Synthesis of amphiphilic polysuccinimide star copolymers for responsive delivery in plants

2015 ◽  
Vol 51 (47) ◽  
pp. 9694-9697 ◽  
Author(s):  
Mingsheng Chen ◽  
Shaun P. Jensen ◽  
Megan R. Hill ◽  
Gloria Moore ◽  
Zhenli He ◽  
...  
Keyword(s):  
Controlled Release ◽  
Plant Cells ◽  
Delivery Methods ◽  
Site Specific ◽  
Star Copolymers ◽  
Novel Methods

While polymeric nano-carriers are widely used in medicine for controlled release and site-specific delivery, few reports have applied such delivery methods within agriculture. We report the synthesis of polymeric nano-carriers designed for delivery to the phloem of plants and describe novel methods for evaluating toxicity of polymers in plant cells.

Liposomes and immunoliposomes for controlled release or site specific delivery of anti-parasitic drugs and cytostatics

1991 ◽  
Vol 16 (1-2) ◽  
pp. 147-154 ◽  
Author(s):  
D.J.A. Crommelin ◽  
W.M.C. Eling ◽  
P.A. Steerenberg ◽  
U.K. Nässander ◽  
G. Storm ◽  
...  
Keyword(s):  
Controlled Release ◽  
Site Specific

Using molasses as an alternative to controlled release devices for administering n-alkane markers to cattle

2003 ◽  
Vol 76 (3) ◽  
pp. 471-480 ◽  
Author(s):  
R. E. Hendricksen ◽  
C. Gazzola ◽  
M. M. Reich ◽  
R. F. Roberton ◽  
D. J. Reid ◽  
...  
Keyword(s):  
Controlled Release ◽  
Block Design ◽  
Extended Period ◽  
Control Treatment ◽  
Delivery Methods ◽  
Dry Matter Digestibility ◽  
Release Device ◽  
Randomized Complete Block Design ◽  
The Individual ◽  
Release Devices

AbstractAn experiment was conducted to determine if molasses could be successfully used to administer dotriacontane (C32) and hexatriacontane (C36) n-alkane markers to steers and to compare this method with a commercially available intra-ruminal controlled release device (CRD). The experiment was conducted over two similar periods (runs) using 24 Brahman crossbred steers in each run to study the effect of marker delivery methods and tropical grass hay diets in a randomized complete block design with three replicates. All steers were housed individually in partially covered pens, received one of two buffel-grass hays (B20: 20-week regrowth; 0·72 g nitrogen (N) per 100 g and B8: 8-week regrowth; 1·11 g N per 100 g) and one of four marker delivery treatments (control: no marker; 200 mg/day of C32 and C36 n-alkanes from a CRD or offered three times (Ms ✕ 3) or five times (Ms ✕ 5) a day in molasses). Voluntary intake (VI) and dry matter digestibility (DMD) for diets differed (P < 0·001) with B8 greater than B20. There was no difference among marker treatments for VI but the control treatment had greater, unexplained and possibly spurious, DMD than the Ms ✕ 3 marker treatment. Although the recovery of n-alkanes was variable (0·84 to 1·05) adjacent odd- and even-chain n-alkanes were similar with no differences (P > 0·05) due to marker treatment or diet. The CRD supplied a consistent marker dose between 6 and 18 days after insertion. Deviation from the 24-h mean faecal concentration seldom varied more than 0·03 for the individual markers and 0·05 for C31/C32 and C33/C32 ratios for all treatments. Over all the n-alkanes studied, the between-day variation was less than the within-day variation. For instance, the average of subsamples taken at 06:00 h and 18:00 h was within proportionately 0·05 of the 10-day mean concentration for 0·38 and 0·25 of records for C32 and C36 markers, respectively. It was concluded that molasses containing C32 and C36 n-alkane markers and given either three or five times daily was as accurate as the commercial CRD in administering n-alkane markers to steers and provides a method of delivering n-alkanes over an extended period in grazing studies.

scholarly journals Development of delivery methods for carbohydrate-based drugs: controlled release of biologically-active short chain fatty acid-hexosamine analogs

2010 ◽  
Vol 27 (4) ◽  
pp. 445-459 ◽  
Author(s):  
Udayanath Aich ◽  
M. Adam Meledeo ◽  
Srinivasa-Gopalan Sampathkumar ◽  
Jie Fu ◽  
Mark B. Jones ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Controlled Release ◽  
Short Chain Fatty Acid ◽  
Chain Fatty Acid ◽  
Biologically Active ◽  
Short Chain ◽  
Delivery Methods

scholarly journals A review on the important phytochemicals and their role in psoriasis

2021 ◽  
Vol 13 (3) ◽  
pp. 880-896
Author(s):  
Ashish Pandey ◽  
Alok Kumar Shukla ◽  
Ramesh Chandra Dubey ◽  
Ravi Pratap
Keyword(s):  
Skin Disease ◽  
Geographic Location ◽  
Inflammatory Skin Disease ◽  
Delivery Methods ◽  
Disease Treatment ◽  
Site Specific ◽  
Target Sites ◽  
Herbal Therapies ◽  
Aloe Emodin ◽  
Environmental Causes

Psoriasis may emerge at any stage of life irrespective of age, sex or geographic location. It is identified as a chronic immune-linked inflammatory skin disease that affects all human races. Psoriasis is often more Caucasian than non-Caucasian groups of human races and in geographic areas, like higher latitudes and Western countries. Therefore, attention should be paid to both genetic and environmental causes of psoriasis. Natural products have significantly contributed and encouraged the advances in skin disease treatment like psoriasis. The maximum number of phytochemicals is now being used worldwide, including various plants, herbs, and formulations. In addition, some phytochemicals like psoralen, aloe-emodin, curcumin etc. have also been isolated in pure form and have also shown their efficacy in the management of psoriasis. The presence of such phytochemicals confirms the effectiveness of few herbal therapies. This paper reviews some of the promising phytochemicals and their potential molecular target sites and mechanism of action, which may aid in designing and producing more precise and selective antipsoriatic agents. Exploring and recognizing phytochemicals as to how they function will facilitate more site-specific delivery methods for psoriasis care.

pH-sensitive inulin-based nanomicelles for intestinal site-specific and controlled release of celecoxib

2018 ◽  
Vol 181 ◽  
pp. 570-578 ◽  
Author(s):  
Delia Mandracchia ◽  
Adriana Trapani ◽  
Sara Perteghella ◽  
Milena Sorrenti ◽  
Laura Catenacci ◽  
...  
Keyword(s):  
Controlled Release ◽  
Ph Sensitive ◽  
Site Specific
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