scholarly journals Association of cytosolic sialidase Neu2 with plasma membrane enhances Fas-mediated apoptosis by impairing PI3K-Akt/mTOR-mediated pathway in pancreatic cancer cells

2018 ◽  
Vol 9 (2) ◽  
Author(s):  
Shalini Nath ◽  
Chhabinath Mandal ◽  
Uttara Chatterjee ◽  
Chitra Mandal
2020 ◽  
Vol 31 (12) ◽  
pp. 1259-1272 ◽  
Author(s):  
Casey J. Latario ◽  
Lori W. Schoenfeld ◽  
Charles L. Howarth ◽  
Laura E. Pickrell ◽  
Fatema Begum ◽  
...  

We identify tumor microtubes (TMTs) and cell-substrate protrusions (CSPs) in a pancreatic cancer line, in cell culture, tumor models, and a subset of primary human tumors. TMTs and CSPs emanate from the lateral plasma membrane and contain actin filaments, microtubules, and cytokeratin. Arp2/3 complex drives two distinct TMT assembly mechanisms.


2015 ◽  
Vol 290 (41) ◽  
pp. 24760-24771 ◽  
Author(s):  
Andrew D. James ◽  
Waseema Patel ◽  
Zohra Butt ◽  
Magretta Adiamah ◽  
Raga Dakhel ◽  
...  

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