Carbon dots for copper detection with down and upconversion fluorescent properties as excitation sources

It is important to understand the nanomaterials intracellular trafficking and distribution and investigate their targeting into the nuclear area in the living cells. In our previous study, we firstly observed penetration of nonmodified positively charged carbon dots decorated with quaternary ammonium groups (QCDs) into the nucleus of mouse NIH/3T3 fibroblasts. Thus, in this work, we focused on deeper study of QCDs distribution inside two healthy mouse NIH/3T3 and L929 cell lines by fluorescence microspectroscopy and performed a comprehensive cytotoxic and DNA damage measurements. Real-time penetration of QCDs across the plasma cell membrane was recorded, concentration dependent uptake was determined and endocytic pathways were characterized. We found out that the QCDs concentration of 200 µg/mL is close to saturation and subsequently, NIH/3T3 had a different cell cycle profile, however, no significant changes in viability (not even in the case with QCDs in the nuclei) and DNA damage. In the case of L929, the presence of QCDs in the nucleus evoked a cellular death. Intranuclear environment of NIH/3T3 cells affected fluorescent properties of QCDs and evoked fluorescence blue shifts. Studying the intracellular interactions with CDs is essential for development of future applications such as DNA sensing, because CDs as DNA probes have not yet been developed.

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Human fingernails as an intriguing precursor for the synthesis of nitrogen and sulfur-doped carbon dots with strong fluorescent properties: Analytical and bioimaging applications

Sensors and Actuators B Chemical ◽

10.1016/j.snb.2018.04.059 ◽

2018 ◽

Vol 267 ◽

pp. 494-501 ◽

Cited By ~ 25

Author(s):

Theodoros Chatzimitakos ◽

Athanasia Kasouni ◽

Lamprini Sygellou ◽

Ioannis Leonardos ◽

Anastasios Troganis ◽

...

Keyword(s):

Carbon Dots ◽

Fluorescent Properties ◽

Doped Carbon Dots

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Chitosan based fibers embedding carbon dots with anti‐bacterial and fluorescent properties

Polymer Composites ◽

10.1002/pc.25872 ◽

2020 ◽

Author(s):

Saliha B. Kurt ◽

Nurettin Sahiner

Keyword(s):

Carbon Dots ◽

Fluorescent Properties

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Electrospinning Highly Concentrated Sodium Alginate Nanofibres without Surfactants by Adding Fluorescent Carbon Dots

Nanomaterials ◽

10.3390/nano10030565 ◽

2020 ◽

Vol 10 (3) ◽

pp. 565 ◽

Cited By ~ 2

Author(s):

Junke Yu ◽

Zhihui Zhao ◽

Jianxin Sun ◽

Cunzhen Geng ◽

Qingxu Bu ◽

...

Keyword(s):

Electron Microscopy ◽

Sodium Alginate ◽

Carbon Dots ◽

In Vitro Cytotoxicity ◽

Fluorescent Properties ◽

Cytotoxicity Assessment ◽

Fluorescent Carbon Dots ◽

Scanning Electron ◽

Fluorescent Carbon

In this study, sodium alginate (SA) nanofibres were obtained by electrospinning via the assistance of traditional poly(ethyl oxide) (PEO) and dimethyl sulfoxide (DMSO) with a high SA/PEO ratio of up to 94:6. However, surfactants with more or less toxicities were replaced by nontoxic and fluorescent carbon dots (CDs) to improve spinnability. Experimental details were conducted by fixing the ratio of SA/PEO to 90:10. Then, the electrospinning products of solutions with different compositions were observed with scanning electron microscopy. Properties such as conductivity, surface tension and rheology of the solutions were investigated to determine the key influencing factors. Moreover, since CDs have excellent fluorescence properties, the fluorescent properties of the nanofibre membrane that was blended with CDs were then collected. In addition, in vitro cytotoxicity assessment of the nanofibres were conducted to evaluate the toxicities and biocompatibility.

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Multicolorful Carbon Dots for Tumor Theranostics

Current Medicinal Chemistry ◽

10.2174/0929867324666170316110810 ◽

2018 ◽

Vol 25 (25) ◽

pp. 2894-2909 ◽

Cited By ~ 10

Author(s):

Haitao Wang ◽

Jingran Bi ◽

Bei-Wei Zhu ◽

Mingqian Tan

Keyword(s):

Cancer Progression ◽

Carbon Dots ◽

Carbon Nanostructures ◽

Volume Ratio ◽

The Body ◽

Cancer Drug ◽

Fluorescent Properties ◽

Cancer Theranostics ◽

Cancer Drug Delivery ◽

Tumor Theranostics

Background: Cancer is a great threat of human health worldwide due to the uncontrollable spread of malignant cells throughout the body. Accurate diagnosis and targeted therapy approaches are critical factors for cancer treatment. Combination of therapeutic and diagnostic agents in a single nanocarrier enables to simultaneously monitor the cancer progression and tune disease therapy with minimum side effect. Objective: Carbon dots are a novel class of small fluorescence carbon nanostructures with size less than 10 nm at least in one dimension, which exhibit excellent optical properties, larger surface area to volume ratio and low toxicity. The unique properties of carbon dots make it as an ideal carrier for incorporation of cancer targeting moieties, bio-imaging agents and antineoplastic agents in one delivery system. Methods: An literature search was conducted using Web of Science to find out articles related to carbon dots and tumor theranostics. Results: Numerous applications of carbon dots in cancer theranostics have been reported during the past 10 years. This review introduces a brief history and basic fluorescent properties of carbon dots, and then discusses synthesis strategies and applications of carbon dots in biological imaging, targeted anti-cancer drug delivery, photodynamic therapy, photothermal therapy as well as gene delivery for cancer theranostics. Future directions of carbon dots in cancer theranostics are also highlighted.

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Fluorescent Carbon Dots and their Applications in Sensing of Small Organic Molecules

Current Analytical Chemistry ◽

10.2174/1573411017999210120180236 ◽

2021 ◽

Vol 17 ◽

Author(s):

Sakib Hussain Laghari ◽

Najma Memon ◽

Muhammad Yar Khuhawer ◽

Taj Muhammad Jahangir

Keyword(s):

Small Molecules ◽

Fluorescent Probes ◽

Carbon Dots ◽

Organic Molecules ◽

Fluorescent Properties ◽

Small Organic Molecules ◽

Uv Visible ◽

Size Of Particles ◽

Fluorescent Carbon Dots ◽

Fluorescent Carbon

Background: Fluorescence-based sensing is considered highly sensitive and fluorescent probes with improved properties are always desired. Fluorescent carbon dots (CDs) are newly emerging quasi-spherical nanoparticles of less than 10 nm in size and belong to the carbon nano-material’s family. CDs have great potential as fluorescent probes and currently are under open deliberation by the researchers due to their striking properties such as low environmental hazard, high selectivity, greater sensitivity, good biocompatibility, tunable fluorescent properties and excitation dependent multicolor emission behavior. Introduction: This review demonstrates various available methods for fabrication of fluorescent CDs, capping of CDs and characterization with various techniques including UV-visible, FT-IR, and TEM. Analytical applications using CDs for the sensing of small organic molecules, specifically nitroaromatic compounds in the environmental samples are complied. Methods: The review covers literature related to synthesis and characterization of carbon dots. It includes around 171 research articles in this field. Results: Carbon dots can be synthesized using numerous routes. In all cases CDs possess spectral properties with little variation in wavelength maxima. Optical properties of CDs can be tuned by compositing these with metallic quantum dots or by modifying their surface with desired functionalities. HR-TEM is needed to see the morphology and size of particles whereas UV-Visible and FTIR are indispensable tools for this kind of research. These particles are successfully applied to sense small molecules in some matrices. Conclusion: Carbon dots are bright stars in fluorescent sensing of small molecules. However, more research is needed to determine small organic molecules in diversified areas of analysis.

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Green synthesis of carbon dots with down- and up-conversion fluorescent properties for sensitive detection of hypochlorite with a dual-readout assay

The Analyst ◽

10.1039/c3an01003a ◽

2013 ◽

Vol 138 (21) ◽

pp. 6551 ◽

Cited By ~ 150

Author(s):

Bangda Yin ◽

Jianhui Deng ◽

Xue Peng ◽

Qian Long ◽

Jiangna Zhao ◽

...

Keyword(s):

Green Synthesis ◽

Carbon Dots ◽

Sensitive Detection ◽

Fluorescent Properties

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Carbon dots: Discovery, structure, fluorescent properties, and applications

Green Processing and Synthesis ◽

10.1515/gps-2021-0006 ◽

2021 ◽

Vol 10 (1) ◽

pp. 134-156

Author(s):

Asmaa M. El-Shafey

Keyword(s):

Carbon Dots ◽

Carbon Nanomaterials ◽

New Technology ◽

Orange Peel ◽

Biological Imaging ◽

First Century ◽

Fluorescent Properties ◽

Orange Peel Waste ◽

Drug Synthesis ◽

Resources Conservation

Abstract Nanotechnology has become one of the most important topics since the beginning of the twenty-first century in numerous fields including drug synthesis and delivery, environmental protection, electronics manufacture, and astronomy due to their nanoscale particles and their properties. The traditional semi-quantum dots are replaced by a new category of fluorescent carbon nanomaterials. Carbon dots (CDs) have been explored in the last few years for their simple synthetic accession, good bio-consonance, and several revelation applications. This review explains the fluorescent properties of CDs in brief, giving also a background on CDs discovery, structure, and composition, as well as on nanocomposites, green synthesis, and their applications. Resources conservation can be achieved by using recycled substances for sustainable development which lead to a new technology. Fluorescent CDs synthesized from food wastes like bananas, orange peel waste, sugarcane bagasse, Trapa bispinosa peels, bread, and jaggery have several applications such as sensing, drug delivery, gene transfer, biological imaging, and food safety. In this study, we concentrate on CDs greener methods to prepare effective and biocompatible CDs.

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One Step Chemical Synthesis of Carbon Dot Based Smart Fluorescent Security Ink

Volume 5 - 2020, Issue 9 - September - International Journal of Innovative Science and Research Technology ◽

10.38124/ijisrt20sep237 ◽

2020 ◽

Vol 5 (9) ◽

pp. 219-222 ◽

Cited By ~ 1

Author(s):

Jyoti Sharma ◽

Pranav Y. Dave

Keyword(s):

Optical Properties ◽

Chemical Synthesis ◽

Structural Properties ◽

Carbon Dots ◽

Food Products ◽

Synthesis Process ◽

Fluorescent Properties ◽

Electronic Products ◽

Carbon Dot ◽

One Step

In the recent world, there are number of problems related to counterfeit of the different products. There are number of products, which can be easily duplicated by simple processes and the product is accurate and precise. Even the counterfeit of currency is also a main problem in world’s economic. There are number of sectors, which can be effected due to this reason like duplication of electronic products, duplication of food products, duplication of automobile products, duplication of currency, etc. So there are number of anti-counterfeiting technologies available in the market to prevent counterfeit problems. In this paper, it explains to prevent this type of problems with the help of carbon dot based gel formulation, which can be used in different ways. This paper describes the synthesis process and characterization analysis of carbon dot based smart fluorescent security ink to prevent the counterfeit problems. UV-Visspectrophotometer was utilized to differentiate optical properties and fluoroscpectometer was exploited to differentiate fluorescent properties of carbon dots and carbon dot based fluorescent ink. AFM and FTIR were used to analysis the structural properties of carbon dots and carbon dot based fluorescent ink

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Carbon Dot-Lanthanide Composite Based Smart Luminescent Anticounterfeiting Material

Journal of Nanoscience and Technology ◽

10.30799/jnst.314.20060402 ◽

2020 ◽

Vol 6 (4) ◽

pp. 924-927

Author(s):

Pranav Y. Dave ◽

Jyoti Sharma

Keyword(s):

Carbon Dots ◽

Product Category ◽

Spare Parts ◽

Luminescent Materials ◽

Fluorescent Properties ◽

Research Article ◽

One Step ◽

Ft Ir ◽

Counterfeit Products ◽

Human Desire

In this emerging technology world, the counterfeit of products are increasing due to raising the economy of industry. Counterfeiting is as old as the human desire to create objects of value. There are number of products, which can be easily duplicated by simple processes and the product is accurate and precise. Counterfeit is a problem of product security, the rise and affects every product category from consumer goods to medicines and spare parts. Products can furthermore contain non-active or even toxic- ingredients. So, luminescent materials are useful to detect different counterfeit products at different wavelength. The carbon dots-lanthanide composite based gel formulation is used to coat on different subtract and according to the process their different characterization part for the prevention of counterfeit problems. Carbon dots-lanthanide composites are basically easy to synthesis and they have fluorescent property, which can help to make product unique and diverse. With help of UV chamber, the carbon dots-lanthanide composites are easily detected at some particular wavelength. So by using this property, the gel formulation can be fabricated to coat on different subtract and characterize different surface morphology for the future precepts. UV-Vis- spectrophotometer was utilized to differentiate optical properties and fluorospectrometer was exploited to differentiate fluorescent properties of carbon dots, carbon dots-lanthanide composite and CDs-lanthanide based fluorescent ink. FT-IR and viscometer were used characterized other properties of carbon dots-lanthanide based fluorescent ink. This research article is the revised article of one step synthesis of carbon dots based smart fluorescent security ink.

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