Matrix metalloproteinase 1 1 G/2 G gene polymorphism is associated with acquired atrioventricular block via linking a higher serum protein level

Serum protein electrophoresis pattern can assist in diagnosis of liver disease, hematological disorders, renal disorders andgastrointestinal disease. Measurement of total protein level in the serum cannot detect any disorders in patient with normal limit ofserum total protein level. The aim of this study; was to evaluate the serum protein electrophoresis pattern in patient with normal limitsof serum protein level. This research was carried out by descriptive retrospective study using the electrophoresis data from patients’medical record at the Clinical Pathology Department, Dr. Hasan Sadikin General Hospital Bandung. The data of serum electrophoresis (bySebia gel electrophoresis) were grouped based on disease or disorders, and confirmed with the diagnosis derived from patient’s medicalrecord. Inclusion criteria of samples if ; the electrophoresis data were available, serum total protein level within normal limits (6.4–8.3mg/dL), and the data of electrophoresis taken from medical record were taken from August 2006 until August 2008. The result foundso far was, there were 240 data of electrophoresis from patients with serum protein level within normal limits (6.4–8.3 mg/dL). theinterpretation of electrophoresis consist of: 1) inflammation (149 patients; 62.2% ; sensitivity 83.7%, specificity 86,5%) 2) Cirrhosis(46 patients ; 19.2% ; sensitivity 87.5% ; specificity 88.4%) 3) Nephritic syndrome (15 patients ; 6.2%; sensitivity 53%; specificity96.9% 4) Monoclonal gammophaty (15 patients(6.2% ; sensitivity 80% ; specificity 98.7%) 5) Normal pattern in 15 patient (6.2%).This study found abnormal serum protein electrophoresis pattern in the condition of inflammation, Cirrhosis, Nephritic Syndrome, andMonoclonal gammophaty. It can be concluded that many disorders could be detected in patient with serum protein level within normallimits such as: inflammation, cirrhosis, nephritis syndrome and monoclonal gammophaty by abnormal electrophoresis pattern

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LEVELS AND PARTITION OF THE FOWL'S SERUM PROTEINS IN RELATION TO AGE AND EGG PRODUCTION

Canadian Journal of Biochemistry and Physiology ◽

10.1139/y55-110 ◽

1955 ◽

Vol 33 (1) ◽

pp. 891-903 ◽

Cited By ~ 17

Author(s):

W. E. Vanstone ◽

W. A. Maw ◽

R. H. Common

Keyword(s):

Serum Protein ◽

Protein Level ◽

Egg Production ◽

Serum Proteins ◽

Electrophoretic Pattern ◽

Total Serum Protein ◽

Total Serum ◽

Zone Electrophoresis ◽

Serum Protein Level ◽

New Protein

The level of total serum protein in the fowl has been followed from the 14th day of incubation to the 13th week of egg production. Serum proteins have been fractionated concurrently by zone electrophoresis in filter paper. Serum protein level in the 14-day embryo was 0.9 gm./100 ml. and the protein comprised a prealbumin fraction, albumin, α2- and β-globnlins. Sera from chicks aged seven days no longer contained a prealbumin fraction but α1-,α3- and γ-globulin fractions had appeared by this stage and the protein level had reached 2.3 gm./100 ml. Total serum protein in females increased to a maximum of about 5.4 gm./100 ml. in the week before laying of the first egg. By that time two new protein fractions had appeared. These new fractions accounted for the greater part of the increase over the levels (4.0 gm./100 ml.) prevailing in the prepuberal stage. Serum protein level declined during the first three weeks of laying to average levels below 4.0 gm./100 ml.; and this decline appeared to affect albumin and α1-globulin as well as the new fractions. As laying progressed, the total serum protein tended to regain a level around 4.0 gm./100 ml. The electrophoretic pattern also tended to return towards that prevailing in the week before laying. Some tentative correlations of the results of zone electrophoresis with published results for free electrophoresis of fowl serum proteins are presented.

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Relationship between Serum Protein Level and Body Composition in the Chick

Journal of Nutrition ◽

10.1093/jn/91.4.468 ◽

1967 ◽

Vol 91 (4) ◽

pp. 468-472 ◽

Cited By ~ 17

Author(s):

O. P. Thomas ◽

G. F. Combs

Keyword(s):

Body Composition ◽

Serum Protein ◽

Protein Level ◽

Serum Protein Level

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Blood Serum Protein Level as a Function of Age

Journal of Animal Science ◽

10.2527/jas1959.183983x ◽

1959 ◽

Vol 18 (3) ◽

pp. 983-990 ◽

Cited By ~ 12

Author(s):

B. L. Larson ◽

R. W. Touchberry

Keyword(s):

Blood Serum ◽

Serum Protein ◽

Protein Level ◽

Serum Protein Level ◽

Blood Serum Protein

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A COMPARATIVE STUDY BETWEEN PLEURAL FLUID CHOLESTEROLAND LIGHT'S CRITERIA FOR DIFFERENTIATION OF EXUDATIVE AND TRANSUDATIVE PLEURAL EFFUSION

10.36106/ijsr/8521988 ◽

2021 ◽

pp. 53-55

Author(s):

Narendranath Roy ◽

Apurba Bikash Pramanik ◽

Shampa Maity ◽

Pulakesh Sinha

Keyword(s):

Pleural Effusion ◽

Serum Protein ◽

Protein Level ◽

Urban Poor ◽

General Medicine ◽

Cost Effective ◽

Pleural Effusions ◽

Mechanism Of Formation ◽

Serum Protein Level ◽

Exudative Pleural Effusion

Introduction: Pleural effusion is one of the common clinical disorders encountered in the medical wards. In a patient with pleural effusion diagnosis can be arrived by history, clinical examination and radiological techniques. Pleural effusion is collection of uid in intrapleural space and manifestation of several diseases, both pulmonary and extra pulmonary, often isolated 1. Based on the underlying pathological abnormality and mechanism of formation, effusion may be either transudative or exudative. To nd out etiology, rst step is to differentiate whether the pleural effusion is of exudate or transudate type. Etiology of pleural effusions differ in different parts of the world. Aims And Objectives: The study is conducted to compare between pleural uid cholesterol and Light's criteria for differentiation of transudative and exudative pleural effusion. The sensitivity and specicity of pleural uid cholesterol estimation as an independent biochemical marker in exudative pleural effusion. Methodology: The present work was conducted in the N.R.S. Medical College and Hospital Kolkata(Department of GENERAL MEDICINE ). Study was done from February 2018 to 1st May 2019 i.e., through one year and three month period. 70 patients both male and female Patients admitted in N.R.S MEDICALCOLLEGE with symptoms suggestive of pleural effusion. Result And Analysis: Our study showed that mean serum protein level in tuberculous effusion patients is 6.322 gm/dl. In Para pneumonic effusion cases mean serum protein level is 6.867 gm/dl. Mean serum Protein level in transudative effusion cases is 6.923 gm/dl. In patients with malignant effusion, the mean serum protein level is 6.492 gm. /dl. In empyema patients, mean serum protein level is Summary: Pleural effusion develops in a variety of illnesses. Based on the underlying pathology and mechanism of formation, effusions may be either transudates or exudates. Analysis of pleural effusion is an important diagnostic step to guide further investigations and treatment. Conclusion: Pleural uid cholesterol with a cut-off value of >55 mg/dL is better than Light's criteria in the differentiation of exudative pleural effusions. The sensitivity and specicity of differentiation can be improved by combining pleural uid protein with pleural uid cholesterol. Both these criteria are cost effective than the Light's criteria because it does not require a simultaneous blood sampling for differentiation. So in a country like India where there is maximum nancial constraints, it will be helpful for rural and urban poor patients. In resource-limited settings, pleural uid cholesterol can replace Light's criteria for classication of pleural effusion

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