The scalability in the mechanochemical syntheses of edge functionalized graphene materials and biomass-derived chemicals

2014 ◽  
Vol 170 ◽  
pp. 223-233 ◽  
Author(s):  
Richard G. Blair ◽  
Katerina Chagoya ◽  
Scott Biltek ◽  
Steven Jackson ◽  
Ashlyn Sinclair ◽  
...  
Keyword(s):  
Chemical Synthesis ◽  
Value Added ◽  
Discrete Element ◽  
Reactor Design ◽  
Laboratory Scale ◽  
Reaction Pathways ◽  
Functionalized Graphene ◽  
Thermal Monitoring ◽  
Crucial Step ◽  
Impact Forces

Mechanochemical approaches to chemical synthesis offer the promise of improved yields, new reaction pathways and greener syntheses. Scaling these syntheses is a crucial step toward realizing a commercially viable process. Although much work has been performed on laboratory-scale investigations little has been done to move these approaches toward industrially relevant scales. Moving reactions from shaker-type mills and planetary-type mills to scalable solutions can present a challenge. We have investigated scalability through discrete element models, thermal monitoring and reactor design. We have found that impact forces and macroscopic mixing are important factors in implementing a truly scalable process. These observations have allowed us to scale reactions from a few grams to several hundred grams and we have successfully implemented scalable solutions for the mechanocatalytic conversion of cellulose to value-added compounds and the synthesis of edge functionalized graphene.

Light-driven reduction of carbon dioxide: Altering the reaction pathways and designing photocatalysts toward value-added and renewable fuels

2021 ◽  
Vol 237 ◽  
pp. 116547
Author(s):  
Quyet Van Le ◽  
Van-Huy Nguyen ◽  
Trinh Duy Nguyen ◽  
Ajit Sharma ◽  
Gul Rahman ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Value Added ◽  
Reaction Pathways ◽  
Renewable Fuels

scholarly journals Validation of Particle Size Segregation of Sintered Ore during Flowing through Laboratory-scale Chute by Discrete Element Method

2008 ◽  
Vol 48 (12) ◽  
pp. 1696-1703 ◽  
Author(s):  
Hiroshi Mio ◽  
Satoshi Komatsuki ◽  
Masatoshi Akashi ◽  
Atsuko Shimosaka ◽  
Yoshiyuki Shirakawa ◽  
...  
Keyword(s):  
Particle Size ◽  
Discrete Element Method ◽  
Discrete Element ◽  
Laboratory Scale ◽  
Size Segregation ◽  
Element Method

scholarly journals Recent Advances in Photocatalytic Transformation of Carbohydrates Into Valuable Platform Chemicals

2021 ◽  
Vol 3 ◽  
Author(s):  
Huan Chen ◽  
Kun Wan ◽  
Fangjuan Zheng ◽  
Zhuo Zhang ◽  
Hongyu Zhang ◽  
...  
Keyword(s):  
Solar Energy ◽  
Scientific Community ◽  
Value Added ◽  
Reaction Pathways ◽  
Future Perspective ◽  
Reaction Conditions ◽  
Catalytic Systems ◽  
Selective Transformation ◽  
Platform Chemicals ◽  
Broad Interest

In response to the less accessible fossil resources and deteriorating environmental problems, catalytic conversion of the abundant and renewable lignocellulosic biomass to replace fossil resources for the production of value-added chemicals and fuels is of great importance. Depolymerization of carbohydrate and its derivatives can obtain a series of C5-C6 monosaccharides (e.g., glucose and xylose) and their derived platform compounds (e.g., HMF and furfural). Selective transformation of lignocellulose using sustainable solar energy via photocatalysis has attract broad interest from a growing scientific community. The unique photogenerated reactive species (e.g., h+, e−, •OH, •O2−, and 1O2), novel reaction pathways as well as the mild reaction conditions make photocatalysis a “dream reaction.” This review is aimed to provide an overview of the up-to-date contributions achieved in the selective photocatalytic transformation of carbohydrate and its derivatives. Photocatalytic methods, properties and merits of different catalytic systems are well summarized. We then put forward future perspective and challenges in this field.

scholarly journals Exploiting xylan as sugar donor for the synthesis of an antiproliferative xyloside using an enzyme cascade

2019 ◽  
Vol 18 (1) ◽  
Author(s):  
Manuel Nieto-Domínguez ◽  
José Alberto Martínez-Fernández ◽  
Beatriz Fernández de Toro ◽  
Juan A. Méndez-Líter ◽  
Francisco Javier Cañada ◽  
...  
Keyword(s):  
Chemical Synthesis ◽  
Biomass Conversion ◽  
Value Added ◽  
Cost Effective ◽  
Raw Material ◽  
Birchwood Xylan ◽  
Enzyme Cascade ◽  
Antiproliferative Agent ◽  
Xylanolytic Enzymes ◽  
Value Added Products

Abstract Background Currently, industrial societies are seeking for green alternatives to conventional chemical synthesis. This demand has merged with the efforts to convert lignocellulosic biomass into value-added products. In this context, xylan, as one of main components of lignocellulose, has emerged as a raw material with high potential for advancing towards a sustainable economy. Results In this study, the recombinant endoxylanase rXynM from the ascomycete Talaromyces amestolkiae has been heterologously expressed in Pichia pastoris and used as one of the catalysts of an enzyme cascade developed to synthesize the antiproliferative 2-(6-hydroxynaphthyl) β-d-xylopyranoside, by transglycosylation of 2,6-dihydroxynaphthalene. The approach combines the use of two fungal xylanolytic enzymes, rXynM and the β-xylosidase rBxTW1 from the same fungus, with the cost-effective substrate xylan. The reaction conditions for the cascade were optimized by a Central Composite Design. Maximal productions of 0.59 and 0.38 g/L were reached using beechwood xylan and birchwood xylan, respectively. For comparison, xylans from other sources were tested in the same reaction, suggesting that a specific optimization is required for each xylan variety. The results obtained using this enzyme cascade and xylan were similar or better to those previously reported for a single catalyst and xylobiose, an expensive sugar donor. Conclusions Beechwood and birchwood xylan, two polysaccharides easily available from biomass, were used in a novel enzyme cascade to synthetize an antiproliferative agent. The approach represents a green alternative to the conventional chemical synthesis of 2-(6-hydroxynaphthyl) β-d-xylopyranoside using a cost-effective substrate. The work highlights the role of xylan as a raw material for producing value-added products and the potential of fungal xylanolytic enzymes in the biomass conversion.

scholarly journals Synthesis of novel WO3/ZrSiO4 catalysts for dehalogenation of halogenated hydrocarbons

10.30544/411 ◽  
2019 ◽  
Vol 25 (1) ◽  
pp. 31-37
Author(s):  
Vesna Nikolic ◽  
Željko Kamberović ◽  
Milisav Ranitović ◽  
Milorad Gavrilovski ◽  
Zoran Anđić
Keyword(s):  
Phase Composition ◽  
Water Vapor ◽  
Environmental Impact ◽  
Chemical Synthesis ◽  
Xrd Analysis ◽  
Production Method ◽  
Laboratory Scale ◽  
Halogenated Hydrocarbons ◽  
Synthesis Routes ◽  
Novel Catalyst

This research aimed to develop a novel catalyst based on WO3/ZrSiO4 system for halogenated hydrocarbons processing. The production method of this catalyst involved extrusion and as such was simplified compared to thermo-chemical synthesis routes. It had a reduced number of process stages and a lower environmental impact at the same time. In order to examine the phase composition of the catalyst after sintering at 800 °C, the XRD analysis was carried out. The catalyst was then tested in chlorodifluoromethane dehalogenation process on laboratory scale at temperatures of 300, 400 and 500 °C in the presence of water vapor. Catalyst achieves high dehalogenation efficiencies of 88.6, 95.9, and 99.5 % for each of the process temperatures, respectively. Obtained results are in the range with those achieved by using thermo-chemically prepared dehalogenation catalysts.

scholarly journals Whole-Cell Biotransformation of 1,12-Dodecanedioic Acid from Coconut Milk Factory Wastewater by Recombinant CYP52A17SS Expressing Saccharomyces cerevisiae

Processes ◽  
2020 ◽  
Vol 8 (8) ◽  
pp. 969
Author(s):  
Phawadee Buathong ◽  
Nassapat Boonvitthya ◽  
Gilles Truan ◽  
Warawut Chulalaksananukul
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Fatty Acids ◽  
Cytochrome P450 ◽  
Chemical Synthesis ◽  
Value Added ◽  
Coconut Milk ◽  
Biological Synthesis ◽  
Cytochrome P450 Enzyme ◽  
Yeast Growth ◽  
Dodecanedioic Acid

Biotransformation of fatty acids from renewable wastewater as feedstock to value-added chemicals is a fascinating commercial opportunity. α,ω-Dicarboxylic acids (DCAs) are building blocks in many industries, such as polymers, cosmetic intermediates, and pharmaceuticals, and can be obtained by chemical synthesis under extreme conditions. However, biological synthesis can replace the traditional chemical synthesis using cytochrome P450 enzymes to oxidize fatty acids to DCAs. Saccharomyces cerevisiae BY(2R)/pYeDP60-CYP52A17SS (BCM), a transgenic strain expressing the galactose-inducible CYP52A17SS cytochrome P450 enzyme, was able to grow in a coconut milk factory wastewater (CCW) medium and produced 12-hydroxydodecanoic acid (HDDA) and 1,12-dodecanedioic acid (DDA). The supplementation of CCW with 10 g/L yeast extract and 20 g/L peptone (YPCCW) markedly increased the yeast growth rate and the yields of 12-HDDA and 1,12-DDA, with the highest levels of approximately 60 and 38 µg/L, respectively, obtained at 30 °C and pH 5. The incubation temperature and medium pH strongly influenced the yeast growth and 1,12-DDA yield, with the highest 1,12-DDA formation at 30 °C and pH 5–5.5. Hence, the S. cerevisiae BCM strain can potentially be used for producing value-added products from CCW.

Ultrasound assisted ZnO coating in a microflow based photoreactor for selective oxidation of benzyl alcohol to benzaldehyde

2019 ◽  
Vol 21 (6) ◽  
pp. 1241-1246 ◽  
Author(s):  
Vaishakh Nair ◽  
Juan Carlos Colmenares ◽  
Dmytro Lisovytskiy
Keyword(s):  
Green Chemistry ◽  
Benzyl Alcohol ◽  
Selective Oxidation ◽  
Value Added ◽  
Reactor Design ◽  
Heterogeneous Photocatalysis ◽  
Oxidation Of Benzyl Alcohol ◽  
Ultrasound Assisted

Heterogeneous photocatalysis in a microflow system for generation of value added chemicals is a novel green chemistry approach requiring the understanding of photocatalysis, microfluidics and reactor design.

LCA Application to Chemical Synthesis at Laboratory Scale

2020 ◽  
pp. 101-123 ◽  
Author(s):  
Martina Pini ◽  
Roberto Rosa ◽  
Paolo Neri ◽  
Anna Maria Ferrari
Keyword(s):  
Chemical Synthesis ◽  
Laboratory Scale

scholarly journals Microbial Transformation of Sesquiterpenoids

2009 ◽  
Vol 4 (8) ◽  
pp. 1934578X0900400 ◽  
Author(s):  
Haq N Bhatti ◽  
Muhammad Zubair ◽  
Nasir Rasool ◽  
Zahid Hassan ◽  
Viqar U Ahmad
Keyword(s):  
Natural Products ◽  
Biological Activity ◽  
New Products ◽  
Microbial Transformation ◽  
Value Added ◽  
Reaction Pathways ◽  
Agricultural Chemicals ◽  
Remote Sites ◽  
Pharmaceutical Industries ◽  
Value Added Products

Biotransformations are useful methods for producing medicinal and agricultural chemicals from both active and inactive natural products with the introduction of chemical functions into remote sites of the molecules. Research on microbial biotransformations of commonly available sesquiterpenoids into more valuable derivatives has always been of interest because of their economical potential to the perfume, food, chemical and pharmaceutical industries. Fungal transformations of sesquiterpenoids have been less frequently studied compared with many other natural products. In recent years, however, much attention has been given to the exploitation of new products with enhanced biological activity using microorganisms. This review, covering the period from 1990 to 2006, summarizes our knowledge of the biotransformations of sesquiterpenoids by various fungi. Such transformations could lead to the discovery of new reaction pathways that might be useful in the design of new value-added products.

Sign in / Sign up

Export Citation Format

Share Document