Psychotropic drug use in a sample of general population in the Sardinia region

2003 ◽  
Vol 12 (4) ◽  
pp. 287-292 ◽  
Author(s):  
Mauro Giovanni Carta ◽  
Maria Carolina Hardoy ◽  
Mariangela Cadeddu ◽  
Gioia Mura ◽  
Anna Laura Floris ◽  
...  
Keyword(s):  
European Union ◽  
Drug Use ◽  
General Population ◽  
General Practitioners ◽  
Psychotropic Drug ◽  
The European Union ◽  
Research Support ◽  
Cross Sectional ◽  
Psychotropic Drug Use ◽  
Depressive Episodes

SummaryAims - To present the results of an epidemiologic research about psychotropic drug use inSardinia. Methods - Cross-sectional study on a sample of 1040 subjects randomly selected from registers. Setting - Community survey on three areas of Sardinia region. Evaluation: interviews carried out byphysicians by means of Italian version of the Composite International Diagnostic Interview Simplified.Drug consumption was evaluated concerning last week before the interview. Main Outcome Measures: point prevalence. Results - The rate of adults of the general population that consumed benzodiazepines was 10.1%, antidepressants 4.2%, 14.7% of the sample was using psychotropic drugs. 60% of subjects with diagnosis of ICD-10 Depressive Episod did not have the right pharmacologic treatment. A relevant proportion of subjects without lifetime psychiatric diagnosis (anxiety and/or depression) used antidepressants (0.8%). The pharmacologic therapies were managed by psychiatrics in 44.2% of cases, antidepressants were managed by general practitioners in 31.8% of subjects. Conclusions - The research underlines an increase of meet needs in subjects affected by depressive episodes against a previous Sardinian survey carried out over ten years ago. This change is parallel to a more frequent management of therapies by general practitioners. Their role seems to become more relevant in treating depressive illness.Declaration of InterestMauro Giovanni Carta has received grants and research support from Regione Autonoma della Sardegna, Council of the European Union, European Union DGXII, GlaxoSmithKline, Pfizer, Lundbeck, Pharmacia, Recordati. Maria Carolina Hardoy has received grants and research support from University of Pisa, GlaxoSmithKline, Pfizer, Farmades. Bernardo Carpiniello has received grants and research support from GlaxoSmithKline, Pfizer, Recordati, Janssen Cilag, EliLilly, Astra Zeneca.

scholarly journals Change in psychotropic drug use among community-dwelling people aged 75 years and older in Finland: repeated cross-sectional population studies

2011 ◽  
Vol 23 (8) ◽  
pp. 1278-1284 ◽  
Author(s):  
Franciska Desplenter ◽  
Charlotte Caenen ◽  
Jolein Meelberghs ◽  
Sirpa Hartikainen ◽  
Raimo Sulkava ◽  
...  
Keyword(s):  
Drug Use ◽  
Psychotropic Drug ◽  
Adverse Drug Events ◽  
Community Dwelling ◽  
Cross Sectional ◽  
Psychotropic Drug Use ◽  
Random Samples ◽  
Antidepressant Use ◽  
Status Differences ◽  
Compare And Contrast

ABSTRACTBackground: Older people are at high risk of experiencing psychotropic-related adverse drug events. The objective of this study was to compare and contrast the use of psychotropic drugs among community-dwelling people aged ≥75 years in 1998 and 2004.Methods: Comparable random samples of people aged ≥75 years were extracted from the population register in Kuopio, Finland, in 1998 (n = 700) and 2003 (n = 1000). In 1998 and 2004, 523 and 700 community-dwelling people respectively participated in nurse interviews, during which demographic, diagnostic and drug use data were elicited. Logistic regression was used to compute unadjusted and adjusted odds ratios (ORs) and 95% confidence intervals (CIs) for the prevalence of psychotropic drug use in 2004 compared to 1998.Results: The unadjusted prevalence of total psychotropic (37.3% and 38.4%, OR 1.05; 95% CI 0.83–1.33), anxiolytic, hypnotic and sedative (29.6% and 31.3%, OR 1.08, 95% CI 0.85–1.38), and antidepressant (10.7% and 11.9%, OR 1.12, 95% CI 0.78–1.61) use were similar in 1998 and 2004. There was a decrease in the unadjusted prevalence of antipsychotic use (9.2% and 5.7%, OR 0.60; 95% CI 0.39–0.93). After adjusting for socioeconomic and health status differences, there was an increase in the prevalence of total psychotropic (adjusted OR 1.31, 95% CI 1.01–1.70) and antidepressant (OR 1.59, 95% CI 1.06–2.40) use.Conclusion: The unadjusted prevalence of psychotropic drug use remained stable between 1998 and 2004. However, in adjusted analyses there was a small increase in the prevalence of any psychotropic drug use and antidepressant use specifically.

Management of Anxiety and Depressive Disorders in Patients ≥ 65 Years of Age by Homeopath General Practitioners versus Conventional General Practitioners, with Overview of the EPI3-LASER Study Results

Homeopathy ◽  
2018 ◽  
Vol 107 (02) ◽  
pp. 081-089 ◽  
Author(s):  
Gérard Duru ◽  
Jean Vetel ◽  
Karine Danno
Keyword(s):  
Drug Use ◽  
Clinical Improvement ◽  
General Practitioners ◽  
Psychotropic Drug ◽  
Depressive Disorders ◽  
Multivariate Logistic Regression Analysis ◽  
Prise En Charge ◽  
Psychotropic Drug Use ◽  
Study Results ◽  
The Impact

Background The increasing use of psychotropic drugs to treat anxiety and depressive disorders (ADDs) is concerning. According to the study, ‘Etude Pharmacoépidémiologique de l'Impact de Santé Publique des modes de prise en charge pour 3 groupes de pathologies’ (EPI3)-LASER, adult ADD patients who consult a general practitioner prescribing homeopathic medicines (GP-Ho) report less psychotropic drug use and are marginally more likely to experience clinical improvement than those receiving conventional care. We determined whether these observations also apply to patients ≥ 65 years old in the EPI3 cohort. Methods The EPI3-LASER study, conducted in France between March 2007 and July 2008, was a nationwide, observational survey of the three most common reasons for primary care consultation, including ADD, and the impact of the GPs' prescribing preferences: homeopathy (GP-Ho), conventional medicines (GP-CM) or mixed prescriptions (GP-Mx). This sub-analysis included 110 patients ≥ 65 years old with ADD from the EPI3 cohort who consulted either a GP-CM or GP-Ho. Socio-demographic and medical data and details of any medications prescribed were collected at inclusion. Information regarding the patients' functional status (Hospital Anxiety and Depression Scale [HADS)]) was obtained via a telephone interview 72 hours after inclusion, and at 1, 3 and 12 months post-inclusion. Medication use and outcome were determined over the 12-month period. Differences between the GP-CM and GP-Ho groups were assessed by multivariate logistic regression analysis. Results One hundred and ten patients were recruited and 87 (79.1%) with ADD (HADS ≥ 9) at the 72-hour interview were evaluated (age range: 65–93 years, 82.8% female). Patients who consulted a GP-Ho were more likely (odds ratio [OR] = 10.38, 95% confidence interval [CI]: 1.33–81.07) to have clinical improvement (HADS < 9) after 12 months than those in the GP-CM group. Patients who consulted a GP-Ho reported less psychotropic drug use (OR = 22.31 [95% CI: 2.20–226.31]) and benzodiazepine use (OR = 60.63 [95% CI: 5.75–639.5]) than GP-CM patients. Conclusions Management of ADD patients aged ≥ 65 years by GP-Ho appears to have a real public health interest in terms of effectiveness and lower psychotropic drug use.

Self-reported psychotropic drug use and associated factors in a French community sample

1992 ◽  
Vol 22 (1) ◽  
pp. 181-190 ◽  
Author(s):  
P. Pariente ◽  
J. P. Lépine ◽  
J. Lellouch
Keyword(s):  
Drug Use ◽  
Psychotropic Drug ◽  
Community Sample ◽  
Age Groups ◽  
Household Survey ◽  
Well Being ◽  
Cross Sectional ◽  
Logistic Analysis ◽  
Psychotropic Drug Use ◽  
History Of

SYNOPSISDrug use was examined in a French general population adult sample from a household survey conducted in 1987–8 in a newly built town near Paris. Psychotropic drug use was measured by the percentage of subjects reporting their use during the past week. It was prominently represented by benzodiazepines (90% of psychotropic users), differed strongly between genders (4·6% in men, 10·2% in women) and age groups (higher after 40 years). A lifetime history of major depressive episode (MDE) or of anxiety disorders was associated with a higher proportion of psychotropic drug use. Psychotropic drug use also went with a current well-being questionnaire score. Using a logistic analysis, the following set of variables held for women: well-being score, history of both MDE and anxiety disorder, age, and marital status. Making allowance for the cross-sectional nature of this retrospective survey, these finding confirmed the relatively high level of benzodiazepine drug use in an urban French community sample and emphasized its association with mental health status.

Only 10% of the psychotropic drug use for neuropsychiatric symptoms in patients with dementia is fully appropriate. The PROPER I-study

2016 ◽  
Vol 28 (10) ◽  
pp. 1589-1595 ◽  
Author(s):  
Klaas van der Spek ◽  
Debby L. Gerritsen ◽  
Martin Smalbrugge ◽  
Marjorie H. J. M. G. Nelissen-Vrancken ◽  
Roland B. Wetzels ◽  
...  
Keyword(s):  
Nursing Home ◽  
Drug Use ◽  
Psychotropic Drug ◽  
Neuropsychiatric Symptoms ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Inappropriate Use ◽  
Psychotropic Drug Use ◽  
Nursing Home Patients ◽  
Sum Score

ABSTRACTBackground:This study explores the appropriateness of psychotropic drug (PD) use for neuropsychiatric symptoms (NPS) in nursing home patients with dementia.Methods:A cross-sectional study on 559 patients with dementia residing on dementia special care units in Dutch nursing homes was conducted. Appropriateness of PD use was assessed using the Appropriate Psychotropic drug use In Dementia (APID) index. The APID index score is calculated using information about individual PDs from patients’ medical records. The index encompasses seven (different) domains of appropriateness, i.e. indication, evaluation, dosage, drug-drug interactions, drug-disease interactions, duplications, and therapy duration.Results:A total of 578 PDs were used for NPS by 60% of the nursing home patients. Indication, evaluation, and therapy duration contributed the most to inappropriate use. Ten per cent of the PDs scored fully appropriate according to the APID index sum score, 36% scored fully appropriate for indication, 46% scored fully appropriate for evaluation, and 58% scored fully appropriate for therapy duration. Antidepressants were used the most appropriately, and antiepileptics the most inappropriately.Conclusions:The minority of the PD use was fully appropriate. The results imply that PD use for NPS in dementia can be improved; the appropriateness should be optimized with a clinical focus on the appropriate indications, evaluations, and therapy duration.

scholarly journals Poverty Dynamics in Lithuania: Persistence, Transitions, Triggers

2015 ◽  
Vol 54 (1) ◽  
pp. 6-17
Author(s):  
Jekaterina Navickė
Keyword(s):  
At Risk ◽  
European Union ◽  
General Population ◽  
Longitudinal Component ◽  
The European Union ◽  
Poverty Dynamics ◽  
Cross Sectional ◽  
Poverty Risk ◽  
Robust Evidence

While Lithuania is among the countries with the highest at-risk-of-poverty rates in the European Union, povertyresearch has so far been dominated by cross-sectional poverty analysis. This paper is aimed at contributing to better understandingof poverty as a dynamic process in Lithuania by examining poverty risk persistence, transitions and triggers. Theanalysis is based on the longitudinal component of the Survey on Income and Living Conditions. The longitudinal at-risk-ofpovertyrate within the four-year panels is estimated to be at around a third of the Lithuanian population within a period of2005–2012. Poverty risk in Lithuania proved to be both widely spread and persistent. The major role of income events forpoverty risk entries and exits highlights the importance of activation into work, especially as concerns secondary householdearners and better income protection in Lithuania. While no robust evidence of poverty penalty was found for poverty exits,the incidence of poverty re-entries within the initial three-year period after poverty exit substantially exceeds poverty entryrates in the general population.

scholarly journals Time trends in depression prevalence among Swedish 85-year-olds: repeated cross-sectional population-based studies in 1986, 2008, and 2015

2021 ◽  
pp. 1-10
Author(s):  
Mattias Jonson ◽  
Robert Sigström ◽  
Khedidja Hedna ◽  
Therese Rydberg Sterner ◽  
Hanna Falk Erhag ◽  
...  
Keyword(s):  
Risk Factors ◽  
Drug Use ◽  
Psychotropic Drug ◽  
Time Trends ◽  
Rating Scale ◽  
Related Factors ◽  
Cross Sectional ◽  
Psychotropic Drug Use ◽  
Prevalence Of Depression ◽  
Health Related

Abstract Background Octogenarians of today are better educated, and physically and cognitively healthier, than earlier born cohorts. Less is known about time trends in mental health in this age group. We aimed to study time trends in the prevalence of depression and psychotropic drug use among Swedish 85-year-olds. Methods We derived data from interviews with 85-year-olds in 1986–1987 (N = 348), 2008–2010 (N = 433) and 2015–17 (N = 321). Depression diagnoses were made according to the Diagnostic and Statistical Manual of Mental Disorders. Symptom burden was assessed with the Montgomery-Åsberg Depression Rating Scale (MADRS). Information on psychotropic drug use, sociodemographic, and health-related factors were collected during the interviews. Results The prevalence of major depression was lower in 2015–2017 (4.7%, p < 0.001) and 2008–2010 (6.9%, p = 0.010) compared to 1986–1987 (12.4%). The prevalence of minor depression was lower in 2015–2017 (8.1%) compared to 2008–2010 (16.2%, p = 0.001) and 1986–1987 (17.8%, p < 0.001). Mean MADRS score decreased from 8.0 in 1986–1987 to 6.5 in 2008–2010, and 5.1 in 2015–2017 (p < 0.001). The reduced prevalence of depression was not explained by changes in sociodemographic and health-related risk factors for depression. While psychoactive drug use was observed in a third of the participants in each cohort, drug type changed over time (increased use of antidepressants and decreased use of anxiolytics and antipsychotics). Conclusions The prevalence of depression in octogenarians has declined during the past decades. The decline was not explained by changes in known risk factors for depression. The present study cannot answer whether changed prescription patterns of psychoactive drugs have contributed to the decline.

scholarly journals A cross-sectional study of psychotropic drug use in the elderly: Consuming patterns, risk factors and potentially inappropriate use

2019 ◽  
pp. ejhpharm-2019-001927
Author(s):  
María Isabel Santos-Pérez ◽  
Inmaculada Fierro ◽  
M Esther Salgueiro-Vázquez ◽  
María Sáinz-Gil ◽  
Luis H Martín-Arias
Keyword(s):  
Risk Factors ◽  
Drug Use ◽  
Psychotropic Drug ◽  
The Elderly ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Inappropriate Use ◽  
Psychotropic Drug Use
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