scholarly journals Context-dependent regulation of endothelial cell metabolism: differential effects of the PPARβ/δ agonist GW0742 and VEGF-A

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Ashton Faulkner ◽  
Eleanor Lynam ◽  
Robert Purcell ◽  
Coleen Jones ◽  
Colleen Lopez ◽  
...  
Keyword(s):  
Endothelial Cell ◽  
Cell Metabolism ◽  
Differential Effects ◽  
Context Dependent ◽  
Endothelial Cell Metabolism

scholarly journals Laminar Shear Stress Inhibits Endothelial Cell Metabolism via KLF2-Mediated Repression of PFKFB3

2015 ◽  
Vol 35 (1) ◽  
pp. 137-145 ◽  
Author(s):  
Anuradha Doddaballapur ◽  
Katharina M. Michalik ◽  
Yosif Manavski ◽  
Tina Lucas ◽  
Riekelt H. Houtkooper ◽  
...  
Keyword(s):  
Shear Stress ◽  
Endothelial Cell ◽  
Cell Metabolism ◽  
Laminar Shear Stress ◽  
Laminar Shear ◽  
Endothelial Cell Metabolism

ENMET: Endothelial Cell Metabolism Mathematical Model

2009 ◽  
Author(s):  
Gianni Orsi ◽  
Carmelo De Maria ◽  
Federico Vozzi ◽  
Mariangela Guzzardi ◽  
Arti Ahluwalia ◽  
...  
Keyword(s):  
Mathematical Model ◽  
Endothelial Cell ◽  
Cell Metabolism ◽  
Endothelial Cell Metabolism

scholarly journals The Role of High-Density Lipoproteins in Endothelial Cell Metabolism and Diabetes-Impaired Angiogenesis

2020 ◽  
Vol 21 (10) ◽  
pp. 3633 ◽  
Author(s):  
Khalia R. Primer ◽  
Peter J. Psaltis ◽  
Joanne T.M. Tan ◽  
Christina A. Bursill
Keyword(s):  
Endothelial Cell ◽  
Cell Metabolism ◽  
High Density ◽  
Metabolic Reprogramming ◽  
High Density Lipoproteins ◽  
Impaired Wound Healing ◽  
Endothelial Cell Function ◽  
Positive Effects ◽  
Impaired Angiogenesis ◽  
Endothelial Cell Metabolism

Diabetes mellitus affects millions of people worldwide and is associated with devastating vascular complications. A number of these complications, such as impaired wound healing and poor coronary collateral circulation, are characterised by impaired ischaemia-driven angiogenesis. There is increasing evidence that high-density lipoproteins (HDL) can rescue diabetes-impaired angiogenesis through a number of mechanisms, including the modulation of endothelial cell metabolic reprogramming. Endothelial cell metabolic reprogramming in response to tissue ischaemia is a driver of angiogenesis and is dysregulated by diabetes. Specifically, diabetes impairs pathways that allow endothelial cells to upregulate glycolysis in response to hypoxia adequately and impairs suppression of mitochondrial respiration. HDL rescues the impairment of the central hypoxia signalling pathway, which regulates these metabolic changes, and this may underpin several of its known pro-angiogenic effects. This review discusses the current understanding of endothelial cell metabolism and how diabetes leads to its dysregulation whilst examining the various positive effects of HDL on endothelial cell function.

Influence of nutrients and cytokines on endothelial cell metabolism.

1994 ◽  
Vol 13 (3) ◽  
pp. 224-231 ◽  
Author(s):  
B Hennig ◽  
J N Diana ◽  
M Toborek ◽  
C J McClain
Keyword(s):  
Endothelial Cell ◽  
Cell Metabolism ◽  
Endothelial Cell Metabolism

Nutrition, endothelial cell metabolism, and atherosclerosis

1994 ◽  
Vol 34 (3) ◽  
pp. 253-282 ◽  
Author(s):  
Bernhard Hennig ◽  
Michal Toborek ◽  
Angelina Alvarado Cader ◽  
Eric A. Decker ◽  
Mary A. Stuart
Keyword(s):  
Endothelial Cell ◽  
Cell Metabolism ◽  
Endothelial Cell Metabolism

scholarly journals Endothelial cell metabolism

2017 ◽  
Vol 24 (3) ◽  
pp. 240-247 ◽  
Author(s):  
Laure-Anne Teuwen ◽  
Nihed Draoui ◽  
Charlotte Dubois ◽  
Peter Carmeliet
Keyword(s):  
Endothelial Cell ◽  
Cell Metabolism ◽  
Endothelial Cell Metabolism

Antiatherogenic properties of zinc: Implications in endothelial cell metabolism

Nutrition ◽  
1996 ◽  
Vol 12 (10) ◽  
pp. 711-717 ◽  
Author(s):  
Bernhard Hennig ◽  
Michal Toborek ◽  
Craig J. McClain
Keyword(s):  
Endothelial Cell ◽  
Cell Metabolism ◽  
Endothelial Cell Metabolism
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