scholarly journals Olive leaf extract concentrated in hydroxytyrosol attenuates protein carbonylation and the formation of advanced glycation end products in a hepatic cell line (HepG2)

2017 ◽  
Vol 8 (3) ◽  
pp. 944-953 ◽  
Author(s):  
Marta Navarro ◽  
Francisco J. Morales ◽  
Sonia Ramos
2014 ◽  
Vol 56 (2) ◽  
pp. 93
Author(s):  
Izaak Akbar ◽  
Nur Permatasari ◽  
Djoko Soeatmadji ◽  
Mohammad Hidayat ◽  
Handono Kalim

2001 ◽  
Vol 16 (8) ◽  
pp. 1562-1569 ◽  
Author(s):  
Guangsheng Xiang ◽  
Reinhard Schinzel ◽  
Andreas Simm ◽  
Gerald Münch ◽  
Katarina Sebekova ◽  
...  

2017 ◽  
Vol 6 (2) ◽  
pp. 102 ◽  
Author(s):  
Kimihisa Itoh ◽  
Kazuya Murata ◽  
Nao Sakaguchi ◽  
Kohei Akai ◽  
Tomoka Yamaji ◽  
...  

The purpose of this study was to examine an inhibitory effect of mango leaf extracts on advanced glycation end products (AGEs) formation and to identify these active ingredients, and also to investigate a relationship between leaves maturation and the inhibitory activity. A methanolic extract of old dark green mango leaf extract (OML-ext) exhibited an inhibitory activity of AGEs formation in nonenzymatic glycation of albumin. The inhibitory activity of OML-ext was attributable to 3-C-β-D-glucosyl-2,4,4’,6-tetrahydroxybenzophenone (1), mangiferin (2) and chlorophyll. Inhibitory effect of young dark reddish brown mango leaf extract (YDL-ext) on AGEs formation was similar to that of OML-ext. The inhibitory activity of YDL-ext was attributable to 1 and 2, in addition, a part of the the activity of YDL-ext due to anthocyanins whose content is highest in young dark reddish brown mango leaves. Considering the amounts of leaves obtained from pruning, old dark green leaves may be a reasonable natural resource for the preparation of ingredients with inhibitory activity of AGEs formation.


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