scholarly journals Self-carried curcumin nanoparticles for in vitro and in vivo cancer therapy with real-time monitoring of drug release

Nanoscale ◽  
2015 ◽  
Vol 7 (32) ◽  
pp. 13503-13510 ◽  
Author(s):  
Jinfeng Zhang ◽  
Shengliang Li ◽  
Fei-Fei An ◽  
Juan Liu ◽  
Shubin Jin ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Drug Release ◽  
Real Time ◽  
Real Time Monitoring ◽  
Curcumin Nanoparticles ◽  
Major Attention ◽  
Pharmaceutical Agents

The use of different nanocarriers for delivering hydrophobic pharmaceutical agents to tumor sites has garnered major attention.

scholarly journals Non-invasive, real-time reporting drug release in vitro and in vivo

2015 ◽  
Vol 51 (32) ◽  
pp. 6948-6951 ◽  
Author(s):  
Yanfeng Zhang ◽  
Qian Yin ◽  
Jonathan Yen ◽  
Joanne Li ◽  
Hanze Ying ◽  
...  
Keyword(s):  
Drug Release ◽  
Real Time ◽  
Near Infrared ◽  
Reporting System ◽  
Real Time Monitoring ◽  
Near Infrared Fluorescence ◽  
Non Invasive ◽  
Fluorescence Dye

Anin vitroandin vivodrug-reporting system is developed for real-time monitoring of drug release via the analysis of the concurrently released near-infrared fluorescence dye.

Real-time monitoring of anticancer drug release in vitro and in vivo on titania nanoparticles triggered by external glutathione

Talanta ◽  
2012 ◽  
Vol 88 ◽  
pp. 631-637 ◽  
Author(s):  
Mira Kim ◽  
Ji Hye Seo ◽  
Won Il Jeon ◽  
Mi-Yeon Kim ◽  
Keunchang Cho ◽  
...  
Keyword(s):  
Drug Release ◽  
Real Time ◽  
Anticancer Drug ◽  
Titania Nanoparticles ◽  
Real Time Monitoring ◽  
Release In Vitro

Facile solvothermal synthesis of ultrathin spinel ZnMn2O4 nanospheres: An efficient electrocatalyst for in vivo and in vitro real time monitoring of H2O2

2021 ◽  
Vol 900 ◽  
pp. 115674
Author(s):  
Muthaiah Annalakshmi ◽  
Sakthivel Kumaravel ◽  
T.S.T. Balamurugan ◽  
Shen-Ming Chen ◽  
Ju-Liang He
Keyword(s):  
Real Time ◽  
Solvothermal Synthesis ◽  
Real Time Monitoring

scholarly journals NIR-Responsive Lysosomotropic Phototrigger: ʽAIE + ESIPTʼ Active Naphthalene Based Single Component Photoresponsive Nanocarrier with Two-Photon Uncaging and Real-Time Monitoring Ability

2021 ◽  
Author(s):  
Biswajit Roy ◽  
Rakesh Mengji ◽  
Samrat Roy ◽  
Bipul Pal ◽  
Avijit Jana ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Release ◽  
Real Time ◽  
Near Infrared ◽  
Single Component ◽  
Photon Absorption ◽  
Real Time Monitoring ◽  
Two Photon ◽  
Nir Light

In recent times, organelle-targeted drug delivery systems gained tremendous attention due to the site specific delivery of active drug molecules resulting in enhanced bioefficacy. In this context, the phototriggered drug delivery system (DDS) for releasing an active molecule is superior as it provides spatial and temporal control over the release. So far, near infrared (NIR) light responsive organelle targeted DDS has not yet been developed. Hence, we introduced a two-photon NIR-light responsive lysosome targeted ʽAIE + ESIPTʼ active single component DDS based on naphthalene chromophore. The Two-photon absorption cross-section of our DDS is 142 GM at 850 nm. The DDS was converted into pure organic nanoparticles for biological applications. Our nano-DDS is capable of selective targeting, AIE-luminogenic imaging, and drug release within the lysosome. In vitro studies using cancerous cell lines showed that our single component photoresponsive nanocarrier exhibited enhanced cytotoxicity and real-time monitoring ability of the drug release.

scholarly journals Linseed hydrogel based floating drug delivery system for fluoroquinolone antibiotics: Design, in vitro drug release and in vivo real-time floating detection

2020 ◽  
Vol 28 (5) ◽  
pp. 538-549 ◽  
Author(s):  
Fatima Akbar Sheikh ◽  
Muhammad Ajaz Hussain ◽  
Muhammad Umer Ashraf ◽  
Muhammad Tahir Haseeb ◽  
Muhammad Farid-ul-Haq
Keyword(s):  
Drug Delivery ◽  
Drug Release ◽  
Real Time ◽  
Drug Delivery System ◽  
In Vitro Drug Release ◽  
Floating Drug Delivery ◽  
Fluoroquinolone Antibiotics ◽  
Floating Drug Delivery System

Plasmonic CuS nanodisk assembly based composite nanocapsules for NIR-laser-driven synergistic chemo-photothermal cancer therapy

2018 ◽  
Vol 6 (7) ◽  
pp. 1035-1043 ◽  
Author(s):  
Jian He ◽  
Lisha Ai ◽  
Xin Liu ◽  
Hao Huang ◽  
Yuebin Li ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Drug Release ◽  
Cancer Cells ◽  
Therapeutic Effects ◽  
Release Behavior ◽  
Sustained Drug Release ◽  
Drug Release Behavior ◽  
Nir Laser

The NIR-laser-driven plasmonic photothermal and sustained drug release behavior of CuS–PTX/SiO2 nanocapsules show great synergistic chemo-photothermal therapeutic effects on cancer cells in vitro and in vivo.

Definition of a cavitation index for real time monitoring during in vitro liposomal drug release.

2008 ◽  
Vol 124 (4) ◽  
pp. 2485-2485
Author(s):  
Lucie Somaglino ◽  
Guillaume Bouchoux ◽  
Jean‐Louis Mestas ◽  
Adrien Matias ◽  
Jean‐Yves Chapelon ◽  
...  
Keyword(s):  
Drug Release ◽  
Real Time ◽  
Real Time Monitoring ◽  
Liposomal Drug ◽  
Definition Of

Intracellular GSH-responsive camptothecin delivery systems

2019 ◽  
Vol 43 (47) ◽  
pp. 18673-18684 ◽  
Author(s):  
Dan Zhang ◽  
Le Li ◽  
Xiaohui Ji ◽  
Yanhong Gao
Keyword(s):  
Real Time ◽  
Delivery Systems ◽  
Real Time Monitoring

Smart GSH-responsive camptothecin delivery systems for treatment of tumors and real-time monitoring in vivo and in vitro were described.

scholarly journals Practical bioinstrumentation developments for AC magnetic field-mediated magnetic nanoparticle heating applications

2018 ◽  
Author(s):  
Mahendran Subramanian ◽  
Arkadiusz Miaskowski ◽  
Ajit K. Mahapatro ◽  
Ondrej Hovorka ◽  
Jon Dobson
Keyword(s):  
Drug Release ◽  
Real Time ◽  
Thermal Imaging ◽  
Heat Dissipation ◽  
Temperature Measurements ◽  
Whole Body ◽  
Planar Coil ◽  
Release Analysis

AbstractHeat dissipation during magnetization reversal processes in magnetic nanoparticles (MNP), upon exposure to alternating magnetic fields (AMF), has been extensively studied in relation to applications in magnetic fluid hyperthermia (MFH). This current paper demonstrates the design, fabrication, and evaluation of an efficient instrument, operating on this principle, for use as (i) a non-contact, in vitro, real-time temperature monitor; (ii) a drug release analysis system (DRAS); (iii) a high flux density module for AMF-mediated MNP studies; and (iv) an in vivo coil setup for real-time, whole body thermal imaging. The proposed DRAS is demonstrated by an AMF-mediated drug release proof-of-principle experiment. Also, the technique described facilitates non-contact temperature measurements of specific absorption rate (SAR) as accurately as temperature measurements using a probe in contact with the sample. Numerical calculations estimating the absolute and root mean squared flux densities, and other MNP – AMF studies suggest that the proposed stacked planar coil module could be employed for calorimetry. Even though the proposed in vivo coil setup could be used for real-time, whole body thermal imaging (within the limitations due to issues of penetration depth), further design effort is required in order to enhance the energy transfer efficiency.

scholarly journals 181. Real-Time Monitoring of Transcription Factor Activity Using In Vitro and In Vivo Models of Cholestasis

2015 ◽  
Vol 23 ◽  
pp. S72
Author(s):  
Juliette M.K.M. Delhove ◽  
Dany Perocheau ◽  
Suzanne M.K. Buckley ◽  
Rajvinder Karda ◽  
Simon N. Waddington ◽  
...  
Keyword(s):  
Transcription Factor ◽  
Real Time ◽  
Transcription Factor Activity ◽  
Factor Activity ◽  
Real Time Monitoring ◽  
In Vivo Models
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