Diseases of the prostate

2004 ◽  
Vol 14 (2) ◽  
pp. 119-128
Author(s):  
A Cannon ◽  
P Abrams
Keyword(s):  
Benign Prostatic Hyperplasia ◽  
Prostate Gland ◽  
Prostatic Hyperplasia ◽  
Histological Diagnosis ◽  
British Association ◽  
International Continence Society ◽  
Elderly Men ◽  
International Consultation ◽  
Stromal Tissue

Benign enlargement of the prostate gland does not always cause symptoms or obstruction to the flow of urine. Old terminology, for example, ‘prostatism’ can therefore be misleading, and the British Association of Urological Surgeons (BAUS), the International consultation on BPH and the International Continence Society accept the definitions given below:Benign prostatic hyperplasia (BPH) is a histological diagnosis. The first pathological signs appear under the age of 40 years, followed by a rapid increase in prevalence with age; 80% of 80-year-olds have evidence of BPH. The onset of BPH is dependent on the presence of functioning testes and increasing age. It is characterized by a combination of atrophy and proliferation in both glandular and stromal tissue. Although BPH is detectable in most elderly men, it does not always cause enlargement of the prostate, symptoms, or obstruction to the flow of urine.

Clinical Evaluation of Homoeopathic Medicines in Benign Prostatic Hyperplasia

2019 ◽  
Vol 32 (02) ◽  
pp. 082-087
Author(s):  
Neeraj Gupta ◽  
Rahul Singh ◽  
R.K. Saxena
Keyword(s):  
Benign Prostatic Hyperplasia ◽  
Prostate Gland ◽  
Prostatic Hyperplasia ◽  
Elderly Men ◽  
Symptomatic Benign Prostatic Hyperplasia ◽  
Daily Lives ◽  
Clinically Significant ◽  
American Urological Association ◽  
Interrupted Flow

Background Symptomatic benign prostatic hyperplasia (BPH) is a common condition in elderly men and has a significant impact on their daily lives. Surgical procedures are currently used for the conventional treatment for BPH; but they have been associated with clinically significant adverse effects in patients. Objectives The main purpose of this article is to evaluate the role of homoeopathic medicines for the treatment of BPH. Materials and Methods Clinically diagnosed 30 subjects of BPH were given homoeopathy treatment and followed up for a period of 1 year. Homoeopathic medicines were prescribed to the subjects according to the principles of homoeopathy. Effects of homoeopathic medicines were analysed periodically by American Urological Association score (AUA score) and ultrasonography. Results Marked amelioration of symptoms and reduction in size of prostate gland in BPH subjects were observed after homoeopathic treatment when analysed by AUA score and ultrasonography. There was marked reduction in various symptoms of BPH like nocturia, straining, incomplete sensation after urination, interrupted flow of urination with dribbling of urine and urgency significantly from 21.60 ± 4.64 units to 12.23 ± 3.68, that is, ∼57% reduction in symptoms of obstruction of bladder problem. The reduction was statistically significant (p = 0.001). However, transabdominal pelvic ultrasonic scan did not show statistically significant results. Conclusion Homoeopathic medicines can prove to be an alternative treatment of BPH.

The International Continence Society “Benign Prostatic Hyperplasia” Study: The Bothersomeness of Urinary Symptoms

1997 ◽  
Vol 157 (3) ◽  
pp. 885-889 ◽  
Author(s):  
T.J. Peters ◽  
J.L. Donovan ◽  
H.E. Kay ◽  
P. Abrams ◽  
J.J.M.C.H. de la Rosette ◽  
...  
Keyword(s):  
Benign Prostatic Hyperplasia ◽  
Prostatic Hyperplasia ◽  
Urinary Symptoms ◽  
International Continence Society

scholarly journals In Vivo Effects of Polymerized Anthocyanin from Grape Skin on Benign Prostatic Hyperplasia

Nutrients ◽  
2019 ◽  
Vol 11 (10) ◽  
pp. 2444 ◽  
Author(s):  
Young-Jin Choi ◽  
Meiqi Fan ◽  
Yujiao Tang ◽  
Hyun Pil Yang ◽  
Ji-Young Hwang ◽  
...  
Keyword(s):  
Benign Prostatic Hyperplasia ◽  
Cyclin D1 ◽  
Specific Antigen ◽  
Prostatic Hyperplasia ◽  
Nuclear Antigen ◽  
Elderly Men ◽  
Grape Skin ◽  
Common Chronic Disease ◽  
Metabolic Imbalance

Benign prostatic hyperplasia (BPH) is a common chronic disease of the urinary system among elderly men. Especially, the metabolic imbalance of androgen in elderly men is one of the leading causes of BPH. Dihydrotestosterone (DHT) and converted testosterone by 5-α reductase type 2 (5AR2), binding with androgen receptor (AR), affect prostate proliferation and growth. In BPH, levels of androgen signaling-related protein expression are shown highly. Androgen signaling induces the overexpression of prostate-specific antigen (PSA) and cell proliferation factor such as proliferating cell nuclear antigen (PCNA) and cyclin D1. Grape skin anthocyanins are well known for their antioxidative, anti-cancer, anti-diabetes, anti-inflammatory, antimicrobial, and anti-aging activities. Polymerized anthocyanin (PA) downregulated the expression of androgen signaling-related proteins such as 5AR2, AR, and PSA in LNCaP cell lines. Furthermore, we investigated the effects on PA in testosterone propionate-induced BPH rat experiments. The oral administration of PA decreased the prostate weight in rats with TP-induced BPH. PA decreased the AR, 5AR2, SRC1, PSA, PCNA, and cyclin D1 expression in prostate tissues and the serum DHT levels, ameliorated the BPH-mediated increase of Bcl-2 expression, and increased the Bax expression. These results suggest that PA may be a potential natural therapeutic agent for BPH treatment.

scholarly journals 250 Gambaran Benigna Prostat Hiperplasia di RSUP Prof. Dr. R. D. Kandou Manado Periode Januari 2014 – Juli 2017

e-CliniC ◽  
2017 ◽  
Vol 5 (2) ◽  
Author(s):  
Filzha Adelia ◽  
Alwin Monoarfa ◽  
Angelica Wagiu
Keyword(s):  
Benign Prostatic Hyperplasia ◽  
Transurethral Resection ◽  
Prostate Gland ◽  
Descriptive Study ◽  
Prostatic Hyperplasia ◽  
Transurethral Resection Of Prostate ◽  
Age Group ◽  
Flow Disturbance ◽  
Main Complaint ◽  
Common Action

Abstract: Benign prostatic hyperplasia (BPH) is defined as stromal cell proliferation of prostate gland which causes enlargement of the gland. It manifests as urine flow disturbance, difficult to urinate, and desire to urinate, however, the urine emission is low. In 2013, Indonesia has 9.2 million cases of BPH among men aged over 60 years. This study was aimed to obtain the profile of BPH cases at Prof. Dr. R. D. Kandou Hospital Manado in the period of January 2014 to June 2017. This was a retrospective descriptive study at Medical Record Installation of Prof. Dr. R. D. Kandou Hospital. The results showed that during that period of time, the highest percentage of cases was in 2016 (38.46%) and the most common age group was 61-70 years old (46.15%). The main complaint among the patients was difficult to urinate and the most frequently performed action was transurethral resection of prostate (TURP) (51.28%). Conclusion: In this study, BPH cases were most common at the age group 61-70 years old. Moreover, TURP was the most common action performed.Keywords: benign prostatic hyperplasia Abstrak: Benigna prostat hiperplasia (BPH) didefinisikan sebagai proliferasi dari sel stromal pada prostat, yang menyebabkan pembesaran kelenjar tersebut. Manifestasi BPH dapat berupa terganggunya aliran urin, sulit buang air kecil (BAK), dan keinginan buang air kecil namun pancaran urin lemah. Pada tahun 2013 di Indonesia terdapat 9,2juta kasus BPH, umumnya diderita laki-laki berusia di atas 60 tahun. Penelitian ini bertujuan untuk mendapatkan gambaran kasus BPH di RSUP Prof. Dr. R. D. Kandou Manado periode Januari 2014 – Juli 2017. Jenis penelitian ialah deskriptif retrospektif , yang dilakukan di Instalasi Rekam Medik RSUP Prof. Dr. R. D. Kandou Manado. Hasil penelitian menunjukkan bahwa jumlah kasus BPH tertinggi pada tahun 2016 (38,46%) dan pada kelompok usia 61-70 tahun (46,15%). Keluhan utama semua pasien ialah sulit BAK. Tindakan yang paling sering digunakan yaitu transurethral resection of prostate (TURP) (51,28%). Simpulan: Kasus BPH terutama ditemukan berusia 61-70 tahun. Tindakan yang paling sering dilakukan yaitu reseksi prostat transuretra (TURP).Kata kunci: benigna prostat hiperplasia

scholarly journals Prostate Volume Measurement by Ultrasonography Over 40 Years Age of Bangladeshi Population

2022 ◽  
Vol 8 (1) ◽  
pp. 350-356
Author(s):  
Towhida Naheen
Keyword(s):  
Benign Prostatic Hyperplasia ◽  
Prostate Volume ◽  
Prostate Gland ◽  
Digital Rectal Examination ◽  
Volume Measurement ◽  
Prostatic Hyperplasia ◽  
P Value ◽  
College Hospital ◽  
Histologic Diagnosis ◽  
Bangladeshi Population

Background: Benign prostatic hyperplasia (BPH) or benign prostatic hypertrophy, is a histologic diagnosis status characterized by proliferation of the ‘glandular elements’ of the prostate, which may lead to an enlarged prostate gland. In many studies, people over the age of 40 years found as the most vulnerable for BPH. Ultrasonography is a prominent method to determine prostate volume or size. Aim of the study: The aim of the present study was to evaluate the prostate volume measurement for the Bangladeshi population over the age of 40 years by ultrasonography.Methods:This prospective, observational study was conducted in the Department of Anatomy, Chattogram Medical College Hospital, Chattogram, Bangladesh during the period from January 2019 to December 2020. In total 157 suspected patients of benign prostatic hyperplasia were selected as the study population. All patients were clinically diagnosed for BPH, based on the present prostate symptoms and digital rectal examination. To measure the prostate volume, abdominal ultrasonography was performed for all the patients. After enucleation, another ultrasonogram was performed for all the patients to measure the existing sizes of the prostates of the patients. All the data were processed, analyzed, and disseminated by MS-word and SPSS programs as per need.Results:Finally, in this study in analyzing the volumes of the prostates of the participants according to the abdominal ultra-sonographic reports of pre-operative stage we observed, in 9%, 34%, 31%, 30%, 21% and 32% patients, the prostate sizes (In cc) were <20, 21-40, 41-60, 61-80, 81-100 and >100 cc respectively. On the other hand, after enucleation, in 11.46%, 24.20%, 28.66%, 27.39%, 7.01% and 1.27% patients, the prostate sizes (In cc) were found <20, 21-40, 41-60, 61-80, 81-100 and >100 cc respectively. The mean changes of prostate sizes between pre- and post-operative stages among the participant was not significant where the P value was found 0.464.Conclusion:The findings of this study support the applications of abdominal ultrasonographic evaluation for suspected benign prostatic hyperplasia patients to know about the exact volumes of their prostates for selecting the appropriate surgical approach.

scholarly journals Prostatic Artery Embolization for Benign Prostatic Hyperplasia Treatment: A Russian Multicenter Study in More Than 1,000 Treated Patients

2020 ◽  
Vol 14 (3) ◽  
pp. 155798832092391
Author(s):  
Armais Kamalov ◽  
Sergei Kapranov ◽  
Alexander Neymark ◽  
Dmitry Kurbatov ◽  
Boris Neymark ◽  
...  
Keyword(s):  
Benign Prostatic Hyperplasia ◽  
Prostate Gland ◽  
Prostatic Hyperplasia ◽  
Urethral Strictures ◽  
Minimally Invasive Surgical ◽  
Surgical Methods ◽  
Superselective Embolization ◽  
Postembolization Syndrome ◽  
Observation Period

Benign prostatic hyperplasia (BPH) is one of the most common diseases of the genitourinary system. The prevalence of BPH increases in men with advancing age. While transurethral resection of the prostate gland entails complications such as retrograde ejaculation, urinary incontinence, hematuria, urethral strictures, bladder neck sclerosis, and other adverse events, it is necessary to apply minimally invasive surgical methods such as superselective embolization of the prostatic arteries (PAE), particularly Proximal Embolization First Then Distal Embolization (PErFecTED). The data from 1,015 BPH patients who underwent endovascular surgery demonstrate the benefits of PErFecTED treatment during 24 months after surgery. Both Quality of Life score and International Prostate Symptom Score were around three times better in the PErFecTED group and remained stable during the entire observation period. However, the technique needs to be improved due to the high risk of postembolization syndrome.

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