Poly-γ-glutamic acid-based GGT-targeting and surface camouflage strategy for improving cervical cancer gene therapy

2017 ◽  
Vol 5 (6) ◽  
pp. 1315-1327 ◽  
Author(s):  
Jiao Tan ◽  
Huiyuan Wang ◽  
Fan Xu ◽  
Yingzhi Chen ◽  
Meng Zhang ◽  
...  

A γ-PGA-based GGT-targeting and surface camouflage strategy for constructing a ternary layer-by-layer self-assembly gene delivery system.

1999 ◽  
Vol 42 (2) ◽  
pp. 216-224 ◽  
Author(s):  
Peikun Tian ◽  
Shengjun Ren ◽  
Changchun Ren ◽  
Qingshan Teng ◽  
Shumin Qu ◽  
...  

2002 ◽  
Vol 9 (4) ◽  
pp. 365-371 ◽  
Author(s):  
Anders Høgset ◽  
Birgit Øvstebø Engesæter ◽  
Lina Prasmickaite ◽  
Kristian Berg ◽  
Øystein Fodstad ◽  
...  

2005 ◽  
Vol 0 (0) ◽  
pp. 060123080936012
Author(s):  
Katie L. Green ◽  
Tom D. Southgate ◽  
Kate Mulryan ◽  
Lez J. Fairbairn ◽  
Peter L. Stern ◽  
...  

2003 ◽  
Vol 2003 (2) ◽  
pp. 110-137 ◽  
Author(s):  
Tracy Robson ◽  
David G. Hirst

Cancer gene therapy has been one of the most exciting areas of therapeutic research in the past decade. In this review, we discuss strategies to restrict transcription of transgenes to tumour cells. A range of promoters which are tissue-specific, tumour-specific, or inducible by exogenous agents are presented. Transcriptional targeting should prevent normal tissue toxicities associated with other cancer treatments, such as radiation and chemotherapy. In addition, the specificity of these strategies should provide improved targeting of metastatic tumours following systemic gene delivery. Rapid progress in the ability to specifically control transgenes will allow systemic gene delivery for cancer therapy to become a real possibility in the near future.


2009 ◽  
Vol 10 (1) ◽  
pp. 73-88 ◽  
Author(s):  
Jin Xu ◽  
Chen Jin ◽  
Sijie Hao ◽  
Guopei Luo ◽  
Deliang Fu

1998 ◽  
Vol 22 (5) ◽  
pp. 445-454 ◽  
Author(s):  
Richard J. Cristiano ◽  
Bo Xu ◽  
Dao Nguyen ◽  
Guido Schumacher ◽  
Masafumi Kataoka ◽  
...  

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