Musculoskeletal pain and sedentary behaviour in occupational and non-occupational settings: a systematic review with meta-analysis

Abstract Background Sedentary behaviour (SB; time spent sitting) is associated with musculoskeletal pain (MSP) conditions; however, no prior systematic review has examined these associations according to SB domains. We synthesised evidence on occupational and non-occupational SB and MSP conditions. Methods Guided by a PRISMA protocol, eight databases (MEDLINE, CINAHL, PsycINFO, Web of Science, Scopus, Cochrane Library, SPORTDiscus, and AMED) and three grey literature sources (Google Scholar, WorldChat, and Trove) were searched (January 1, 2000, to March 17, 2021) for original quantitative studies of adults ≥ 18 years. Clinical-condition studies were excluded. Studies’ risk of bias was assessed using the QualSyst checklist. For meta-analyses, random effect inverse-variance pooled effect size was estimated; otherwise, best-evidence synthesis was used for narrative review. Results Of 178 potentially-eligible studies, 79 were included [24 general population; 55 occupational (incuding15 experimental/intervention)]; 56 studies were of high quality, with scores > 0.75. Data for 26 were meta-synthesised. For cross-sectional studies of non-occupational SB, meta-analysis showed full-day SB to be associated with low back pain [LBP – OR = 1.19(1.03 – 1.38)]. Narrative synthesis found full-day SB associations with knee pain, arthritis, and general MSP, but the evidence was insufficient on associations with neck/shoulder pain, hip pain, and upper extremities pain. Evidence of prospective associations of full-day SB with MSP conditions was insufficient. Also, there was insufficient evidence on both cross-sectional and prospective associations between leisure-time SB and MSP conditions. For occupational SB, cross-sectional studies meta-analysed indicated associations of self-reported workplace sitting with LBP [OR = 1.47(1.12 – 1.92)] and neck/shoulder pain [OR = 1.73(1.46 – 2.03)], but not with extremities pain [OR = 1.17(0.65 – 2.11)]. Best-evidence synthesis identified inconsistent findings on cross-sectional association and a probable negative prospective association of device-measured workplace sitting with LBP-intensity in tradespeople. There was cross-sectional evidence on the association of computer time with neck/shoulder pain, but insufficient evidence for LBP and general MSP. Experimental/intervention evidence indicated reduced LBP, neck/shoulder pain, and general MSP with reducing workplace sitting. Conclusions We found cross-sectional associations of occupational and non-occupational SB with MSP conditions, with occupational SB associations being occupation dependent, however, reverse causality bias cannot be ruled out. While prospective evidence was inconclusive, reducing workplace sitting was associated with reduced MSP conditions. Future studies should emphasise prospective analyses and examining potential interactions with chronic diseases. Protocol registration PROSPERO ID #CRD42020166412 (Amended to limit the scope)

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Isokinetic Dynamometry as a Tool to Predict Shoulder Injury in an Overhead Athlete Population: A Systematic Review

Sports ◽

10.3390/sports8090124 ◽

2020 ◽

Vol 8 (9) ◽

pp. 124

Author(s):

Andrea Bagordo ◽

Kimberly Ciletti ◽

Kevin Kemp-Smith ◽

Vini Simas ◽

Mike Climstein ◽

...

Keyword(s):

Systematic Review ◽

Outcome Measures ◽

External Rotation ◽

Evidence Synthesis ◽

Peak Torque ◽

Shoulder Injury ◽

Isokinetic Dynamometry ◽

Cross Sectional ◽

Best Evidence Synthesis ◽

Cross Sectional Studies

Prospective and cross-sectional studies have used pre-season isokinetic dynamometry strength and endurance measurements of shoulder internal rotation (IR) and external rotation (ER) to determine if they can be correlated to injury. However, to date, no review has provided a synthesis of all available literature on this topic. The aim of this systematic review was to identify isokinetic dynamometry studies that assess shoulder IR and ER strength and endurance in the overhead athletic population in relation to shoulder injury. Electronic databases (PubMed, CINAHL, and SportDiscus) were searched through September 2019 using pre-determined search terms. Both prospective and cross-sectional studies were included in this review. Studies were assessed for quality using either Appraisal Tool for Cross-sectional Studies (AXIS) or Critical Appraisal Skills Programme (CASP). Data on outcome measures of strength and endurance peak torque (PT) and ratios (ER:IR) were extracted and further analysed using a best evidence synthesis approach. A total of 13 articles met the inclusion criteria. Conflicting evidence was found when reviewing all studies without differentiating by study type. Prospective study designs revealed strong evidence that reduced IR endurance and reduced strength ratios are predictive of shoulder injury. Cross-sectional literature showed only conflicting and limited evidence for all outcome measures. At this stage, more research is needed in individual sporting populations using prospective cohort designs.

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P3-097: SHORTENED VERSIONS OF MONTREAL COGNITIVE ASSESSMENT (MOCA) ARE FEASIBLE FOR SCREENING OF MILD COGNITIVE IMPAIRMENT AND DEMENTIA: A SYSTEMATIC REVIEW AND META-ANALYSIS OF 33 CROSS-SECTIONAL STUDIES

Alzheimer s & Dementia ◽

10.1016/j.jalz.2019.06.3124 ◽

2019 ◽

Vol 15 ◽

pp. P962-P966

Author(s):

Joyce YC. Chan ◽

Kelvin KF. Tsoi ◽

Tak Kit Chan ◽

Adrian Wong ◽

Timothy CY. Kwok ◽

...

Keyword(s):

Systematic Review ◽

Cognitive Impairment ◽

Mild Cognitive Impairment ◽

Cognitive Assessment ◽

Meta Analysis ◽

Montreal Cognitive Assessment ◽

Cross Sectional ◽

Cross Sectional Studies

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Knowledge of blood donation and associated factors in Ethiopia: a systematic review and meta-analysis

BMJ Open ◽

10.1136/bmjopen-2020-044343 ◽

2021 ◽

Vol 11 (7) ◽

pp. e044343

Author(s):

Addisu Getie ◽

Adam Wondmieneh ◽

Melaku Bimerew ◽

Getnet Gedefaw ◽

Asmamaw Demis

Keyword(s):

Systematic Review ◽

Associated Factors ◽

Blood Donation ◽

Meta Analysis ◽

Educational Status ◽

Sensitivity Analyses ◽

Cross Sectional ◽

Level Of Knowledge ◽

Cross Sectional Studies ◽

Study Participants

ObjectiveTo assess the level of knowledge about blood donation and associated factors in Ethiopia.DesignSystematic review and meta-analysis.MethodsBoth published and unpublished cross-sectional studies on the level of knowledge about blood donation in Ethiopia were included. Articles from different databases such as PubMed/MEDLINE, HINARI, EMBASE, Scopus, Google Scholar and African Journals Online were searched. Cochrane I2 statistics were used to check for heterogeneity. Subgroup and sensitivity analyses of evidence of heterogeneity were carried out. Egger’s test with funnel plot was conducted to investigate publication bias.ResultTwenty cross-sectional studies with a total of 8338 study participants (4712 men and 3626 women) were included. The overall nationwide level of knowledge about blood donation was 56.57% (95% CI 50.30 to 62.84). Being in secondary school and above (adjusted OR=3.12; 95% CI 2.34 to 4.16) and being male (adjusted OR=1.81; 95% CI 1.44 to 2.28) were the factors associated with level of knowledge about blood donation.ConclusionMore than half of the study participants were knowledgeable about blood donation. Sex and educational status were the factors significantly associated with level of knowledge about blood donation in Ethiopia. Therefore, there is a need for education and dissemination of information about blood donation among the general population to build adequate knowledge and maintain regular blood supply.

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Inflammatory biomarkers in older adults with frailty: a systematic review and meta-analysis of cross-sectional studies

Aging Clinical and Experimental Research ◽

10.1007/s40520-021-02022-7 ◽

2022 ◽

Author(s):

YuShuang Xu ◽

MengMeng Wang ◽

Di Chen ◽

Xin Jiang ◽

ZhiFan Xiong

Keyword(s):

Systematic Review ◽

Older Adults ◽

Meta Analysis ◽

Inflammatory Biomarkers ◽

Cross Sectional ◽

Cross Sectional Studies

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Vitamin D deficiency and depression in adults: systematic review and meta-analysis

The British Journal of Psychiatry ◽

10.1192/bjp.bp.111.106666 ◽

2013 ◽

Vol 202 (2) ◽

pp. 100-107 ◽

Cited By ~ 342

Author(s):

Rebecca E. S. Anglin ◽

Zainab Samaan ◽

Stephen D. Walter ◽

Sarah D. McDonald

Keyword(s):

Systematic Review ◽

Vitamin D ◽

Vitamin D Deficiency ◽

Randomised Controlled Trials ◽

Meta Analysis ◽

Controlled Trials ◽

Cross Sectional ◽

Cross Sectional Studies ◽

Randomised Controlled ◽

The Relationship

BackgroundThere is conflicting evidence about the relationship between vitamin D deficiency and depression, and a systematic assessment of the literature has not been available.AimsTo determine the relationship, if any, between vitamin D deficiency and depression.MethodA systematic review and meta-analysis of observational studies and randomised controlled trials was conducted.ResultsOne case-control study, ten cross-sectional studies and three cohort studies with a total of 31 424 participants were analysed. Lower vitamin D levels were found in people with depression compared with controls (SMD = 0.60,95% Cl 0.23–0.97) and there was an increased odds ratio of depression for the lowest v. highest vitamin D categories in the cross-sectional studies (OR = 1.31, 95% CI 1.0–1.71). The cohort studies showed a significantly increased hazard ratio of depression for the lowest v. highest vitamin D categories (HR=2.21, 95% CI 1.40–3.49).ConclusionsOur analyses are consistent with the hypothesis that low vitamin D concentration is associated with depression, and highlight the need for randomised controlled trials of vitamin D for the prevention and treatment of depression to determine whether this association is causal.

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Candida Coinfection among Patients with Pulmonary tuberculosis in the World; A Systematic Review and Meta-analysis of Cross-Sectional Studies

10.21203/rs.2.14804/v1 ◽

2019 ◽

Author(s):

Mehran Ghazalibina ◽

Ali Shakerimoghaddam ◽

Azad Khaledi

Keyword(s):

Systematic Review ◽

Pulmonary Tuberculosis ◽

Fungal Infections ◽

Secondary Infection ◽

Meta Analysis ◽

High Rate ◽

Candida Spp ◽

Cross Sectional ◽

Cross Sectional Studies ◽

Early Diagnose

Abstract Background Diagnosis of fungal co-infections in patients with pulmonary tuberculosis has critical importance. In this review, we aimed to determine the prevalence of candida coinfection in patients with pulmonary tuberculosis.Methods The present systematic review of cross-sectional studies was conducted based on the Preferred Reporting Items for Systematic reviews and Meta-analysis (PRISMA) Protocol. Studies published online in English from January 2001 to March 2019 were assessed. Literature search was performed in Web of Science, MEDLINE/PubMed, and Scopus databases using keywords combinations of “pulmonary fungal”, “pulmonary coinfection”, OR “pulmonary mycosis”, “pulmonary fungal infections/agents”, OR “polymicrobial infection”, OR “secondary infection”, OR “mixed infections”, “pulmonary candidiasis”, “fungi coinfection”, “fungal co-colonization”, AND “pulmonary tuberculosis”, OR “pulmonary TB”. Data was analyzed using Comprehensive Meta-Analysis software. Heterogeneity between studies was evaluated by Cochran's Q, and I 2 tests.Results The pooled global prevalence of candida coinfection among patients with pulmonary tuberculosis was 25.7% (95% CI: 23.7-27.9). C. albicans was the most prevalent Candida spp. with a pooled prevalence of 65.8% (95% CI: 54.3-75.7). Risk factors of candida coinfection included smoking, diabetes, advanced age, and low body mass index.Conclusion The present review showed the high rate of candida coinfection among patients suffering from pulmonary tuberculosis. Adequate measures are necessary to early diagnose and treat these infections.

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Dairy food consumption is associated with a lower risk of the metabolic syndrome and its components: a systematic review and meta-analysis

British Journal Of Nutrition ◽

10.1017/s0007114518001460 ◽

2018 ◽

Vol 120 (4) ◽

pp. 373-384 ◽

Cited By ~ 21

Author(s):

Mijin Lee ◽

Hanna Lee ◽

Jihye Kim

Keyword(s):

Systematic Review ◽

Metabolic Syndrome ◽

Food Consumption ◽

Lower Risk ◽

Meta Analysis ◽

Cross Sectional ◽

Dairy Food ◽

Dairy Foods ◽

The Metabolic Syndrome ◽

Cross Sectional Studies

AbstractA systematic review and a meta-analysis of observational studies were performed to assess the dose–response relationship between specific types of dairy foods and the risk of the metabolic syndrome (MetS) and its components. Studies of dairy foods and the risk of the MetS and its components published up to June 2016 were searched using PubMed, EMBASE and a reference search. Random-effects models were used to estimate the pooled relative risks (RR) with 95 % CI. Finally, ten cross-sectional studies, two nested case–control studies and twenty-nine cohort studies were included for the analysis. In a dose–response analysis of cohort studies and cross-sectional studies, the pooled RR of the MetS for a one-serving/d increment of total dairy food (nine studies) and milk (six studies) consumption (200 g/d) were 0·91 (95 % CI 0·85, 0·96) and 0·87 (95 % CI 0·79, 0·95), respectively. The pooled RR of the MetS for yogurt (three studies) consumption (100 g/d) was 0·82 (95 % CI 0·73, 0·91). Total dairy food consumption was associated with lower risk of MetS components, such as hyperglycaemia, elevated blood pressure, hypertriacylglycerolaemia and low HDL- cholesterol. A one-serving/d increment of milk was related to a 12 % lower risk of abdominal obesity, and a one-serving/d increment of yogurt was associated with a 16 % lower risk of hyperglycaemia. These associations were not significantly different by study design, study location or adjustment factors. This meta-analysis showed that specific types of dairy food consumption such as milk and yogurt as well as total dairy food consumption were inversely related to risk of the MetS and its components.

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Psychosis in children of separated parents: A systematic review and meta-analysis

European Psychiatry ◽

10.1192/j.eurpsy.2019.15 ◽

2020 ◽

Vol 63 (1) ◽

Author(s):

Luis Ayerbe ◽

María Pérez-Piñar ◽

Quintí Foguet-Boreu ◽

Salma Ayis

Keyword(s):

Systematic Review ◽

Odds Ratio ◽

Psychotic Disorders ◽

Meta Analysis ◽

Childhood Adversity ◽

Case Control ◽

Parental Separation ◽

Cross Sectional ◽

Increased Risk ◽

Cross Sectional Studies

Abstract Background. Parental separation is a very common childhood adversity. The association between other adverse childhood experiences and an increased risk of psychosis has been reported. However, the evidence on the risk of psychosis for children of separated parents is limited. In this systematic review, cohort, case–control, and cross-sectional studies, comparing the risk of psychotic disorders for people with and without separated parents, were searched, critically appraised, and summarized. Methods. Studies were searched in PubMed, EMBASE, PsycINFO, and the Web of Science, from database inception to September 2019. A meta-analysis, using random-effects models, was undertaken to obtain pooled estimates of the risk of psychosis among participants with separated parents. Results. Twelve studies, with 305,652 participants from 22 countries, were included in the review. A significantly increased risk of psychosis for those with separated parents was observed, with a pooled odds ratio: 1.53 (95% confidence interval [CI]: 1.29–1.76), p < 0.001. The association remained significant when cohort, case–control, and cross-sectional studies were analyzed separately. The five cohort studies included in this review showed and increased risk of psychosis with odds ratio: 1.47 (95% CI: 1.26–1.69), p < 0.001. Conclusions. Parental separation is a common childhood adversity associated with an increased risk of psychosis. Although the risk for an individual child of separated parents is still low, given the high proportion of couple that separate, the increased rates of psychosis may be substantial in the population. Further studies on the risk of psychosis in those with separated parents, and the explanatory factors for this association, are required.

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