Alcoholism in a Geriatric Outpatient Clinic of São Paulo-Brazil

1997 ◽  
Vol 9 (1) ◽  
pp. 95-103 ◽  
Author(s):  
Edson S. Hirata ◽  
Osvaldo P. Almeida ◽  
Rossana R. Funari ◽  
Eva L. Klein
Keyword(s):  
Family History ◽  
Alcohol Abuse ◽  
Outpatient Clinic ◽  
Age At Onset ◽  
Positive Family History ◽  
Sao Paulo ◽  
Elderly Subjects ◽  
São Paulo ◽  
Heavy Smoking ◽  
History Of

Alcohol abuse and dependence are an increasing health problem among the elderly, but there is only scanty information about their prevalence and associated risk factors in developing countries. The authors set out to evaluate the prevalence and associated clinical/demographic features of alcoholism in a sample of male elderly subjects attending a Geriatric Primary Health Outpatient Clinic in a State University Hospital in the City of São Paulo-Brazil. Three hundred four patients were assessed with the Brazilian version of the Michigan Alcoholism Screening Test and a semistructured questionnaire designed to investigate associated features. Lifetime alcoholism was present in 15.1% of the sample, although only 4.3% were active drinkers. Patients classified as “cases” were younger than their nonalcoholic counterparts (70.61 vs. 73.31), and there was a mild, though not significant, excess of Blacks and Mulattos among the former (32.6% vs. 15.9%). Cases were also more likely to rely on their family for financial support (59.0% vs. 43.5%) and to acknowledge a positive family history of alcoholism (51.4% vs. 31.2%). Alcohol abuse or dependence was further associated with heavy smoking (58.7% vs. 44.0%). The authors concluded that alcoholism in this Brazilian elderly sample was likely to be associated with an earlier age at onset of medical problems, financial dependence, Black/Mulatto race smoking, and positive family history of alcohol abuse/dependence. The authors suggest that the use of standardized methods of assessment of alcoholism in general medical settings may increase the detection of case and contribute to improved health measures for the management of these patients.

scholarly journals Head Tremor in Cervical Dystonia

2000 ◽  
Vol 27 (2) ◽  
pp. 137-142 ◽  
Author(s):  
P.K. Pal ◽  
A. Samii ◽  
M. Schulzer ◽  
E. Mak ◽  
J.K.C. Tsui
Keyword(s):  
Family History ◽  
Genetic Association ◽  
Cervical Dystonia ◽  
Age At Onset ◽  
Positive Family History ◽  
Head Tilt ◽  
The Body ◽  
Hand Tremor ◽  
Head Tremor ◽  
History Of

ABSTRACT:Objective:To compare the clinical characteristics, natural history, and therapeutic outcome of patients with cervical dystonia (CD) with head tremor (HT+) and without head tremor (HT-).Methods:We prospectively evaluated 114 consecutive patients of CD over a 9-month period with a detailed questionnaire. Chi-square and t-tests were employed for statistical analysis.Results:Seventy-eight (68.4%) patients had head tremor and 27 of them (34.6%) had tremor as one of the first symptoms. Age at onset of symptoms were similar in HT+ and HT- groups; however there was a higher prevalence in women in the former group (66.7% vs. 41.7%; p=0.01). HT+ patients had more frequent positive family history of essential-like hand/head tremor (21.8% vs. 5.5%; p<0.05), associated neck pain (92.3% vs. 77.8%; p<0.05), and essential-like hand tremor (40% vs. 8.3%; p<0.001). They also appeared to have more frequent history of preceding head/neck trauma (14.1% vs. 8.3%), frequent head rotation (88.5% vs. 69.4%) and antecollis (12.8% vs. 5.5%) but less often head tilt (37.2% vs. 47.2%) and gestes antagonistes (60.2% vs. 75%) than the HT- patients; however these differences were not statistically significant. The frequency of prior psychiatric illnesses, the incidence of dystonias in other parts of the body, frequency of retrocollis and shoulder elevation, and spontaneous remission were similar in the two groups.Conclusions:Head tremor is common in CD and is more commonly associated with hand tremor and family history of tremor or other movement disorders. This supports a possible genetic association between CD and essential tremor (ET). Linkage studies are required to evaluate the genetic association between CD and ET.

scholarly journals Predictors of alcohol responsiveness in dystonia

Neurology ◽  
2018 ◽  
Vol 91 (21) ◽  
pp. e2020-e2026 ◽  
Author(s):  
Johanna Junker ◽  
Valerie Brandt ◽  
Brian D. Berman ◽  
Marie Vidailhet ◽  
Emmanuel Roze ◽  
...  
Keyword(s):  
Family History ◽  
Movement Disorders ◽  
Rating Scale ◽  
Age At Onset ◽  
Positive Family History ◽  
Self Report ◽  
Cross Sectional ◽  
Total N ◽  
Generalized Dystonia ◽  
History Of

ObjectiveTo determine predictors of alcohol responsiveness in a large cohort of patients with dystonia.MethodsA total of 2,159 participants with dystonia were prospectively enrolled in the cross-sectional Dystonia Coalition multicenter study. Patients with secondary, combined, or confirmed genetic dystonia (total n = 164) or unknown alcohol responsiveness (n = 737) were excluded. Patients answered a standardized questionnaire and were clinically examined using a standardized video protocol and the Burke-Fahn-Marsden Dystonia Rating Scale. Alcohol responsiveness was determined by patients' self-report.ResultsA total of 1,258 patients with isolated dystonia (mean age: 59.5 ± 12.2 years; 898 women) met the inclusion criteria; 369 patients (29.3%) reported improvement of dystonia after alcohol consumption. Alcohol responsiveness was not related to sex (p = 0.742), age (p = 0.715), or severity of dystonia (p = 0.623). Age at onset was lower in patients who responded to alcohol (p < 0.001). Alcohol responsiveness differed across dystonia subgroups (multifocal/generalized > segmental [p = 0.014]; cervical and laryngeal > cranial and limb [p < 0.001]) and was related to a positive family history of movement disorders (p = 0.001), and presence of tremor (p < 0.001).ConclusionThe association of alcohol responsiveness with a positive family history for movement disorders, generalized dystonia, and an earlier age at onset suggests that patients with dystonia who have an underlying genetic contribution may be more likely to respond beneficially to alcohol. The fact that dystonic tremor may respond to alcohol is in keeping with the observation that the intake of GABAergic drugs may have a beneficial effect in a proportion of patients.

Age at Onset of Bilateral Breast Cancer, the Presence of Hereditary BRCA1, BRCA2, CHEK2 Gene Mutations and Positive Family History of Cancer

2009 ◽  
Vol 32 (4) ◽  
pp. 182-188 ◽  
Author(s):  
Elżbieta Skasko ◽  
Anna Kluska ◽  
Anna Niwińska ◽  
Ewa Kwiatkowska ◽  
Aneta Bałabas ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Family History ◽  
Age At Onset ◽  
Positive Family History ◽  
Bilateral Breast Cancer ◽  
Gene Mutations ◽  
History Of ◽  
Brca1 Brca2 ◽  
I Gene ◽  
History Of Cancer

scholarly journals Epidemiological and Clinical Aspects of Cleft Hand: Case Series From a Tertiary Public Hospital in São Paulo, Brazil

Hand ◽  
2018 ◽  
Vol 14 (6) ◽  
pp. 814-818
Author(s):  
Diego F. Falcochio ◽  
Antonio C. Da Costa ◽  
Clarissa P. I. Durigan ◽  
Valdenia Das G. Nascimento ◽  
Claudio Santili ◽  
...  
Keyword(s):  
Family History ◽  
Positive Family History ◽  
Clinical Manifestations ◽  
Case Series ◽  
Sao Paulo ◽  
Congenital Deformity ◽  
Clinical Aspects ◽  
São Paulo ◽  
Cleft Hand ◽  
Hands And Feet

Background: Cleft hand is a rare and congenital deformity that affects hands and feet and can be associated with other malformations. The objective was to evaluate the epidemiological and clinical aspects of cleft hand patient in a case series. Methods: Baseline characteristics associated with this deformity, such as sociodemographic characteristics, affected upper limb side, family history, clinical manifestations, and the degree of deficiency according to Barsky, Manske and Halikis, and Valenti classifications, were analyzed in 38 patients treated in the Department of Orthopedic Surgery of the Irmandade da Santa Casa de Misericórdia de São Paulo, Brazil. Results: A predominance of typical hands as classified by Barsky, types II and IV by Manske and Halikis, and type IV by Valenti was found. A high frequency of typical cases (55.3%), as defined by Barsky, had a positive family history ( P = .031) and were associated with other clinical manifestations (44.7%), when compared with atypical cleft hand patients ( P < .001). Conclusion: In our study, there were more typical cleft hands than atypical, and they were more commonly associated with family history and other clinical manifestations.

scholarly journals Benign breast tumors: epidemiological profile and therapeutic conduct at the escola paulista de medicina

Mastology ◽  
2020 ◽  
Vol 30 (Suppl 1) ◽  
Author(s):  
João Bueno Vitor Peixoto ◽  
Joaquim Teodoro Araújo ◽  
Simone Elias ◽  
Afonso Celso Pinto Nazário ◽  
Gil Facina
Keyword(s):  
Breast Cancer ◽  
Family History ◽  
Medical Records ◽  
Dropout Rate ◽  
Sao Paulo ◽  
São Paulo ◽  
History Of ◽  
Epidemiological Profile ◽  
Epidemiological Characteristics

Introduction: Breasts represent an important site for the development of diseases. It is known that 80% of the palpable masses of the breast are of benign origin. Benign breast diseases range from inflammatory to neoplastic processes. Objectives: to evaluate the clinical and epidemiological characteristics of patients diagnosed with benign breast tumor at the Mastology outpatient clinic of the Universidade Federal de São Paulo (UNIFESP). Methods: 1,532 medical records, available on the electronic platform PEP-HUHSP through the ICD D24 (benign breast cancer) and N63 (unspecified breast nodule), of patients referred to the service between July 2008 and July 2017 were reviewed. After applying exclusion criteria, 403 medical records were submitted to data collection and tabulation in Excel, followed by statistical analysis using the IBM SPSS Statistics 23 software. The study in question was approved by the Research Ethics Committee of UNIFESP (CEP UNIFESP), in the Teaching and Research Coordination of Hospital São Paulo – Hospital Universitário/UNIFESP (CoEP of HSP-HU/UNIFESP) and exempted from the application of the Informed Consent by the same organs. Results: In the 9-year period, the following results were obtained: mean age was 39.3 years. Comorbidities: smoking (16.4%), SAH (16.8%) and dyslipidemia (6.3%). Family history of breast and/or ovarian cancer accounted for 16.6%. Mean age of menarche and menopause, respectively, were 12.7 and 42.5 years. Causes of referral: "alteration in image examination" (38.3%), "lump in the breast" (33.3%), "follow-up due to previous nodules" (16.5%). Anatomopathological report: fibroadenoma (41%), breast cysts (16%), phylloid tumors (3%), and papilloma (1%). Mean number of consultations per patient until discharge or abandonment of follow-up: three. Choice behavior: expectant (85.2%). Conclusion: The epidemiological profile of patients referred to the UNIFESP tertiary mastology service was mainly composed of women of childbearing age and nulliparous women, whose main comorbidities were smoking and SAH, in the great majority with no family history of breast cancer. Regarding the consultation, the main reason for referral is the findings on imaging exams, and, specially, patients would bring their breast USG along, which surpassed mammography by 34.1%. The choice for biopsy was restricted, present in approximately 1/3 of the cases, but pointed out that the most prevalent nodule is fibroadenoma, followed by phylloid and papilloma tumors. Nevertheless, there was a predilection for expectant conduct. On average, there were regular follow-ups for 1.5 years, followed by a significant dropout rate.

Attention Problems among Children with a Positive Family History of Alcohol Abuse or Dependence and Controls

2006 ◽  
Vol 13 (1) ◽  
pp. 1-5 ◽  
Author(s):  
Sven Barnow ◽  
Marc Schuckit ◽  
Tom Smith ◽  
Carsten Spitzer ◽  
Harald-J. Freyberger
Keyword(s):  
Family History ◽  
Alcohol Abuse ◽  
Positive Family History ◽  
Attention Problems ◽  
History Of

Elite da Liberdade: a contribution to the history of black clubs in Brazil

2020 ◽  
Vol 9 (1) ◽  
pp. 396-411
Author(s):  
Petrônio José Domingues
Keyword(s):  
Social Inclusion ◽  
Black Identity ◽  
Sao Paulo ◽  
São Paulo ◽  
Educational Discourse ◽  
History Of ◽  
The Creation

This article investigates the trajectory of the Grêmio Dramático, Recreativo e Literário Elite da Liberdade (the Liberdade Elite Guild of Drama, Recreation, and Literature), a black club active in São Paulo, Brazil, from 1919 to 1927. The aim is to reconstruct aspects of the club’s history in light of its educational discourse on civility, which was used as a strategy to promote modern virtues in the black milieu. By appropriating the precepts of civility, Elite da Liberdade helped construct a positive black identity, enabled the creation of bonds of solidarity among its members, and made itself a place of resistance and struggle for social inclusion, recognition, and citizens’ rights.

scholarly journals The association between diabetes and thyroid cancer risk: a hospital-based case-control study in China

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Meng Wang ◽  
Wei-Wei Gong ◽  
Feng Lu ◽  
Ru-Ying Hu ◽  
Qing-Fang He ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Family History ◽  
Case Control Study ◽  
Positive Family History ◽  
Case Control ◽  
Diabetes Duration ◽  
Family History Of Diabetes ◽  
Thyroid Cancer Risk ◽  
History Of ◽  
Control Study

Abstract Background Previous studies have indicated inconsistent relationships of diabetes with thyroid cancer risk, yet little is known in China. In this study, we aimed to investigate the associations between diabetes, diabetes duration and the risk of thyroid cancer in Chinese population. Methods A 1:1 matched case-control study was performed between 2015 and 2017 in Zhejiang Province including 2,937 thyroid cancer cases and 2,937 healthy controls. Odds ratios (ORs) with 95 % confidence intervals (CIs) for thyroid cancer were estimated in logistic regression models. Specific effects stratified by age, as well as sex, body mass index (BMI) and family history of diabetes were also examined. Results Overall, neither diabetes (OR = 0.75, 95 % CI: 0.21–2.73) nor diabetes duration (OR = 0.14, 95 % CI: 0.02–1.22 for diabetes duration ≦ 5 years; OR = 2.10, 95 % CI: 0.32–13.94 for diabetes duration > 5 years) was significantly associated with thyroid cancer. In stratified analyses, significant lower risk of thyroid cancer was observed among subjects with diabetes and shorter diabetes duration ( ≦ 5 years), but limited to those who were aged more than 40 years, female, overweight/obese and had positive family history of diabetes. Conclusions Diabetes and shorter diabetes duration were significantly associated with decreased risk of thyroid cancer in individuals characterized by older age, female sex, higher BMI and positive family history of diabetes.

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