Risk of adolescent offspring's completed suicide increases with prior history of their same-sex parents' death by suicide

2013 ◽  
Vol 44 (9) ◽  
pp. 1845-1854 ◽  
Author(s):  
C.-C. J. Cheng ◽  
W.-J. Yen ◽  
W.-T. Chang ◽  
K. C.-C. Wu ◽  
M.-C. Ko ◽  
...  
Keyword(s):  
Conditional Logistic Regression ◽  
Statistical Significance ◽  
Prior History ◽  
Same Sex ◽  
Birth Registry ◽  
Conditional Logistic Regression Model ◽  
Completed Suicide ◽  
Suicidal Death ◽  
History Of ◽  
Maternal Suicide

BackgroundTo investigate the risk of completed suicide in offspring during adolescence in relation to prior history of the same-sex parent's death by suicide and other causes.MethodA total of 500 adolescents who died by suicide at age 15–19 years between 1997 and 2007 were identified from the Taiwan Mortality Registration (TMR). For each case, 30 age- and time-matched controls were selected randomly from all adolescents registered in the Taiwan Birth Registry (TBR). A multivariate conditional logistic regression model was used to assess the risk of adolescent completed suicide in relation to their same-sex parent.ResultsAdolescent suicide risk was positively associated with both paternal [odds ratio (OR) 5.38, 95% confidence interval (CI) 2.17–13.33] and maternal suicide (OR 6.59, 95% CI 1.82–23.91). The corresponding risk estimates associated with paternal and maternal deaths from non-suicidal causes were much lower, at 1.88 and 1.94 respectively. The risk of suicide in male adolescents was significantly associated with prior history of paternal death by suicide (OR 8.23, 95% CI 2.96–22.90) but not of maternal death by suicide (OR 3.50, 95% CI 0.41–30.13). On the other contrary, the risk of suicidal death in female adolescents was significantly associated with prior history of maternal suicide (OR 9.71, 95% CI 1.89–49.94) but not of paternal suicide (OR 2.42, 95% CI 0.30–19.57). However, these differences did not reach statistical significance.ConclusionsAlthough limited by sample size, our study indicates that adolescent offspring suicidal death is associated with prior history of their same-sex parent's death by suicide.

THE MAGNETIC RESONANCE IMAGING OF THE LUMBAR SPINE IN OUT-PATIENTS WITH LOW BACK PAIN

2001 ◽  
Vol 05 (04) ◽  
pp. 261-267 ◽  
Author(s):  
BOHUA CHEN ◽  
STEVE LAVENDER ◽  
GUNNAR B. J. ANDERSSON
Keyword(s):  
Logistic Regression ◽  
Medical Center ◽  
Lumbar Disc ◽  
Statistical Significance ◽  
White Collar ◽  
Individual Characteristics ◽  
Blue Collar ◽  
Prior History ◽  
Spine Pathology ◽  
History Of

This paper aims to estimate the prevalence rates of MRI change in LBP out-patients and to determine the relationship between abnormalities in an MRI and personal and occupational factors. The MRI records were obtained from 200 out-patients with LBP (114 males and 86 females) who received a diagnostic MRI at St. Luke's Medical Center. The mean and standard deviation of this sample's age were 43.8 years and 14.8 years, respectively. Based on the MRI, each lumbar disc was scored as normal or degenerated. Bulging and herniated were also recorded. Each patient completed a short questionnaire that included the measures of height, weight, age, and present occupation and any history of "heavy manual labor". Occupations were grouped into white collar sedentary, white collar professional, blue collar exposed to prolonged sitting and vibration, blue collar exposed to heavy, unemployed or retired, and homemaker. Chi-square tests were used to determine the statistical significance of these trends. A multiple logistic regression was used to develop a predictive model of spine pathology based on a subject's individual characteristics and occupational classification. Normal discs were found in 26% of the patients and degenerated discs in 47.5%. There were bulging/herniated disks in 26.5%. In men who were younger than 29 years, 50% had herniated disks, and 50% were normal. Three fourth of the women in the same age group showed normal discs. Forty-three percent of the subjects reported a history of performing heavy labor. Using the logistic regression model there were two variables predictive of observable MRI pathology: age and prior history of heavy labor. The analysis indicated that an older individual who had a history and heavy labor was more likely to show one or more pathological model discs in an MRI scan.

Persistent Ethanol Drinking Increases Liver Injury Induced by Trinitrotoluene Exposure: An In-plant Case-Control Study

1991 ◽  
Vol 10 (6) ◽  
pp. 405-409
Author(s):  
Li Jie ◽  
Quan-Guan Jiang ◽  
Wei-Dong Zhong
Keyword(s):  
Risk Factors ◽  
Liver Damage ◽  
Case Control Study ◽  
Conditional Logistic Regression ◽  
Heavy Drinking ◽  
Case Control ◽  
Conditional Logistic Regression Model ◽  
Two Factors ◽  
History Of ◽  
Control Study

On the basis of a general survey conducted in a munitions plant, a case-control study was made on the various risk factors of liver damage induced by trinitrotoluene (TNT) exposure in the plant. One-hundred male cases with occupational TNT liver damage were paired with 100 male controls, one-by-one, for occupation, age and duration (years) of employment. A total of 55 possible risk factors were statistically analysed with a single factor analysis. On the basis of the single analysis, nine factors including drinking, smoking and education were further analysed with a conditional logistic regression model. A calculation was made on the odds ratio (OR) of each factor selected into the model. According to the estimated parameter of the established logistic model, the relative risk of the risk factors could be worked out. Finally, two factors, the amount of ethanol drunk on each occasion and the frequency of drinking every week were selected into the model at the level of a = 0.05. The result showed that these two factors have a dose-response relationship with their OR of occupational TNT liver damage, but there is no connection between smoking and occupational TNT liver damage and no interaction between drinking and smoking. The above results have revealed that people exposed to TNT and with a long history of heavy drinking, have a greater risk of suffering from chronic liver impairment than those that do not drink.

scholarly journals Risk Factors for Early Preterm Birth at King Salman Armed Force Hospital in 2010

2017 ◽  
Vol 5 (7) ◽  
pp. 1016-1020 ◽  
Author(s):  
Badriah Ali Alansi ◽  
Hytham Bahaeldin Mukhtar ◽  
Maher Ahmad Alazizi ◽  
Amjad Ahmad Zuiran ◽  
Areej Mohammed AL-Atawi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Preterm Birth ◽  
Placental Abruption ◽  
Statistical Significance ◽  
Preterm Births ◽  
Prior History ◽  
P Value ◽  
Multiple Gestations ◽  
History Of ◽  
Early Preterm Birth

AIM: To investigate risk factors for early preterm birth.METHODS AND MATERIAL: A retrospective comparative study was conducted at Tabuk, Kingdom of Saudi Arabia during the period from January to December 2010. Five hundred and ninety-five patient's files and delivery registry logbooks were reviewed, the following information was collected; demographic data, current and past obstetric histories. Then the early and late preterm births were compared for various risk factors. The Statistical Package for Social Sciences (SPSS version 22) was used. The Chi-square and t-test were used to test the statistical significance and a P-value<0.05 considered significant.RESULTS: Prevalence of early preterm birth was found to be 2.5% in our study group. Women at risk for early preterm birth were: primigravidas (33.7% vs. 26.2% for control), P-value 0.039, OR 1.429 and 95% CI 0.982 - 2.079); multiple gestations (87.7% vs. 95.1% for control, P-value 0.002, OR 0.368 and 95% CI 0.196 - 0.688); and patients with a prior history of placental abruption (3.7% vs. 1.0% for control, P-value 0.027, OR3.928 and 95% CI 1.1360 - 13.586).CONCLUSIONS: Current study indicated that early preterm births differed from preterm as a whole; primigravida, multiple gestations and a history of placental abruption are independent risk factors for them.

Predictors of Post-Thrombotic Ulcer after Acute DVT: The RIETE Registry

2018 ◽  
Vol 118 (02) ◽  
pp. 320-328 ◽  
Author(s):  
Jean-Philippe Galanaud ◽  
Laurent Bertoletti ◽  
Maria Amitrano ◽  
Carmen Fernández-Capitán ◽  
José Pedrajas ◽  
...  
Keyword(s):  
Venous Thromboembolism ◽  
Statistical Significance ◽  
Signs And Symptoms ◽  
Venous Ulcer ◽  
Lower Limbs ◽  
Prior History ◽  
Diabetic Patients ◽  
Vein Thrombosis ◽  
History Of ◽  
End Stage

AbstractIn patients with deep-vein thrombosis (DVT) in the lower limbs, venous ulcer is the most debilitating and end-stage clinical expression of the post-thrombotic syndrome (PTS). To date, risk factors for PTS-related ulcer in DVT patients have not been identified.We used the international observational RIETE registry to assess the evolution of PTS signs and symptoms during a 3-year follow-up period and to identify independent predictors of PTS ulcer at 1 year in patients with acute DVT.Among 1,866 eligible patients, cumulative rates of PTS ulcer at 1, 2 and 3 years were 2.7% (n = 50), 4.3% (n = 54) and 7.1% (n = 60), respectively. The proportion of patients with PTS symptoms at 1, 2 or 3 years remained stable (≈40%), while the proportion of patients with PTS signs increased slightly over time (from 49 to 53%). Prior history of venous thromboembolism (VTE) (odds ratio [OR] = 5.5 [2.8–10.9]), diabetes (OR = 2.3 [1.1–4.7]), pre-existing leg varicosities (OR = 3.2 [1.7–6.1]) and male sex (OR = 2.5 [1.3–5.1]) independently increased the risk of PTS ulcer at 1 year. Obesity also increased the risk but failed to reach statistical significance (OR = 1.8 [0.9–3.3]). DVT treatment characteristics (duration or drug) did not influence the risk.Our results evidence that after acute DVT, pre-existing leg varicosities, prior venous thromboembolism, diabetes and male gender independently increased the risk for PTS ulcer. This suggests that clinicians should consider strategies aimed to prevent ulcers in high-risk DVT patients, such as preventing VTE recurrence, use of stockings in those with pre-existing venous insufficiency, careful monitoring of diabetic patients and encouraging weight loss in obese patients.

scholarly journals SKELETAL MATURATION EVALUATION USING MANDIBULAR SECOND MOLAR CALCIFICATION STAGES

2021 ◽  
Vol 71 (3) ◽  
pp. 980-83
Author(s):  
Fakhira Nizam ◽  
Nasrullah Mengal ◽  
Mirza Tareen ◽  
Sumbal Hayat
Keyword(s):  
Skeletal Maturity ◽  
Cervical Vertebrae ◽  
Statistical Significance ◽  
Skeletal Maturation ◽  
Prior History ◽  
Second Molar ◽  
Stage 4 ◽  
History Of ◽  
Mandibular Second Molar ◽  
Maturation Index

Objective: To examine the relationship between skeletal maturity and mandibular second molar calcification stages and assessing mandibular second molar as a diagnostic tool for skeletal maturity evaluation. Study Design: Cross sectional study. Place and Duration of Study: Orthodontic department, Sandeman Provincial Hospital, Quetta, from Jan to Jun 2019. Methodology: The sample size of the study 240 comprised of equal number of males and females. Inclusion criteria was defined to include the patients (male and female) with the age from 9-16 years; on the same time, patients without facial asymmetry and without prior history of facial or neck trauma/injury or surgery were considered for the present study. Exclusion criteria was defined to exclude those patients from the study hoe had the history of bone disease and major illness in past; known cases of muscular dystrophy; any congenital malformation of cervical vertebrae and tooth caries; Low quality x-ray with poor contrast. Results: The study revealed association between Demirjian Index and Cervical Vertebrae Maturation Index stages (0.875) with the statistical significance. Demirjian Index Stage H indicated the greater percentage distribution at stage 4 and 6 of Cervical Vertebrae Maturation for males. Similarly, in females, demirjian index stages G and H showed the greater percentage at stage 4 and 6 of cervical vertebrae maturation index respectively. Conclusion: Analysis indicated that cervical vertebrae maturation index and Demirjian Index (DI) occurred earlier in femalesthan males.

Geometric variations associated with posterior communicating artery aneurysms

2021 ◽  
pp. neurintsurg-2020-017062
Author(s):  
Jian Zhang ◽  
Anil Can ◽  
Pui Man Rosalind Lai ◽  
Srinivasan Mukundan, Jr. ◽  
Victor M Castro ◽  
...  
Keyword(s):  
Massachusetts General Hospital ◽  
Conditional Logistic Regression ◽  
Statistical Significance ◽  
Three Dimensional ◽  
Size Ratio ◽  
Posterior Communicating Artery ◽  
Sensitivity Analyses ◽  
Control Group ◽  
Conditional Logistic Regression Model ◽  
Small Aneurysms

BackgroundHemodynamic stress, conditioned by the morphology of the surrounding vasculature, plays an important role in aneurysm formation. Our goal was to identify image-based location-specific parameters that are associated with posterior communicating artery (PCoA) aneurysms.MethodsThree-dimensional morphological parameters obtained from CT angiography or digital subtraction angiography from 187 patients with unilateral PCoA aneurysms, diagnosed at the Brigham and Women’s Hospital and Massachusetts General Hospital between 1990 and 2016, were evaluated. In order to control for genetic and clinical risk factors, we chose the contralateral unaffected PCoA as a control group. We examined diameters and angles of the surrounding parent and daughter vessels. Univariable and multivariable statistical analyses were performed to determine statistical significance. Sensitivity analyses with small aneurysms (≤5 mm) only and an unmatched analysis of 432 PCoA aneurysms and 197 control patients without PCoA aneurysms were also performed.ResultsIn a multivariable conditional logistic regression model we showed that smaller diameter size ratio (OR 1.45×10−5, 95% CI 1.12×10−7 to 1.88×10−3) and larger daughter-daughter angle (OR 1.04, 95% CI 1.02 to 1.07) were significantly associated with PCoA aneurysm presence after correcting for other variables. In subgroup analyses of small aneurysms (≤5 mm) and in an unmatched analysis the significance and direction of these results were preserved.ConclusionsLarger daughter-daughter angles and smaller diameter size ratio are significantly associated with the presence of PCoA aneurysms. These simple parameters can be utilized to guide the risk assessment for the formation of PCoA aneurysms in high risk patients.

Diltiazem Does Not Prevent Postoperative Atrial Fibrillation After Thoracoscopic Lobectomy

2021 ◽  
pp. 155698452199420
Author(s):  
Madeline R. Lederer ◽  
Alexa Deemer ◽  
Franzes A. Liongson ◽  
Nicholas Roma ◽  
Charles T. Lee ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Statistical Significance ◽  
Univariate Analysis ◽  
Postoperative Atrial Fibrillation ◽  
Prior History ◽  
Odds Ratios ◽  
Gender History ◽  
Thoracoscopic Lobectomy ◽  
History Of ◽  
Ischemic Attack

Objective Thoracoscopic lobectomy is associated with lower rates of adverse events compared to thoracotomy. Despite this, postoperative atrial fibrillation (POAF) occurs in at least 10% of patients. Our objective is to determine if prophylaxis with diltiazem significantly reduced POAF events. Methods Patients without prior history of atrial fibrillation who underwent thoracoscopic lobectomy from 2007 to 2016 at one institution were analyzed in a retrospective cohort study utilizing a prospective database. Patients treated from 2007 to 2012 received no prophylaxis. Patients treated after 2012 received diltiazem postoperatively. All patients were monitored with continuous telemetry postoperatively. Multivariate direct logistic regression was performed to determine independent predictors of POAF. We report adjusted odds ratios and accompanying 95% confidence intervals, with P < 0.05 denoting statistical significance. Results The final regression model included 416 patients (52 with POAF, 364 without). In univariate analysis, the variables of body mass index and history of congestive heart failure, diabetes, or hypertension, and prophylaxis status did not meet inclusion criteria. Age, gender, history of stroke or transient ischemic attack, and vascular disease were included. Only ages 65 to 74 ( P = 0.03) and ≥75 ( P = 0.02), compared to <65, were statistically significant predictors of POAF. Adjusted odds ratios of ages 65 to 74 and ≥75 were 2.88 and 2.62, respectively. Conclusions Diltiazem prophylaxis did not significantly reduce POAF incidence following thoracoscopic lobectomy. Further study is warranted since POAF remains an unwanted source of morbidity and cost for lobectomy patients.

Language Onset and Concomitant Speech and Language Problems in Subgroups of Stutterers and Their Siblings

1982 ◽  
Vol 25 (4) ◽  
pp. 482-486 ◽  
Author(s):  
Robin A. Seider ◽  
Keith L. Gladstien ◽  
Kenneth K. Kidd
Keyword(s):  
Family History ◽  
Same Sex ◽  
Speech And Language ◽  
Negative Family History ◽  
Late Talkers ◽  
Language Problems ◽  
History Of ◽  
Language Onset

Time of language onset and frequencies of speech and language problems were examined in stutterers and their nonstuttering siblings. These families were grouped according to six characteristics of the index stutterer: sex, recovery or persistence of stuttering, and positive or negative family history of stuttering. Stutterers and their nonstuttering same-sex siblings were found to be distributed identically in early, average, and late categories of language onset. Comparisons of six subgroups of stutterers and their respective nonstuttering siblings showed no significant differences in the number of their reported articulation problems. Stutterers who were reported to be late talkers did not differ from their nonstuttering siblings in the frequency of their articulation problems, but these two groups had significantly higher frequencies of articulation problems than did stutterers who were early or average talkers and their siblings.

Rebellious Wallflowers and QueerTangueras: The Rise of Female Leaders in Buenos Aires’ Tango Scene

2018 ◽  
Vol 36 (2) ◽  
pp. 173-197
Author(s):  
Juliet McMains
Keyword(s):  
Social Norms ◽  
Buenos Aires ◽  
Female Leaders ◽  
Same Sex ◽  
Overlapping Communities ◽  
Heterosexual Women ◽  
Bisexual And Transgender ◽  
History Of

This paper interrogates the history of same-sex dancing among women in Buenos Aires' tango scene, focusing on its increasing visibility since 2005. Two overlapping communities of women are invoked. Queer tangueras are queer-identified female tango dancers and their allies who dance tango in a way that attempts to de-link tango's two roles from gender. Rebellious wallflowers are women who practice, teach, perform, and dance with other women in predominantly straight environments. It is argued that the growing acceptance of same-sex dancing in Argentina is due to the confluence of four developments: 1) the rise of tango commerce, 2) innovations of tango nuevo, 3) changing laws and social norms around lesbian, gay, bisexual, and transgender rights, and 4) synergy between queer tango dancers and heterosexual women who are frustrated by the limits of tango's gender matrix. The author advocates for increased alliances between rebellious wallflowers and queer tangueras, who are often segregated from each other in Buenos Aires' commercial tango industry.

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