Phonocephalography: a simple, low-cost non-invasive diagnostic technique

1983 ◽  
Vol 97 (12) ◽  
pp. 1133-1138 ◽  
Author(s):  
Sayed Tewfik

AbstractThis article presents the phonocephalographic data reported in one case of glomus jugulare tumour, representing local haemodynamic disturbances; and one case with an aortic lesion with pulsating tinnitus, representing systemic haemodynamic disturbances.

1981 ◽  
Vol 95 (6) ◽  
pp. 589-595
Author(s):  
Sayed Tewfik

SummaryTympanic plethysmography is a simple non-invasive diagnostic technique which is used to differentiate between intra-temporal carotid aneurysms and glomus jugulare tumours and to predict the degree of extension of the tumour. It is performed by the indirect recording of volume pressure changes of pulsating tympanic masses using a pressure transducer. The volume pressure change of the pulsating mass is transmitted to the pressure transducer through a saline-filled system.Medical technology has undergone considerable progress with the introduction of new techniques in medical diagnosis less harmful to the patient and with a reduced risk of complications. The collaboration of doctors, scientists and bioengineers has resulted in the evolution of such changes, thereby trying to replace the more aggressive or invasive diagnostic techniques. The ideal diagnostic technology is one without pain, harm or complications to the patient.Medical diagnostic technology may be classified as invasive or noninvasive. Non-invasive diagnostic technology is either active, using an external source of energy such as ultrasound (ultrasonography) or a small dose of X-rays, as in computerized axial tomography; or passive, using the energy emitted by human structures, as in plethysmography.Plethysmography is the recording of volume pressure changes. Oculoplethysmography is used to monitor extracranial occlusive carotid disease (Kartchner and McRae, 1973). The use of sound energy as an internal energy emitted by the human body has proved effective as a passive, non-invasive diagnostic technique (Tewfik, 1976, 1977).Volume pressure changes of intra-temporal carotid aneurysms have been recorded, using a pressure transducer (Tewfik, 1974).In this article the volume pressure changes of glomus jugulare tumours have been recorded and the findings compared with those obtained, and previously published, for intra-temporal carotid aneurysms. Volume pressure changes of pulsating tympanic masses may be called tympanic plethysmography. A trial of this simple non-invasive diagnostic technique for differentiating pulsating tympanic masses is here reported, together with an assessment of the technique in its ability to predict the degree of extension of glomus jugulare tumours.


2015 ◽  
Vol 4 (1) ◽  
Author(s):  
Mirko Tessari ◽  
Anna Maria Malagoni ◽  
Maria Elena Vannini ◽  
Paolo Zamboni

Currently brain perfusion can be assessed by the means of radio-invasive methods, such as single-photon emission computed tomography and positron emission tomography, or by hightech methods such as magnetic resonance imaging. These methods are known to be very expensive, with long examination time, and finally, cannot be used for assessing brain oxygen distribution in relation to exercise and/or cognition-tests. The near infrared spectroscopy (NIRS) is a non-invasive diagnostic technique. In real time it is capable of measuring tissue oxygenation using portable instrumentation with a relative low cost. We and other groups previously adopted this instrument for investigation of the oxygen consumption in the muscles at rest and during exercise. NIRS can be now used to assess brain perfusion through the intact skull in human subjects by detecting changes in blood hemoglobin concentrations. Changes in perfusion can be related to both arterial and venous problems. This novel equipment features allow for a wide field of innovative applications where portability, wearability, and a small footprint are essential. The present review shows how to use it in relation to exercise protocols of the upper and lower extremities, measured in healthy people and in conditions of arterial and chronic cerebro-spinal venous insufficiency.


1996 ◽  
Vol 110 (4) ◽  
pp. 373-375 ◽  
Author(s):  
E. Nilssen ◽  
P. J. Wormald

AbstractGlomus jugulare tumours with metastases are rare as the diagnosis of metastases in this condition can be difficult.In the past this diagnosis has been made on histology of the metastatic lesions which were identified on clinical grounds. This is one of the reasons why there have been only 20 reported cases in the literature up to 1990 (Johnstone et al., 1990). This case report examines the role of meta-iodobenzylguanidine (MIBG) scintigraphy in the diagnosis of metastases. MIBG scintigraphy is an injected radionucleotide isotope scanning technique which is cheap, non-invasive, sensitive as well as being a specific investigation for identifying sites of ectopic neuroendocrine tissue. It may also have a role in the treatment of these tumours.


2021 ◽  
Vol 2008 (1) ◽  
pp. 012013
Author(s):  
C A Romero-Beltrán ◽  
A M González-Vargas ◽  
J J Cabrera-López

Abstract Electrical bioimpedance (EBI) has gained importance as a diagnostic technique in medicine to determine the electrical properties of tissues. For example, it has been used in tissue characterization, cancer detection, and electromyography. Some of the characteristics of EBI are its low cost, the absence of irradiation during the measurement process, and its non-invasive nature. In this sense, there is interest in developing medical equipment that performs non-invasive measurements of blood pressure (BP). Electrical Impedance Plethysmography (EIP) is a technique commonly used to extract the waveform associated with BP. In this short review, we will cover research articles published in peer-reviewed journals during the last decades, and show developments in the area of EIP, with a brief discussion of relevant results and current challenges.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Supakorn Harnsoongnoen ◽  
Nuananong Jaroensuk

AbstractThe water displacement and flotation are two of the most accurate and rapid methods for grading and assessing freshness of agricultural products based on density determination. However, these techniques are still not suitable for use in agricultural inspections of products such as eggs that absorb water which can be considered intrusive or destructive and can affect the result of measurements. Here we present a novel proposal for a method of non-destructive, non-invasive, low cost, simple and real—time monitoring of the grading and freshness assessment of eggs based on density detection using machine vision and a weighing sensor. This is the first proposal that divides egg freshness into intervals through density measurements. The machine vision system was developed for the measurement of external physical characteristics (length and breadth) of eggs for evaluating their volume. The weighing system was developed for the measurement of the weight of the egg. Egg weight and volume were used to calculate density for grading and egg freshness assessment. The proposed system could measure the weight, volume and density with an accuracy of 99.88%, 98.26% and 99.02%, respectively. The results showed that the weight and freshness of eggs stored at room temperature decreased with storage time. The relationship between density and percentage of freshness was linear for the all sizes of eggs, the coefficient of determination (R2) of 0.9982, 0.9999, 0.9996, 0.9996 and 0.9994 for classified egg size classified 0, 1, 2, 3 and 4, respectively. This study shows that egg freshness can be determined through density without using water to test for water displacement or egg flotation which has future potential as a measuring system important for the poultry industry.


Author(s):  
Yan Li ◽  
Yuanyuan Zheng ◽  
Liwei Wu ◽  
Jingjing Li ◽  
Jie Ji ◽  
...  

AbstractThe conventional method used to obtain a tumor biopsy for hepatocellular carcinoma (HCC) is invasive and does not evaluate dynamic cancer progression or assess tumor heterogeneity. It is thus imperative to create a novel non-invasive diagnostic technique for improvement in cancer screening, diagnosis, treatment selection, response assessment, and predicting prognosis for HCC. Circulating tumor DNA (ctDNA) is a non-invasive liquid biopsy method that reveals cancer-specific genetic and epigenetic aberrations. Owing to the development of technology in next-generation sequencing and PCR-based assays, the detection and quantification of ctDNA have greatly improved. In this publication, we provide an overview of current technologies used to detect ctDNA, the ctDNA markers utilized, and recent advances regarding the multiple clinical applications in the field of precision medicine for HCC.


Author(s):  
Marco Vinicio Alban ◽  
Haechang Lee ◽  
Hanul Moon ◽  
Seunghyup Yoo

Abstract Thin dry electrodes are promising components in wearable healthcare devices. Assessing the condition of the human body by monitoring biopotentials facilitates the early diagnosis of diseases as well as their prevention, treatment, and therapy. Existing clinical-use electrodes have limited wearable-device usage because they use gels, require preparation steps, and are uncomfortable to wear. While dry electrodes can improve these issues and have demonstrated performance on par with gel-based electrodes, providing advantages in mobile and wearable applications; the materials and fabrication methods used are not yet at the level of disposable gel electrodes for low-cost mass manufacturing and wide adoption. Here, a low-cost manufacturing process for thin dry electrodes with a conductive micro-pyramidal array is presented for large-scale on-skin wearable applications. The electrode is fabricated using micromolding techniques in conjunction with solution processes in order to guarantee ease of fabrication, high device yield, and the possibility of mass production compatible with current semiconductor production processes. Fabricated using a conductive paste and an epoxy resin that are both biocompatible, the developed micro-pyramidal array electrode operates in a conformal, non-invasive manner, with low skin irritation, which ensures improved comfort for brief or extended use. The operation of the developed electrode was examined by analyzing electrode-skin-electrode impedance, electroencephalography, electrocardiography, and electromyography signals and comparing them with those measured simultaneously using gel electrodes.


Author(s):  
Massine GANA ◽  
Hakim ACHOUR ◽  
Kamel BELAID ◽  
Zakia CHELLI ◽  
Mourad LAGHROUCHE ◽  
...  

Abstract This paper presents a design of a low-cost integrated system for the preventive detection of unbalance faults in an induction motor. In this regard, two non-invasive measurements have been collected then monitored in real time and transmitted via an ESP32 board. A new bio-flexible piezoelectric sensor developed previously in our laboratory, was used for vibration analysis. Moreover an infrared thermopile was used for non-contact temperature measurement. The data is transmitted via Wi-Fi to a monitoring station that intervenes to detect an anomaly. The diagnosis of the motor condition is realized using an artificial neural network algorithm implemented on the microcontroller. Besides, a Kalman filter is employed to predict the vibrations while eliminating the noise. The combination of vibration analysis, thermal signature analysis and artificial neural network provides a better diagnosis. It ensures efficiency, accuracy, easy access to data and remote control, which significantly reduces human intervention.


Author(s):  
Pooja J. Mise ◽  
Sangamesh J. Mise ◽  
Aditya Mise ◽  
Margol Siddappa

Background: Transvaginal sonography (TVS) is a new diagnostic technique used for the evaluation of the female pelvis. The objective of the present study was to study the role of TVS and to assess the diagnostic accuracy in gynecological disorders.Methods: Total number of 100 patients attending OPDs with various complaints was selected by random technique of the study.  All the patients have informed consent and thorough clinical examination including general, systemic and pelvic examination was conducted after taking a detailed history then the patients underwent TVS followed by one of the procedures like fractional curettage, dilatation and curettage and abdominal hysterectomy (with or without conservation of ovaries) or conservative management with regular follow up.Results: The sensitivity of TVS in diagnosing dysfunctional uterine bleeding (DUB) and pelvic inflammatory diseases (PID) was 100% and specificity was 85.1% and 95% respectively. For fibroids and ovarian mass diagnosis, sensitivity was 68.9% and 80.9% respectively and specificity was 100%. Diagnostic accuracy of clinical diagnosis was 70.0% whereas TVS had 94.0% of diagnostic accuracy in diagnosing various gynecological disorders.Conclusions: The final outcome is that TVS examination is an important non-invasive investigation, can be used as important diagnostic method in various gynecological disorders as it has got a high diagnostic accuracy.


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