Identification of Unusual Bacterial Glycosylation by Tandem Mass Spectrometry Analyses of Intact Proteins

2005 ◽  
Vol 77 (23) ◽  
pp. 7774-7782 ◽  
Author(s):  
Michael Schirm ◽  
Ian C. Schoenhofen ◽  
Susan M. Logan ◽  
Karen C. Waldron ◽  
Pierre Thibault
Keyword(s):  
Mass Spectrometry ◽  
Tandem Mass Spectrometry ◽  
Tandem Mass ◽  
Intact Proteins ◽  
Bacterial Glycosylation

scholarly journals Robust Two-Dimensional Separation of Intact Proteins for Bottom-Up Tandem Mass Spectrometry of the Human CSF Proteome

2012 ◽  
Vol 11 (6) ◽  
pp. 3143-3149 ◽  
Author(s):  
Adriana Bora ◽  
Carol Anderson ◽  
Muznabanu Bachani ◽  
Avindra Nath ◽  
Robert J. Cotter
Keyword(s):  
Mass Spectrometry ◽  
Tandem Mass Spectrometry ◽  
Tandem Mass ◽  
Two Dimensional ◽  
Bottom Up ◽  
Intact Proteins

Tandem Mass Spectrometry of Intact Proteins for Characterization of Biomarkers fromBacilluscereusTSpores

2001 ◽  
Vol 73 (23) ◽  
pp. 5725-5731 ◽  
Author(s):  
Plamen A. Demirev ◽  
Javier Ramirez ◽  
Catherine Fenselau
Keyword(s):  
Mass Spectrometry ◽  
Tandem Mass Spectrometry ◽  
Tandem Mass ◽  
Intact Proteins

scholarly journals Using TDFragMapper: a high-performance tool to assess experimental parameters in top-down proteomics

2021 ◽  
Author(s):  
Diogo Borges Lima ◽  
Jonathan Dhenin ◽  
Mathieu Dupré ◽  
Julia Chamot-Rooke
Keyword(s):  
Mass Spectrometry ◽  
Tandem Mass Spectrometry ◽  
Software Tool ◽  
Intact Protein ◽  
Tandem Mass ◽  
Top Down ◽  
Experimental Conditions ◽  
Intact Proteins ◽  
Fragment Ions ◽  
Experimental Parameters

Abstract Here we present a new software-tool for visualizing fragment ions and sequence coverage of intact proteins in top-down mass spectrometry. TDFragMapper combines the data arising from multiple and diverse tandem mass spectrometry experiments of intact proteins. Our tool maps fragment ions onto the protein backbone sequence and allows for a rapid comparison of the results obtained when varying experimental parameters in tandem mass spectrometry (MS/MS) experiments of intact proteins: fragmentation method, selected precursor charge state, activation level, technical replicate. In summary, TDFragMapper is a unique software-tool that allows an easy selection of the best experimental conditions leading to the highest confidence in intact protein sequence identification.

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