scholarly journals Outcome of patients with HIV-related germ cell tumours: a case–control study

2004 ◽  
Vol 90 (8) ◽  
pp. 1526-1530 ◽  
Author(s):  
T Powles ◽  
M Bower ◽  
J Shamash ◽  
J Stebbing ◽  
J Ong ◽  
...  
Keyword(s):  
Germ Cell ◽  
Case Control Study ◽  
Case Control ◽  
Germ Cell Tumours ◽  
Control Study

The Inter-Regional, Epidemiological Study of Childhood Cancer (IRESCC): case-control study in children with germ cell tumours

1986 ◽  
Vol 7 (5) ◽  
pp. 717-722 ◽  
Author(s):  
H.E. Johnston ◽  
J.R. Mann ◽  
J. Williams ◽  
J.A.H. Waterhouse ◽  
J.M. Birch ◽  
...  
Keyword(s):  
Germ Cell ◽  
Childhood Cancer ◽  
Epidemiological Study ◽  
Case Control Study ◽  
Case Control ◽  
Germ Cell Tumours ◽  
Control Study

scholarly journals Parental occupational exposures in wood-related jobs and risk of testicular germ cell tumours in offspring in NORD-TEST a registry-based case–control study in Finland, Norway, and Sweden

2021 ◽  
Author(s):  
Sara Corbin ◽  
Kayo Togawa ◽  
Joachim Schüz ◽  
Charlotte Le Cornet ◽  
Beatrice Fervers ◽  
...  
Keyword(s):  
Germ Cell ◽  
Case Control Study ◽  
Occupational Exposures ◽  
Case Control ◽  
Germ Cell Tumours ◽  
Prenatal Exposures ◽  
Testicular Germ Cell ◽  
Testicular Germ Cell Tumours ◽  
Increased Risk ◽  
Control Study

Abstract Objective We assessed the association between parental prenatal exposures in wood-related jobs and risk of testicular germ cell tumours (TGCT) in offspring. Methods NORD-TEST, a registry-based case–control study in Sweden, Finland and Norway, included 8112 TGCT cases diagnosed at ages 14–49 years between 1978 and 2012 with no history of prior cancer, and up to four controls matched to each case on year and country of birth. Parents of cases and controls were identified via linkages with the population registries and their occupational information was retrieved from censuses. The Nordic Occupational Cancer Study Job-Exposure Matrix was used to assign occupational exposures to each parent. Logistic regression models were used to estimate odds ratios (OR) and 95% confidence intervals (CI). Results Maternal wood-related job was not associated with the risk of TGCT in offspring (OR 1.08, CI 0.55–2.14), while paternal wood-related job was associated with a decreased risk of TGCT in offspring (OR 0.85, CI 0.75–0.96). None of the specific wood-related jobs, such as upholsterers, sawyers, or construction carpenters, were significantly associated with a risk of TGCT. Only exception was observed in a sensitivity analysis which showed an increased risk in the small group of sons of fathers working as ‘cabinetmakers and joiners’ the year before conception (OR of 2.06, CI 1.00–4.25). Conclusion This large-scale NORD-TEST analysis provided no evidence of an association between parental prenatal exposures in wood-related jobs and TGCT in sons.

scholarly journals A population-based case–control study on social factors and risk of testicular germ cell tumours

BMJ Open ◽  
2013 ◽  
Vol 3 (9) ◽  
pp. e003833 ◽  
Author(s):  
Nils Schmeisser ◽  
David I Conway ◽  
Andreas Stang ◽  
Ingeborg Jahn ◽  
Christa Stegmaier ◽  
...  
Keyword(s):  
Germ Cell ◽  
Social Factors ◽  
Case Control Study ◽  
Population Based ◽  
Case Control ◽  
Germ Cell Tumours ◽  
Testicular Germ Cell ◽  
Testicular Germ Cell Tumours ◽  
Control Study

Molecular markers in extragonadal germ cell tumours: a matched case?control study

2007 ◽  
Vol 50 (3) ◽  
pp. 394-396
Author(s):  
D Pectasides ◽  
C Valavanis ◽  
M Nikolaou ◽  
G Aravantinos ◽  
I Lekka ◽  
...  
Keyword(s):  
Molecular Markers ◽  
Germ Cell ◽  
Case Control Study ◽  
Case Control ◽  
Germ Cell Tumours ◽  
Matched Case ◽  
Matched Case Control Study ◽  
Control Study

scholarly journals Parental occupation and childhood germ cell tumors: a case–control study in Denmark, 1968–2016

2021 ◽  
Author(s):  
Clinton Hall ◽  
Johnni Hansen ◽  
Jørn Olsen ◽  
Di He ◽  
Ondine S. von Ehrenstein ◽  
...  
Keyword(s):  
Germ Cell ◽  
Maternal Employment ◽  
Case Control Study ◽  
Germ Cell Tumors ◽  
Social Contact ◽  
Case Control ◽  
Yolk Sac ◽  
Parental Occupation ◽  
Yolk Sac Tumors ◽  
Control Study

Abstract Purpose To examine associations between parental occupation and childhood germ cell tumors (GCTs) in offspring while distinguishing by common histologic subtype (i.e., yolk sac tumor and teratoma). Methods This population-based case–control study included childhood GCT cases in Denmark diagnosed 1968–2015 (< 16 years old at diagnosis) and sex and birth year-matched controls. Demographic information and parental employment histories were obtained from Danish registries. Parental occupation was assessed by industry; job-exposure matrices were used to examine specific occupational exposures (i.e., potentially carcinogenic organic solvents and social contact). Conditional multivariable logistic regression models were used to estimate odds ratios (OR) and 95% confidence intervals (CIs). Results Overall, 178 childhood GCT cases (50 yolk sac tumors; 65 teratomas) and 4,355 controls were included for analysis. Maternal employment in education during pregnancy was associated with offspring GCTs (OR 2.45, 95% CI 1.23–4.90), especially yolk sac tumors (OR 5.27, 95% CI 1.94–14.28). High levels of both maternal and paternal occupational social contact were also associated with offspring yolk sac tumors across all exposure periods (ORs 2.30–4.63). No signals were observed for paternal occupational solvent exposure, while imprecise associations were estimated for maternal exposure (e.g., dichloromethane exposure during pregnancy, OR 1.51, 95% CI 0.77–2.95). Conclusion Our findings suggest that parental occupation is associated with offspring GCTs, with most consistent evidence supporting an association between maternal employment in education or other high social contact jobs and offspring yolk sac tumors.

Case-control study of male germ cell tumors nested in a cohort of car-manufacturing workers: Findings from the occupational history

2010 ◽  
Vol 53 (10) ◽  
pp. 1006-1018 ◽  
Author(s):  
Ingo Langner ◽  
Nils Schmeißer ◽  
Birte Mester ◽  
Thomas Behrens ◽  
Andrea Gottlieb ◽  
...  
Keyword(s):  
Germ Cell ◽  
Case Control Study ◽  
Germ Cell Tumors ◽  
Case Control ◽  
Male Germ Cell ◽  
Occupational History ◽  
Control Study

Molecular markers in extragonadal germ cell tumors (EGCTs): A matched-case control study

2005 ◽  
Vol 23 (16_suppl) ◽  
pp. 9700-9700
Author(s):  
M. Nikolaou ◽  
C. Valavanis ◽  
I. Lekka ◽  
G. Aravantinos ◽  
G. Fountzilas ◽  
...  
Keyword(s):  
Molecular Markers ◽  
Germ Cell ◽  
Case Control Study ◽  
Germ Cell Tumors ◽  
Case Control ◽  
Matched Case ◽  
Matched Case Control Study ◽  
Extragonadal Germ Cell Tumors ◽  
Control Study

scholarly journals Advancing Parental Age and Risk of Solid Tumors in Children: A Case-Control Study in Peru

2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Ligia Rios ◽  
Liliana Vásquez ◽  
Mónica Oscanoa ◽  
Iván Maza ◽  
Jenny Gerónimo
Keyword(s):  
Germ Cell ◽  
Childhood Cancer ◽  
Solid Tumors ◽  
Case Control Study ◽  
Germ Cell Tumors ◽  
Case Control ◽  
Paternal Age ◽  
Parental Age ◽  
Advanced Paternal Age ◽  
Control Study

Background. The causes of childhood cancer are not well known, but the advanced age of the parents has been suggested as a risk factor for childhood cancer in several observational studies. In this study, we examine a possible link between parental age and childhood solid tumors. Methods. We conducted a hospital-based case-control study (310 cases and 620 controls, matched by age and gender) at Rebagliati Hospital, Lima, Peru. Odd ratio was used to compare categories of advancing maternal and paternal age with and without adjusting for possible confounding factors were calculated. Results. The risk of childhood retinoblastoma was significantly higher among children of mothers aged> 35 years (adjusted OR 1.21; 95% CI, 1.09-6.08) and fathers aged> 35 years (OR 1.17; 1.01-16.33). A significant trend with increasing mother's age (p = 0.037) and father's age (p = 0.005) was found. There were more risks to development of non-Hodgkin's lymphoma (p = 0.047) and gonadal germ cell tumors (p = 0.04) for advanced paternal age. There was a strong protective effect of increasing parity on risk of solid tumors in children (p=0.0015). Conclusion. Our results suggest that advanced parental age is associated with the risk for the development of retinoblastoma. Advanced paternal age increases the risk of non-Hodgkin lymphoma and gonadal germ cell tumor. The higher the order of birth of the children, the less the chance of developing any neoplasm.

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