Carcinoid tumour of the larynx

1986 ◽  
Vol 100 (12) ◽  
pp. 1421-1426 ◽  
Author(s):  
J. S. Weighill ◽  
J. W. Tankel ◽  
A. Mene

SummaryCarcinoid tumours of the larynx are extremely rare, only 13 cases having previously been reported in the world literature. A case is reported here with the unusual complication of skin metastases. The true diagnosis is seldom made on the original biopsy, which is commonly reported as poorly differentiated carcinoma. A review of the literature is made with a discussion of the histological diagnosis and treatment modalities.

2001 ◽  
Vol 15 (6) ◽  
pp. 405-409 ◽  
Author(s):  
Tuya Pal ◽  
Alexander Liede ◽  
Margot Mitchell ◽  
Alain Calender ◽  
Steven A Narod

Familial cases of carcinoid tumours that are not associated with any known syndrome or disease are extremely rare. All cases reported in the world literature have involved carcinoid tumours of the gastrointestinal tract. Two cases of carcinoid tumours of the small intestine in a father and daughter are presented. Laboratory analyses did not support the hypothesis that the occurrence of carcinoid tumours in this family is a variant of the multiple endocrine neoplasia type 1 syndrome. A review of the literature on familial occurrence of intestinal carcinoid tumours in the absence of any other known carcinoid tumour-predisposing genetic syndrome is provided.


Neurosurgery ◽  
1983 ◽  
Vol 13 (5) ◽  
pp. 572-576 ◽  
Author(s):  
W.J. Levy ◽  
L. Ansbacher ◽  
J. Byer ◽  
A. Nutkiewicz ◽  
J. Fratkin

Abstract Primary tumors of the gasserian ganglion are usually benign, and secondary tumors are malignant. We report two cases of a malignant primary tumor of the gasserian ganglion, bringing the total in the world literature to five. The presentation, etiological features, and treatment of these cases are reviewed, together with a review of the literature. Preoperative differentiation from a benign tumor is not possible with certainty. A combination of operation and radiation therapy seems to be the best treatment at present.


Neurosurgery ◽  
1983 ◽  
Vol 13 (3) ◽  
pp. 322-326 ◽  
Author(s):  
Bruce Pendleton ◽  
Barton Carl ◽  
Michael Pollay

Abstract A lumbar spinal extradural ganglion cyst is reported, and the world literature on spinal ganglion cysts is reviewed. The clinical presentation, findings, etiology, and pathogenesis of these lesions are discussed.


2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Chad Purcell ◽  
Ayham Al Afif ◽  
Martin Bullock ◽  
Martin Corsten

Laryngeal secondary malignancies are rare, and most spread locoregionally from hypopharyngeal or thyroid primaries. Metastasis of ovarian carcinoma to the larynx is extremely rare. A 65-year-old woman with a history of high grade serous ovarian carcinoma was undergoing carboplatin chemotherapy for recurrence. She presented with progressive dysphagia and hoarseness; a computer tomography (CT) scan demonstrated bilateral necrotic lymphadenopathy and hypopharyngeal fullness. A hypopharyngeal mass was confirmed on examination, and operative biopsy identified it as high-grade serous ovarian. To our knowledge, this report describes the second immunohistochemically proven metastatic ovarian cancer detected in the larynx in the world literature.


1980 ◽  
Vol 25 (3) ◽  
pp. 245-249 ◽  
Author(s):  
R. Rankin ◽  
N. S. Nirodi ◽  
M. K. Browne

A case of carcinoid tumour of the oesophagus in a 54-year-old man is described and the literature is briefly reviewed. This is the third reported case in the world literature and the rarity of the disease is emphasised.


2021 ◽  
Vol 8 (2) ◽  
pp. A50-55
Author(s):  
B R Vani ◽  
Sandhyalakshmi B N ◽  
Netra M Sajjan ◽  
Panduranga C ◽  
Deepak Kumar B ◽  
...  

Background: NHL are heterogeneous group of hematolymphoid malignancy occurring in nodal and extra nodal sites. Extra nodal lymphoma (ENL) is distinct from nodal lymphomas due to varied anatomical location, morphological diversity. Methods: A retrospective observational study was conducted in the department of pathology from January 2011 till December 2019. Clinical details and other investigations were recorded. Gross morphological features were noted. Slides are reviewed microscopically and blocks were subjected to IHC for further typing cases were selected as per Dawson et al criteria. Result: During study period, ENL constituted 25 cases (29.4%) of the 85 cases of all NHL. Age range is 05 to 63 years with a mean age of 42.5 years. Male to female ratio is 2.2 :1.Head and neck is the most common site of ENHL constituting 19 cases(76%), next commonest location is in the GIT with 3 cases (12%). We had one each case of ENHL in testis, breast and spine (4% each). On IHC, 92% cases (23 cases) exhibited   B cell phenotype and the remaining 08 % (02 cases) were of T cell phenotype. Conclusion: Lymphomas in the extra nodal sites are rare but has the propensity to occur in any anatomic site. Hence a differential of lymphoma to be considered in extra nodal site. Histology with IHC enables to differentiate from poorly differentiated carcinoma as the treatment modalities and prognosis varies.


PEDIATRICS ◽  
1964 ◽  
Vol 33 (4) ◽  
pp. 587-589
Author(s):  
JOSEPH F. FRAUMENI

Previous report of a marked shift in the sex ratio of children born of mothers with acute leukemia suggested a potential clue to genetic changes in leukemia. In the study reported here, an exhaustive review of the world literature since 1930 on leukemia and pregnancy revealed that 24 males and 32 females were born alive to mothers suffering from acute leukemia, while 37 males and 28 females occurred among the liveborn offspring of mothers with chronic leukemia. These differences were not statistically significant. Within each series, the small numbers of male and female infants reported dead at birth were about equal. Since the deficiency of male live births among offspring of mothers with acute leukemia was restricted to the myeloid form, additional sex ratio studies appear indicated. The results of this study and a review of the literature reveal little, if any, evidence of a maternal-fetal transmission of leukemia.


2004 ◽  
Vol 128 (8) ◽  
pp. 922-925 ◽  
Author(s):  
Monica Garcia ◽  
Efren Buitrago ◽  
Pablo A. Bejarano ◽  
Javier Casillas

Abstract Liposarcoma is one of the most common neoplasms of adulthood. However, it is exceedingly rare in the gastrointestinal tract. To our knowledge, only 12 cases occurring in the esophagus have been reported in the world literature to date. We report the case of a 42-year-old man with a pleomorphic liposarcoma arising in the esophageal wall. The morphologic, immunophenotypic, and ultrastructural characteristics are presented, as well as the results of literature review.


2011 ◽  
Vol 125 (11) ◽  
pp. 1176-1180 ◽  
Author(s):  
H Joshi ◽  
B A Woodworth ◽  
A S Carney

AbstractObjective:To propose radiofrequency coblation as a potential treatment modality for mild to moderate epistaxis in patients with hereditary haemorrhagic telangiectasia.Method:Case reports and review of the world literature concerning coblation and other treatment modalities for epistaxis in patients with hereditary haemorrhagic telangiectasia.Results:Effective epistaxis control was achieved in four out of five cases of hereditary haemorrhagic telangiectasia. In the fifth case, we struggled to achieve haemostasis due to disease severity.Conclusion:Radiofrequency coblation is a novel technique, which was found to be a safe, effective, quick and well tolerated treatment option for epistaxis management in patients with hereditary haemorrhagic telangiectasia.


2020 ◽  
Vol 2020 (7) ◽  
Author(s):  
Derqaoui Sabrine ◽  
Bernoussi Zakia ◽  
Znati Kaoutar

Abstract Adrenal sarcomatoid carcinoma (ASC) is a very rare aggressive variant of adrenocortical carcinoma showing carcinomatous and sarcomatous differentiation. It is a poorly differentiated carcinoma with poor prognosis. The diagnosis requires careful histological and immunohistochemical investigation. We describe a new case of ASC to raise awareness on this extremely rare entity. A 27-year-old woman presented with a right flank pain. Imaging revealed a tissular mass of the right adrenal gland without metastases. After adrenalectomy, histology revealed sheets of epithelioid cells that stained for synaptophysin and Melan-A; and spindled cells staining for S-100. We have reported the clinical and histopathological features of ACS’s case; as it is an extremely rare cancer with a challenging diagnosis. There is a need for a further understanding of ASC’s biology to improve it poor prognosis.


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