Retracted Article: The next generation cell-penetrating peptide and carbon dot conjugated nano-liposome for transdermal delivery of curcumin

2016 ◽  
Vol 4 (3) ◽  
pp. 418-429 ◽  
Author(s):  
Santanu Patra ◽  
Ekta Roy ◽  
Rashmi Madhuri ◽  
Prashant K. Sharma
Keyword(s):  
Drug Delivery ◽  
Transdermal Delivery ◽  
Transdermal Drug Delivery ◽  
Circulation Time ◽  
Cell Penetrating Peptide ◽  
Next Generation ◽  
Carbon Dot ◽  
Cell Penetrating ◽  
Retracted Article ◽  
Enhanced Stability

Novel polyarginine-conjugated C dot modified spherical nano-liposomes with enhanced stability, long circulation time and high cytocompatibility are successfully prepared and investigated for transdermal drug delivery.

scholarly journals Retraction: The next generation cell-penetrating peptide and carbon dot conjugated nano-liposome for transdermal delivery of curcumin

2019 ◽  
Vol 7 (1) ◽  
pp. 442-442 ◽  
Author(s):  
Neil Hammond
Keyword(s):  
Transdermal Delivery ◽  
Cell Penetrating Peptide ◽  
Next Generation ◽  
Carbon Dot ◽  
Cell Penetrating

Retraction of ‘The next generation cell-penetrating peptide and carbon dot conjugated nano-liposome for transdermal delivery of curcumin’ by Santanu Patra et al., Biomater. Sci., 2016, 4, 418–429.

scholarly journals Enhancement strategies for transdermal drug delivery systems: current trends and applications

2021 ◽  
Author(s):  
Delly Ramadon ◽  
Maeliosa T. C. McCrudden ◽  
Aaron J. Courtenay ◽  
Ryan F. Donnelly
Keyword(s):  
Drug Delivery ◽  
Stratum Corneum ◽  
Transdermal Delivery ◽  
Transdermal Drug Delivery ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Global Market ◽  
Therapeutic Drug ◽  
Current Trends ◽  
Transdermal Drug Delivery Systems

AbstractTransdermal drug delivery systems have become an intriguing research topic in pharmaceutical technology area and one of the most frequently developed pharmaceutical products in global market. The use of these systems can overcome associated drawbacks of other delivery routes, such as oral and parenteral. The authors will review current trends, and future applications of transdermal technologies, with specific focus on providing a comprehensive understanding of transdermal drug delivery systems and enhancement strategies. This article will initially discuss each transdermal enhancement method used in the development of first-generation transdermal products. These methods include drug/vehicle interactions, vesicles and particles, stratum corneum modification, energy-driven methods and stratum corneum bypassing techniques. Through suitable design and implementation of active stratum corneum bypassing methods, notably microneedle technology, transdermal delivery systems have been shown to deliver both low and high molecular weight drugs. Microneedle technology platforms have proven themselves to be more versatile than other transdermal systems with opportunities for intradermal delivery of drugs/biotherapeutics and therapeutic drug monitoring. These have shown that microneedles have been a prospective strategy for improving transdermal delivery systems. Graphical abstract

scholarly journals The Use of Sonophoresis in the Administration of Drugs Throughout the Skin

2009 ◽  
Vol 12 (1) ◽  
pp. 88 ◽  
Author(s):  
Jose Juan Escobar-Chavez ◽  
Dalia Bonilla-Martínez ◽  
Martha Angélica Villegas-González ◽  
Isabel Marlen Rodríguez-Cruz ◽  
Clara Luisa Domínguez-Delgado
Keyword(s):  
Drug Delivery ◽  
Drug Release ◽  
Oral Administration ◽  
Transdermal Delivery ◽  
Transdermal Drug Delivery ◽  
Drug Delivery Systems ◽  
Medical Diagnostics ◽  
Attractive Alternative ◽  
Delivery Methods ◽  
Conventional Drug

Abstract Transdermal drug delivery offers an attractive alternative to the conventional drug delivery methods of oral administration and injection. However, the stratum corneum acts as a barrier that limits the penetration of substances through the skin. Application of ultrasound to the skin increases its permeability (sonophoresis) and enables the delivery of various substances into and through the skin. Ultrasound has been used extensively for medical diagnostics and to a certain extent in medical therapy (physiotherapy, ultrasonic surgery, hyperthermia). Nevertheless, it has only recently become popular as a technique to enhance drug release from drug delivery systems. A number of studies suggest the use of ultrasound as an external mean of delivering drugs at increased rates and at desired times. This review presents the main findings in the field of sonophoresis, namely transdermal drug delivery and transdermal monitoring. Particular attention is paid to proposed enhancement mechanisms and trends in the field of topical and transdermal delivery.

scholarly journals SPA: a peptide antagonist that acts as a cell-penetrating peptide for drug delivery

Drug Delivery ◽  
2019 ◽  
Vol 27 (1) ◽  
pp. 91-99
Author(s):  
Jingjing Song ◽  
Sujie Huang ◽  
Zhengzheng Zhang ◽  
Bo Jia ◽  
Huan Xie ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cell Penetrating Peptide ◽  
Cell Penetrating ◽  
A Cell ◽  
Peptide Antagonist

Quantifying molecular partition of cell-penetrating peptide-cargo supramolecular complexes into lipid membranes: optimizing peptide-based drug delivery systems

2013 ◽  
Vol 19 (4) ◽  
pp. 182-189 ◽  
Author(s):  
João Miguel Freire ◽  
Ana Salomé Veiga ◽  
Beatriz G. de la Torre ◽  
David Andreu ◽  
Miguel A. R. B. Castanho
Keyword(s):  
Drug Delivery ◽  
Lipid Membranes ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Supramolecular Complexes ◽  
Cell Penetrating Peptide ◽  
Cell Penetrating

scholarly journals Derma rollers in therapy: the transition from cosmetics to transdermal drug delivery

2020 ◽  
Vol 22 (4) ◽  
Author(s):  
Leonna Dsouza ◽  
Vivek M. Ghate ◽  
Shaila A. Lewis
Keyword(s):  
Drug Delivery ◽  
Stratum Corneum ◽  
Transdermal Delivery ◽  
Transdermal Drug Delivery ◽  
Hair Follicles ◽  
Collagen Production ◽  
Site Of Action

AbstractDerma roller, a device rolled onto the skin to form micropores, is extensively used for cosmetic purposes. The pores thus created are utilized to either result in the induction of collagen production, leading to glowing and wrinkle-free skin or for permeating the applied formulations to the site of action within the skin. Recent studies have shown the benefits of using derma rollers for transdermal delivery of drugs. In the nascent stage, this approach paves a way to successfully breach the stratum corneum and aid in the movement of medications directed towards the dermis and the hair follicles. The review essentially summarizes the evidence of the use of derma rollers in cosmetic setup, their designing, and the preclinical and clinical reports of efficacy, safety, and concerns when translated for pharmaceutical purposes and transdermal drug delivery.

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