lighter C3H4 is eluted from the column. The separated C3H6 was obtained with a 99.98% purity.


2021 ◽  
Vol 23 (1) ◽  
Author(s):  
Kevin Kuhlmann ◽  
Melanie Cieselski ◽  
Julia Schumann

Abstract Background In the present study, two distinct PCR methods were used for the quantification of genetic material and their results were compared: real-time-PCR (qPCR; relative quantification) and droplet digital PCR (ddPCR; absolute quantification). The comparison of the qPCR and the ddPCR was based on a stimulation approach of microvascular endothelial cells in which the effect of a pro-inflammatory milieu on the expression of vasoactive receptors was investigated. Results There was consistency in directions of effects for the majority of genes tested. With regard to the indicated dimension of the effects, the overall picture was more differentiated. It was striking that deviations were more pronounced if the measured values were on the extreme edges of the dynamic range of the test procedures. Conclusions To obtain valid and reliable results, dilution series are recommended, which should be carried out initially. In case of ddPCR the number of copies per µl should be adjusted to the low three-digit range. With regard to qPCR it is essential that the stability and reliability of the reference genes used is guaranteed. Here, ddPCR offers the advantage that housekeeping genes are not required. Furthermore, an absolute quantification of the sample can be easily performed by means of ddPCR. Before using ddPCR, however, care should be taken to optimize the experimental conditions. Strict indications for this methodology should also be made with regard to economic and timing factors.


Nanoscale ◽  
2020 ◽  
Vol 12 (2) ◽  
pp. 658-668 ◽  
Author(s):  
Rafael del Caño ◽  
Jose M. Gisbert-González ◽  
Jose González-Rodríguez ◽  
Guadalupe Sánchez-Obrero ◽  
Rafael Madueño ◽  
...  

The highly packed cetyltrimethylammonium bromide bilayer on the surface of gold nanorods synthesized by the seed-mediated procedure hampers the complete ligand exchange under experimental conditions that preserves the stability of the dispersions.


2002 ◽  
Vol 452 ◽  
pp. 163-187 ◽  
Author(s):  
C. L. BURCHAM ◽  
D. A. SAVILLE

A liquid bridge is a column of liquid, pinned at each end. Here we analyse the stability of a bridge pinned between planar electrodes held at different potentials and surrounded by a non-conducting, dielectric gas. In the absence of electric fields, surface tension destabilizes bridges with aspect ratios (length/diameter) greater than π. Here we describe how electrical forces counteract surface tension, using a linearized model. When the liquid is treated as an Ohmic conductor, the specific conductivity level is irrelevant and only the dielectric properties of the bridge and the surrounding gas are involved. Fourier series and a biharmonic, biorthogonal set of Papkovich–Fadle functions are used to formulate an eigenvalue problem. Numerical solutions disclose that the most unstable axisymmetric deformation is antisymmetric with respect to the bridge’s midplane. It is shown that whilst a bridge whose length exceeds its circumference may be unstable, a sufficiently strong axial field provides stability if the dielectric constant of the bridge exceeds that of the surrounding fluid. Conversely, a field destabilizes a bridge whose dielectric constant is lower than that of its surroundings, even when its aspect ratio is less than π. Bridge behaviour is sensitive to the presence of conduction along the surface and much higher fields are required for stability when surface transport is present. The theoretical results are compared with experimental work (Burcham & Saville 2000) that demonstrated how a field stabilizes an otherwise unstable configuration. According to the experiments, the bridge undergoes two asymmetric transitions (cylinder-to-amphora and pinch-off) as the field is reduced. Agreement between theory and experiment for the field strength at the pinch-off transition is excellent, but less so for the change from cylinder to amphora. Using surface conductivity as an adjustable parameter brings theory and experiment into agreement.


2014 ◽  
Vol 13 (1) ◽  
Author(s):  
Dariusz Wyrzykowski ◽  
Joanna Pranczk ◽  
Dagmara Jacewicz ◽  
Aleksandra Tesmar ◽  
Bogusław Pilarski ◽  
...  

AbstractA potentiometric titration method (PT) and a stopped-flow kinetic technique monitored by a UV−Vis spectroscopy have been used to characterize the stability of series of Co(II)- and Ni(II)-thiodiacetato complexes, M(TDA), in the presence of 1,10-phenanthroline (phen) or 2,2’-bipyridine (bipy) in aqueous solutions. The stability constants of the binary (1:1), ternary (1:1:1) as well as the resulting hydroxo complexes were evaluated and compared to the corresponding oxydiacetate complexes. Based on the species distribution as a function of pH the relative predominance of the species in the system over a pH range was discussed. Furthermore, the kinetic measurements of the substitution reactions of the aqua ligands to phen or bipy in the coordination sphere of the binary complexes M(TDA) were performed in the 288–303 K temperature range, at a constant concentration of phen or bipy and at seven different concentrations of the binary complexes (0.2–0.5 mM). The kinetic stability of the M(TDA) complexes was discussed in relation to the experimental conditions and the kind of the auxiliary ligands (phen/bipy). Moreover, the influence of the type of primary ligand (thiodiacetate/oxydiacetate) on the substitution rate of the auxiliary ligands was also compared.


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