Autonomy and control in the wish to die in terminally ill patients: A systematic integrative review

2021 ◽  
pp. 1-8
Author(s):  
Andrea Rodríguez-Prat ◽  
Donna M. Wilson ◽  
Remei Agulles
Keyword(s):  
Cultural Context ◽  
Personal Autonomy ◽  
Empirical Studies ◽  
Academic Library ◽  
Integrative Review ◽  
Free Text ◽  
Screening Process ◽  
Mesh Terms ◽  
Wish To Die ◽  
And Control

Abstract Background/Objective Personal autonomy and control are major concepts for people with life-limiting conditions. Patients who express a wish to die (WTD) are often thought of wanting it because of loss of autonomy or control. The research conducted so far has not focused on personal beliefs and perspectives; and little is known about patients’ understanding of autonomy and control in this context. The aim of this review was to analyze what role autonomy and control may play in relation to the WTD expressed by people with life-limiting conditions. Methods A systematic integrative review was conducted. The search strategy used MeSH terms in combination with free-text searching of the EBSCO Discovery Service (which provides access to multiple academic library literature databases, including PubMed and CINAHL), as well as the large PsycINFO, Scopus, and Web of Science library literature databases from their inception until February 2019. The search was updated to January 2021. Results After the screening process, 85 full texts were included for the final analysis. Twenty-seven studies, recording the experiences of 1,824 participants, were identified. The studies were conducted in Australia (n = 5), Canada (n = 5), USA (n = 5), The Netherlands (n = 3), Spain (n = 2), Sweden (n = 2), Switzerland (n = 2), Finland (n = 1), Germany (n = 1), and the UK (n = 1). Three themes were identified: (1) the presence of autonomy for the WTD, (2) the different ways in which autonomy is conceptualized, and (3) the socio-cultural context of research participants. Significance of results Despite the importance given to the concept of autonomy in the WTD discourse, only a few empirical studies have focused on personal interests. Comprehending the context is crucial because personal understandings of autonomy are shaped by socio-cultural–ethical backgrounds and these impact personal WTD attitudes.

scholarly journals The wish to die and hastening death in amyotrophic lateral sclerosis: A scoping review

2021 ◽  
pp. bmjspcare-2020-002640
Author(s):  
Anke Erdmann ◽  
Celia Spoden ◽  
Irene Hirschberg ◽  
Gerald Neitzke
Keyword(s):  
Amyotrophic Lateral Sclerosis ◽  
End Of Life ◽  
Cultural Context ◽  
Final Analysis ◽  
Individual Case ◽  
Screening Process ◽  
Wish To Die ◽  
Death Wishes ◽  
Desire To Die ◽  
Lateral Sclerosis

BackgroundAmyotrophic lateral sclerosis (ALS) develops into a life-threatening condition 2 to 4 years after the onset of symptoms. Although many people with the disease decide in favour of life-sustaining measures, thoughts about hastening death are not uncommon.ObjectivesOur aim was to examine the scope of literature on the wish to die in ALS and provide an insight into determinants and motives for different end-of-life options.MethodsWe searched eight databases for English and German publications on death wishes in ALS for the period from 2008 to 2018 and updated the search up to May 2020. After the screening process, 213 full texts were included for the final analysis. We analysed the texts in MAXQDA, using deductively and inductively generated codes.ResultsWe identified end-of-life considerations, ranging from wishes to die without hastening death, to options with the possibility or intention of hastening death. Besides physical impairment, especially psychosocial factors, socio-demographic status and socio-cultural context have a great impact on decisions for life-shortening options. There is huge variation in the motives and determinants for end-of-life considerations between individuals, different societies, healthcare and legal systems.ConclusionsFor a variety of reasons, the information and counselling provided on different options for sustaining life or hastening death is often incomplete and insufficient. Since the motives and determinants for the wish to hasten death are extremely diverse, healthcare professionals should investigate the reasons, meaning and strength of the desire to die to detect unmet needs and examine which interventions are appropriate in each individual case.

The Role of Leukotrienes Inhibitors in the Management of Chronic Inflammatory Diseases

2020 ◽  
Vol 14 (1) ◽  
pp. 15-31
Author(s):  
Deepak Meshram ◽  
Khushbo Bhardwaj ◽  
Charulata Rathod ◽  
Gail B. Mahady ◽  
Kapil K. Soni
Keyword(s):  
Respiratory Diseases ◽  
Inflammatory Diseases ◽  
Leukotriene B4 ◽  
Published Data ◽  
Free Text ◽  
Plant Origin ◽  
Medical Subject Headings ◽  
Leukotriene Antagonists ◽  
Mesh Terms ◽  
Mediators Of Inflammation

Background: Leukotrienes are powerful mediators of inflammation and interact with specific receptors in target cell membrane to initiate an inflammatory response. Thus, Leukotrienes (LTs) are considered to be potent mediators of inflammatory diseases including allergic rhinitis, inflammatory bowel disease and asthma. Leukotriene B4 and the series of cysteinyl leukotrienes (C4, D4, and E4) are metabolites of arachidonic acid metabolism that cause inflammation. The cysteinyl LTs are known to increase vascular permeability, bronco-constriction and mucus secretion. Objectives: To review the published data for leukotriene inhibitors of plant origin and the recent patents for leukotriene inhibitors, as well as their role in the management of inflammatory diseases. Methods: Published data for leukotrienes antagonists of plant origin were searched from 1938 to 2019, without language restrictions using relevant keywords in both free text and Medical Subject Headings (MeSH terms) format. Literature and patent searches in the field of leukotriene inhibitors were carried out by using numerous scientific databases including Science Direct, PubMed, MEDLINE, Google Patents, US Patents, US Patent Applications, Abstract of Japan, German Patents, European Patents, WIPO and NAPRALERT. Finally, data from these information resources were analyzed and reported in the present study. Results: Currently, numerous anti-histaminic medicines are available including chloropheneremine, brompheniramine, cetirizine, and clementine. Furthermore, specific leukotriene antagonists from allopathic medicines are also available including zileuton, montelukast, pranlukast and zafirlukast and are considered effective and safe medicines as compared to the first generation medicines. The present study reports leukotrienes antagonistic agents of natural products and certain recent patents that could be an alternative medicine in the management of inflammation in respiratory diseases. Conclusion: The present study highlights recent updates on the pharmacology and patents on leukotriene antagonists in the management of inflammation respiratory diseases.

scholarly journals Osteopathic empirical research: a bibliometric analysis from 1966 to 2018

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Chantal Morin ◽  
Isabelle Gaboury
Keyword(s):  
Bibliometric Analysis ◽  
Empirical Research ◽  
Scientific Literature ◽  
Case Reports ◽  
Empirical Studies ◽  
Body Part ◽  
The United States ◽  
Mesh Terms ◽  
Research Designs ◽  
System Body

Abstract Background Despite the increasing use of osteopathy, a manipulative complementary and alternative medicine therapy, in the general population, its efficacy continues to be debated. In this era of evidence-based practice, no studies have previously reviewed the scientific literature in the field to identify published knowledge, trends and gaps in empirical research. The aims of this bibliometric analysis are to describe characteristics of articles published on the efficacy of osteopathic interventions and to provide an overall portrait of their impacts in the scientific literature. Methods A bibliometric analysis approach was used. Articles were identified with searches using a combination of relevant MeSH terms and indexing keywords about osteopathy and research designs in MEDLINE and CINAHL databases. The following indicators were extracted: country of primary author, year of publication, journals, impact factor of the journal, number of citations, research design, participants’ age group, system/body part addressed, primary outcome, indexing keywords and types of techniques. Results A total of 389 articles met the inclusion criteria. The number of empirical studies doubled every 5 years, with the United States, Italy, Spain, and United Kingdom being the most productive countries. Twenty-three articles were cited over 100 times. Articles were published in 103 different indexed journals, but more than half (53.7%) of articles were published in one of three osteopathy-focused readership journals. Randomized control trials (n = 145; 37.3%) and case reports (n = 142; 36.5%) were the most common research designs. A total of 187 (48.1%) studies examined the effects of osteopathic interventions using a combination of techniques that belonged to two or all of the classic fields of osteopathic interventions (musculoskeletal, cranial, and visceral). Conclusion The number of osteopathy empirical studies increased significantly from 1980 to 2014. The productivity appears to be very much in sync with practice development and innovations; however, the articles were mainly published in osteopathic journals targeting a limited, disciplinary-focused readership.

scholarly journals Brain–Computer Interface (BCI) Control of a Virtual Assistant in a Smartphone to Manage Messaging Applications

Sensors ◽  
2021 ◽  
Vol 21 (11) ◽  
pp. 3716
Author(s):  
Francisco Velasco-Álvarez ◽  
Álvaro Fernández-Rodríguez ◽  
Francisco-Javier Vizcaíno-Martín ◽  
Antonio Díaz-Estrella ◽  
Ricardo Ron-Angevin
Keyword(s):  
Free Text ◽  
Short Message ◽  
Negative Consequences ◽  
Computer Interfaces ◽  
Brain Signals ◽  
Message Service ◽  
Performance Results ◽  
And Control ◽  
E Mail ◽  
Visual P300

Brain–computer interfaces (BCI) are a type of assistive technology that uses the brain signals of users to establish a communication and control channel between them and an external device. BCI systems may be a suitable tool to restore communication skills in severely motor-disabled patients, as BCI do not rely on muscular control. The loss of communication is one of the most negative consequences reported by such patients. This paper presents a BCI system focused on the control of four mainstream messaging applications running in a smartphone: WhatsApp, Telegram, e-mail and short message service (SMS). The control of the BCI is achieved through the well-known visual P300 row-column paradigm (RCP), allowing the user to select control commands as well as spelling characters. For the control of the smartphone, the system sends synthesized voice commands that are interpreted by a virtual assistant running in the smartphone. Four tasks related to the four mentioned messaging services were tested with 15 healthy volunteers, most of whom were able to accomplish the tasks, which included sending free text e-mails to an address proposed by the subjects themselves. The online performance results obtained, as well as the results of subjective questionnaires, support the viability of the proposed system.

Indian management research

1983 ◽  
Vol 8 (2) ◽  
pp. 155-176
Keyword(s):  
Financial Management ◽  
Production Management ◽  
Empirical Studies ◽  
Industrial Relations ◽  
Social Science Research ◽  
Science Research ◽  
Environment Policy ◽  
General Management ◽  
Policy And Planning ◽  
And Control

The purpose of these abstracts is to provide reference facilities in the management field. These abstracts have been sponsored by the Indian Council of Social Science Research. These abstracts cover books and articles on empirical studies, experiences of people involved in the management process, and concepts and theories based on Indian data and environment written by Indian or foreign authors and published in India or abroad. The following areas of management are covered: Financial Management, Management Accounting, and Control (FM) Marketing (M) Organization and Administration (OA) Personnel Management and Industrial Relations (PMIR) Production Management, Computers, and Operations Research (PMCOR) General Management: Environment, Policy, and Planning (GM) Policy, Planning, and Development (PPD) Books and articles published after January 1974 are covered in Vikalpa. Abstracts of publications between 1970 and 1973 have been published in two volumes by the Indian Institute of Management, Ahmedabad. For reprint of articles abstracted in Vikalpa please contact the original journals. For further details please write to Professor Shekhar Chaudhuri.

Reported Early Separation Anxiety Symptoms in Patients with Panic and Generalised Anxiety Disorders

1993 ◽  
Vol 27 (3) ◽  
pp. 489-494 ◽  
Author(s):  
Derrick Silove ◽  
Vijaya Manicavasagar ◽  
Dianne O'connell ◽  
Alex Blaszczynski
Keyword(s):  
Risk Factor ◽  
Anxiety Disorder ◽  
Panic Disorder ◽  
Attachment Theory ◽  
Anxiety Symptom ◽  
Separation Anxiety ◽  
Empirical Studies ◽  
Generalised Anxiety Disorder ◽  
Early Separation ◽  
And Control

Attachment theory has proposed that early separation anxiety is a risk factor for adult anxiety disorder, with the recent focus being particularly on panic disorder. The results of empirical studies examining this link are, however, contradictory, possibly because of inconsistencies across studies in measuring memories of early separation anxiety. In the present study, a psychometrically sound measure, the Separation Anxiety Symptom Inventory (SASI) was used to compare memories of such early symptoms in panic disorder (including those with mild phobic-avoidance), generalised anxiety disorder and control subjects. Anxiety patients as a group returned higher SASI scores (p<0.001) with a non-significant trend for panic disorder patients to score higher than those with generalised anxiety. These results suggest that early separation anxiety may be a harbinger of adult anxiety and that risk of panic disorder may be higher in the most severely affected youngsters. As a risk factor, early separation anxiety does not however appear to be uniquely related to adult panic disorder.

scholarly journals CONTRIBUIÇÕES DOS INSTRUMENTOS E TECNOLOGIAS DIGITAIS PARA O MONITORAMENTO E CONTROLE DO DIABETES MELLITUS: REVISÃO INTEGRATIVA / CONTRIBUTIONS OF DIGITAL INSTRUMENTS AND TECHNOLOGIES FOR MONITORING AND CONTROL OF DIABETES MELLITUS: INTEGRATIVE REVIEW

2020 ◽  
Vol 6 (12) ◽  
pp. 99564-99574
Author(s):  
Jaqueline Miranda de Oliveira ◽  
Sandro Percário ◽  
Marcus Vinicius Henriques Brito ◽  
Gisele Carvalho de Oliveira ◽  
Analécia Dâmaris da Silva Alexandre ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Integrative Review ◽  
Monitoring And Control ◽  
Control Of Diabetes ◽  
And Control

scholarly journals Does Socioeconomic Position Affect Knowledge of the Risk Factors and Warning Signs of Stroke in the WHO European Region? A Systematic Literature Review

2020 ◽  
Author(s):  
Katie Stack ◽  
Wendy Robertson ◽  
Clare Blackburn
Keyword(s):  
Risk Factors ◽  
Socioeconomic Position ◽  
Stroke Risk ◽  
Educational Interventions ◽  
Warning Signs ◽  
European Region ◽  
Free Text ◽  
Stroke Risk Factors ◽  
Mesh Terms ◽  
Increasing Knowledge

Abstract Background: Strokes are one of the leading causes of death worldwide. People with a lower socioeconomic position (SEP) (i.e. with regards to education, income and occupation) are at a higher risk of having a stroke and have worse clinical outcomes compared to the general population. Good knowledge levels about stroke risk factors and warning signs are key to prolonging life and reducing health issues caused by stroke. This systematic review examined differences in knowledge of stroke risk factors and warning signs with regards to SEP in the WHO European region. Methods: MEDLINE, Embase, Web of Science, PsycINFO and CINAHL were systematically searched using appropriate Medical Subject Headings (MeSH) terms and free text, combining search terms with Boolean operators. Two independent reviewers selected studies in two stages (title and abstract, and full-text), and screened reference lists of included studies. Only studies in English and based in the WHO European region were included. Results: Screening identified 2,118 records. In the final review, 20 articles were included, with 67,309 study participants between them. Out of 17 studies that looked at stroke risk factors, 11 found increasing knowledge to be associated with higher SEP, four found no difference by SEP, one showed a mixed pattern and one outlier study found increasing knowledge of risk factors to be associated with a lower SEP. Out of 19 studies that looked at stroke warning signs or symptoms, 15 found there to be better knowledge of warning signs with a higher SEP, three found there to be no difference, and the same outlier study found increasing knowledge of warning signs with a lower SEP. Studies that seemed to have a higher quality rating found increasing knowledge of stroke with a higher SEP. A meta-analysis was not possible due to heterogeneity of studies. Conclusions: In the WHO European region, better knowledge of stroke risk factors and warning signs is associated with a higher SEP. Public health campaigns and educational interventions aiming to increase stroke knowledge should be targeted at people with a lower SEP.

scholarly journals What is Right? What is Wrong? and Does the Answer Tell Something about Culture? - an Investigation into Culture and Morality Using the Values Concept

2021 ◽  
Author(s):  
◽  
Christin-Melanie Vauclair
Keyword(s):  
Cultural Values ◽  
Cultural Context ◽  
Convergent Validity ◽  
Personal Values ◽  
Empirical Studies ◽  
Moral Values ◽  
Value Theory ◽  
Cross Cultural ◽  
Macro Level ◽  
Multilevel Regression

<p>Morality, or what is considered right or wrong, varies seemingly across cultures. However, the literature shows that moral psychologists have mainly investigated moral reasoning assuming a universal morality. Cross-cultural psychologists in contrast have widely neglected moral issues such as prescriptive beliefs of what people ought to do in a culture, and have predominantly measured culture through personal values. This thesis attempts to bridge this gap by focusing on the values concept. Four empirical studies were conducted to critically examine values as a measure of culture and their relationship to morality. Chapter one is an introduction into the topics morality, culture and values. Chapter two outlines the conceptual and methodological issues associated with deriving cultural values through the statistical aggregation of individuals' personal values. A value taxonomy is presented in which personal moral values and societal moral values are proposed as alternatives for measuring the cultural context. Following this critique, personal values are examined in two empirical studies in a cross-cultural context scrutinizing the validity of Schwartz' (1994) Culture-level Value Theory. Study 1 is a cross-cultural meta-analysis using the Rokeach Value Survey (Rokeach, 1973) showing that Schwartz' culture-level value structure was replicable with different samples, and a different method for assessing value priorities. Nonetheless, a set of values not included in Schwartz' analysis formed a new value type: Self-fulfilled Connectedness (SFC) which is related to the pursuit of non-material goals and endorsed in countries in which basic needs are fulfilled. Study 2 tested in a multilevel regression model whether Schwartz' cultural values predicted individuals' moral attitudes with data from more than 40 different countries. The findings indicated that the value dimension Autonomy-Embeddedness explained individuals' lenient attitude towards personal-sexual, but not towards dishonest-illegal issues. Study 3 dealt with the fundamental critique raised in chapter two that Schwartz (1994) does not operationalize micro- and macro-level constructs independently when measuring cultural values. To address this empirically, personal moral values and societal moral values were explicitly measured in student samples from eight cultures. Societal moral values showed greater cross-cultural differences than personal moral values. Furthermore, societal moral values at the culture-level conceptually replicated the multilevel findings from Study 2. This suggests that societal moral values are a valid macro-level variable for the measurement of culture. Finally, Study 4 was conducted to elicit implicit moral values. Respondents from four cultures free-listed their associations of a 'moral person'. correspondence analyses revealed that collectivistic-oriented samples mentioned more traditional moral attributes, whereas individualistic samples reported more liberal attributes. Furthermore, accessibility of implicit moral values - matched with the SVS - correlated with explicit ratings of personal moral values from Study 3, providing convergent validity for this kind of values. This multi-method finding corroborated that personal moral values and societal moral values are different concepts. In sum, these studies support the validity of Schwartz' theory and suggest that notions of right and wrong do indeed tell us something about culture, but it depends on (1) the issues studied (personal-sexual issues), and (2) the kind of values measured (societal moral values).</p>

scholarly journals Computer-based nursing education: An integrative review of empirical studies

2012 ◽  
Vol 2 (3) ◽  
Author(s):  
Juan Manuel Carrillo de Gea ◽  
José Luis Fernández Alemán ◽  
Ana Belén Sánchez García
Keyword(s):  
Nursing Education ◽  
Empirical Studies ◽  
Integrative Review ◽  
Computer Based
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