scholarly journals Blood plasma metabolic profiling of pregnant women with antenatal depressive symptoms

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Hanna E. Henriksson ◽  
Christina Malavaki ◽  
Emma Bränn ◽  
Vasilis Drainas ◽  
Susanne Lager ◽  
...  
Keyword(s):  
Depressive Symptoms ◽  
Blood Plasma ◽  
Pregnant Women ◽  
Metabolic Profiling ◽  
Antenatal Depressive Symptoms

scholarly journals The pregnancy intention to have a second child and antenatal depressive symptoms in Chinese women under the new two-child-per-couple policy

2019 ◽  
Author(s):  
Meili Xiao ◽  
Bing Fu ◽  
Chunmei Mi ◽  
Chen Pan ◽  
Shujuan Zhu ◽  
...  
Keyword(s):  
Depressive Symptoms ◽  
Pregnant Women ◽  
Edinburgh Postnatal Depression Scale ◽  
Chinese Women ◽  
Depression Scale ◽  
Pregnancy Intention ◽  
Key Words Pregnancy ◽  
Second Child ◽  
Logistic Regression Models ◽  
Antenatal Depressive Symptoms

Abstract Background: Few studies investigated the association between the pregnancy intention to have a second child and antenatal depressive symptoms.The aim of this study was to explore the association between the pregnancy intention to have a second child by pregnant women’s own desires, pregnant women’s husband own desires, parents who want to grandchild desires, couple’s concordance desires and antenatal depressive symptoms. Methods: A total of 306 participants who completed questionnaire were included in our analysis. Antenatal depressive symptom was assessed using the Chinese version of Edinburgh Postnatal Depression Scale. Logistic regression models were used to estimate the association between the pregnancy intention to have a second child by pregnant women’s own desires, pregnant women’s husband own desires, parents who want to grandchild desires and antenatal depressive symptoms. Results: the prevalence of antenatal depressive symptoms was 36.3% among the second child pregnant women. Of the 306 participants, the proportion of the pregnancy intention to have a second child by pregnant women’s own desires, pregnant women’s husband desires, parents who want to grandchild desires and couple’s concordance desires was 8.5%, 8.5%, 10.8% and 72.2% respectively. Compared with the pregnancy intention by couple’s concordance desires, pregnant women’s own desires to have a second child had higher risk of antenatal depressive symptoms after adjustment for potential confounders (OR=4.560, 95%CI: 1.603,12.973). No association was found between the pregnancy intention to have a second child by pregnant women’s husband own desires, parents who want to grandchild desires and antenatal depressive symptoms after adjustment for confounders (OR=1.996, 95%CI:0.781,5.105; OR=0.744, 95%CI: 0.306,1.811, respectively). Conclusion: These findings suggest the pregnancy intention to have a second child by pregnant women own’s desires may be a risk factors for antenatal depressive symptoms among two-child pregnant women. A qualitative study should be carried out to investigate the real reason for the intention by pregnant women’s own desires and antenatal depressive symptoms in the future, because of this study was a quantitative study. Key words: pregnancy intention; antenatal depressive symptoms; second child

scholarly journals The association between social support and antenatal depressive and anxiety symptoms among Australian women

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Asres Bedaso ◽  
Jon Adams ◽  
Wenbo Peng ◽  
David Sibbritt
Keyword(s):  
Social Support ◽  
Depressive Symptoms ◽  
Social Interaction ◽  
Pregnant Women ◽  
Anxiety Symptoms ◽  
Considerable Proportion ◽  
Informational Support ◽  
Antenatal Depressive Symptoms ◽  
Positive Social Interaction ◽  
Antenatal Anxiety

Abstract Background Antenatal depression and antenatal anxiety adversely affect several obstetric and foetal outcomes, and increase the rate of postnatal mental illness. Thus, to tackle these challenges the need for social support during pregnancy is vital. However, an extensive literature search failed to show a published study on the relationship between domains of social support and antenatal depressive, as well as antenatal anxiety symptoms in Australia. This study examined the association between domains of social support and antenatal depressive and anxiety symptoms among Australian women. Methods The current study used data obtained from the 1973–78 cohort of the Australian Longitudinal Study on Women’s Health (ALSWH), focusing upon women who reported being pregnant (n = 493). Depression and anxiety were assessed using the 10 item Center for Epidemiological Studies Depression (CES-D-10) scale, and the 9-item Goldberg Anxiety and Depression scale (GADS) respectively. The 19 item-Medical Outcomes Study Social Support index (MOSS) was used to assess social support. A logistic regression model was used to examine the associations between domains of social support and antenatal depressive and anxiety symptoms after adjusting for potential confounders. Result The current study found 24.7 and 20.9% of pregnant women screened positive for depressive and anxiety symptoms respectively. After adjusting for potential confounders, our study found that the odds of antenatal depressive symptoms was about four and threefold higher among pregnant women who reported low emotional/informational support (AOR = 4.75; 95% CI: 1.45, 15.66; p = 0.010) and low social support (overall support) (AOR = 3.26; 95%CI: 1.05, 10.10, p = 0.040) respectively compared with their counterpart. In addition, the odds of antenatal anxiety symptoms was seven times higher among pregnant women who reported low affectionate support/positive social interaction (AOR = 7.43; 95%CI: 1.75, 31.55; p = 0.006). Conclusion A considerable proportion of pregnant Australian women had depressive symptoms and/or anxiety symptoms, which poses serious health concerns. Low emotional/informational support and low affectionate support/positive social interaction have a significant association with antenatal depressive and anxiety symptoms respectively. As such, targeted screening of expectant women for social support is essential.

scholarly journals Changes in Depressive Symptoms During the Antenatal Period: A Cohort Study from Bangladesh

2020 ◽  
Vol 42 (6) ◽  
pp. 519-524
Author(s):  
Musammet Rasheda Begum ◽  
Soma Chowdhury Biswas
Keyword(s):  
Depressive Symptoms ◽  
Pregnant Women ◽  
Associated Factors ◽  
Family Income ◽  
Depression Scale ◽  
Well Being ◽  
First Trimester ◽  
Antenatal Clinic ◽  
Antenatal Depressive Symptoms ◽  
Mean Differences

Background: Antenatal depressive symptoms adversely affect the health and well-being of women, babies, and their families. This study aimed to explore the prevalence and probable associated factors of depressivse symptoms. Methods: A prospective cohort approach was adopted, and 435 pregnant women were assessed longitudinally at an antenatal clinic in the first, second, and third trimesters. Edinburgh Postnatal Depression Scale (EPDS) was used to measure self-reported depressive symptoms. The multivariate approach of the general linear model was used to evaluate the mean differences of depression scores among the trimesters. To investigate the associated factors of depressive symptoms, generalized estimating equation (GEE) was used to take into account the clustering effect. Results: More than half (58.13%) of the pregnant women had antenatal depressive symptoms in at least one trimester. Depressive symptoms decreased throughout the pregnancy; they were higher in the first trimester and declined toward the third trimester. Significant mean differences were found in depression scores among the three trimesters. GEE showed that trimester, education, family income, and body mass index (BMI) are significantly associated with antenatal depressive symptoms. Conclusions: First trimester is the most critical period for identification of depressive symptoms. At-risk women need to be treated. Proper education achievement, economic solvency, and adequate nutrition could reduce the depressive symptoms.

scholarly journals Antenatal Depressive Symptoms and Associated Risk Factors among Pregnant Women

2019 ◽  
Vol 58 (4) ◽  
pp. 346
Author(s):  
Seung Jae Baek ◽  
Ji-ae Yun ◽  
Ji ae Nam ◽  
Eun Young Seo ◽  
Seo Young Kwon ◽  
...  
Keyword(s):  
Risk Factors ◽  
Depressive Symptoms ◽  
Pregnant Women ◽  
Antenatal Depressive Symptoms ◽  
Associated Risk Factors

Mindfulness, Self-compassion And Depressive Symptoms In Pregnant Women

2016 ◽  
Vol 33 (S1) ◽  
pp. S420-S420 ◽  
Author(s):  
A.T. Pereira ◽  
S. Xavier ◽  
E. Bento ◽  
J. Azevedo ◽  
M. Marques ◽  
...  
Keyword(s):  
Depressive Symptoms ◽  
Postpartum Depression ◽  
Pregnant Women ◽  
Child Outcomes ◽  
Self Report ◽  
Common Humanity ◽  
Self Compassion ◽  
Antenatal Depressive Symptoms ◽  
Acting With Awareness ◽  
In Pregnancy

IntroductionDepressive symptoms in pregnancy are risk factors for postpartum depression and associated to adverse child outcomes (Glover, 2014). Depressive symptoms decreases after participation in mindfulness and self-compassion based interventions for pregnant women (e.g. Goodman et al., 2014). However, apart from intervention trials, there are not studies on the relationship between mindfulness, self-compassion and depressive symptoms in pregnancy (Zoeterman, 2014).ObjectiveTo explore the association between mindfulness, self-compassion and depressive symptoms in pregnant women.MethodsFour hundred and twenty-seven pregnant women (mean age: 32.56 ± 4.785 years) in their second trimester of pregnancy completed a set of self-report questionnaires validated for pregnancy: Facets of Mindfulness Questionnaire-10 ([FMQ-10]; Azevedo et al., 2015; to evaluate Nonjudging of experience/NJ, acting with awareness (AA) and observing and describing (OD), Self-Compassion Scale ([SCS]; Bento et al., 2015; to evaluate self-kindness, self-judgment, common humanity [CH], isolation, mindfulness and over-identification [OD]) and Postpartum Depression Screening Scale-24 (PDSS-24; Pereira et al., 2013). Only variables significantly correlated with the outcomes were entered in the multiple regression models.ResultsFMQ-10 and SCS Total scores were both significant predictors of PDSS-24 (B = –0.294,–0.272). Derealization and failure predictors were NJ and Isolation (B = –0.234; 0.384); Suicidal ideation predictor was NJ, OD and isolation (B = –0.152;–0.115; 0.334); concentration difficulties and anxiety predictors were isolation and CH (B = 0.296;–0.201); Sleep difficulties predictors were AA and isolation (B = –0.199; 0.248) (all P < 0.05).ConclusionsMindfulness and self-Ccompassion dimensions, particularly nonjudging of experience, acting with awareness, observing and describing are protective correlates of antenatal depressive symptoms. Isolation is a correlate of PD in pregnancy.Disclosure of interestThe authors have not supplied their declaration of competing interest.

scholarly journals Antenatal depressive symptoms among pregnant women: Evidence from a Southern Brazilian population-based cohort study

2017 ◽  
Vol 209 ◽  
pp. 140-146 ◽  
Author(s):  
Carolina de Vargas Nunes Coll ◽  
Mariângela Freitas da Silveira ◽  
Diego Garcia Bassani ◽  
Elena Netsi ◽  
Fernando César Wehrmeister ◽  
...  
Keyword(s):  
Cohort Study ◽  
Depressive Symptoms ◽  
Pregnant Women ◽  
Population Based ◽  
Brazilian Population ◽  
Antenatal Depressive Symptoms

scholarly journals Metabolic Profiling Indicates Diversity in the Metabolic Physiologies Associated With Maternal Postpartum Depressive Symptoms

2021 ◽  
Vol 12 ◽  
Author(s):  
Emma Bränn ◽  
Christina Malavaki ◽  
Emma Fransson ◽  
Maria-Konstantina Ioannidi ◽  
Hanna E. Henriksson ◽  
...  
Keyword(s):  
Depressive Symptoms ◽  
Metabolic Profiling ◽  
Edinburgh Postnatal Depression Scale ◽  
Depression Scale ◽  
Gas Chromatography Mass Spectrometry ◽  
Future Studies ◽  
Postpartum Depressive Symptoms ◽  
Antenatal Depressive Symptoms ◽  
Edge Method ◽  
Hydroxybutanoic Acid

Background: Postpartum depression (PPD) is a devastating disease requiring improvements in diagnosis and prevention. Blood metabolomics identifies biological markers discriminatory between women with and those without antenatal depressive symptoms. Whether this cutting-edge method can be applied to postpartum depressive symptoms merits further investigation.Methods: As a substudy within the Biology, Affect, Stress, Imagine and Cognition Study, 24 women with PPD symptom (PPDS) assessment at 6 weeks postpartum were included. Controls were selected as having a score of ≤ 6 and PPDS cases as ≥12 on the Edinburgh Postnatal Depression Scale. Blood plasma was collected at 10 weeks postpartum and analyzed with gas chromatography–mass spectrometry metabolomics.Results: Variations of metabolomic profiles within the PPDS samples were identified. One cluster showed altered kidney function, whereas the other, a metabolic syndrome profile, both previously associated with depression. Five metabolites (glycerol, threonine, 2-hydroxybutanoic acid, erythritol, and phenylalanine) showed higher abundance among women with PPDSs, indicating perturbations in the serine/threonine and glycerol lipid metabolism, suggesting oxidative stress conditions.Conclusions: Alterations in certain metabolites were associated with depressive pathophysiology postpartum, whereas diversity in PPDS physiologies was revealed. Hence, plasma metabolic profiling could be considered in diagnosis and pathophysiological investigation of PPD toward providing clues for treatment. Future studies require standardization of various subgroups with respect to symptom onset, lifestyle, and comorbidities.

Sign in / Sign up

Export Citation Format

Share Document