Immunocytochemistry. A Review of Methodology for Electron Microscopic Applicaiton
1974 ◽
Vol 32
◽
pp. 328-329
Keyword(s):
Immunocytochemistry is a powerful investigative approach in which one of the most exacting examples of specificity, that of the reaction of an antibody with its antigen, isused to localize tissue and cell specific molecules in situ. Following the introduction of fluorescent labeled antibodies in T950, a large number of molecules of biological interest had been studied with light microscopy, especially antigens involved in the pathogenesis of some diseases. However, with advances in electron microscopy, newer methods were needed which could reveal these reactions at the ultrastructural level. An electron dense label that could be coupled to an antibody without the loss of immunologic activity was desired.
1971 ◽
Vol 29
◽
pp. 258-259
◽
Keyword(s):
1967 ◽
Vol 25
◽
pp. 132-133
1991 ◽
Vol 49
◽
pp. 430-431
1972 ◽
Vol 30
◽
pp. 156-157
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2002 ◽
Vol 50
(8)
◽
pp. 1067-1080
◽
2000 ◽
Vol 6
(3)
◽
pp. 195-201
◽
1955 ◽
Vol 102
(5)
◽
pp. 573-580
◽
1998 ◽
Vol 12
(3)
◽
pp. 199-202
◽