Eosinophilic myocarditis in an adolescent: a case report and review of the literature

2012 ◽  
Vol 23 (2) ◽  
pp. 277-283 ◽  
Author(s):  
Ilhan Aslan ◽  
Marcus Fischer ◽  
Kai T. Laser ◽  
Nikolaus A. Haas

AbstractEosinophilic myocarditis is a rare disease occurring mainly in adulthood. It is generally known to be caused by autoimmune diseases, parasitic infections, hypersensitivity to drugs or substances, and after vaccinations. We describe the case of a 15-year-old adolescent, who presented initially with flu-like symptoms, as well as syncope. Subsequently, catecholaminergic treatment had to be initialised because of cardiac failure. Peripheral eosinophil count was normal at admission and at the time of endomyocardial biopsy. The biopsy, however, proved the diagnosis of eosinophilic myocarditis, but the causative agent remained unclear despite intensive diagnostic work-up. Cardiac magnetic resonance imaging showed signs of acute myocardial oedema and a delayed enhancement in the basal inferolateral segments consistent with acute myocarditis. Under treatment with corticosteroids, angiotensin-converting enzyme inhibitor, and warfarin, we accomplished a rapid and complete recovery of cardiac function and histology. This unique case of eosinophilic myocarditis is rare in childhood. The differential diagnosis and diagnostic pathway is discussed, and a review of the literature and therapeutic options based on the literature is performed.

2021 ◽  
Vol 11 (3) ◽  
pp. 246-249
Author(s):  
Mohammad Kamrul Ahsan ◽  
Md Rashedul Islam

Dermatofibrosarcoma protuberans (DFSP) is a locally invasive and slow growing tumor of the subcutaneous tissue. It rarely metastasizes but progressive and recurs frequently after surgical excision. The trunk and proximal extremities are the most common sites of the disease. A 53-year-old woman presented to dermatology outpatient department with a 3-cm, firm, violaceous and multinodular mass located on the left upper shoulder. Diagnostic work-up including magnetic resonance imaging and histopathological findings of biopsy were consistent with DFSP. The patient underwent wide local excision with skin flap reconstruction. No recurrence has been observed during ten months of follow-up. BIRDEM Med J 2021; 11(3): 246-249


2018 ◽  
Vol 9 ◽  
Author(s):  
Monika Obara-Moszynska ◽  
Justyna Rajewska-Tabor ◽  
Szymon Rozmiarek ◽  
Katarzyna Karmelita-Katulska ◽  
Anna Kociemba ◽  
...  

Neurosurgery ◽  
2003 ◽  
Vol 52 (3) ◽  
pp. 706-710 ◽  
Author(s):  
Robert D. Ecker ◽  
John L. Atkinson ◽  
Douglas A. Nichols

Abstract OBJECTIVE AND IMPORTANCE A unique case of delayed ischemic deficit after resection of a large intracranial dermoid is presented. CLINICAL PRESENTATION A 23-year-old woman, 36 hours after the uneventful gross total resection of a large intracranial dermoid cyst, slowly developed a progressive mixed aphasia and right hemiparesis. Magnetic resonance imaging and magnetic resonance angiography revealed small infarcts of the left putamen and temporal-occipital junction and a vasospastic tapering of the left M1 segment. INTERVENTION Angiography confirmed severe vasospastic tapering of the left M1 and M2 segments. Endovascular treatment successfully restored flow in the left superior division. However, the initial attempt at low-pressure dilation of the inferior division led to vessel rupture. Seven months after reoperation for emergent trapping of the M1 segment, the patient made an excellent recovery, with only mild right-hand incoordination. CONCLUSION Ruptured dermoid cysts are a risk for early and delayed cerebral ischemia, and endovascular treatment of dermoid-encased vessels may carry a higher risk for rupture.


2020 ◽  
Vol 10 (2) ◽  
Author(s):  
Norman Firth ◽  
Abdulhameed Alsarraf ◽  
Nathan Vujcich ◽  
Omar Kujan

Odontogenic keratocyst (OKC) and ameloblastomas are distinct histopathologically diagnosed odontogenic lesions of the oral cavity. Both are primarily located in the posterior regions of the mandible, however, they can involve the maxilla as well. The occurrence of both an OKC and ameloblastoma in a patient is very uncommon. This case demonstrated such a lesion in the mandible of a 57 years old female. The diagnostic work-up and features of both lesions are illustrated with special focus on histopathological variances distinguishing OKC from ameloblastoma with the support of immunohistochemistry. This case highlights the importance of identifying accurate diagnoses for such lesions which may prompt clinical implications. Clinico-pathologic understanding of both lesions signifies the need for careful management plan and prevention of recurrence. Previously reported simultaneous occurrences of odontogenic cysts and/or tumors in the oral cavity are also reviewed.


2020 ◽  
Vol 129 (7) ◽  
pp. 645-648
Author(s):  
Andrew K. Fuller ◽  
Hilary C. McCrary ◽  
M. Elise Graham ◽  
Jonathan R. Skirko

Objectives: To discuss the presentation and management of infants with arhinia or congenital absence of the nose. Methods: This case report describes an infant with arhinia that was diagnosed prenatally. In addition to a discussion of the case, a review of the literature was completed to define appropriate postnatal work-up and management. Results: The patient is a term male infant, diagnosed with arhinia on ultrasound and magnetic resonance imaging (MRI) performed at 21-weeks gestational age. Upon birth, the patient was subsequently intubated, followed by tracheostomy due to complete nasal obstruction. Through a genetics evaluation, the patient was found to be heterozygous for the SMCHD1 gene, with hypomethylation at the D4Z4 locus. Plans for reconstruction will be based on future imaging and the development of any nasal patency, however, the patient’s family plans to utilize a prosthetic nose until the patient is older. Conclusion: Arhinia is a rare condition causing respiratory distress in the neonatal period. While stabilization of the airway is the first priority, further management is not clearly defined given the rarity of the malformation. This case discusses stabilization of the airway with a review of treatment and reconstructive options.


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