Noncovalent assembly of reduced graphene oxide and alkyl-grafted mesoporous silica: an effective drug carrier for near-infrared light-responsive controlled drug release

2015 ◽  
Vol 3 (27) ◽  
pp. 5588-5594 ◽  
Author(s):  
Dinggeng He ◽  
Xuecai Li ◽  
Xiaoxiao He ◽  
Kemin Wang ◽  
Jinlu Tang ◽  
...  

A novel NIR-responsive drug release system based on noncovalent assembly of reduced graphene oxide and alkyl-grafted mesoporous silica.

2020 ◽  
Vol 35 (1) ◽  
pp. 28-38
Author(s):  
Jieying Liao ◽  
Huicong Zhang ◽  
Xuandong Wang

Multifunctional nanocarriers have been widely accepted and utilized for biomedical applications, because of their structural regularity, convenient post-modification and controllable structure and morphology. Herein, we reported polydopamine-doped virus-like mesoporous silica coated reduced graphene oxide nanosheets (rGO@PVMSNs) nanocomposites by a facile oil–water biphase stratification method. The synthesized rGO@PVMSNs nanocomposites performed excellent biocompatibility and photothermal performance. They could be employed as photoacoustic imaging contrast in vivo. Furthermore, the rGO@PVMSNs nanocarriers were used for loading the antitumor drug doxorubicin (DOX), the rGO@PVMSNs@DOX nanocomposites were also demonstrated to be with high inhibition of HepG2 cancer cells, especially with the help of near-infrared irradiation, which were more efficient than single chemotherapy or photothermal therapy. The rGO@PVMSNs@DOX nanocomposites of this work could be used as photoacoustic imaging and chemo-photothermal synergetic therapy agents, which show a new perspective for clinical tumor diagnosis and therapy.


2020 ◽  
Vol 3 (5) ◽  
pp. 2577-2587 ◽  
Author(s):  
Xiao Liu ◽  
Xu Wu ◽  
Yuqian Xing ◽  
Ying Zhang ◽  
Xuefei Zhang ◽  
...  

2021 ◽  
Vol 418 ◽  
pp. 129343
Author(s):  
Ya Zhang ◽  
Huihui Zhou ◽  
Honggui Wang ◽  
Yongcai Zhang ◽  
Dionysios D. Dionysiou

2018 ◽  
Vol 6 (21) ◽  
pp. 3531-3540 ◽  
Author(s):  
Jun Xiang ◽  
Xia Tong ◽  
Feng Shi ◽  
Qiang Yan ◽  
Bing Yu ◽  
...  

The preparation of a new near-infrared (NIR) light-responsive nanocarrier for controlled drug release is demonstrated.


RSC Advances ◽  
2018 ◽  
Vol 8 (66) ◽  
pp. 37623-37630 ◽  
Author(s):  
Qingli Huang ◽  
MingYan Li ◽  
LiLi Wang ◽  
Honghua Yuan ◽  
Meng Wang ◽  
...  

The rGO@CD@PEG@FA nanocomposite showed the stimulative effect of heat, pH response, and sustained drug release for cancer therapy


2016 ◽  
Vol 33 (6) ◽  
pp. 316-322 ◽  
Author(s):  
Haosha Tang ◽  
Liangqing Yao ◽  
Jianping Yang ◽  
Wei Li ◽  
Zhaogang Teng ◽  
...  

Soft Matter ◽  
2018 ◽  
Vol 14 (12) ◽  
pp. 2400-2410 ◽  
Author(s):  
Samira Malekmohammadi ◽  
Hassan Hadadzadeh ◽  
Hossein Farrokhpour ◽  
Zahra Amirghofran

A nanocarrier for curcumin targeted delivery and cell imaging was prepared by immobilization of gold NPs on the folic acid-modified dendritic mesoporous silica-coated reduced graphene oxide nanosheets.


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