Reactive pocket epithelium in untreated chronic periodontal disease: possible derivation from developmental remnants of the enamel organ and root sheath

2001 ◽  
Vol 30 (3) ◽  
pp. 178-186 ◽  
Author(s):  
Neil Hunter ◽  
Brent Nicholls ◽  
Mukesh Srivastava ◽  
Cheryl C. Chapple ◽  
Hans F. Zoellner ◽  
...  
Keyword(s):  
Periodontal Disease ◽  
Enamel Organ ◽  
Root Sheath ◽  
Chronic Periodontal Disease

scholarly journals Relation between chronic periodontal disease and plasmatic levels of triglycerides, total cholesterol and fractions

2005 ◽  
Vol 19 (4) ◽  
pp. 284-289 ◽  
Author(s):  
Ana Cristina Posch Machado ◽  
Maria Rozeli de Souza Quirino ◽  
Luiz Fernando Costa Nascimento
Keyword(s):  
Periodontal Disease ◽  
Total Cholesterol ◽  
Blood Lipid ◽  
Oral Disease ◽  
Whole Body ◽  
Lipid Levels ◽  
Periodontal Infection ◽  
Chronic Periodontal Disease ◽  
Systemic Health ◽  
Blood Lipid Levels

Many people in the world are affected by hyperlipidemia, which is a known risk factor for atherosclerotic disease. On the other hand, periodontitis, a prevalent oral disease, has been connected to several systemic health changes, including an altered lipid metabolism. Transient and recurrent bacteremias, which may be caused by periodontal infection, induce an intense local and systemic inflammatory response, leading to changes in the whole body. The aim of the present study was to verify the relationship between severe and moderate periodontal disease and blood lipid levels. Sixty individuals seen at the clinics of the University of Taubaté, São Paulo, over 20 years old, were divided into two groups, with and without periodontitis, and paired according to sex and age. Their levels of total cholesterol, tryglicerides and fractions were determined. Variables related to high cholesterol levels, including age, sex and body mass index, were evaluated. The values recommended by the Brazilian Society of Cardiology were considered to classify lipidemia. The results showed that mean levels of cholesterol (192.1 mg/dl ± 40.9) and triglycerides (153.5 mg/dl ± 105.6) in individuals with periodontitis were higher than, but not statistically different from, those of individuals without periodontitis (186.1 mg/dl ± 35.4 and 117.5 mg/dl ± 68, respectively). Therefore, this study has demonstrated that there is no significant relationship between periodontal disease, regardless of its intensity, and blood lipid levels in the studied population.

scholarly journals Association between chronic periodontal disease and cardiovascular risk factor hyperlipidemia

2014 ◽  
Vol 3 (4) ◽  
pp. 249 ◽  
Author(s):  
Anitha Akkaloori ◽  
Parthasarathi Parthasarathi ◽  
MohammadShakeel Anjum ◽  
Praveen Gadde ◽  
Monica Mocherla ◽  
...  
Keyword(s):  
Risk Factor ◽  
Cardiovascular Risk ◽  
Periodontal Disease ◽  
Cardiovascular Risk Factor ◽  
Chronic Periodontal Disease

Genetic susceptibility to chronic periodontal disease

2002 ◽  
Vol 4 (11) ◽  
pp. 1157-1167 ◽  
Author(s):  
Pamela J. Baker ◽  
Derry C. Roopenian
Keyword(s):  
Periodontal Disease ◽  
Genetic Susceptibility ◽  
Chronic Periodontal Disease

scholarly journals Oxidative stress in chronic periodontitis patients with type II diabetes mellitus

2018 ◽  
Vol 12 (02) ◽  
pp. 225-231 ◽  
Author(s):  
Ruby Ramya Vincent ◽  
Devapriya Appukuttan ◽  
Dhayanand John Victor ◽  
Aruna Balasundaram
Keyword(s):  
Oxidative Stress ◽  
Diabetes Mellitus ◽  
Periodontal Disease ◽  
Diabetic Patients ◽  
Clinical Parameters ◽  
Type Ii ◽  
Chronic Periodontal Disease ◽  
Significant Difference ◽  
The Mean ◽  
Group 1

ABSTRACT Objective: Oxidative stress (OS) refers to the disequilibrium between free radicals and antioxidant defense mechanisms and is significantly implicated in the pathogenesis of chronic degenerative and inflammatory diseases such as chronic periodontal disease (CP) and diabetes mellitus (DM). This study aimed to evaluate the total antioxidants capacity (TAOC) and total oxidants status (TOS) in the gingival crevicular fluid (GCF) in CP participants with type II DM. Materials and Methods: A total of 80 participants were allotted into four groups as follows: Group 1: Generalized CP (GCP) without type II DM (n = 20); Group 2: GCP with type II DM (n = 20); Group 3: Type II DM without CP (n = 20); and Group 4: Systemically and periodontally healthy (PH) (n = 20). Clinical parameters such as plaque index, gingival index, probing pocket depth, and clinical attachment level were recorded. Pooled GCF was collected followed by the estimation of TAOC, TOS, and OS index (OSI) using Erel O Colorimetric analysis. Results: The clinical parameters recorded showed the statistically significant difference (P < 0.001) between the groups. The mean TAOC value was the highest in PH group. The mean TOS and OSI were higher in Group 1, 2, and 3 participants when compared to the PH participants. All the biochemical parameters evaluated showed a statistically significant difference (P < 0.001) between groups. Conclusions: The study further validates the use of OSI as a marker for periodontal disease activity and emphasizes the role of OS in the pathogenesis of Type II diabetic patients with the chronic periodontal disease.

scholarly journals Antimicrobial photodynamic chemotherapy mediated by PapaMBlue on chronic periodontal disease

Medicine ◽  
2020 ◽  
Vol 99 (6) ◽  
pp. e18854
Author(s):  
Giuliana Giovinazzo Anselmo ◽  
Ana Carolina Alves Camargo Tortamano ◽  
Marcela Letícia Leal Gonçalves ◽  
Adriana Leal-Rossi ◽  
Bianca Aparecida Godoy-Miranda ◽  
...  
Keyword(s):  
Periodontal Disease ◽  
Chronic Periodontal Disease

Mouse Molar Dentin Size/Shape is Dependent on Growth Hormone Status

2007 ◽  
Vol 86 (5) ◽  
pp. 463-468 ◽  
Author(s):  
J.R. Smid ◽  
J.E. Rowland ◽  
W.G. Young ◽  
K.T. Coschigano ◽  
J.J. Kopchick ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Enamel Organ ◽  
Tooth Crown ◽  
Crown Width ◽  
Morphogenetic Protein ◽  
Root Sheath ◽  
Dentin Matrix ◽  
Dentin Thickness ◽  
Gh Excess ◽  
Gh Receptors

Growth hormone (GH) status affects dental development, but how GH influences tooth size/shape is unclear. Since GH affects dental epithelial proliferation, we hypothesized that GH influences the tooth crown and root dimensions. Dentin matrix dimensions were measured in longitudinal sections of decalcified first mandibular molars from 3 genetically modified mice: giant (GH-Excess) mice and dwarf (GH-Antagonist and GH-Receptor-Knockout) mice. GH status was found to influence crown width, root length, and dentin thickness. Analysis of these data suggests that GH influences both tooth crown and root development prior to dentinogenesis as well as during appositional growth of dentin. This is concordant with the expression of paracrine GH and GH receptors during tooth bud morphogenesis, and of GH receptors in the enamel organ, dental papilla, and Hertwig’s epithelial root sheath during dentinogenesis. Based on prior studies, these GH morphogenetic actions may be mediated by the induction of both bone morphogenetic protein and insulin-like growth factor-1 expression.

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