Hierarchical Porous Fluorinated Graphene Oxide@Metal–Organic Gel Composite: Label-Free Electrochemical Aptasensor for Selective Detection of Thrombin

2018 ◽  
Vol 10 (48) ◽  
pp. 41089-41097 ◽  
Author(s):  
Veronika Urbanová ◽  
Kolleboyina Jayaramulu ◽  
Andreas Schneemann ◽  
Štěpán Kment ◽  
Roland A. Fischer ◽  
...  
2021 ◽  
pp. 1-10
Author(s):  
F. Jahangiri-Dehaghani ◽  
H.R. Zare ◽  
Z. Shekari

A label-free electrochemical aptasensor was constructed for the sensitive and selective determination of AFM1. For preparation of the aptasensor, the AFM1 aptamer was immobilised on the surface of a glassy carbon electrode modified with hemin encapsulated in Fe-based metal-organic frameworks (hemin@Fe-MIL-101). The morphology and the structure of Fe-MIL-101 and hemin@Fe-MIL-101 were evaluated by scanning electron microscopy, Fourier-transform infrared spectroscopy, X-ray powder diffraction and Brunauer-Emmett-Teller-N2 sorption methods. Electrochemical impedance spectroscopy and cyclic voltammetry were performed to monitor the fabrication process of the electrochemical aptasensor. The electrochemical reduction current of hemin encapsulated in Fe-MIL-101 serves as a signal for the quantitative determination of AFM1. Differential pulse voltammetry was done to determine the AFM1 concentration in the linear range of 1.0×10-1-100.0 ng/ml. The detection limit of AFM1 was estimated to be 4.6×10-2 ng/ml. Finally, the fabricated aptasensor was applied to determine AFM1 in raw and boiled milk samples.


2019 ◽  
Vol 6 (4) ◽  
pp. 045601 ◽  
Author(s):  
Hao Li ◽  
Genliang Hou ◽  
Qi Tian ◽  
Song Bi ◽  
Zhaohui Liu ◽  
...  

2012 ◽  
Vol 116 (49) ◽  
pp. 25955-25961 ◽  
Author(s):  
Panit Chantharasupawong ◽  
Reji Philip ◽  
Narayanan T. Narayanan ◽  
Parambath M. Sudeep ◽  
Akshay Mathkar ◽  
...  

RSC Advances ◽  
2016 ◽  
Vol 6 (52) ◽  
pp. 46037-46047 ◽  
Author(s):  
A. Maio ◽  
D. Giallombardo ◽  
R. Scaffaro ◽  
A. Palumbo Piccionello ◽  
I. Pibiri

An easy method to selectively introduce specific fluorotails into a graphene oxide–silica nanohybrid. Fluoro-functionalization increases the oxygen exchange at saturation.


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