Death by SARS-CoV 2: a Romanian COVID-19 multi-centre comorbidity study

AbstractEvidence regarding the relation between SARS-CoV-2 mortality and the underlying medical condition is scarce. We conducted an observational, retrospective study based on Romanian official data about location, age, gender and comorbidities for COVID-19 fatalities. Our findings indicate that males, hypertension, diabetes, obesity and chronic kidney disease were most frequent in the COVID-19 fatalities, that the burden of disease was low, and that the prognosis for 1-year survival probability was high in the sample. Evidence shows that age-dependent pairs of comorbidities could be a negative prognosis factor for the severity of disease for the SARS-CoV 2 infection.

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Death by SARS-CoV 2 - a Romanian COVID-19 multi-centre comorbidity study

10.21203/rs.3.rs-38098/v2 ◽

2020 ◽

Author(s):

Anca Pantea Stoian ◽

Mihaela Pricop-Jeckstadt ◽

Adrian Pana ◽

Bogdan-Vasile Ileanu ◽

Ruxandra Schitea ◽

...

Keyword(s):

Chronic Kidney Disease ◽

Retrospective Study ◽

Kidney Disease ◽

Burden Of Disease ◽

Medical Condition ◽

Prognosis Factor ◽

Severity Of Disease ◽

Age Dependent ◽

Underlying Medical Condition ◽

Official Data

Abstract Evidence regarding the relation between SARS-CoV-2 mortality and the underlying medical condition is scarce. We conducted an observational, retrospective study based on Romanian official data about location, age, sex and comorbidities for COVID-19 fatalities. Our findings indicate that males, hypertension, diabetes, obesity and chronic kidney disease were most frequent in the COVID-19 fatalities, that the burden of disease was low, and that the prognosis for 1-year survival probability was high in the sample. Evidence shows that age-dependent pairs of comorbidities could be a negative prognosis factor for the severity of disease for the SARS-CoV 2 infection.

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Death by SARS-CoV 2 - a Romanian COVID-19 multi-centre comorbidity study

10.21203/rs.3.rs-38098/v1 ◽

2020 ◽

Cited By ~ 1

Author(s):

Anca Pantea Stoian ◽

Mihaela Pricop-Jeckstadt ◽

Adrian Pana ◽

Bogdan-Vasile Ileanu ◽

Ruxandra Schitea ◽

...

Keyword(s):

Chronic Kidney Disease ◽

Retrospective Study ◽

Kidney Disease ◽

Burden Of Disease ◽

Medical Condition ◽

Prognosis Factor ◽

Severity Of Disease ◽

Age Dependent ◽

Underlying Medical Condition ◽

Official Data

Abstract Evidence regarding the relation between SARS-CoV-2 mortality and the underlying medical condition is scarce. We conducted an observational, retrospective study based on Romanian official data about location, age, sex and comorbidities for COVID-19 fatalities. Our findings indicate that males, hypertension, diabetes, obesity and chronic kidney disease were most frequent in the COVID-19 fatalities, that the burden of disease was low, and that the prognosis for 1-year survival probability was high in the sample. Evidence shows that age-dependent pairs of comorbidities could be a negative prognosis factor for the severity of disease for the SARS-CoV 2 infection.

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The Psychosocial and Somatic Effects of Relocation from Remote Canadian First Nation Communities to Urban Centres on Indigenous Peoples with Chronic Kidney Disease (CKD)

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18073838 ◽

2021 ◽

Vol 18 (7) ◽

pp. 3838

Author(s):

Denise Genereux ◽

Lida Fan ◽

Keith Brownlee

Keyword(s):

Chronic Kidney Disease ◽

Kidney Disease ◽

Indigenous Peoples ◽

Health Care Professionals ◽

Medical Condition ◽

Geographical Location ◽

Well Being ◽

First Nation ◽

Urban Centre ◽

The Impact

Chronic kidney disease, also referred to as end-stage renal disease (ESRD), is a prevalent and chronic condition for which treatment is necessary as a means of survival once affected individuals reach the fifth and final stage of the disease. Dialysis is a form of maintenance treatment that aids with kidney functioning once a normal kidney is damaged. There are two main types of dialysis: hemodialysis (HD) and peritoneal dialysis (PD). Each form of treatment is discussed between the patient and nephrologist and is largely dependent upon the following factors: medical condition, ability to administer treatment, supports, geographical location, access to necessary equipment/supplies, personal wishes, etc. For Indigenous Peoples who reside on remote Canadian First Nation communities, relocation is often recommended due to geographical location and limited access to both health care professionals and necessary equipment/supplies (i.e., quality of water, access to electricity/plumbing, etc). Consequently, the objective of this paper is to determine the psychosocial and somatic effects for Indigenous Peoples with ESRD if they have to relocate from remote First Nation communities to an urban centre. A review of the literature suggests that relocation to urban centres has negative implications that are worth noting: cultural isolation, alienation from family and friends, somatic issues, psychosocial issues, loss of independence and role adjustment. As a result of relocation, it is evident that the impact is profound in terms of an individuals’ mental, emotional, physical and spiritual well-being. Ensuring that adequate social support and education are available to patients and families would aid in alleviating stressors associated with managing chronic kidney disease.

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Clinical outcomes among patients with chronic kidney disease hospitalized with diabetic foot disorders: A nationwide retrospective study

Endocrinology Diabetes & Metabolism ◽

10.1002/edm2.277 ◽

2021 ◽

Author(s):

Michael Salim

Keyword(s):

Chronic Kidney Disease ◽

Retrospective Study ◽

Kidney Disease ◽

Clinical Outcomes ◽

Diabetic Foot

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Increasing Body Mass Index Predicts Rapid Decline in Renal Function: A 5 Year Retrospective Study

Hormone and Metabolic Research ◽

10.1055/a-0599-6360 ◽

2018 ◽

Vol 50 (07) ◽

pp. 556-561 ◽

Cited By ~ 2

Author(s):

Xiaojing Ma ◽

Chengyin Zhang ◽

Hong Su ◽

Xiaojie Gong ◽

Xianglei Kong

Keyword(s):

Body Mass Index ◽

Chronic Kidney Disease ◽

Renal Function ◽

Retrospective Study ◽

Kidney Disease ◽

Body Mass ◽

Adult Population ◽

Rapid Decline ◽

Logistic Regression Models ◽

Baseline Bmi

AbstractWhile obesity is a recognized risk factor for chronic kidney disease, it remains unclear whether change in body mass index (ΔBMI ) is independently associated with decline in renal function (evaluated by the change in estimated glomerular filtration rate, ΔeGFR) over time. Accordingly, to help clarify this we conducted a retrospective study to measure the association of ΔBMI with decline in renal function in Chinese adult population. A total of 4007 adults (aged 45.3±13.7 years, 68.6% male) without chronic kidney disease at baseline were enrolled between 2008 and 2013. Logistic regression models were applied to explore the relationships between baseline BMI and ΔBMI, and rapid decline in renal function (defined as the lowest quartile of ΔeGFR ). During 5 years of follow-up, the ΔBMI and ΔeGFR were 0.47±1.6 (kg/m2) and –3.0±8.8 (ml/min/1.73 m2), respectively. After adjusted for potential confounders, ΔBMI (per 1 kg/m2 increase) was independently associated with the rapid decline in renal function [with a fully adjusted OR of 1.12 (95% CI, 1.05 to 1.20). By contrast, the baseline BMI was not associated with rapid decline in renal function [OR=1.05 (95% CI, 0.98 to 1.13)]. The results were robust among 2948 hypertension-free and diabetes-free participants, the adjusted ORs of ΔBMI and baseline BMI were 1.14 (95% CI, 1.05 to 1.23) and 1.0 (95% CI, 0.96 to 1.04) for rapid decline in renal function, respectively. The study revealed that increasing ΔBMI predicts rapid decline in renal function.

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