Single particle electrochemistry of p-hydroxythiophenol-labeled gold nanoparticles

RSC Advances ◽  
2015 ◽  
Vol 5 (61) ◽  
pp. 49031-49035 ◽  
Author(s):  
Jing Zhang ◽  
Yongfeng Wei ◽  
Lei Tian ◽  
Xiaofeng Kang

Electroactive p-hydroxythiophenol (p-HTP) monolayer on a gold nanoparticle surface produced an amplified single particle-collision electrochemical signal.

2014 ◽  
Vol 50 (18) ◽  
pp. 2289 ◽  
Author(s):  
Charles-Oneil L. Crites ◽  
Geniece L. Hallet-Tapley ◽  
María González-Béjar ◽  
J. C. Netto-Ferreira ◽  
Juan C. Scaiano

2021 ◽  
Author(s):  
M S S Vinod Mouli ◽  
Arpna Tamrakar ◽  
Mrituanjay D Pandey ◽  
Ashutosh Kumar Mishra

Herein, we report the functionalization of the gold nanoparticles with pyrene fluorophore via a connecting nucleobase spacer displaying the inherent photoluminescence behavior, without getting quenched by the gold nanoparticle surface...


Nanoscale ◽  
2015 ◽  
Vol 7 (9) ◽  
pp. 4250-4255 ◽  
Author(s):  
Chatdanai Lumdee ◽  
Binfeng Yun ◽  
Pieter G. Kik

The impact of nanoscale surface roughness on substrate-tuned gold nanoparticle plasmon resonances is demonstrated by comparing single-particle scattering spectra with simulated scattering spectra of gold nanoparticles on gold films with realistic roughness.


2019 ◽  
Vol 9 (22) ◽  
pp. 4782
Author(s):  
Berlina ◽  
Komova ◽  
Zherdev ◽  
Gaur ◽  
Dzantiev

A simple and rapid positive–negative colorimetric approach to determine the presence of antimony ions based on the use of gold nanoparticles conjugated with oligonucleotide (poly-A sequence) is developed. Colorimetric measurements reveal that the aggregates of modified gold nanoparticles were afforded after adding antimony ions, thus changing the solution color from pink to blue. The results of aptamer’s interaction on the gold nanoparticle surface with the target analyte can be detected either by photometry or by the naked eye. The realized assay provides rapid (2 min), sensitive (detection limit 10 ng/mL), specific, and precise (variation coefficient less than 3.8%) detection of antimony (III) in drinking water.


The Analyst ◽  
2020 ◽  
Vol 145 (24) ◽  
pp. 7932-7940
Author(s):  
Yuqian Xing ◽  
Juan Han ◽  
Xu Wu ◽  
David T. Pierce ◽  
Julia Xiaojun Zhao

An ultrasensitive biomarker assay platform established by monitoring the gold nanoparticles (AuNPs) desorbed away from graphene triggered by the target using single-particle inductively-coupled plasma/mass spectrometry (spICP-MS).


Author(s):  
Anna N. Berlina ◽  
Nadezhda S. Komova ◽  
Anatoly V. Zherdev ◽  
Mulayam S. Gaur ◽  
Boris B. Dzantiev

A simple and rapid positive–negative colorimetric approach to determine the presence of antimony ions based on the use of gold nanoparticles conjugated with oligonucleotide (poly-A sequence) is developed. Colorimetric measurements reveal that the aggregates of modified gold nanoparticles were afforded after adding antimony ions, thus changing the solution color from pink to blue. The results of aptamer’s interaction on the gold nanoparticle surface with target analyte can be detected either by photometry or by the naked eye. The realized assay provides rapid (2 min), sensitive (detection limit 10 ng/mL), specific, and precise (variation coefficient less than 3.8%) detection of antimony (III) in drinking water


2016 ◽  
Vol 52 (14) ◽  
pp. 2984-2987 ◽  
Author(s):  
Heng Song ◽  
Chao Jing ◽  
Wei Ma ◽  
Tao Xie ◽  
Yi-Tao Long

PRRS spectra of single gold nanoparticles show a reversible shift towards the photoswitchable reaction, which could be verified by DDA simulations.


Nanoscale ◽  
2019 ◽  
Vol 11 (8) ◽  
pp. 3665-3673 ◽  
Author(s):  
Hanane Moustaoui ◽  
Justine Saber ◽  
Ines Djeddi ◽  
Qiqian Liu ◽  
Dania Movia ◽  
...  

Gold nanoparticle interaction with proteins is characterized by using scattering correlation spectroscopy. Protein orientation and binding affinity regarding the nanoparticle surface are discussed.


2020 ◽  
Vol 16 (2) ◽  
pp. 204-213 ◽  
Author(s):  
Melissa A. Vetten ◽  
Mary Gulumian

Background: Endotoxin-free engineered nanoparticle suspensions are imperative for their successful applications in the field of nanomedicine as well as in the investigations in their toxicity. Gold nanoparticles are known to interfere with various in vitro assays due to their optical properties and potential for surface reactivity. In vitro endotoxin testing assays are known to be susceptible to interference caused by the sample being tested. Objective: This study aimed to identify a preferred assay for the testing of endotoxin contamination in gold nanoparticle suspensions. Methods: The interference by gold nanoparticles on three assays namely, the commonly used limulus amebocyte lysate chromogenic assay, the limulus amebocyte lysate gel-clot method, and the less common recombinant Factor C (rFC) assay, was tested. Results: Possible interference could be observed with all three assays. The interference with the absorbance- based chromogenic assay could not be overcome by dilution; whilst the qualitative nature of the gel-clot assay excluded the possibility of distinguishing between a false positive result due to enhancement of the sensitivity of the assay, and genuine endotoxin contamination. However, interference with the rFC assay was easily overcome through dilution. Conclusion: The rFC assay is recommended as an option for endotoxin contamination detection in gold nanoparticle suspensions.


2021 ◽  
Author(s):  
Yiren Cao ◽  
Jinjun Wu ◽  
Bo Pang ◽  
Hongquan Zhang ◽  
X. Chris Le

The trans-cleavage activity of the target-activated CRISPR-Cas12a liberated an RNA crosslinker from a molecular transducer, which facilitated assembly of gold nanoparticles. Integration of the molecular transducer with isothermal amplification and...


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