Childhood adversity and psychosis: a systematic review of bio-psycho-social mediators and moderators

2020 ◽  
Vol 50 (11) ◽  
pp. 1761-1782
Author(s):  
Lucia Sideli ◽  
Robin M. Murray ◽  
Adriano Schimmenti ◽  
Mariangela Corso ◽  
Daniele La Barbera ◽  
...  

AbstractThe association between childhood adversity (CA) and psychosis has been extensively investigated in recent years. An increasing body of research has also focused on the mediating or moderating role of biological and psychological mechanisms, as well as other risk factors that might account for the link between CA and psychosis. We conducted a systematic search of the PsychINFO, Embase, Ovid, and Web of Science databases for original articles investigating the role of genetic vulnerabilities, environmental factors, psychological and psychopathological mechanisms in the association between CA and psychosis up to August 2019. We included studies with individuals at different stages of the psychosis continuum, from subclinical psychotic experiences to diagnosed disorders. From the 28 944 records identified, a total of 121 studies were included in this review. Only 26% of the studies identified met the criteria for methodological robustness. Overall, the current evidence suggests that CA may be associated with psychosis largely independently of genetic vulnerabilities. More consistent and robust evidence supports interaction between early and recent adversities, as well as the mediating role of attachment and mood symptoms, which is suggestive of an affective pathway between CA and psychosis across the continuum from subclinical experiences to diagnosable disorder. This review highlighted numerous methodological issues with the existing literature, including selection bias, heterogeneity of measurement instruments utilised, and lack of control for potential confounders. Future research should address these limitations to more accurately estimate mediation and moderation effects on the CA-psychosis association to inform the development of preventive interventions.

2021 ◽  
pp. 0192513X2110555
Author(s):  
Bülent Dilmaç ◽  
Ali Karababa ◽  
Tolga Seki ◽  
Zeynep Şimşir ◽  
M. Furkan Kurnaz

The present study aimed to investigate the mediating role of state anxiety in the relationship between the fear of COVID-19 and relationship happiness among married individuals. An additional aim of the study also tested the moderating role of joint family activities between state anxiety and relationship happiness. The study sample consisted of 1713 married individuals (1031 women and 682 men). The study findings showed both the significant direct associations among the studied variables and the mediating role of state anxiety in the relationship between fear of COVID-19 and relationship happiness. It also found that the path of state anxiety to relationship happiness among married individuals having family activities was significantly lower than those who did not. Directions for future research and application were discussed.


2017 ◽  
Vol 5 (1) ◽  
pp. 55-63
Author(s):  
Sarah Zafar

The current study examined the role of support for creativity in determining creativity with the mediating role of epistemic curiosity and moderating role of trust in leadership. Data were collected from 321 employees working in telecom sector of Pakistan situated in Rawalpindi, Islamabad, Sialkot and Lahore. Regression analysis suggested that support for creativity is positively associated with creativity and epistemic curiosity, whereas, there is a positive relationship between epistemic curiosity and creativity. Epistemic curiosity further mediates the relationship between support for creativity and creativity of employees, while trust in leadership moderates the relationship between Support for creativity and creativity of employees. Results are discussed in the light of existing environment in the private sector organizations of Pakistan. The paper concludes by discussing study limitations and future research directions.


10.28945/4616 ◽  
2020 ◽  
Vol 15 ◽  
pp. 155-174
Author(s):  
Caiyun Zhuang ◽  
Guohong Chen ◽  
Xiaoyu Du

Aim/Purpose: Drawing on theories of organizational learning, this study analyzes the mechanism of Internet integration capability affecting knowledge generation by 399 Chinese enterprises. This paper will further explore whether there is a moderating role of learning orientation in the mechanism of Internet integration capability affecting enterprise knowledge generation. Background: The Internet has gradually integrated into the enterprise innovation system and penetrated into all aspects of technological innovation, which has promoted the integration and optimization of resources inside and outside the organization. However, there is limited understanding of how the combination of the Internet and integration capability can drive enterprise knowledge generation. Methodology: The study uses survey data from 399 organizations in China. Through structural equation modeling, this study assesses the relationship between Internet integration capability, organizational learning, knowledge generation, and uses PROCESS macro program to test the mediated moderation effect of learning orientation. Contribution: First, this study provides empirical evidence for managers to better build Internet integration capability and ambidextrous learning to promote enterprise knowledge generation. Second, this study highlights the important moderating role of learning orientation in the mediating role of ambidextrous learning. Findings: First, the study confirms the mediating role of exploratory learning and exploitative learning in knowledge generation driven by Internet integration capability. Second, the results show that when organizations have a strong learning orientation, the indirect path of Internet integration capability influencing knowledge generation through exploratory learning will be enhanced. Recommendations for Practitioners: Enterprises should pay full attention to the improvement of internet integration capability and ambidextrous learning to promote knowledge generation. In addition, enterprises should establish a good learning atmosphere within the organization to strengthen the bridge role of exploratory learning between Internet integration capability and knowledge generation. Recommendation for Researchers: Researchers could collect data from countries with different levels of economic development to verify the universal applicability of the proposed theoretical model. Impact on Society: This study provides references for enterprises using Internet integration capability to promote their knowledge generation capability under the internet background. Future Research: Future research can compare the impact of Internet integration capability on knowledge generation in different industries.


2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Ying Zhang ◽  
Haoyu Chen ◽  
Ersi Liu ◽  
Yunwu He ◽  
Edwin Cheng

Purpose The purpose of this paper is to study the influence of cooperative and competitive personalities on tacit knowledge sharing (TKS) by exploring the mediating role of organizational identification (OI) and the moderating role of perceived organizational support (POS) among Chinese employees. Design/methodology/approach Conducting a network survey of ordinary employees from Chinese listed companies (2019) as the research objects, the authors collect 298 valid samples for research. The authors apply confirmatory factor analysis to test the reliability and validity of the constructs, structural equation modeling to verify the direct effect and the PROCESS macro to test the mediating and moderating effects. Findings The results show that there is a positive relationship between cooperative personality (COP) and TKS, and there is an inverted U-shaped relationship between competitive personality (CMP) and TKS. OI plays a mediating role between COP and TKS, while POS plays a negative moderating role between COP and TKS. Research limitations/implications This paper only takes Chinese employees as the research sample, and future research can make a cross-cultural comparison between the impacts of cooperative and competitive personalities on employees’ behaviors. Practical implications The results of this study suggest that enterprises should actively cultivate the COP of employees, and managers should refrain from intervening in the behaviors of employees with COP. At the same time, for employees with CMP, managers should guide them to control their competitive tendency at a reasonable level. The conclusions of this paper also suggest that managers should pay attention to the cultivation of employees’ OI. Originality/value This study plugs the gap in research on the impacts of cooperative and competitive personalities on TKS. It makes a contribution to the research development of COP and CMP and their influence mechanisms on employees’ behaviors. In addition, the negative moderating effect of POS on COP–TKS link verifies the correctness of Y theory. Studying the relationships among personality traits (cooperative and competitive personalities), cognition (OI) and behaviors (TKS), this paper makes a contribution to such a research stream.


2018 ◽  
Vol 6 (2) ◽  
pp. 14-22
Author(s):  
Maimoona Tariq ◽  

The Purpose of this study is to enhance the understanding of relationship between co-worker support, and project efficiency in the presence of mediating role of team cohesiveness and moderating role of Project culture. The context of this study is projects that are taking place in Pakistan. Data were collected from 100 participants, who participated in project as a team member, using structured questionnaire. Findings suggested that project efficiency is affected by co-coworker support in a positive manner, in the presence of team cohesiveness. Regression analysis for moderating and mediating variables was performed using Model 4 and 1 of the Process Macros for SPSS presented by Preacher and Hayes. It has been found that team cohesiveness mediates the relationship of co-worker support and project efficiency. Moreover, the project culture plays a moderating role on the relation of co-worker support and team cohesiveness. In the end the implications for project managers and future research are discussed.


2017 ◽  
Vol 16 (3) ◽  
pp. 155-159 ◽  
Author(s):  
Peizhen Sun ◽  
Jennifer J. Chen ◽  
Hongyan Jiang

Abstract. This study investigated the mediating role of coping humor in the relationship between emotional intelligence (EI) and job satisfaction. Participants were 398 primary school teachers in China, who completed the Wong Law Emotional Intelligence Scale, Coping Humor Scale, and Overall Job Satisfaction Scale. Results showed that coping humor was a significant mediator between EI and job satisfaction. A further examination revealed, however, that coping humor only mediated two sub-dimensions of EI (use of emotion and regulation of emotion) and job satisfaction. Implications for future research and limitations of the study are discussed.


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