Effect of refractive error type in the amblyopic eyes on factors for treatment success in anisometropic amblyopia

AbstractTo investigate the factors for treatment success in anisometropic amblyopia according to the spherical equivalent (SE) type of amblyopic eyes. Medical records of 397 children with anisometropic amblyopia aged 3 to 12 years who presented in a secondary referral eye hospital during 2010 ~ 2016 were retrospectively reviewed. Anisometropia was defined as ≥ 1 diopter (D) difference in SE, or ≥ 1.5 D difference of cylindrical error between the eyes. According to the SE of amblyopic eyes, patients were categorized into hyperopia (SE ≥ 1D), emmetropia (− 1 < SE < + 1) and myopia (SE ≤ − 1D) groups. Treatment success was defined as achieving interocular logMAR visual acuity difference < 0.2. Multivariate logistic regression was used to analyze the factors for treatment success. Significant factors for the amblyopia treatment success in hyperopia group (n = 270) were younger age [adjusted odds ratio (aOR) (95% confidence interval, CI) = 0.529 (0.353, 0.792)], better BCVA in amblyopic eyes at presentation [aOR (95% CI) 0.004 (0, 0.096)], longer follow-up period [aOR (95%CI) = 1.098 (1.036, 1.162)], and no previous amblyopia treatment history [aOR (95% CI) 0.059 (0.010, 0.364)]. In myopia group (n = 68), younger age [aOR (95% CI) 0.440 (0.208, 0.928)] and better BCVA in amblyopic eyes [aOR (95% CI) 0.034 (0.003, 0.469)] were associated with higher odds of treatment success. There was no significant factor for treatment success in emmetropia group (n = 59) in this population. The refractive error type of amblyopic eyes at presentation affects the factors for treatment success in anisometropic amblyopia.

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Factors for Treatment Success in Anisometropic Amblyopia: Effect of Refractive Errors of the Amblyopic Eyes

10.21203/rs.3.rs-635271/v1 ◽

2021 ◽

Author(s):

Daye Diana Choi ◽

Dae Hee Kim ◽

Ungsoo Samuel Kim ◽

Seung-Hee Baek

Keyword(s):

Medical Records ◽

Odds Ratio ◽

Treatment Success ◽

Refractive Errors ◽

Spherical Equivalent ◽

Multivariate Logistic Regression ◽

Anisometropic Amblyopia ◽

Younger Age ◽

Significant Factors

Abstract Purpose: To investigate the factors for treatment success in anisometropic amblyopia according to the spherical equivalent (SE) type of amblyopic eyes. Methods: Medical records of 397 children with anisometropic amblyopia aged 3 to 12 years during 2010~2016 were retrospectively reviewed. Anisometropia was defined as ≥1 diopter (D) difference in SE, or ≥1.5 D difference of cylindrical error between the eyes. According to the SE of amblyopic eyes, patients were categorized into hyperopia (SE ≥1D), emmetropia (-1< SE <+1) and myopia (SE ≤-1D) groups. Treatment success was defined as achieving interocular LogMAR visual acuity difference < 0.2. Multivariate logistic regression was used to analyze the factors for treatment success.Results: Significant factors for the amblyopia treatment success in hyperopia group (n=270) were younger age [adjusted odds ratio (aOR) (95% confidence interval, CI) = 0.60 (0.41-0.88)], larger astigmatism of sound eye [aOR (95% CI) = 0.04 (0-0.78)], better BCVA in amblyopic eyes at presentation [aOR (95% CI) = 0.01 (0-0.16)], longer follow-up period [aOR (95%CI)=1.1 (1.04-1.17)], and no comorbid strabismus [aOR (95%CI)= 0.25 (0.06-0.99)]. In myopia group (n=68), older age [aOR (95% CI) =0.45 (0.20-0.97)] and worse BCVA in amblyopic eyes [aOR (95% CI) = 0.04 (0-0.61)] were inversely associated with higher odds of treatment success. There was no significant factor for treatment success in emmetropia group (n=59).Conclusions: The type of refractive error of amblyopic eyes at presentation affects the factors for treatment success of anisometropic amblyopia.

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Relationship between anosmia and hospitalisation in patients with coronavirus disease 2019: an otolaryngological perspective

The Journal of Laryngology & Otology ◽

10.1017/s0022215120001851 ◽

2020 ◽

Vol 134 (8) ◽

pp. 710-716 ◽

Cited By ~ 1

Author(s):

H Avcı ◽

B Karabulut ◽

A Farasoglu ◽

E Boldaz ◽

M Evman

Keyword(s):

Confidence Interval ◽

Patient Group ◽

Medical Records ◽

Odds Ratio ◽

Clinical Presentation ◽

Patient Treatment ◽

Younger Age ◽

Basic Characteristics ◽

The Relationship

AbstractObjectiveA study was carried out to evaluate the relationship between anosmia and hospital admission in coronavirus disease 2019 patients.MethodsThe clinical data of 1534 patients with confirmed coronavirus disease 2019 virus were analysed. The study was conducted with medical records of 1197 patients (78 per cent). The basic characteristics of patients and symptoms related to otolaryngology practice were examined. The patients were divided into two groups according to their follow up: an out-patient group and an in-patient group.ResultsThe majority of patients presented with anosmia (44.2 per cent), dysgeusia (43.9 per cent) and fever (38.7 per cent). Anosmia was observed in 462 patients (47 per cent) in the out-patient group, and in only 67 patients (31.2 per cent) in the in-patient group. Younger age (odds ratio = 1.05, 95 per cent confidence interval = 1.03–1.06) and the presence of anosmia (odds ratio = 2.04, 95 per cent confidence interval = 1.39–3) were significantly related to out-patient treatment.ConclusionAnosmia could be a symptom in the clinical presentation of the coronavirus disease 2019 infection.

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Risk factors for systemic thromboembolism after left chamber cardiac thrombi --- A retrospective multi-center study

10.21203/rs.2.14129/v1 ◽

2019 ◽

Author(s):

wei zhou ◽

Shun-yi Shi ◽

Yuan Ji ◽

Xin Chen ◽

Jun Huang ◽

...

Keyword(s):

Medical Records ◽

Heart Function ◽

Multivariate Logistic Regression ◽

Increased Risk ◽

All Cause Mortality ◽

History Of ◽

Multi Center Study ◽

Relationship Of ◽

The Relationship

Abstract Background : We aimed to characterize the independent predictors of systemic thromboembolism (ST) after left chamber thrombi. Methods: A retrospective analysis on the medical records of 175 patients diagnosed with left chamber thrombi by transthoracic echocardiography (TTE) at three centers were carried out. Multivariate logistic regression was performed to determine the relationship of each characteristic with ST. Multivariate Cox proportional survival analysis was conducted, with covariate adjustments, to identify predictors of all-cause mortality. Results: During a median 42 months of follow-up (25th–75th percentile: 20–62 months), 24 (13.7%) patients had ST, and 62 (35.4%) died. History of diabetes and thrombus mobility were independent predictors of ST (P = 0.003, P = 0.02, respectively). There was a significant association between abnormal ejection fraction (EF) and all-cause mortality (P = 0.003). Conclusions: The morbidity associated with ST and the increased risk for mortality associated with left chamber cardiac thrombi relates to medical history, thrombus state, and diminished heart function.

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Predictors of avascular necrosis in a cohort of Egyptian systemic lupus erythematosus patients: Retrospective two centers study

Current Rheumatology Reviews ◽

10.2174/1573397117666210907124242 ◽

2021 ◽

Vol 17 ◽

Author(s):

Abdelkawy A. Moghazy ◽

Amira M. Ibrahim

Keyword(s):

Avascular Necrosis ◽

Lupus Erythematosus ◽

Medical Records ◽

Disease Duration ◽

Univariate Analysis ◽

Multivariate Logistic Regression Analysis ◽

Multivariate Logistic Regression ◽

University Hospitals

Background: Avascular necrosis is a common complication in patients with SLE. Objective: This study aimed to investigate the risk factors for occurrence of avascular necrosis among SLE patients receiving steroid therapy at various doses, in combination with immunosuppressants. Methods: In this retrospective study, the medical records of all SLE patients under follow-up at the outpatient clinics of Cairo and kafr Elsheikh University hospitals through the period from November 2014 to August 2019, were included. The avascular necrosis was diagnosed by the findings of different imaging modalities. Results: We retrieved the medical records of 770 SLE patients during the study period; of them, 55 patients (7.1%) had avascular necrosis. There was significant higher usage of cyclophosphamide (p = 0.003), total cumulative dose of steroids 15-35g plus immunosuppressants (p < 0.001), and steroids >35g plus Immunosuppressants (p = 0.016) in avascular necrosis cohort. Based on the univariate analysis, disease duration more than five years and cumulative use of steroids were statistically significant predictors for the evolvement of avascular necrosis. Multivariate logistic regression analysis revealed that disease duration more than five years was associated independently with avascular necrosis. Conclusion: Our data seem to show a role of the association of immunosuppressant plus steroid on the risk to develop avascular necrosis.

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Identification of risk factors for recurrent febrile convulsion

Paediatrica Indonesiana ◽

10.14238/pi49.2.2009.87-9 ◽

2009 ◽

Vol 49 (2) ◽

pp. 87

Author(s):

Nadirah Rasyid Ridha ◽

P. Nara ◽

Hadia Angriani ◽

Dasril Daud

Keyword(s):

Family History ◽

Medical Records ◽

Febrile Convulsion ◽

Controlled Study ◽

Multivariate Logistic Regression ◽

Younger Age ◽

Increased Risk ◽

The Family ◽

History Of ◽

Lower Temperature

Background Febrile convulsion (FC) occurs in about 2 to 4percent of all children, approximately one third of whom willthen develop recurrent febrile convulsion (RFC). Risk factorsfor RFC are family history of convulsions, an age of less than 18months, a relatively lower temperature and shorter duration offever preceeding the first FC.Objective The aim of the study was to determine the risk factorsfor RFC.Methods One hundred children aged 6 months to 5 years withFC or RFC were included in this case-controlled study, which wascarried out from July 2006 to June 2007. Data on the children'sfirst FC were collected from medical records and the family historywas taken directly from the parents.Results Fifty children with RFC and 50 children withoutrecurrence were included in this study. An age of less than 18months (P< 0.0001, COR= 71.37), a family history of FC(P< 0.0001, COR= 6.00), and a fever duration ofless than 12hours preceding the first FC (P< 0.0001, COR = 4.96) wereassociated with a risk of recurrence. A relatively lower degree oftemperature at first febrile convulsion did not increase the riskfor RFC (P = 1.21). Multivariate logistic regression showed thatyounger age and shorter duration of fever preceding the first FCwere associated with RFC.Conclusion Younger age and shorter duration of fever precedingthe first FC are associated with an increased risk ofRFC.

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Factors Associated With Fast Recovery of Bell Palsy in Children

Journal of Child Neurology ◽

10.1177/0883073819877098 ◽

2019 ◽

Vol 35 (1) ◽

pp. 71-76 ◽

Cited By ~ 2

Author(s):

Yeseul Lee ◽

Hoi SooYoon ◽

Seung Geun Yeo ◽

Eun Hye Lee

Keyword(s):

Medical Records ◽

Recovery Rate ◽

Complete Recovery ◽

Fast Recovery ◽

Factors Affecting ◽

Younger Age ◽

Late Treatment ◽

Recovery Group ◽

Bell Palsy

The purpose of this study was to identify the clinical characteristics and factors affecting the prognosis of children with Bell palsy. We retrospectively reviewed the medical records of 53 pediatric patients diagnosed with Bell palsy. After a mean follow-up period of 30 days, 30 patients (56%) were completely recovered, 21 patients (40%) were partially recovered, and 2 patients (4%) had not recovered. The patients in the complete recovery group were significantly younger than those in the partial and nonrecovery groups (8.8 ± 4.2 years vs 12.2 ± 3.0 years, P = .003). Patients <8 years old had a higher complete recovery rate than was found in patients >8 years old (80% vs 47%, P = .031). Sex, affected side, and early or late treatment did not influence the recovery rate. These results suggest that younger age may be a good prognostic factor affecting the fast recovery of children with Bell palsy.

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Safety, Efficacy, and Predictive Factors of Conventional Epithelium-Off Corneal Crosslinking in the Treatment of Progressive Keratoconus

Journal of Ophthalmology ◽

10.1155/2020/7487186 ◽

2020 ◽

Vol 2020 ◽

pp. 1-7

Author(s):

Rebecca Farhat ◽

Mohamad Khaled Ghannam ◽

Georges Azar ◽

Joseph Nehme ◽

Marwan Sahyoun ◽

...

Keyword(s):

Predictive Factors ◽

Treatment Success ◽

Corneal Transplantation ◽

Primary Treatment ◽

Corneal Crosslinking ◽

Younger Age ◽

Corrected Distance Visual Acuity ◽

Clinical Benefits ◽

The Mean

Purpose. To report predictive factors of outcome of conventional epithelium-off corneal crosslinking (CXL) in the treatment of progressive keratoconus. Methods. This is a monocentric observational retrospective study conducted at Eye and Ear International Hospital, Lebanon. All patients with progressive keratoconus who underwent CXL between January 2008 and January 2016, with minimal 3-years follow-up were included. Primary treatment outcomes were maximum keratometry (K max), best-corrected distance visual acuity (CDVA), and failure. Failure was defined as an increase of 1.00 diopters (D) or more in K max and/or an increase of 0.1 logMAR or more in CDVA and conversion to corneal transplantation. Statistical analysis was done to identify predictors of treatment success. Univariate and multivariate analyses were performed to determine the correlations between baseline parameters and outcomes, and an equation for predicting K max and CDVA was created. Results. 156 eyes of 102 patients were enrolled. The mean age was 23.85 ± 6.52 years. Failure occurred in 31 eyes (19.87%). Gender and thinnest pachymetry did not have any impact on postoperative outcomes. Concerning the CDVA outcome, multivariate analysis showed that a better preoperative CDVA was associated with higher improvement in CDVA, and higher baseline K max and higher posterior mean K were associated with a worse outcome CDVA. Regarding postoperative K max, a higher baseline K max, a worse baseline CDVA, and a younger age were associated with less flattening postoperatively. Conclusion. CXL is a safe and effective method in treating progressive keratoconus. However, the clinical benefits can differ among patients, and in our series, a nonnegligible number of cases show a continued progression of their ectasia. Further studies to identify predictors of postoperative progression prior to the procedure could help sort out good responders to treatment.

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The affected factors of loss to follow up (LFU) among HIV patients with antiretroviral therapy (ART) in Dr. Sardjito General Hospital, Yogyakarta, Indonesia

Indonesian Journal of Pharmacology and Therapy ◽

10.22146/ijpther.481 ◽

2020 ◽

Vol 1 (1) ◽

Author(s):

Sri Purwaningsih ◽

Yanri Wijayanti Subronto ◽

Erna Kristin

Keyword(s):

Antiretroviral Therapy ◽

Functional Status ◽

General Hospital ◽

Medical Records ◽

Hiv Patients ◽

Early Therapy ◽

Loss To Follow Up ◽

Medical Status ◽

Significant Factors

HIV infection is a global issue which is related to the increasing cases of HIV and AIDS in various countries including in Indonesia. Antiretroviral therapy (ART) that addressed for reducing the virus proliferation is not always followed by good medication adherence among patients. The ART loss to follow up (LFU) is a common problem in Indonesia. However, information concerning the affected factors of LFU among HIV patients with ART is limited. This study aimed to investigate the affected factors of LFU among HIV patients in the early two years of ART. A retrospective cohort study was conducted in Dr. Sardjito General Hospital, Yogyakarta among 369 medical records of HIV patients that met the inclusion and exclusion criteria. The inclusion criteria were HIV patients who started ART in January 2008 to December 2012, aged > 17 years with a complete medical records. The data of sociodemography and medical status patients were obtained from medical record, ART, and pharmacy register of the patients. Patient characteristics observed in this study included demographic factors such as age, sex, residence, education level, risk factors, and also medical status factors such as clinical stage, tuberculosis (TB) co-infection, functional status, and CD4 cell counts. The data were analyzed using Kaplan Meier and Cox Proportional Hazard. The results showed that patients with TB co-infection in early therapy and working functional status were significant factors of LFU (p<0.05). Patients without TB co-infection were half as much protected from LFU compared to patients with TB infection (HR=0.50; 96%CI: 0.34-0.75). It can be concluded that TB coinfection in early therapy and working fuctional status are the significant factors that influenced the LFU incidents in the two years of early therapy.

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The Link Between Verbal Short-Term Memory and Anomia Treatment Gains

American Journal of Speech-Language Pathology ◽

10.1044/2019_ajslp-18-0176 ◽

2019 ◽

Vol 28 (3) ◽

pp. 1039-1052

Author(s):

Reva M. Zimmerman ◽

JoAnn P. Silkes ◽

Diane L. Kendall ◽

Irene Minkina

Keyword(s):

Short Term Memory ◽

Controlled Trial ◽

Treatment Success ◽

Linear Regression Models ◽

Language Performance ◽

Short Term ◽

Term Memory ◽

Treatment Gains ◽

Post Hoc

Purpose A significant relationship between verbal short-term memory (STM) and language performance in people with aphasia has been found across studies. However, very few studies have examined the predictive value of verbal STM in treatment outcomes. This study aims to determine if verbal STM can be used as a predictor of treatment success. Method Retrospective data from 25 people with aphasia in a larger randomized controlled trial of phonomotor treatment were analyzed. Digit and word spans from immediately pretreatment were run in multiple linear regression models to determine whether they predict magnitude of change from pre- to posttreatment and follow-up naming accuracy. Pretreatment, immediately posttreatment, and 3 months posttreatment digit and word span scores were compared to determine if they changed following a novel treatment approach. Results Verbal STM, as measured by digit and word spans, did not predict magnitude of change in naming accuracy from pre- to posttreatment nor from pretreatment to 3 months posttreatment. Furthermore, digit and word spans did not change from pre- to posttreatment or from pretreatment to 3 months posttreatment in the overall analysis. A post hoc analysis revealed that only the less impaired group showed significant changes in word span scores from pretreatment to 3 months posttreatment. Discussion The results suggest that digit and word spans do not predict treatment gains. In a less severe subsample of participants, digit and word span scores can change following phonomotor treatment; however, the overall results suggest that span scores may not change significantly. The implications of these findings are discussed within the broader purview of theoretical and empirical associations between aphasic language and verbal STM processing.

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J 5 — A Data Processing System for Medical Information

Methods of Information in Medicine ◽

10.1055/s-0038-1636653 ◽

1967 ◽

Vol 06 (01) ◽

pp. 1-6

Author(s):

P. Hall ◽

Ch. Mellner ◽

T. Danielsson

Keyword(s):

Medical Records ◽

Medical Information ◽

Health Care Systems ◽

Processing System ◽

Linear Pattern ◽

Flexible Form ◽

Care Systems ◽

Pattern Recognition Analysis ◽

Numeric Information

A system for medical information has been developed. The system is a general and flexible one which without reprogramming or new programs can accept any alphabetic and/or numeric information. Coded concepts and natural language can be read, stored, decoded and written out. Medical records or parts of records (diagnosis, operations, therapy, laboratory tests, symptoms etc.) can be retrieved and selected. The system can process simple statistics but even make linear pattern recognition analysis.The system described has been used for in-patients, outpatients and individuals in health examinations.The use of computers in hospitals, health examinations or health care systems is a problem of storing information in a general and flexible form. This problem has been solved, and now it is possible to add new routines like booking and follow-up-systems.

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