scholarly journals Folate status in women of childbearing age with obesity: a review

2017 ◽  
Vol 30 (2) ◽  
pp. 265-271 ◽  
Author(s):  
Silvia Maffoni ◽  
Rachele De Giuseppe ◽  
Fatima Cody Stanford ◽  
Hellas Cena

AbstractSeveral studies have described a positive association between elevated BMI and birth defects risk. Data on plasma concentration of folate in pregnant women with obesity have shown values far below those recommended, regardless of diet, while folate levels should increase before pregnancy to reduce neural tube defects. We report a descriptive review of the most recent studies (from 2005 to 2015) to evaluate folate status through a population of women of childbearing age affected by obesity. The literature contains few studies, which present conflicting results regarding folate status in non-pregnant women of childbearing age affected by obesity, and it appears that there is a modification in folate metabolism, with a reduction in plasma folate levels and an increase in erythrocyte folate uptake. In conclusion, the folate status in women of childbearing age should be assessed by both plasma and erythrocyte levels to start a personalised and more adequate supplementation before conception. Further studies need to be conducted in a larger population, which take into account variables that can affect folate metabolism, such as dietary intake, lifestyle and genetic factors, oral contraceptives or other drug use, previous weight-loss programmes, or a history of bariatric surgery.

2016 ◽  
Vol 19 (16) ◽  
pp. 2897-2905 ◽  
Author(s):  
Kathryn E Bradbury ◽  
Sheila M Williams ◽  
Jim I Mann ◽  
Indrawati Oey ◽  
Cindy Aitchison ◽  
...  

AbstractObjectiveTo estimate the folate status of New Zealand women of childbearing age following the introduction, in 2010, of a new voluntary folic acid fortification of bread programme.DesignThe 2011 Folate and Women’s Health Survey was a cross-sectional survey of women aged 18–44 years carried out in 2011. The survey used a stratified random sampling technique with the Electoral Roll as the sampling frame. Women were asked about consumption of folic-acid-fortified breads and breakfast cereals in a telephone interview. During a clinic visit, blood was collected for serum and erythrocyte folate measurement by microbiological assay.SettingA North Island (Wellington) and South Island (Dunedin) city centre in New Zealand.SubjectsTwo hundred and eighty-eight women, of whom 278 completed a clinic visit.ResultsGeometric mean serum and erythrocyte folate concentrations were 30 nmol/l and 996 nmol/l, respectively. Folate status was 30–40 % higher compared with women of childbearing age sampled as part of a national survey in 2008/09, prior to the introduction of the voluntary folic acid bread fortification programme. In the 2011 Folate and Women’s Health Survey, reported consumption of fortified bread and fortified breakfast cereal in the past week was associated with 25 % (P=0·01) and 15 % (P=0·04) higher serum folate concentrations, respectively.ConclusionsSerum and erythrocyte folate concentrations have increased in New Zealand women of childbearing age since the number of folic-acid-fortified breads was increased voluntarily in 2010. Consumption of fortified breads and breakfast cereals was associated with a higher folate status.


GYNECOLOGY ◽  
2018 ◽  
Vol 20 (6) ◽  
pp. 48-52
Author(s):  
E N Kravchenko ◽  
R A Morgunov

The aim of the study. Assess the importance of pregravid preparation and outcomes of pregnancy and childbirth, depending on the reproductive attitudes of women in the city of Omsk. Materials and methods. The study included 92 women who were divided into groups: group A (n=43) - women whose pregnancy was planned; group B (n=49) - women whose pregnancy occurred accidentally. Each group was divided into subgroups depending on age: from 18 to 30 and from 31 to 49 years. For each patient included in the study, a specially designed map was filled out. These patients were interviewed at the City Clinical Perinatal Center. Results. Comparative analysis revealed the relationship between the reproductive settings of women of childbearing age and the peculiarity of the course of pregnancy and childbirth in these patients. Summary. The majority of women of fertile age are married: in subgroup AA - 25 (96.2%), AB - 13 (76.5%), BA - 25 (92.6%), BB - 20 (91.0%). The predominant number of women of fertile age have one or more abortions: in subgroup AA - 12 (46.2%), AB - 6 (35.3%), in subgroups of comparison BA - 8 (29.6%), BB - 6 (27.3%). More than half of the women of fertile age surveyed have a history of untreated cervical pathology (from 40.8% to 64.7%). The course of pregnancy in women planning pregnancy in most cases proceeded without complications: in subgroup AA - 13 (50.0%), AB - 11 (64.7%). The most common cause of complicated pregnancy in women whose pregnancy occurred accidentally is the threat of spontaneous miscarriage: in subgroup BA - 15 (55.6%), BB - 16 (72.7%). The uncomplicated course of labor more often [subgroup AA - 19 (73.0%), AB - 12 (70.6%)] was observed in women whose pregnancy was planned and they were motivated to give birth to a healthy child.


2017 ◽  
Vol 18 (1) ◽  
Author(s):  
K Michael Hambidge ◽  
Nancy F Krebs ◽  
Ana Garcés ◽  
Jamie E Westcott ◽  
Lester Figueroa ◽  
...  

2018 ◽  
Vol 55 (5) ◽  
pp. 633-641 ◽  
Author(s):  
Sarah F. Schillie ◽  
Lauren Canary ◽  
Alaya Koneru ◽  
Noele P. Nelson ◽  
Wade Tanico ◽  
...  

2016 ◽  
Vol 3 (1) ◽  
pp. 48
Author(s):  
Annisaa’ Nurmasari ◽  
Fatimah Fatimah ◽  
Febrina Suci Hati

<p>HIV infection in pregnant women can threaten the life of the mother and the mother can transmit the virus to their babies. Sleman PHC registered 2 people including one pregnant woman and one women of childbearing age in the year of 2014. Incidence of pregnant women suffering from HIV-AIDS in 2014 is 1 patients and detected from PITC test results for 7 weeks in a row is 1 patient. And in January year of 2015 found 1 patient with 3 times test and the results was positive. The purpose of this study was to determine relationship between Knowledge Level of Pregnant women about HIV/AIDS and Behaviour of PITC (Provider Initiated Test and Counselling) test. This study was a quantitative analysis of correlation with cross-sectional design. The population of this study were all pregnant women checkups at the health center in Yogyakarta Sleman. The sampling technique was used accidental sampling study which consisted of 72 respondents. The analysis used univariate and bivariate. The results showed that most respondents aged 20-35 (72.2%), senior high school education (47.2%) and work as a housewife (IRT) (38.9%). Most respondents have good knowledge about HIV/AIDS were 50 respondents (69.4%). Most respondents perform checks PITC were 71 respondents (98.6%). There was no relationship between knowledge level of pregnant women about HIV/AIDS and Behaviour of PITC (p-value=0.243&gt;0.005). In Conclusion, There was no relationship between knowledge level of pregnant women about HIV/AIDS and Behaviour of PITC in Sleman, Yogyakarta.</p>


2018 ◽  
Vol 2018 ◽  
pp. 1-5 ◽  
Author(s):  
Nour Abdul Halim ◽  
Imad Uthman ◽  
Rayan Rammal ◽  
Hazem I. Assi

Idiopathic granulomatous mastitis is a rare benign inflammatory breast disease that affects women of childbearing age with a history of breastfeeding. It usually presents as an enlarging breast mass that can greatly mimic breast cancer. Moreover, it does not have a specific radiographic finding, so the only way to reach a definitive diagnosis is by core biopsy and histology. Furthermore, a consensus regarding the best treatment modality has not been reached yet. In this report, we describe the cases of two patients who suffered from this disease, and to our knowledge, such a report is the first of its kind to address this topic in this region. Therefore, because of its uncommon nature and obscure presentation, we hereby report two cases of idiopathic granulomatous mastitis. The clinical presentation, treatment, and pathological findings are described, and a literature review on idiopathic granulomatous mastitis will be reported.


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