scholarly journals Measuring cell surface area and deformability of individual human red blood cells over blood storage using quantitative phase imaging

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
HyunJoo Park ◽  
SangYun Lee ◽  
Misuk Ji ◽  
Kyoohyun Kim ◽  
YongHak Son ◽  
...  
2016 ◽  
Vol 55 (10) ◽  
pp. 2521 ◽  
Author(s):  
Vishesh Dubey ◽  
Gyanendra Singh ◽  
Veena Singh ◽  
Azeem Ahmad ◽  
Dalip Singh Mehta

2016 ◽  
Author(s):  
Joonseok Hur ◽  
Kyoohyun Kim ◽  
SangYun Lee ◽  
HyunJoo Park ◽  
YongKeun Park

Here, the actions of melittin, the active molecule of apitoxin or bee venom, were investigated on human red blood cells (RBCs) using quantitative phase imaging techniques. High-resolution realtime 3-D refractive index (RI) measurements and dynamic 2-D phase images of individual melittin-bound RBCs enabled in-depth examination of melittin-induced biophysical alterations of the cells. From the measurements, morphological, biochemical, and mechanical alterations of the RBCs were analyzed quantitatively. Furthermore, leakage of haemoglobin (Hb) inside the RBCs at high melittin concentration was also investigated.


Author(s):  
M. Zolotova ◽  
M. Ivashchenko ◽  
P. Ignatiev ◽  
V. Metelin ◽  
M. Talamanova

The possibility of quantitative phase imaging method for the assessment of structural morphological erythrocytes peculiarities under normal and stress conditions were studied. It is stated that quantitative phase imaging is an important instrument which allows to visualize red blood cells. New aspects of stress influence on functional cells morphology are defined.


2016 ◽  
Vol 21 (9) ◽  
pp. 090505 ◽  
Author(s):  
Paula M. S. Roma ◽  
Livia Siman ◽  
Barbara Hissa ◽  
Ubirajara Agero ◽  
Erika M. Braga ◽  
...  

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