scholarly journals MAO inhibitory activity of bromo-2-phenylbenzofurans: synthesis, in vitro study, and docking calculations

MedChemComm ◽  
2017 ◽  
Vol 8 (9) ◽  
pp. 1788-1796 ◽  
Author(s):  
G. L. Delogu ◽  
F. Pintus ◽  
L. Mayán ◽  
M. J. Matos ◽  
S. Vilar ◽  
...  

Monoamine oxidase (MAO) is an enzyme responsible for metabolism of monoamine neurotransmitters which play an important role in brain development and function.

ChemMedChem ◽  
2013 ◽  
Vol 8 (6) ◽  
pp. 956-966 ◽  
Author(s):  
Giulio Ferino ◽  
Enzo Cadoni ◽  
Maria João Matos ◽  
Elias Quezada ◽  
Eugenio Uriarte ◽  
...  

2016 ◽  
Vol 17 (1) ◽  
Author(s):  
Olivia Freynet ◽  
Joëlle Marchal-Sommé ◽  
Francette Jean-Louis ◽  
Arnaud Mailleux ◽  
Bruno Crestani ◽  
...  

2010 ◽  
Vol 42 (5) ◽  
pp. 280 ◽  
Author(s):  
A Mitra ◽  
IniyanG Tamil ◽  
B Dineshkumar ◽  
M Nandhakumar ◽  
M Senthilkumar

2011 ◽  
Vol 60 (11) ◽  
pp. 675-681 ◽  
Author(s):  
Pier Braga ◽  
Monica Sasso ◽  
Maria Culici ◽  
Alessandra Spallino

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Naoya Ikemura ◽  
Yuji Sato ◽  
Junichi Furuya ◽  
Osamu Shimodaira ◽  
Kana Takeda ◽  
...  

Abstract Background It is difficult to maintain complete dentures during meals in place. This in vitro study aimed to assess changes in denture retention between rest and function using denture adhesives and oral moisturizers in an oral cavity model. Methods The following test samples were applied between the palatal plate and the edentulous jaw ridge model: denture adhesive, denture adhesive for dry mouth, oral moisturizer, and denture moisturizer. The retentive force was measured under two conditions: at rest while immersed in water and during function with a 2.5-kg load applied. The plate was pulled perpendicular to the occlusal plane and the retentive force was measured using a digital force gauge. Results Under dry conditions, denture adhesive for dry mouth and oral moisturizer had a significantly higher retentive force than denture adhesive and denture moisturizer. After 30 min of immersion in water, the retentive force of the denture adhesive increased while that of the oral moisturizer decreased. After 30 min of function, the retentive force of the denture adhesive and denture adhesive for dry mouth remained high, while that of the oral moisturizer and denture moisturizer significantly decreased. Between rest and function, the retentive force of the denture adhesive and denture adhesive for dry mouth was high, and that of the oral moisturizer was low. Conclusions Immediately after use, denture adhesive for dry mouth exhibited high retentive force, but retention gradually decreased due to its water content.


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