Cheese ‘refinement’ with whey B-vitamin removal during precipitation potentially induces temporal ‘functional’ dietary shortage: homocysteine as a biomarker

2014 ◽  
Vol 5 (7) ◽  
pp. 1587-1593 ◽  
Author(s):  
N. Shapira
Keyword(s):  

Cheese ‘refinement’ with massive B-vitamin losses (≈70–84%) through whey removal during precipitation may potentially induce a temporal imbalance between protein/methionine load and episodic/shortage of nutrients critical for their metabolism,i.e.B6 and B12.


2011 ◽  
Vol 81 (4) ◽  
pp. 240-244 ◽  
Author(s):  
Mary Ward ◽  
Carol P Wilson ◽  
J J Strain ◽  
Geraldine Horigan ◽  
John M. Scott ◽  
...  

Hypertension is a leading risk factor for cardiovascular disease (CVD) and stroke. A common polymorphism in the gene encoding the enzyme methylenetetrahydrofolate reductase (MTHFR), previously identified as the main genetic determinant of elevated homocysteine concentration and also recognized as a risk factor for CVD, appears to be independently associated with hypertension. The B-vitamin riboflavin is required as a cofactor by MTHFR and recent evidence suggests it may have a role in modulating blood pressure, specifically in those with the homozygous mutant MTHFR 677 TT genotype. If studies confirm that this genetic predisposition to hypertension is correctable by low-dose riboflavin, the findings could have important implications for the management of hypertension given that the frequency of this polymorphism ranges from 3 to 32 % worldwide.



1949 ◽  
Vol 8 (4) ◽  
pp. 518-523 ◽  
Author(s):  
W. N. McMillen ◽  
R. W. Luecke ◽  
F. Thorp


2019 ◽  
Vol 15 (68) ◽  
pp. 082 ◽  
Author(s):  
V. P. Mischenko ◽  
I. V. Rudenko ◽  
V. K. Likhachov ◽  
M. Y. Golubenko ◽  
L. M. Dobrovolska


2003 ◽  
Vol 133 (11) ◽  
pp. 3636-3642 ◽  
Author(s):  
Xiang Gao ◽  
Manjiang Yao ◽  
Megan A. McCrory ◽  
Guansheng Ma ◽  
Yanping Li ◽  
...  


Proceedings ◽  
2019 ◽  
Vol 8 (1) ◽  
pp. 19
Author(s):  
Nicola Gillies ◽  
Amber M. Milan ◽  
Pankaja Sharma ◽  
Brenan Durainayagam ◽  
Sarah M. Mitchell ◽  
...  

Background: Maintaining optimal status of folate and metabolically [...]



2008 ◽  
Vol 4 ◽  
pp. T701-T701
Author(s):  
Lawrence J. Whalley ◽  
Kellie Rance ◽  
Susan Duthie ◽  
Helen Fox ◽  
John Starr ◽  
...  


1997 ◽  
Vol 87 (4) ◽  
pp. 411-416 ◽  
Author(s):  
Teresa B. Domagala ◽  
Magdalena Libura ◽  
Andrzej Szczeklik


Author(s):  
Aviva Fattal-Valevski

Thiamine (vitamin B1) was the first B vitamin to have been identified. It serves as a cofactor for several enzymes involved in energy metabolism. The thiamine-dependent enzymes are important for the biosynthesis of neurotransmitters and for the production of reducing substances used in oxidant stress defenses, as well as for the synthesis of pentoses used as nucleic acid precursors. Thiamine plays a central role in cerebral metabolism. Its deficiency results in dry beriberi, a peripheral neuropathy, wet beriberi, a cardiomyopathy with edema and lactic acidosis, and Wernicke—Korsakoff syndrome, whose manifestations consist of nystagmus, ophthalmoplegia, and ataxia evolving into confusion, retrograde amnesia, cognitive impairment, and confabulation. Patients on a strict thiamine-deficient diet display a state of severe depletion within 18 days. The most common cause of thiamine deficiency in affluent countries is either alcoholism or malnutrition in nonalcoholic patients. Treatment by thiamine supplementation is beneficial for diagnostic and therapeutic purposes.



1964 ◽  
Vol 29 (5) ◽  
pp. 690-691 ◽  
Author(s):  
JOHN H. LITCHFIELD


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