scholarly journals Psychological symptoms and salivary inflammatory biomarkers in patients with dentofacial deformities: a case–control study

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Maria C. C. Volkweis ◽  
Gabriela W. Neculqueo ◽  
Raquel D. S. Freitas ◽  
Ana P. A. Dagnino ◽  
Guilherme G. Fritscher ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Case Control Study ◽  
Psychological Symptoms ◽  
Case Control ◽  
Inflammatory Biomarkers ◽  
World Health ◽  
Satisfaction With Life Scale ◽  
Dentofacial Deformities ◽  
Control Study

AbstractIndividuals with dentofacial deformities often display a low quality of life (QoL) through biological mechanisms that remain unraveled. In this case–control study, the salivary levels of cytokines, glutamate, and kynurenine metabolites were assessed in patients undergoing orthognathic surgery (OS), while correlating these parameters with QoL and psychological symptoms. Thirty-six patients were enrolled in control (under orthodontic treatment) and test (undergoing OS) groups, matched by age and sex. The QoL was assessed through the World Health Organization Quality of Life BREF (WHOQOL-BREF) and the Orthognathic Quality of Life Questionnaire (OQLQ). The psychological symptoms were evaluated by the Satisfaction with Life Scale, the Rosenberg Self-Esteem Scale (RSES), and the Depression, Anxiety, and Stress Scale-21 (DASS-21). The salivary levels of IL-1β, IL-6, IL-10, glutamate, and kynurenine metabolites were evaluated. The OQLQ demonstrated increased QoL scores in the test group, regarding social aspects, facial esthetics, and function domains, without significant differences in respect to the other surveys. These patients displayed higher IL-1β and glutamate levels; conversely, the kynurenine metabolites were unaltered. The glutamate levels positively correlated with the OQLQ function scores. The data brings novel evidence about the psychobiological features of patients with dentofacial deformities, showing salivary variations of inflammatory biomarkers in these individuals.

scholarly journals Quality of Life and Anxious-depressive Symptoms in Cancer Patients Undergoing Mindfulness-based Interventions: Feasibility and Preliminary Outcomes on Prospective Single-centre Case-control Study (MIND4ME St.)

2017 ◽  
Vol 41 (S1) ◽  
pp. S252-S252
Author(s):  
G. Pontoni ◽  
M. Maur ◽  
R. Ferrari ◽  
A. Guida ◽  
S. Poletti ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Depressive Symptoms ◽  
Cancer Patients ◽  
Case Control Study ◽  
Psychological Symptoms ◽  
Daily Practice ◽  
Case Control ◽  
Depression And Anxiety ◽  
Control Study

BackgroundMindfulness based interventions (MBIs) have shown efficacy in improving psychological symptoms including depression and anxiety in cancer patients (pts). The study aimed to explore feasibility and reproducibility of MBIs in an Italian Cancer Centre measuring biochemical and psychological parameters.MethodsIn this pilot prospective case-control study, we recruited newly diagnosed pts receiving adjuvant chemotherapy (CT). A MBIs program was designed consisting of 2.5 hours weekly for 8 weeks and, including meditation, yoga and body scan. Material for 45 minutes (mn) home daily practice was provided. Primary endpoint was to evaluate feasibility. Secondary endpoints were assessment of quality of life (QoL), psychological and biochemical outcomes of stress, tested at baseline (W0), W4, W8, W24, W48. PSS (Perceived Stress Reduction), POMS (profile of mood states scores), EuroQoL (EQ-5D-3L) were administered.ResultsTen pts underwent MBIs program arm. We present preliminary results, while data of control arm are being collected. All pts were female, two pts (20%) dropped out. Median age was 56 years. All received adjuvant CT, 5/8 received radiotherapy and hormone therapy. Mean of sessions attending was 6.8 (76%). Median daily practice was 30 mn. EQ-5D item for depression and anxiety showed decreasing trend in mean score from moderate to light (P = 0.15) and significant improvement of auto-perceived QoL was observed comparing W0 and W8 (P = 0.02)ConclusionsIn a sensitive setting such as start CT, we found high pts compliance to MBIs. Improvement in self-perceived QoL after starting program was found and comparing anxious-depressive symptoms outcomes with control arm is still needed.Disclosure of interestThe authors have not supplied their declaration of competing interest.

scholarly journals Impact of Recurrent Urinary Infections on the Quality of Life of Women in Outpatient Care: a Case-control Study

2021 ◽  
Author(s):  
Luciano Garcia Lourenção ◽  
Jacqueline Flores de Oliveira ◽  
José Carlos Carraro Eduardo ◽  
Giovani Machado Homem ◽  
Carlos Augusto Faria
Keyword(s):  
Quality Of Life ◽  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Case Control Study ◽  
Case Control ◽  
World Health ◽  
Recurrent Urinary Tract Infections ◽  
Tract Infections ◽  
Control Study

Abstract Background: The repetitive urinary tract infections impact women's quality of life and represent an important problem for women's physical and mental health, causing relevant social impacts. This study aimed to evaluate the impact of recurrent urinary tract infections on the quality of life of women with recurrent infections.Methods: This is a case-control study with 49 women with recurrent urinary tract infections, confirmed by urine culture, without complications and 49 women without recurrent urinary tract infections, seen at an outpatient clinic of a public teaching hospital in the city of Niterói, Rio de Janeiro, Brazil. Quality of life was evaluated using the Brazilian version of the World Health Organization's shortened questionnaire, the WHOQOL-Bref.Results: Women with urinary tract infections showed greater impairment of quality of life in the physical (p = 0.007) and psychological (p = 0.038) domains, with lower quality of life score in their self-assessment (p = 0.002), when compared to the group control. Women with recurrent urinary infection had mean scores significantly lower than the control group in the Energy and fatigue (p = 0.003), Positive feelings (p = 0.014), Self-esteem (p = 0.040), Dependence on medication (p = 0.029), Negative feelings (p = 0.023) and Recreation and leisure (p = 0, 0.041).Conclusions: Recurrent urinary tract infections have an important impact on the quality of life of women, especially in the Physical and Psychological domains, representing a significant problem for women, health professionals, and the health system.

Quality of life in type 2 diabetics with gastroesophageal reflux disease: a case control study

2013 ◽  
Vol 45 (4) ◽  
pp. 194-199 ◽  
Author(s):  
R. Promberger ◽  
A. Spitzer ◽  
J. Ott ◽  
J. Lenglinger ◽  
W. Eilenberg ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Reflux Disease ◽  
Case Control Study ◽  
Case Control ◽  
Type 2 Diabetics ◽  
Control Study

Quality of Life and Physical Activity in Liver Transplantation Patients: Results of a Case-Control Study in Italy

2012 ◽  
Vol 44 (5) ◽  
pp. 1346-1350 ◽  
Author(s):  
D. Masala ◽  
A. Mannocci ◽  
B. Unim ◽  
A. Del Cimmuto ◽  
F. Turchetta ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Physical Activity ◽  
Liver Transplantation ◽  
Case Control Study ◽  
Case Control ◽  
Control Study

scholarly journals Quality of life in alopecia areata: A case-control study

2014 ◽  
Vol 6 (1) ◽  
pp. 8 ◽  
Author(s):  
TacianaRocha de Hollanda ◽  
Marcia Ramos-e-Silva ◽  
CelsoTavares Sodre ◽  
MarcoAntonio Brasil
Keyword(s):  
Quality Of Life ◽  
Alopecia Areata ◽  
Case Control Study ◽  
Case Control ◽  
Control Study

scholarly journals Risk factors associated with peripheral neuropathy among diabetic individuals: a case control study

2021 ◽  
Vol 8 (2) ◽  
pp. 768
Author(s):  
Christa Kingston ◽  
Aravindan J. ◽  
Srikumar Walsalam
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Diabetic Neuropathy ◽  
Case Control Study ◽  
Case Control ◽  
Diabetic Patients ◽  
Factors Associated ◽  
History Of ◽  
Control Study

Background: Diabetic neuropathy is one among the most common complication in diabetes mellitus. Diabetic peripheral neuropathy hinders the quality of life causing morbidity and mortality. The purpose of this study was to find the risk factors associated with diabetic neuropathy.Methods: This case control study involved 100 diabetic patients attending the Dohnavur fellowship hospital, Dohnavur from October 2019 to March 2020. Sociodemographic profile and diabetic characteristics of the study group were obtained and analysed. Diagnosis of Diabetic Neuropathy was done by using the diagnostic method proposed by American Diabetic Association.Results: Of the total study population with mean age 59.43 years, 63% had family history of diabetes. Almost 70% had poor diabetic control. Statistically significant relationships were found between neuropathy and duration of diabetes, glycaemic control, history of hypertension, monofilament test and pinprick sensation.Conclusions: In this study, glycemic control, dyslipidemia and hypertension were modifiable risk factors for diabetic neuropathy. Early interventional programs to sensitize diabetics on these factors could improve the quality of life of Diabetic patients. 

Sign in / Sign up

Export Citation Format

Share Document