scholarly journals The association and aggregation of the metamorphic chemokine lymphotactin with fondaparinux: from nm molecular complexes to μm molecular assemblies

2016 ◽  
Vol 52 (2) ◽  
pp. 394-397 ◽  
Author(s):  
Sophie R. Harvey ◽  
Cait E. MacPhee ◽  
Brian F. Volkman ◽  
Perdita E. Barran
Keyword(s):  
Electron Microscopy ◽  
Mass Spectrometry ◽  
Transmission Electron Microscopy ◽  
Ion Mobility ◽  
Drift Tube ◽  
Molecular Complexes ◽  
Ion Mobility Mass Spectrometry ◽  
Molecular Assemblies ◽  
Transmission Electron

Transmission electron microscopy and drift tube ion mobility-mass spectrometry are used to study the assemblies formed by the metamorphic chemokine lymphotactin in the presence of a model glycosaminoglycan.

scholarly journals EM∩IM: software for relating ion mobility mass spectrometry and electron microscopy data

The Analyst ◽  
2016 ◽  
Vol 141 (1) ◽  
pp. 70-75 ◽  
Author(s):  
Matteo T. Degiacomi ◽  
Justin L. P. Benesch
Keyword(s):  
Electron Microscopy ◽  
Mass Spectrometry ◽  
Structural Biology ◽  
Cross Sections ◽  
Ion Mobility ◽  
Ion Mobility Mass Spectrometry ◽  
Density Maps ◽  
Transmission Electron ◽  
Microscopy Data ◽  
Means Of Transmission

EM∩IM enables the calculation of collision cross-sections from electron density maps obtained, for example, by means of transmission electron microscopy. This capability will further aid the integration of ion mobility mass spectrometry with modern structural biology.

High resolution ion mobility-mass spectrometry for separation and identification of isomeric lipids

The Analyst ◽  
2015 ◽  
Vol 140 (20) ◽  
pp. 6904-6911 ◽  
Author(s):  
M. Groessl ◽  
S. Graf ◽  
R. Knochenmuss
Keyword(s):  
Mass Spectrometry ◽  
Double Bond ◽  
High Resolution ◽  
Ion Mobility ◽  
Biological Samples ◽  
Drift Tube ◽  
Acyl Chain ◽  
Ion Mobility Mass Spectrometry

Separation and identification of isomeric species is a major challenge in lipidomics. Herein, we demonstrate that lipid isomers that differ only in position of the acyl chain, position of the double bond or double bond geometry can be distinguished using drift-tube ion mobility-mass spectrometry, even in complex biological samples.

scholarly journals In Situ Correlative Microscopy Combining Transmission Electron Microscopy and Secondary Ion Mass Spectrometry

2018 ◽  
Vol 24 (S1) ◽  
pp. 380-381 ◽  
Author(s):  
Santhana Eswara ◽  
Lluis Yedra ◽  
Alisa Pshenova ◽  
Varun Sarbada ◽  
Jean-Nicolas Audinot ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Mass Spectrometry ◽  
Transmission Electron Microscopy ◽  
Secondary Ion Mass Spectrometry ◽  
Correlative Microscopy ◽  
Transmission Electron ◽  
Ion Mass Spectrometry ◽  
Secondary Ion

scholarly journals Electron capture dissociation and drift tube ion mobility-mass spectrometry coupled with site directed mutations provide insights into the conformational diversity of a metamorphic protein

2015 ◽  
Vol 17 (16) ◽  
pp. 10538-10550 ◽  
Author(s):  
Sophie R. Harvey ◽  
Massimiliano Porrini ◽  
Robert C. Tyler ◽  
Cait E. MacPhee ◽  
Brian F. Volkman ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Electron Capture ◽  
Electron Capture Dissociation ◽  
Ion Mobility ◽  
Drift Tube ◽  
Ion Mobility Mass Spectrometry ◽  
Top Down ◽  
Conformational Diversity ◽  
Metamorphic Protein

Ion mobility mass spectrometry can be combined with data from top-down sequencing to discern adopted conformations of proteins in the absence of solvent.

Rapid Quantitation of 25-Hydroxyvitamin D2 and D3 in Human Serum Using Liquid Chromatography/Drift Tube Ion Mobility-Mass Spectrometry

2019 ◽  
Vol 91 (21) ◽  
pp. 13555-13561 ◽  
Author(s):  
Nicholas R. Oranzi ◽  
Jiajun Lei ◽  
Robin H. J. Kemperman ◽  
Christopher D. Chouinard ◽  
Brett Holmquist ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Human Serum ◽  
Ion Mobility ◽  
Drift Tube ◽  
Ion Mobility Mass Spectrometry

Petroleomics by ion mobility mass spectrometry: resolution and characterization of contaminants and additives in crude oils and petrofuels

2015 ◽  
Vol 7 (11) ◽  
pp. 4450-4463 ◽  
Author(s):  
Jandyson Machado Santos ◽  
Renan de S. Galaverna ◽  
Marcos A. Pudenzi ◽  
Eduardo M. Schmidt ◽  
Nathaniel L. Sanders ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Crude Oil ◽  
Ion Mobility ◽  
Drift Tube ◽  
Crude Oils ◽  
Ion Mobility Mass Spectrometry ◽  
Uniform Field ◽  
Field Drift

IM-MS, was performed in a new uniform-field drift tube, IM-QTOF instrument. It can resolve and characterize crude oil and its contaminants, as well as petrofuels and their additives.

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