Fluorescence dye loaded nano-graphene for multimodal imaging guided photothermal therapy

Photoacoustic imaging (PA) has emerged as a novel and noninvasive imaging modality owing to its high spatial resolution and high soft tissue contrast.

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Multifunctional conjugated polymer nanoparticles for photoacoustic-based multimodal imaging and cancer photothermal therapy

Journal of Innovative Optical Health Sciences ◽

10.1142/s1793545819300015 ◽

2019 ◽

Vol 12 (03) ◽

pp. 1930001 ◽

Cited By ~ 6

Author(s):

Xiaoju Men ◽

Zhen Yuan

Keyword(s):

Conjugated Polymer ◽

Photothermal Therapy ◽

Multimodal Imaging ◽

Photoacoustic Imaging ◽

Biological Tissues ◽

Polymer Nanoparticles ◽

Imaging Method ◽

Conjugated Polymer Nanoparticles ◽

Good Biocompatibility ◽

Cancer Theranostics

Photoacoustic imaging (PAI) is a hybrid imaging method based on photoacoustic (PA) effects, which is able to capture the structure, function, and molecular information of biological tissues with high resolution. To date, therapeutic techniques under the guidance of PAI have provided new strategies for accurate diagnosis and precise treatment of tumors. In particular, conjugated polymer nanoparticles have been extensively inspected for PA-based cancer theranostics largely due to their superior optical properties such as tunable spectrum and large absorption coefficient and their good biocompatibility, and abundant functional groups. This mini-review mainly focuses on the recent advances toward the development of novel conjugated polymer nanoparticles for PA-based multimodal imaging and cancer photothermal therapy.

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Photoacoustic molecular imaging with functional nanoparticles

Journal of Innovative Optical Health Sciences ◽

10.1142/s179354581730004x ◽

2017 ◽

Vol 10 (04) ◽

pp. 1730004 ◽

Cited By ~ 3

Author(s):

Liming Liu ◽

Huan Qin

Keyword(s):

Molecular Imaging ◽

High Spatial Resolution ◽

Photoacoustic Imaging ◽

Imaging Modality ◽

Ultrasonic Waves ◽

Diffusion Limit ◽

Biological Processes ◽

Functional Nanoparticles ◽

Current Review ◽

Optical Nanoprobes

Photoacoustic imaging (PAI) breaks through the optical diffusion limit by making use of the PA effect. By converting incident photons into ultrasonic waves, PAI combines high contrast of optical imaging and high spatial resolution in depth tissue of ultrasound imaging in a single imaging modality. This imaging modality has now shown potential for molecular imaging, which enables visualization of biological processes with systemically introduced functional nanoparticles. In the current review, the potentials of different optical nanoprobes as PAI contrast agents were elucidated and discussed.

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A polydopamine-coated LAPONITE®-stabilized iron oxide nanoplatform for targeted multimodal imaging-guided photothermal cancer therapy

Journal of Materials Chemistry B ◽

10.1039/c9tb00398c ◽

2019 ◽

Vol 7 (24) ◽

pp. 3856-3864 ◽

Cited By ~ 4

Author(s):

Mengxue Liu ◽

Jiulong Zhang ◽

Xin Li ◽

Chao Cai ◽

Xueyan Cao ◽

...

Keyword(s):

Iron Oxide ◽

Sialic Acid ◽

Magnetic Resonance ◽

Cancer Therapy ◽

Cancer Cells ◽

Photothermal Therapy ◽

Multimodal Imaging ◽

Photoacoustic Imaging

A novel targeted theranostic nanoplatform (LAP–Fe3O4@PDA–PEG–PBA) is constructed for magnetic resonance and photoacoustic imaging-guided photothermal therapy of cancer cells overexpressing sialic acid.

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Internal Derangements of the Elbow

Musculoskeletal Imaging Volume 2 ◽

10.1093/med/9780190938178.003.0105 ◽

2019 ◽

pp. 192-209

Author(s):

Kathryn J. Stevens

Keyword(s):

Soft Tissue ◽

Soft Tissues ◽

Imaging Modality ◽

Joint Effusion ◽

Stress Injury ◽

Elbow Pain ◽

Traumatic Injuries ◽

Recreational Athletes ◽

Tissue Contrast ◽

Osteochondral Injury

Chapter 105 covers elbow pain, which is a common presenting complaint, particularly in professional or recreational athletes, and can result in significant morbidity. Although radiographs, US, and CT may have a role to play in the investigation of elbow pain, MRI with its high spatial resolution, excellent soft tissue contrast, and multiplanar imaging capabilities, has emerged as the imaging modality of choice for diagnosis of soft tissue pathology and osteochondral injury around the elbow. MRI is invaluable in the evaluation of acute traumatic injuries of bone and soft tissues structures, particularly if a joint effusion is detected radiographically. Articular cartilage is well seen on MRI, particularly in the presence of a joint effusion. MRI is also beneficial in the evaluation of chronic elbow pain and overuse injuries and can diagnose osseous stress injury, osteochondral pathology, ligamentous instability, nerve pathology, and denervation changes of muscle.

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Coronary imaging

The EACVI Textbook of Cardiovascular Magnetic Resonance ◽

10.1093/med/9780198779735.003.0019 ◽

2018 ◽

pp. 164-176

Author(s):

Claudia Prieto ◽

René M Botnar ◽

Hajime Sakuma ◽

Masaki Ishida ◽

Marcus R Makowski

Keyword(s):

Coronary Artery ◽

Spatial Resolution ◽

Coronary Arteries ◽

High Spatial Resolution ◽

Imaging Modality ◽

Coronary Plaque ◽

Suspected Coronary Artery Disease ◽

Detection And Tracking ◽

Tissue Contrast ◽

Artery Disease

Due to its high soft tissue contrast, high spatial resolution, and lack of ionizing radiation, cardiovascular magnetic resonance (CMR) is a promising imaging modality for non-invasive imaging of the coronary arteries. However, because of the high spatial resolution and large coverage required for visualization of the coronary arteries, scan times are relatively long. This can result in imaging artefacts from cardiac and respiratory motion. Usually, coronary CMR is therefore performed with respiratory and cardiac compensation methods. CMR has shown promising results for the detection of coronary stenosis, when compared against invasive and computed tomography coronary angiography, but in clinical practice, CMR is more often used to define the course of anomalous coronary arteries and for the detection and tracking of coronary artery aneurysms. CMR also allows imaging of the coronary vessel wall and coronary plaque imaging, as well as the detection of coronary thrombus. These emerging methods may have a future role in risk stratification of patients with known or suspected coronary artery disease.

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Myxofibrosarcoma: clinical and prognostic value of MRI features

Current Medical Imaging Formerly Current Medical Imaging Reviews ◽

10.2174/1573405616999200729152135 ◽

2020 ◽

Vol 16 ◽

Cited By ~ 1

Author(s):

Paolo Spinnato ◽

Andrea Sambri ◽

Tomohiro Fujiwara ◽

Luca Ceccarelli ◽

Roberta Clinca ◽

...

Keyword(s):

Soft Tissue ◽

Local Recurrence ◽

Contrast Enhancement ◽

Imaging Modality ◽

Soft Tissue Sarcomas ◽

The Elderly ◽

High Rate ◽

Imaging Features ◽

High Grade ◽

Mri Features

: Myxofibrosarcoma is one of the most common soft tissue sarcomas in the elderly. It is characterized by an extremely high rate of local recurrence, higher than other soft tissue tumors, and a relatively low risk of distant metastases.Magnetic resonance imaging (MRI) is the imaging modality of choice for the assessment of myxofibrosarcoma and plays a key role in the preoperative setting of these patients.MRI features associated with high risk of local recurrence are: high myxoid matrix content (water-like appearance of the lesions), high grade of contrast enhancement, presence of an infiltrative pattern (“tail sign”). On the other hand, MRI features associated with worse sarcoma specific survival are: large size of the lesion, deep location, high grade of contrast enhancement. Recognizing the above-mentioned imaging features of myxofibrosarcoma may be helpful to stratify the risk for local recurrence and disease-specific survival. Moreover, the surgical planning should be adjusted according to the MRI features

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