A dual stimuli responsive fluorescent probe carrier from a double hydrophilic block copolymer capped with β-cyclodextrin

A β-cyclodextrin terminated triblock copolymer with both hydrophilic temperature and pH sensitive segments was prepared and characterized in terms of self-assembling and encapsulation behaviors.

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Sticky ends in a self-assembling ABA triblock copolymer: the role of ureas in stimuli-responsive hydrogels

Molecular Systems Design & Engineering ◽

10.1039/c8me00063h ◽

2019 ◽

Vol 4 (1) ◽

pp. 91-102 ◽

Cited By ~ 5

Author(s):

Ryan T. Shafranek ◽

Joel D. Leger ◽

Song Zhang ◽

Munira Khalil ◽

Xiaodan Gu ◽

...

Keyword(s):

Self Assembly ◽

Viscoelastic Properties ◽

Triblock Copolymer ◽

Thermal Response ◽

Stimuli Responsive ◽

Self Assembling ◽

Polymeric Hydrogels ◽

Aba Triblock Copolymer ◽

Responsive Hydrogels

Directed self-assembly in polymeric hydrogels allows tunability of thermal response and viscoelastic properties.

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A Wide Range of pH-Sensitive Fluorescent Probe based on Responsive Double Hydrophilic Block Copolymer for Real-Time Intracellular pH Sensing in Water Samples

IOP Conference Series Materials Science and Engineering ◽

10.1088/1757-899x/562/1/012053 ◽

2019 ◽

Vol 562 ◽

pp. 012053

Author(s):

Zijuan Zhou

Keyword(s):

Block Copolymer ◽

Real Time ◽

Fluorescent Probe ◽

Intracellular Ph ◽

Water Samples ◽

Ph Sensitive ◽

Ph Sensing ◽

Wide Range

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An amphiphilic block copolymer conjugated with carborane and a NIR fluorescent probe for potential imaging-guided BNCT therapy

Polymer Chemistry ◽

10.1039/c6py00799f ◽

2016 ◽

Vol 7 (26) ◽

pp. 4411-4418 ◽

Cited By ~ 15

Author(s):

Zheng Ruan ◽

Le Liu ◽

Liyi Fu ◽

Tao Xing ◽

Lifeng Yan

Keyword(s):

Block Copolymer ◽

Fluorescent Probe ◽

Triblock Copolymer ◽

Near Infrared ◽

Chain Transfer ◽

Fluorescence Probe ◽

Reversible Addition ◽

Nir Fluorescence ◽

Ring Open ◽

Nir Dye

A carborane-containing triblock copolymer conjugated with a near infrared (NIR) fluorescence probe has been synthesized via reversible addition fragmentation chain transfer (RAFT), ring open polymerization (ROP), and conjugations of a cyanine NIR dye.

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Correction: A dual stimuli responsive fluorescent probe carrier from a double hydrophilic block copolymer capped with β-cyclodextrin

Polymer Chemistry ◽

10.1039/c6py90110g ◽

2016 ◽

Vol 7 (30) ◽

pp. 4983-4983

Author(s):

Guang Yang ◽

Zhen Yang ◽

Chengguang Mu ◽

Xiaodong Fan ◽

Wei Tian ◽

...

Keyword(s):

Block Copolymer ◽

Fluorescent Probe ◽

Stimuli Responsive

Correction for ‘A dual stimuli responsive fluorescent probe carrier from a double hydrophilic block copolymer capped with β-cyclodextrin’ by Guang Yang et al., Polym. Chem., 2015, 6, 3382–3386.

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Surface-Grafted Stimuli-Responsive Block Copolymer Brushes for the Thermo-, Photo- and pH-Sensitive Release of Dye Molecules

Macromolecules ◽

10.1021/ma2010102 ◽

2011 ◽

Vol 44 (18) ◽

pp. 7385-7393 ◽

Cited By ~ 95

Author(s):

Surjith Kumar ◽

Yves L. Dory ◽

Martin Lepage ◽

Yue Zhao

Keyword(s):

Block Copolymer ◽

Ph Sensitive ◽

Dye Molecules ◽

Stimuli Responsive ◽

Copolymer Brushes

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Combining Dextran Conjugates with Stimuli-Responsive and Folate-Targeting Activity: A New Class of Multifunctional Nanoparticles for Cancer Therapy

Nanomaterials ◽

10.3390/nano11051108 ◽

2021 ◽

Vol 11 (5) ◽

pp. 1108

Author(s):

Manuela Curcio ◽

Alessandro Paolì ◽

Giuseppe Cirillo ◽

Sebastiano Di Pietro ◽

Martina Forestiero ◽

...

Keyword(s):

Cancer Therapy ◽

Drug Release ◽

Metastatic Cancer ◽

Stimuli Responsive ◽

Cancer Disease ◽

New Class ◽

Self Assembling ◽

Redox Responsive ◽

Potential Applicability ◽

Mean Size

Nanoparticles with active-targeting and stimuli-responsive behavior are a promising class of engineered materials able to recognize the site of cancer disease, targeting the drug release and limiting side effects in the healthy organs. In this work, new dual pH/redox-responsive nanoparticles with affinity for folate receptors were prepared by the combination of two amphiphilic dextran (DEX) derivatives. DEXFA conjugate was obtained by covalent coupling of the polysaccharide with folic acid (FA), whereas DEXssPEGCOOH derived from a reductive amination step of DEX was followed by condensation with polyethylene glycol 600. After self-assembling, nanoparticles with a mean size of 50 nm, able to be destabilized in acidic pH and reducing media, were obtained. Doxorubicin was loaded during the self-assembling process, and the release experiments showed the ability of the proposed system to modulate the drug release in response to different pH and redox conditions. Finally, the viability and uptake experiments on healthy (MCF-10A) and metastatic cancer (MDA-MB-231) cells proved the potential applicability of the proposed system as a new drug vector in cancer therapy.

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