Interventions for students with autism in inclusive settings: A best-evidence synthesis and meta-analysis.

2019 ◽  
Vol 145 (5) ◽  
pp. 490-507 ◽  
Author(s):  
Laci Watkins ◽  
Katherine Ledbetter-Cho ◽  
Mark O'Reilly ◽  
Lucy Barnard-Brak ◽  
Pau Garcia-Grau
Keyword(s):  
Evidence Synthesis ◽  
Meta Analysis ◽  
Best Evidence Synthesis ◽  
Inclusive Settings ◽  
Students With Autism

scholarly journals Recalibrating the risk of hamstring strain injury (HSI): A 2020 systematic review and meta-analysis of risk factors for index and recurrent hamstring strain injury in sport

2020 ◽  
Vol 54 (18) ◽  
pp. 1081-1088 ◽  
Author(s):  
Brady Green ◽  
Matthew N Bourne ◽  
Nicol van Dyk ◽  
Tania Pizzari
Keyword(s):  
Risk Factors ◽  
Systematic Review ◽  
Evidence Synthesis ◽  
Meta Analysis ◽  
Significant Risk ◽  
Older Age ◽  
Future Research ◽  
Hamstring Strain ◽  
Best Evidence Synthesis ◽  
History Of

ObjectiveTo systematically review risk factors for hamstring strain injury (HSI).DesignSystematic review update.Data sourcesDatabase searches: (1) inception to 2011 (original), and (2) 2011 to December 2018 (update). Citation tracking, manual reference and ahead of press searches.Eligibility criteria for selecting studiesStudies presenting prospective data evaluating factors associated with the risk of index and/or recurrent HSI.MethodSearch result screening and risk of bias assessment. A best evidence synthesis for each factor and meta-analysis, where possible, to determine the association with risk of HSI.ResultsThe 78 studies captured 8,319 total HSIs, including 967 recurrences, in 71,324 athletes. Older age (standardised mean difference=1.6, p=0.002), any history of HSI (risk ratio (RR)=2.7, p<0.001), a recent HSI (RR=4.8, p<0.001), previous anterior cruciate ligament (ACL) injury (RR=1.7, p=0.002) and previous calf strain injury (RR=1.5, p<0.001) were significant risk factors for HSI. From the best evidence synthesis, factors relating to sports performance and match play, running and hamstring strength were most consistently associated with HSI risk. The risk of recurrent HSI is best evaluated using clinical data and not the MRI characteristics of the index injury.Summary/conclusionOlder age and a history of HSI are the strongest risk factors for HSI. Future research may be directed towards exploring the interaction of risk factors and how these relationships fluctuate over time given the occurrence of index and recurrent HSI in sport is multifactorial.

scholarly journals The Role of Lateral Extra-articular Tenodesis in Primary Anterior Cruciate Ligament Reconstruction: A Systematic Review With Meta-analysis and Best-Evidence Synthesis

2017 ◽  
Vol 5 (10) ◽  
pp. 232596711773176 ◽  
Author(s):  
Brian M. Devitt ◽  
Stuart W. Bell ◽  
Clare L. Ardern ◽  
Taylor Hartwig ◽  
Tabitha J. Porter ◽  
...  
Keyword(s):  
Ligament Reconstruction ◽  
Pivot Shift ◽  
Evidence Synthesis ◽  
Cruciate Ligament ◽  
Meta Analysis ◽  
Cruciate Ligament Reconstruction ◽  
Significant Difference ◽  
Best Evidence Synthesis ◽  
Anterior Cruciate

Background: The role of lateral extra-articular tenodesis (LEAT) to augment primary anterior cruciate ligament reconstruction (ACLR) remains controversial. Purpose: To determine whether the addition of LEAT to primary ACLR provides greater control of rotational laxity and improves clinical outcomes compared with ACLR alone and to assess the impact of early versus delayed ACLR. Study Design: Systematic review; Level of evidence, 3. Methods: Two reviewers independently searched 7 databases for randomized and nonrandomized clinical studies comparing ACLR plus LEAT versus ACLR alone. Animal, cadaveric, and biomechanical studies; revision or repair procedures; and studies using synthetic ligaments and multiligamentous-injured knees were excluded. Risk of bias was assessed with a modified Downs and Black checklist. The primary outcome was postoperative pivot shift. These data were pooled by use of a fixed-effects meta-analysis model. The studies were divided into delayed (>12 months) and early (≤12 months) reconstruction groups for meta-analysis. A best-evidence synthesis was performed on the remaining outcome measures. Results: Of 387 titles identified, 11 articles were included (5 of high quality). Meta-analysis of postoperative pivot shift in 3 studies of delayed primary ACLR showed a statistically significant difference for the pivot-shift test in favor of ACLR with LEAT (odds ratio [OR], 0.44; 95% confidence interval [CI], 0.24-0.81; P = .008; I2 = 0). Meta-analysis of 5 studies of early primary ACLR found no statistically significant difference with the addition of LEAT (OR, 0.60; 95% CI, 0.33-1.09; P = .10; I2 = 33%). Insufficient evidence was available to determine whether the addition of LEAT had any effect on clinical, objective, subjective, and functional outcomes. Conclusion: In primary ACLR, no evidence is available showing additional benefit of LEAT in reducing the postoperative pivot shift in early reconstructions (≤12 months); however, LEAT may have a role in delayed ACLR. Strong evidence exists that a combined ACLR and LEAT reduces lateral femoral translation, but there is insufficient evidence to identify any benefit for other clinical outcomes.

scholarly journals Musculoskeletal pain and sedentary behaviour in occupational and non-occupational settings: a systematic review with meta-analysis

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Francis Q. S. Dzakpasu ◽  
Alison Carver ◽  
Christian J. Brakenridge ◽  
Flavia Cicuttini ◽  
Donna M. Urquhart ◽  
...  
Keyword(s):  
Systematic Review ◽  
Shoulder Pain ◽  
Evidence Synthesis ◽  
Meta Analysis ◽  
Insufficient Evidence ◽  
Cross Sectional ◽  
Experimental Intervention ◽  
Best Evidence Synthesis ◽  
Cross Sectional Studies ◽  
Full Day

Abstract Background Sedentary behaviour (SB; time spent sitting) is associated with musculoskeletal pain (MSP) conditions; however, no prior systematic review has examined these associations according to SB domains. We synthesised evidence on occupational and non-occupational SB and MSP conditions. Methods Guided by a PRISMA protocol, eight databases (MEDLINE, CINAHL, PsycINFO, Web of Science, Scopus, Cochrane Library, SPORTDiscus, and AMED) and three grey literature sources (Google Scholar, WorldChat, and Trove) were searched (January 1, 2000, to March 17, 2021) for original quantitative studies of adults ≥ 18 years. Clinical-condition studies were excluded. Studies’ risk of bias was assessed using the QualSyst checklist. For meta-analyses, random effect inverse-variance pooled effect size was estimated; otherwise, best-evidence synthesis was used for narrative review. Results Of 178 potentially-eligible studies, 79 were included [24 general population; 55 occupational (incuding15 experimental/intervention)]; 56 studies were of high quality, with scores > 0.75. Data for 26 were meta-synthesised. For cross-sectional studies of non-occupational SB, meta-analysis showed full-day SB to be associated with low back pain [LBP – OR = 1.19(1.03 – 1.38)]. Narrative synthesis found full-day SB associations with knee pain, arthritis, and general MSP, but the evidence was insufficient on associations with neck/shoulder pain, hip pain, and upper extremities pain. Evidence of prospective associations of full-day SB with MSP conditions was insufficient. Also, there was insufficient evidence on both cross-sectional and prospective associations between leisure-time SB and MSP conditions. For occupational SB, cross-sectional studies meta-analysed indicated associations of self-reported workplace sitting with LBP [OR = 1.47(1.12 – 1.92)] and neck/shoulder pain [OR = 1.73(1.46 – 2.03)], but not with extremities pain [OR = 1.17(0.65 – 2.11)]. Best-evidence synthesis identified inconsistent findings on cross-sectional association and a probable negative prospective association of device-measured workplace sitting with LBP-intensity in tradespeople. There was cross-sectional evidence on the association of computer time with neck/shoulder pain, but insufficient evidence for LBP and general MSP. Experimental/intervention evidence indicated reduced LBP, neck/shoulder pain, and general MSP with reducing workplace sitting. Conclusions We found cross-sectional associations of occupational and non-occupational SB with MSP conditions, with occupational SB associations being occupation dependent, however, reverse causality bias cannot be ruled out. While prospective evidence was inconclusive, reducing workplace sitting was associated with reduced MSP conditions. Future studies should emphasise prospective analyses and examining potential interactions with chronic diseases. Protocol registration PROSPERO ID #CRD42020166412 (Amended to limit the scope)

scholarly journals Intervention for Children with Developmental Coordination Disorder: A Systematic Review

2007 ◽  
Author(s):  
Susan Hillier
Keyword(s):  
Developmental Coordination Disorder ◽  
Negative Impact ◽  
Evidence Synthesis ◽  
Meta Analysis ◽  
Specific Content ◽  
Intervention Delivery ◽  
Best Evidence Synthesis ◽  
Underlying Mechanisms ◽  
Coordination Disorder ◽  
Variable Quality

Prevalence of children with developmental coordination disorder (DCD) is high (6-13% of all school children) and the negative impact of their movement difficulties on their participation in recreation and academic pursuits is well documented. This secondary research systematically reviewed the available literature for evidence of effectiveness of interventions that aim to improve the movement capability of children with DCD. Specified databases were searched for appropriate studies, these were retrieved and two reviewers appraised the level and quality of evidence. Thirty one studies were included between levels I and III-3 of the NH & MRC protocol. Scoring using an established critical appraisal tool demonstrated variable quality. Meta-analysis was not possible due to the clinical heterogeneity of the primary studies. A best evidence synthesis of results was conducted, producing clear evidence that no intervention has poor results when compared to any intervention. The high number of purportedly different interventions and variable quality make definitive conclusions about the merits of specific approaches difficult. There may be generic qualities or factors in the studied interventions that are more important for effectiveness than specific content. More information is needed on the underlying mechanisms of DCD, factors influencing effectiveness and the broader pragmatics of intervention delivery.

scholarly journals 144 Is proximal stability a risk factor for knee injuries in athletic populations? A systematic review with meta-analysis and best-evidence synthesis

2021 ◽  
Author(s):  
Lionel Chia ◽  
Danilo De Oliveira Silva ◽  
Marnee McKay ◽  
Justin Sullivan ◽  
Fabio Mıcolis de Azevedo ◽  
...  
Keyword(s):  
Systematic Review ◽  
Risk Factor ◽  
Evidence Synthesis ◽  
Meta Analysis ◽  
Knee Injuries ◽  
Best Evidence Synthesis

scholarly journals Outcomes of platelet-rich plasma for plantar fasciopathy: a best-evidence synthesis

2020 ◽  
Vol 15 (1) ◽  
Author(s):  
Tao Yu ◽  
Jiang Xia ◽  
Bing Li ◽  
Haichao Zhou ◽  
Yunfeng Yang ◽  
...  
Keyword(s):  
Functional Outcomes ◽  
Platelet Rich Plasma ◽  
Evidence Synthesis ◽  
Meta Analysis ◽  
Cochrane Library ◽  
Common Disease ◽  
Double Blind ◽  
Plantar Fasciopathy ◽  
Best Evidence Synthesis ◽  
Significant Superiority

Abstract Background Plantar fasciopathy (PF) is a very common disease, affecting about 1/10 people in their lifetime. Platelet-rich plasma (PRP) had been demonstrated to be useful in achieving helpful effects for plantar fasciopathy. The purpose of this study was to compare the pain and functional outcomes between PRP and corticosteroid (CS) or placebo for plantar fasciopathy through meta-analysis and provide the best evidence. Methods Literature was searched systematically to explore related studies that were published in Cochrane Library, PubMed, Embase, Medline, SpringerLink, OVID, and ClinicalTrials.gov. Articles regarding comparative research about the outcomes of PRP therapy and CS or placebo injection were selected. Data of pain and functional outcomes was extracted and imported into Reviewer Manager 5.3 to analyze. Results Thirteen RCTs were included and analyzed. Analysis results showed significant superiority of PRP in outcome scores when compared with CS (VAS: MD = − 0.85, P < 0.0001, I2 = 85%; AOFAS: MD = 10.05, P < 0.0001, I2 = 85%), whereas there is no statistical difference in well-designed double-blind trials (VAS: MD = 0.15, P = 0.72, I2 = 1%; AOFAS: MD = 2.71, P = 0.17, I2 = 0%). In the comparison of the PRP and the placebo, the pooled mean difference was − 3.76 (P < 0.0001, 95% CI = − 4.34 to − 3.18). Conclusions No superiority of PRP had been found in well-designed double-blind studies, whereas it is implied that the outcomes of PRP are better than placebo based on available evidence.

scholarly journals Is sarcopenia associated with anxiety symptoms and disorders? A systematic review and meta-analysis protocol

BMJ Open ◽  
2021 ◽  
Vol 11 (11) ◽  
pp. e054125
Author(s):  
Emma C West ◽  
Lana J Williams ◽  
Kayla B Corney ◽  
Julie A Pasco
Keyword(s):  
Evidence Synthesis ◽  
Meta Analysis ◽  
Published Data ◽  
Adverse Health Outcomes ◽  
Study Selection ◽  
Best Evidence Synthesis ◽  
Ethical Approval ◽  
Registration Number ◽  
And Performance ◽  
And Function

IntroductionSarcopenia is a skeletal muscle disorder characterised by a progressive decline in muscle mass and function (strength and performance). Sarcopenia is associated with numerous adverse health outcomes and has recently been linked to neurological and psychiatric disorders, including dementia and depression. Whether sarcopenia is related to other common psychiatric illnesses, such as anxiety, is unclear. We aim to systematically identify and review the extant literature regarding the association between sarcopenia and anxiety symptomatology and/or disorders (anxiety) in adults.Methods and analysisWe will conduct a systematic search across four online databases (CINAHL, Embase, MEDLINE Complete and PsycINFO) from inception to September 2021. Two reviewers will independently confirm study selection and assess methodological quality of included studies. If possible, a meta-analysis will be performed to determine pooled OR for the relationship between sarcopenia and anxiety. If meta-analysis is not possible due to methodological heterogeneity a ‘best evidence synthesis’ will be performed.Ethics and disseminationThis review will use published data only, thus, ethical approval will not be required. Findings will be published in a peer-reviewed journal and presented at conferences.PROSPERO registration numberCRD42020209420.

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