Immobilization of Thermostable Maltogenic Amylase fromBacillus stearothermophilusfor Continuous Production of Branched Oligosaccharides

1997 ◽  
Vol 45 (10) ◽  
pp. 4168-4172 ◽  
Author(s):  
Gil-Jin Kang ◽  
Myo-Jeong Kim ◽  
Jeong-Weon Kim ◽  
Kwan Hwa Park
Keyword(s):  
Continuous Production ◽  
Maltogenic Amylase

Systematic selection of shift plans for continuous production with the aid of work-physiological criteria

1976 ◽  
Author(s):  
Peter Knauth ◽  
Walter Rohmert ◽  
Joseph Rutenfranz
Keyword(s):  
Continuous Production ◽  
Systematic Selection ◽  
Selection Of

OPERATION OF EQUIPMENT IN CONTINUOUS PRODUCTION

2020 ◽  
Author(s):  
Сергей Ильдусович Валеев
Keyword(s):  
Continuous Production ◽  
Subsequent Development

В работе проведен анализ возможной эксплуатации сосудов и аппаратов с дефектами типа расслоение. Установлено, что эксплуатация оборудования возможна только с последующей разработкой мероприятий, позволяющих повысить уровень безопасности. The paper analyzes the possible operation of vessels and apparatuses with defects of the stratification type. It was established that the operation of the equipment is possible only with the subsequent development of measures to increase the level of safety.

Respect for the Environment is Part of Competitiveness - Best Available Technology Applied to an Old Pulp Mill at Kaskinen

1999 ◽  
Vol 40 (11-12) ◽  
pp. 201-206
Author(s):  
I. Reilama ◽  
N. Ilomäki
Keyword(s):  
Process Development ◽  
Continuous Production ◽  
Production Capacity ◽  
Pulp Mill ◽  
Process Technology ◽  
Line Production ◽  
Nutrient Emissions ◽  
Best Available Technology ◽  
Available Technology ◽  
Process Solutions

Oy Metsä-Botnia Ab's Kaskinen mill produces ECF and TCF bleached softwood and hardwood pulp on a single continuous production line. Production capacity has been raised from 250,000 tonnes to 420,000 tonnes a year after the commission in 1977. The basic process solutions date mainly from the 1970s. However, process technology has been gradually modernised. With systematic and well-timed process development investments the mill has remained competitive and among frontrunners in terms of environmental protection. Today, Kaskinen represent the best available technology (BAT) applicable to old mills. Effluent loading in general and nutrient emissions in particular has diminished during the development projects of the mill. Comparison to other mills shows that as far as effluent emissions are concerned, Kaskinen is one of the best pulp mills in Finland and Scandinavia. In this presentation, Kaskinen is also compared to Metsä-Rauma, the first greenfield TCF mill in the world, which was started up in 1996. Kaskinen's pioneering work on TCF technology was used as a basis for process solutions in the Rauma greenfield project.

Continuous production of a chiral amine in a packed bed reactor with co-immobilized amine dehydrogenase and formate dehydrogenase

2021 ◽  
Vol 407 ◽  
pp. 127065
Author(s):  
Robert D. Franklin ◽  
Joshua A. Whitley ◽  
Adam A. Caparco ◽  
Bettina R. Bommarius ◽  
Julie A. Champion ◽  
...  
Keyword(s):  
Formate Dehydrogenase ◽  
Continuous Production ◽  
Packed Bed ◽  
Packed Bed Reactor ◽  
Chiral Amine ◽  
Amine Dehydrogenase

Continuous production of NbN on carbon fibres by magnetron sputtering

Cryogenics ◽  
1984 ◽  
Vol 24 (11) ◽  
pp. 636-638 ◽  
Author(s):  
M. Dietrich ◽  
L.J. Paterok
Keyword(s):  
Magnetron Sputtering ◽  
Continuous Production ◽  
Carbon Fibres

scholarly journals Homogenous overexpression of the extracellular matrix protein Netrin-1 in a hollow fiber bioreactor

2021 ◽  
Author(s):  
Aniel Moya-Torres ◽  
Monika Gupta ◽  
Fabian Heide ◽  
Natalie Krahn ◽  
Scott Legare ◽  
...  
Keyword(s):  
Extracellular Matrix ◽  
Hollow Fiber ◽  
Mammalian Cells ◽  
Matrix Protein ◽  
Continuous Production ◽  
Extracellular Matrix Protein ◽  
Close Monitoring ◽  
High Quality ◽  
Biolayer Interferometry ◽  
Hollow Fiber Bioreactor

Abstract The production of recombinant proteins for functional and biophysical studies, especially in the field of structural determination, still represents a challenge as high quality and quantities are needed to adequately perform experiments. This is in part solved by optimizing protein constructs and expression conditions to maximize the yields in regular flask expression systems. Still, work flow and effort can be substantial with no guarantee to obtain improvements. This study presents a combination of workflows that can be used to dramatically increase protein production and improve processing results, specifically for the extracellular matrix protein Netrin-1. This proteoglycan is an axon guidance cue which interacts with various receptors to initiate downstream signaling cascades affecting cell differentiation, proliferation, metabolism, and survival. We were able to produce large glycoprotein quantities in mammalian cells, which were engineered for protein overexpression and secretion into the media using the controlled environment provided by a hollow fiber bioreactor. Close monitoring of the internal bioreactor conditions allowed for stable production over an extended period of time. In addition to this, Netrin-1 concentrations were monitored in expression media through biolayer interferometry which allowed us to increase Netrin-1 media concentrations tenfold over our current flask systems while preserving excellent protein quality and in solution behavior. Our particular combination of genetic engineering, cell culture system, protein purification, and biophysical characterization permitted us to establish an efficient and continuous production of high-quality protein suitable for structural biology studies that can be translated to various biological systems. Key points • Hollow fiber bioreactor produces substantial yields of homogenous Netrin-1 • Biolayer interferometry allows target protein quantitation in expression media • High production yields in the bioreactor do not impair Netrin-1 proteoglycan quality Graphical abstract

Pre-hydrogenation stage as a strategy to improve the continuous production of a diesel-like biofuel from palm oil

2021 ◽  
Vol 168 ◽  
pp. 505-515
Author(s):  
Juan I. del Río ◽  
William Pérez ◽  
Fernando Cardeño ◽  
James Marín ◽  
Luis A. Rios
Keyword(s):  
Palm Oil ◽  
Continuous Production
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